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| 1 | 5-羟色胺与结肠动力关系研究显示文摘5-羟色胺(5-HT)参与调节肠道多种功能。5-HT制剂广泛用于临床治疗结肠动力相关性疾病,但具体作用机制不甚清楚。本文围绕5-HT与结肠动力的关系进行综述。 | 俞媛洁 陈继红 罗和生 Jan D Huizinga | 2014 | 胃肠病学和肝病学杂志2014，23，1： | 8 |
| 2 | 胃结肠反射的研究概况显示文摘胃结肠反射是胃肠道生理现象之一,参与功能性胃肠疾病的发生和发展,具有潜在的临床价值。胃结肠反射的研究方法主要为肌电图和结肠测压法,可见餐后结肠尖峰突发波或结肠动力指数增加。近年应用测压法发现餐后结肠具有特定的运动模式,但胃结肠反射的表现方式和机制仍不清楚。本文就胃结肠反射的研究概况作一综述。 | 黄敏 陈继红 谭诗云 罗和生 Jan D HUIZINGA | 2016 | 胃肠病学2016，21，8： | 5 |
| 3 | Rheumatoid arthritis显示文摘 | David L Scott Frederick Wolfe Tom WJ Huizinga | 2010 | The Lancet2010，，9746： | 3 |
| 4 | TNFα polymorphisms in RA: association with susceptibility to, or severity of disease显示文摘 | Brinkman BMN Huizinga TWJ Kurban SS | 1996 | Eur Cytokine Netw1996，7，： | 2 |
| 5 | TNFα promoter polymorphism, production and susceptibility to multiple sclerosis in different groups of patients显示文摘 | Huizinga TWJ Westendorp RGJ Bollen LEM | 1997 | J Neuroimmunol1997，72，： | 2 |
| 6 | Physiology, Injury, and Recovery of Interstitial Cells of Cajal: Basic and Clinical Science显示文摘 | Jan D. Huizinga Natalia Zarate Gianrico Farrugia | 2009 | Gastroenterology2009，，5： | 2 |
| 7 | Cerebral magnetic resonance imaging in quiescent Crohn's disease patients with fatigue显示文摘AIM To evaluate brain involvement in quiescent Crohn's disease (CD) patients with fatigue using quantitative magnetic resonance imaging(MRI).METHODS Multiple MRI techniques were used to assess cerebral changes in 20 quiescent CD patients with fatigue(defined with at least 6 points out of an 11-point numeric rating scale compared with 17 healthy age and gender matched controls without fatigue. Furthermore, mental status was assessed by cognitive functioning, based on the neuropsychological inventory including the different domains global cognitive functioning, memory and executive functioning and in addition mood and quality of life scores. Cognitive functioning and mood status were correlated with MRI findings in the both study groups.RESULTS Reduced glutamate + glutamine (Glx = Glu + Gln) concentrations (P = 0.02) and ratios to total creatine(P = 0.02) were found in CD patients compared with controls. Significant increased Cerebral Blood Flow(P = 0.05) was found in CD patients (53.08 ± 6.14 mL/100 g/min) compared with controls (47.60 ± 8.62 mL/100 g/min). CD patients encountered significantly more depressive symptoms (P < 0.001). Cognitive functioning scores related to memory (P = 0.007) and executive functioning (P = 0.02) were lower in CD patients and both scores showed correlation with depression and anxiety. No correlation was found subcortical volumes between CD patients and controls in the T1-weighted analysis. In addition, no correlation was found between mental status and MRI findings.CONCLUSION This work shows evidence for perfusion, neurochemical and mental differences in the brain of CD patients with fatigue compared with healthy controls. | Sanne van Erp Ece Ercan Perla Breedveld Lianne Brakenhoff Eidrees Ghariq Sophie Schmid Matthias van Osch Mark van Buchem Bart Emmer Jeroen van der Grond Ron Wolterbeek Daniel Hommes Herma Fidder Nic van der Wee Tom Huizinga Désirée van der Heijde Huub Middelkoop Itamar Ronen Andrea van der Meulen-de Jong | 2017 | World Journal of Gastroenterology2017，23，6： | 2 |
| 8 | 显示文摘 | CLAESSENS S DEMIRGUC-KUNT A HUIZINGA H: How does Foreign Entry Affect the Domestic Banking Market? | 2001 | Journal of Banking and Finance2001，25，： | 1 |
| 9 | Kit gene required for interstitial cells of cajal and for intestinal pacemaker activity显示文摘 | Huizinga JD Thuneberg L Kluppel M | 1995 | Nature1995，373，34： | 1 |
| 10 | Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors显示文摘 | Sircar K Hewlett BR Huizinga JD | 1999 | Am J Surg Pathol1999，23，4： | 1 |
| 11 | Determinants of Commercial Bank Interest Margins and Profitability: Some International Evidence 显示文摘 | Demirguc- Kunt Asli & Harry Huizinga | 1999 | The World Bank Economic Review1999，，13： | 1 |
| 12 | Association of numeraey and diabetes control显示文摘 | Cavanaugh K Huizinga M M Wallston K A | 2008 | Ann Intern Med2008，148，10： | 1 |
| 13 | Rheumatoid arthritis 显示文摘 | SCOTT DL WOLFE F HUIZINGA TW | 2010 | Lancet2010，376，9746： | 1 |
| 14 | The search for the origin of rhythmicity in intestinal contraction from tissue to single cells显示文摘 | Huizinga JD Robinson TL Thomsen L | 2000 | Neurogastroenterol Motil2000，12，： | 1 |
| 15 | Clotrimazole-sensitive K^+ currents regulate pacemaker activity in interstitial cells of Cajal显示文摘 | Zhu Y Ye J Huizinga JD | 2007 | Am J Physiol Gastrointest Liver Physiol2007，292，6： | 1 |
| 16 | Interstitial cells of Cajal as precursors for gastrointestinal stromal tumors显示文摘 | Sircar K Hewlett BR Huizinga JD | 1999 | Am J Surg Pathol1999，23，： | 1 |
| 17 | Interstitial cells of Cajal as precursors for gastrointestinal stromal tumors 显示文摘 | Sircar K Hewlett BR Huizinga JD | 1999 | Am J Surg Pathol1999，23，： | 1 |
| 18 | Genetic predisposition of the severity of joint destruction in rheumatoid arthritis:a population-based study 显示文摘 | Knevel R Grondal G Huizinga TW | 2012 | Ann Rheum Dis2012，71，5： | 1 |
| 19 | Mukiple oil families in the West Siberian Basin 显示文摘 | PETERS K E KONTOROVICH A E HUIZINGA B J | 1994 | AAPG Bulletin1994，78，6： | 1 |
| 20 | Rheumatoid arthritis显示文摘 | Scott DL Wolfe F Huizinga TW | 2010 | Lancet2010，376，9746： | 1 |
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