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| 1 | RNA N^6-methyladenosine modification in cancers: current status and perspectives显示文摘 | Xiaolan Deng Rui Su Hengyou Weng Huilin Huang Zejuan Li Jianjun Chen | 2018 | Cell Research2018，28，5： | 55 |
| 2 | Glacier area variation and climate change in the Chinese Tianshan Mountains since 1960显示文摘基于自从 1960,在中国 Tianshan 山测量的冰河区域变化的统计,到气候变化的冰河区域变化的反应系统地被讨论。作为结果,冰河的全部的区域被 11.5% 在过去的 50 年里减少了,它根据中国(GIC ) 的冰河库存分开的 10 排水盆的冰河区域变化是一个加权的百分比。在中国 Tianshan 山的冰河的区域变化(APAC ) 的年度百分比在学习时期的标准化以后是 0.31% 。APAC 为不同排水盆广泛地变化,但是冰河通常处于快速的撤退的一个国家。根据在中国 Tianshan 山的 14 个气象学的车站,温度和降水以 0.34 整湲椠 ? 潮 ?湵晩牯 m 的率从 1960 ~ 2009 | WANG Shengjie ZHANG Mingjun LI Zhongqin WANG Feiteng LI Huilin LI Yaju HUANG Xiaoyan | 2011 | Journal of Geographical Sciences2011，21，2： | 31 |
| 3 | High matrix metalloproteinase-9 expression induces angiogenesis and basement membrane degradation in stroke-prone spontaneously hypertensive rats after cerebral infarction显示文摘Basement membrane degradation and blood-brain barrier damage appear after cerebral infarction, severely impacting neuronal and brain functioning; however, the underlying pathogenetic mechanisms remain poorly understood. In this study, we induced cerebral infarction in strokeprone spontaneously hypertensive rats by intragastric administration of high-sodium water(1.3% NaCl) for 7 consecutive weeks. Immunohistochemical and immunofluorescence assays demonstrated that, compared with the non-infarcted contralateral hemisphere, stroke-prone spontaneously hypertensive rats on normal sodium intake and Wistar-Kyoto rats, matrix metalloproteinase-9 expression, the number of blood vessels with discontinuous collagen IV expression and microvessel density were significantly higher, and the number of continuous collagen IV-positive blood vessels was lower in the infarct border zones of stroke-prone spontaneously hypertensive rats given high-sodium water. Linear correlation analysis showed matrix metalloproteinase-9 expression was positively correlated with the number of discontinuously collagen IV-labeled blood vessels and microvessel density in cerebral infarcts of stroke-prone spontaneously hypertensive rats. These results suggest that matrix metalloproteinase-9 upregulation is associated with increased regional angiogenesis and degradation of collagen IV, the major component of the basal lamina, in stroke-prone spontaneously hypertensive rats with high-sodium water-induced focal cerebral infarction. | Huilian Hou Guanjun Zhang Hongyan Wang Huilin Gong Chunbao Wang Xuebin Zhang | 2014 | Neural Regeneration Research2014，9，11： | 30 |
| 4 | Identifying paleoflood deposits archived in Zhongba Site,the Three Gorges reservoir region of the YangtzeRiver,China显示文摘Based on the principle that the present is the key to the past , detailed analyses, such as AMS 14C dating, grain size, component and morphology of heavy minerals, micro-morphology of zircon, Rb/Sr, magnetic susceptibility and total organic carbon (TOC), were conducted to identify paleoflood sediments archived in Zhongba Site. The results indicate that the plaeoflood sediments bear great similarities with modern flood sediments in the following aspects: (1) probability cumulative curves mainly show a pattern of 3―4 segments; (2) grain-size distribution of suspended matter ranges between 3 and 10Ф; (3) the sediments are well-sorted, most of which are suspended matter (>50%); (4) the same species, quantity and morphology of heavy minerals; (5) scanning electronic microscope images show that shapes of zircon are mainly oval and nearly spheral, rounded due to long-distance transport; (6) higher Rb/Sr values (0.55―0.66)than those of sediments from cultural layers (0.03―0.26); (7) magnetic susceptibility values (133.73―433.05 10-6m3/kg) are lower than those of sediments from cultural layers (959.25―2442.44 10?6 m3/kg); (8) TOC (0.14%―0.33%) are lower than those of sediments from cultural lay-ers (1.13%―2.95%). Our results demonstrate that, except for the 1981 flood, there are at least six paleoflood events that occurred during the Qing Dynasty, the middle of Song Dy-nasty, the early Warring States (400BC―350BC), the West Zhou Dynasty (920BC―900BC), the Xia Dynasty (2070BC―1600BC), and the late Neolithic Age (3000BC―2300BC), respectively . | ZHU Chen ZHENG Chaogui MA Chunmei SUN Zhibin ZHU Guangyao WANG Huilin GAO Huazhong WANG Pengling HUANG Run | 2005 | Chinese Science Bulletin2005，50，21： | 28 |
| 5 | Strong law of large numbers for Markov chains indexed by an infinite tree with uniformly bounded degree显示文摘In this paper,we study the strong law of large numbers and Shannon-McMillan (S-M) theorem for Markov chains indexed by an infinite tree with uniformly bounded degree.The results generalize the analogous results on a homogeneous tree. | HUANG HuiLin~1 YANG WeiGuo~(2+) 1 Department of Mathematics,Shanghai Jiaotong University,Shanghai 200240,China 2 Faculty of Science,Jiangsu University,Zhenjiang 212013,China | 2008 | Science China Mathematics2008，51，2： | 23 |
| 6 | Collagen scaffolds modified with collagen-binding bFGF promotes the neural regeneration in a rat hemisected spinal cord injury model显示文摘Nerve conduit is one of strategies for spine cord injury(SCI)treatment.Recently,studies showed that biomaterials could guide the neurite growth and promote axon regeneration at the injury site.However,the scaffold by itself was difficult to meet the need of SCI functional recovery.The basic fibroblast growth factor(bFGF)administration significantly promotes functional recovery after organ injuries.Here,using a rat model of T9 hemisected SCI,we aimed at assessing the repair capacity of implantation of collagen scaffold(CS)modified by collagen binding bFGF(CBD-bFGF).The results showed that CS combined with CBD-bFGF treatment improved survival rates after the lateral hemisection SCI.The CS/CBD-bFGF group showed more significant improvements in motor than the simply CS-implanted and untreated control group,when evaluated by the 21-point Basso-Beattie-Bresnahan(BBB)score and footprint analysis.Both hematoxylin and eosin(H&E)and immunohistochemical staining of neurofilament(NF)and glial fibrillary acidic protein(GFAP)demonstrated that fibers were guided to grow through the implants.These findings indicated that administration of CS modified with CBD-bFGF could promote spinal cord regeneration and functional recovery. | SHI Qin GAO Wei HAN XingLong ZHU XueSong SUN Jie XIE Fang HOU XiangLin YANG HuiLin DAI JianWu CHEN Liang | 2014 | Science China(Life Sciences)2014，57，2： | 23 |
| 7 | One-year clinical study of NeuroR egen scaffold implantation following scar resection in complete chronic spinal cord injury patients显示文摘The objective of this clinical study was to assess the safety and feasibility of the collagen scaffold, Neuro Regen scaffold, one year after scar tissue resection and implantation. Scar tissue is a physical and chemical barrier that prevents neural regeneration. However, identification of scar tissue is still a major challenge. In this study, the nerve electrophysiology method was used to distinguish scar tissue from normal neural tissue, and then different lengths of scars ranging from 0.5–4.5 cm were surgically resected in five complete chronic spinal cord injury(SCI) patients. The NeuroR egen scaffold along with autologous bone marrow mononuclear cells(BMMCs), which have been proven to promote neural regeneration and SCI recovery in animal models, were transplanted into the gap in the spinal cord following scar tissue resection. No obvious adverse effects related to scar resection or Neuro Regen scaffold transplantation were observed immediately after surgery or at the 12-month follow-up. In addition, patients showed partially autonomic nervous function improvement, and the recovery of somatosensory evoked potentials(SSEP) from the lower limbs was also detected. The results indicate that scar resection and Neuro Regen scaffold transplantation could be a promising clinical approach to treating SCI. | Zhifeng Xiao Fengwu Tang Jiaguang Tang Huilin Yang Yannan Zhao Bing Chen Sufang Han Nuo Wang Xing Li Shixiang Cheng Guang Han Changyu Zhao Xiaoxiong Yang Yumei Chen Qin Shi Shuxun Hou Sai Zhang Jianwu Dai | 2016 | Science China(Life Sciences)2016，59，7： | 18 |
| 8 | Characteristics of paleoflood deposits archived in unit T0403 of Yuxi Site in the Three Gorges reservoir areas,China显示文摘Based on the detailed analyses,multi-proxies such as AMS 14 C dating,grain size,component and morphology of heavy minerals,micromorphology of zircon,magnetic susceptibility,Rb/Sr and Hg content are used to research the paleoflood sediments archived in the Yuxi Site.The research indicates that, since 7.6 kaBP,at least 16 times of paleoflood with water level above Wusong Elevation 147.024 m(a.s.l.) left deposits in the Neolithic layers of unit T0403 from the Yuxi Site.The results are induced from the following aspects:(1)The plaeoflood sediments take on great similarities with modern flood sediments in the Yuxi Site and Zhongba Site in probability cumulative curves which mainly show a pattern of 3 segments in fluvial pattern.(2)There is some resemblance between the heavy mineral components and the zircon shape characteristics of paleoflood deposits and those of modern flood deposits.(3) Magnetic susceptibility values(40.44―70.10SI)are lower than those of sediments from cultural layers (59.59―188.68SI).(4)Hg values(290.71―742.51 ng/g)are lower than those of sediments from cultural layers(344.16―10518.17 ng/g).(5)Rb/Sr values are higher than those of sediments from cultural layers, while those of the 4th,5th,6th,7th,8th cultural layers are high,which shows that they are inundated by paleoflood.The reason for many flood deposits existing is related to the site situated on the first terrace where the Yuxi River joins with the Yangtze River.As there are some similarities between the plaeoflood sediments and those of the Zhongba Site,it is feasible to confirm the existence of paleoflood sediments based on the above points. | ZHU Cheng MA ChunMei XU WeiFeng BAI JiuJiang ZHENG ChaoGui ZHU GuangYao WANG HuiLin CHEN Ye LU XueFeng | 2008 | Chinese Science Bulletin2008，53，S1： | 16 |
| 9 | Human placenta-derived mesenchymal stem cells loaded on linear ordered collagen scaffold improves functional recovery after completely transected spinal cord injury in canine显示文摘Traumatic spinal cord injury(SCI) is a major challenge in the clinic. In this study, we sought to examine the synergistic effects of linear ordered collagen scaffold(LOCS) and human placenta-derived mesenchymal stem cells(hPMSCs) when transplanted into completely transected beagle dogs. After 36 weeks observation, we found that LOCS+hPMSCs implants promoted better hindlimb locomotor recovery than was observed in the non-treatment(control) group and LOCS group. Histological analysis showed that the regenerated tissue after treatment was well integrated with the host tissue, and dramatically reduced the volume of cystic and chondroitin sulfate proteoglycans(CSPGs) expression. Furthermore, the LOCS+hPMSCs group also showed more neuron-specific βIII-tubulin(Tuj-1)-and NeuN-positive neurons in the lesion area, as well as axonal regeneration, remyelination and synapse formation in the lesion site. Additionally, dogs in the LOCS+hPMSCs group experienced enhanced sprouting of both ascending(CGRP-positive) sensory fibers and descending(5-HT-and TH-positive) motor fibers at the lesion area. All these data together suggested that the combined treatment had beneficial effects on neuronal regeneration and functional improvement in a canine complete transection model. Therefore, LOCS+hPMSCs implantation holds a great promise for bridging the nerve defect and may be clinically useful in the near future. | Sufang Han Zhifeng Xiao Xing Li Huan Zhao Bin Wang Zhixue Qiu Zhi Li Xin Mei Bai Xu Caixia Fan Bing Chen Jin Han Yanzheng Gu Huilin Yang Qin Shi Jianwu Dai | 2018 | Science China(Life Sciences)2018，61，1： | 15 |
| 10 | Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway显示文摘Rheumatoid arthritis(RA)is a chronic inflammatory disease that eventually leads to disability.Inflammatory cell infiltration,severe joint breaking and systemic bone loss are the main clinical symptoms.In this study,we established a collagen-induced arthritis(CIA)model and found a large number of M1 macrophages and pyroptosis,which are important sources of proinflammatory cytokines.Punicalagin(PUN)is an active substance extracted from pomegranate peel.We found that it inhibited joint inflammation,cartilage damage and systemic bone destruction in CIA mice.PUN effectively alleviated the high expression of inflammatory cytokines in synovial tissue in vivo.PUN treatment shifted macrophages from the M1 phenotype to the M2 phenotype after stimulation with lipopolysaccharide(LPS)and interferon(IFN)-γ.The expression of inducible nitric oxide synthase(i NOS)and other proinflammatory cytokines released by M1 macrophages was decreased in the PUN treatment group.However,simultaneously,the expression of markers of anti-inflammatory M2 macrophages,such as arginase(Arg)-1 and interleukin(IL)-10,was increased.In addition,PUN treatment attenuated pyroptosis by downregulating the expression of NLRP3 and caspase-1,thereby preventing inflammatory cell death resulting from the release of IL-1βand IL-18.Mechanistically,PUN inhibited the activation of receptor activators of the nuclear factor-κB(NF-κB)signaling pathway,which contributes to M1 polarization and pyroptosis of macrophages.We concluded that PUN ameliorated pathological inflammation by inhibiting M1 phenotype polarization and pyroptosis and has great potential as a therapeutic treatment for human RA. | Gaoran Ge Jiaxiang Bai Qing Wang Xiaolong Liang Huaqiang Tao Hao Chen Minggang Wei Junjie Niu Huilin Yang Yaozeng Xu Yuefeng Hao Yi Xue Dechun Geng | 2022 | Science China(Life Sciences)2022，65，3： | 14 |
| 11 | Eocrinoid echinoderms from the Lower Cambrian Guanshan Fauna in Wuding,Yunnan,China显示文摘This is a brief report of a new occurrence of eocrinoids from the Early Cambrian Wulongqing Formation in Yunnan, China. The eocrinoids from the Guanshan fauna are among the earliest known eocrinoids. Different from many other Early and Middle Cambrian eocrinoids, the Guanshan eocrinoids are char-acterized by the absence of sutural pores and epispires, the long and spiral brachioles, the extremely long stalk, and the ratio of the length of the stalk versus that of the calyx. The discovery of the eocri-noids from the Guanshan fauna not only provides new information to the investigation of the early evolution of this animal group, but also shed new light on the occurrence and migration of early eocrinoids. | HU ShiXue LUO HuiLin HOU ShuGuang Bernd-Dietrich ERDTMANN | 2007 | Chinese Science Bulletin2007，52，5： | 13 |
| 12 | Cigarette Smoking Increases Risk for Incident Metabolic Syndrome in Chinese Men—Shanghai Diabetes Study显示文摘Objective To determine whether smoking increases the risk for developing metabolic syndrome (MetS) in Chinese men.Methods A total of 693 men with no MetS at baseline were followed for 2.9‐5.5 years.Subjects were divided into nonsmokers,ex‐smokers,and current smokers according to baseline smoking status.Results After adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR index,and BMI at baseline and weight change,current smokers were dose‐dependently associated with increased risk for developing new MetS compared with nonsmokers.The odds ratio (OR) was 2.131 (95% CI,1.264,3.592;P<0.01) for the NCEPIII definition or 3.083 (95% CI,1.807,5.295;P<0.01) for the JCDCG definition of MetS.Ex‐smokers who had quit for ≥13 years significantly decreased the risk for developing new MetS defined by the JCDCG definition.Compared with nonsmokers,current smokers were significantly associated with increased incidence of hypertriglyceridemia and low HDL‐C.Conclusion Smoking is a risk factor for developing MetS in Chinese men after adjusting for age,education level,alcohol intake,fasting plasma insulin,HOMA‐IR,BMI,and weight change.This could be due to an increased incidence of dyslipidemia.Smoking cessation for >13 years decreased the risk for developing MetS defined by the JCDCG definition. | ZHU YunXia ZHANG MingLiang HOU XuHong LU JunXi PENG LiangPu GU HuiLin WANG Chen JIA WeiPing | 2011 | Biomedical and Environmental Sciences2011，24，5： | 13 |
| 13 | The effect of the fibre orientation of electrospun scaffolds on the matrix production of rabbit annulus fibrosus-derived stem cells显示文摘Annulus fibrosus(AF) tissue engineering has recently received increasing attention as a treatment for intervertebral disc(IVD) degeneration; however, such engineering remains challenging because of the remarkable complexity of AF tissue. In order to engineer a functional AF replacement, the fabrication of cell-scaffold constructs that mimic the cellular, biochemical and structural features of native AF tissue is critical.In this study, we fabricated aligned fibrous polyurethane scaffolds using an electrospinning technique and used them for culturing AF-derived stem/progenitor cells(AFSCs). Random fibrous scaffolds, also prepared via electrospinning, were used as a control. We compared the morphology, proliferation, gene expression and matrix production of AFSCs on aligned scaffolds and random scaffolds. There was no apparent difference in the attachment or proliferation of cells cultured on aligned scaffolds and random scaffolds. However, compared to cells on random scaffolds, the AFSCs on aligned scaffolds were more elongated and better aligned, and they exhibited higher gene expression and matrix production of collagen-I and aggrecan. The gene expression and protein production of collagen-II did not appear to differ between the two groups. Together, these findings indicate that aligned fibrous scaffolds may provide a favourable microenvironment for the differentiation of AFSCs into cells similar to outer AF cells, which predominantly produce collagen-I matrix. | Chen Liu Caihong Zhu Jun Li Pinghui Zhou Min Chen Huilin Yang Bin Li | 2015 | Bone Research2015，3，2： | 12 |
| 14 | New Early Cambrian Chordates from Haikou, Kunming显示文摘Two new chordates, Cathaymyrus haikouensis Luo et Hu sp. nov. andZhongxiniscus intermedius Luo et Hu gen. et sp. nov. are studied in this paper. Both display numerous S-shaped myomeres on their trunk. C. haikouensis shows a long and slim body similar to that of Cathaymyrus diadexus Shu et al., Zhongxiniscus approaches to Myllokunmingia and Haikouichthvs in the dorsal fin, but differs in the myomeres. Zhongxiniscus may be the intermediate form between Ca thaymyrus and Myllokunmingia and Haikouichthys. | LUO Huilin, HU Shixue and CHEN Liangzhong Yunnan Institute of Geological Sciences, 131 Baita Road, Kunming 650011, Yunnan | 2001 | Acta Geologica Sinica(English Edition)2001，75，4： | 12 |
| 15 | A review on hydraulic fracturing of unconventional reservoir显示文摘Hydraulic fracturing is widely accepted and applied to improve the gas recovery in unconventional reservoirs.Unconventional reservoirs to be addressed here are with very low permeability,complicated geological settings and in-situ stress field etc.All of these make the hydraulic fracturing process a challenging task.In order to effectively and economically recover gas from such reservoirs,the initiation and propagation of hydraulic fracturing in the heterogeneous fractured/porous media under such complicated conditions should be mastered.In this paper,some issues related to hydraulic fracturing have been reviewed,including the experimental study,field study and numerical simulation.Finally the existing problems that need to be solved on the subject of hydraulic fracturing have been proposed. | Quanshu Li Huilin Xing Jianjun Liu Xiangchon Liu | 2015 | Petroleum2015，1，1： | 11 |
| 16 | 吉林省德惠市土壤特性空间变异特征与格局显示文摘Based on regionalized variable theory, semivariograms of geo-statistics were used to research the spatial variation of soil properties quantitatively. The results showed that the semivariogram of soil organic matter is best described by spherical model, the best model for semivariograms of soil total N and available K is exponential models and that of available P belongs to linear with sill model. Those soil properties have different spatial correlations respectively, the lag of organic matter is the highest and that of available P is the lowest, the spatial correlation of N and available K belongs to moderate degree. Spatial heterogeneities are different too, the degree of organic matter and total N are higher, the degree of available K is in the next place and that of available P is the lowest. Influenced by the shape, topography and soil of the study area, all isotropies of available P are obvious in all directions while anisotropies of others are manifested. According to the analytical results, supported by GIS, Kriging and IDW methods are applied to describe and analyze the spatial distribution of soil properties. The results indicate that soil organic matter, total N and available K are distributed regularly from northeast to southwest, while available P is distributed randomly. | 李晓燕 张树文 王宗明 ZHANG Huilin | 2004 | Journal of Geographical Sciences2004，14，4： | 11 |
| 17 | The 30–60-day Intraseasonal Oscillations over the Subtropical Western North Pacific during the Summer of 1998显示文摘The features of 30–60-day convection oscillations over the subtropical western North Pacific(WNP) were investigated, along with the degree of tropical–subtropical linkage between the oscillations over the WNP during summer 1998. It was found that 30–60-day oscillations were extremely strong in that summer over both the subtropical and tropical WNP, providing a unique opportunity to study the behavior of subtropical oscillations and their relationship to tropical oscillations. Further analyses indicated that 30–60-day oscillations propagate westwards over the subtropical WNP and reach eastern China. In addition, 30–60-day oscillations in the subtropics are affected by those over the South China Sea(SCS) and tropical WNP through two mechanisms:(1) direct propagation from the tropics into the subtropics; and(2) a seesaw pattern between the tropics and subtropics, with the latter being predominant. | LU Riyu DONG Huilin SU Qin Hui DING | 2014 | Advances in Atmospheric Sciences2014，31，1： | 9 |
| 18 | 动力性心理治疗联合帕罗西汀对抑郁症的临床效果及心理状态分析显示文摘目的观察抑郁症应用帕罗西汀、动力性心理疗法联合治疗的效果。方法选取2017年7月-2018年7月在新乡医学院第二附属医院就诊的90例抑郁症患者临床资料,按不同治疗方案分两组,每组45例。对照组行帕罗西汀治疗,观察组在其基础上联合动力性心理治疗,比较两组疗效。结果观察组治疗总有效率高于对照组(P<0.05),观察组治疗后HADM评分比对照组低(P<0.05);观察组治疗后心理、生理、社会、环境评分均比对照组高(P<0.05)。结论抑郁症通过帕罗西汀、动力性心理疗法联合治疗后,抑郁心态明显改善,且生活质量提升,疗效显著。 | 张红胜 孙丽新 LI Huilin CHEN Zuoming | 2019 | 临床研究2019，27，11： | 8 |
| 19 | Decomposition and Evolution of Intracontinental Strike-Slip Faults in Eastern Tibetan Plateau显示文摘Little attention had been paid to the intracontinental strike-slip faults of the Tibetan Plateau. Since the discovery of the Longriba fault using re-measured GPS data in 2003, an increasing amount of attention has been paid to this neglected fault. The local relief and transverse swath profile show that the Longriba fault is the boundary line that separates the high and flat tomography of the Tibet plateau from the high and precipitous tomography of Orogen. In addition, GPS data shows that the Longriba fault is the boundary line where the migratory direction of the Bayan Har block changed from eastward to southeastward. The GPS data shows that the Longriba fault is the boundary fault of the sub-blocks of the eastern Bayan Har block. We built three-dimensional models containing the Longriba fault and the middle segment of the Longmenshan fault, across the Bayan Har block and the Sichuan Basin. A nonlinear finite element method was used to simulate the fault behavior and the block deformation of the Eastern Tibetan Plateau. The results show that the low resistivity and low velocity layer acts as a detachment layer, which causes the overlying blocks to move southeastward. The detachment layer also controls the vertical and horizontal deformation of the rigid Bayan Har block and leads to accumulation strain on the edge of the layer where the Longmenshan thrust is located. After a sufficient amount of strain has been accumulated on the Longmenshan fault, a large earthquake occurs, such as the 2008 Wenchuan earthquake. The strike slip activity of the Longriba fault, which is above the low resistivity and low velocity layer, partitions the lateral displacements of the Bayan Har block and adjusts the direction of motion of the Bayan Har block, from the eastward moving Ahba sub-block in the west to southeastward moving Longmenshan sub-block in the east. Four models with different depths to the Longriba fault were constructed: (1) a shallow fault with a depth of only 4 km, (2) a deeper fault that is half as deep as the Longmenshan fault, (3) a deep fault that is 2 km shallower than the low resistivity and low velocity layer, and (4) a fault that is as deep as the low resistivity and low velocity layer. The activity and influence of the Longriba fault with different development stage under this tectonic system were shown: in one Earthquake recurrence period, the rupture region of the fault increases with the depth of the fault, and the lateral slip partition by the fault also changes with the fault depth. It suggests that the Longriba fault is a newly generated fault that developed after the quick uplift in Late Cenozoic along this tectonic setting and gradually extended from the northwest to southeast. The calculations provide the characteristic of block deformation and fault behaviors of intra-continental strike-slip fault and major boundary thrust faults in the eastern margin of the Tibet plateau. Although the low resistivity and low velocity layer controls the deformation of the Bayan Har block and the uplift of the Longmenshan thrust, the partition of the Longriba fault has an important influence on the intra-plate deformation and modern geomorphic evolution. | YAO Qi XU Xiwei XING Huilin XU Chong WANG Xiaohui | 2013 | Acta Geologica Sinica(English Edition)2013，87，2： | 8 |
| 20 | YB-1, a new biomarker of glioma progression, is associated with the prognosis of glioma patients显示文摘(YB-1 ) Y 盒子蛋白质 1 是在各种各样的癌症表示的多功能的细胞的蛋白质,并且是在癌症治疗的一个潜在的目标。尽管有证据出现,那 YB-1 在人的癌症起一个作用,在 glioma 的 YB-1 表示的临床的意义没被建立。在现在的学习,我们在 glioma 肿瘤调查了 YB-1 水平并且分析了在 YB-1 水平和恶意的 glioma 的等级之间的关系,与提供为在临床、基本的研究背景的 gliomas 的诊断和治疗的新想法的目的。108 个病人的一个总数,与等级的 gliomas 包括 14, 31, 30,和 33 分别地,我, II, III,和 IV 在这研究被包括。YB-1 的 mRNA 和蛋白质层次被发现在等级 IV 和降低等级的肿瘤之间显著地不同。在脑髓的液体的 YB-1 层次比在等级在等级 III 和 IV glioma 病人是显著地更高的我和 II 病人。染色的 Immunofluorescence 被用来在细胞质和原子核检测 YB-1 的层次,并且结果显示细胞内部的分发显著地与 glioma 的病理学的等级被联系。YB-1 的高水平与弄短的幸存被联系,建议 YB-1 起在人的 glioma 的前进的一个作用。 | Jin Zheng Jiangwei Zhang Guangyue Li Huilin Gong | 2016 | Acta Biochimica et Biophysica Sinica2016，48，4： | 8 |
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