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| 1 | Orbit determination and time synchronization for a GEO/IGSO satellite navigation constellation with regional tracking network显示文摘Aiming at regional services,the space segment of COMPASS (Phase I) satellite navigation system is a constellation of Geostationary Earth Orbit (GEO),Inclined Geostationary Earth Orbit (IGSO) and Medium Earth Orbit (MEO) satellites.Precise orbit determination (POD) for the satellites is limited by the geographic distribution of regional tracking stations.Independent time synchronization (TS) system is developed to supplement the regional tracking network,and satellite clock errors and orbit data may be obtained by simultaneously processing both tracking data and TS data.Consequently,inconsistency between tracking system and TS system caused by remaining instrumental errors not calibrated may decrease navigation accuracy.On the other hand,POD for the mixed constellation of GEO/IGSO/MEO with the regional tracking network leads to parameter estimations that are highly correlated.Notorious example of correlation is found between GEO's orbital elements and its clock errors.We estimate orbital elements and clock errors for a 3GEO+2IGSO constellation in this study using a multi-satellite precise orbit determination (MPOD) strategy,with which clock error elimination algorithm is applied to separate orbital and clock estimates to improve numerical efficiency.Satellite Laser Ranging (SLR) data are used to evaluate User Ranging Error (URE),which is the orbital error projected on a receiver's line-of-sight direction.Two-way radio-wave time transfer measurements are used to evaluate clock errors.Experimenting with data from the regional tracking network,we conclude that the fitting of code data is better than 1 m in terms of Root-Mean-Square (RMS),and fitting of carrier phase is better than 1 cm.For orbital evaluation,difference between computed receiver-satellite ranging based on estimated orbits and SLR measurements is better than 1 m (RMS).For clock estimates evaluation,2-hour linear-fitting shows that the satellite clock rates are about 1.E-10 s/s,while receiver clock rates are about 1×10 13-1×10 12 s/s.For the 72-hour POD experiment,the average differences between POD satellite clock rates estimates and clock measurements based on TS system are about 1×10 13 s/s,and for receiver clock rates,the differences are about 1×10 15 s/s. | ZHOU ShanShi HU XiaoGong WU Bin LIU Li QU WeiJing GUO Rui HE Feng CAO YueLing Wu XiaoLi ZHU LingFeng SHI Xin TAN HongLi | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，6： | 44 |
| 2 | Photoactivated CRY1 and phyB Interact Directly with AUX/IAA Proteins to Inhibit Auxin Signaling in Arabidopsis显示文摘光是在 Arabidopsis 通过蓝色和调停 cryptochrome 的 red/far-red 光光敏电阻器和调停 phytochrome 的小径禁止胚轴房间延伸的关键环境暗示。相反,作为枢轴的内长的植物激素,植物生长素通过 AUX/IAA 蛋白质(AUX/IAAs ) 的植物生长素受体 TIR1/AFBs-mediated 降级支持胚轴延伸。然而,位于发信号的光和植物生长素的对抗相互作用下面的分子的机制仍然保持不清楚。这里,我们报导光禁止由 cryptochrome 的蓝、红的轻依赖者的相互作用通过 AUX/IAAs 的稳定发信号的植物生长素 1 (CRY1 ) 并且有 AUX/IAAs 的 phytochrome B 分别地。有 AUX/IAAs 的 CRY1 的蓝被触发光的相互作用与 AUX/IAAs 禁止 TIR1 的协会,导致这些蛋白质的导致植物生长素的降级的压抑。我们的结果显示光敏电阻器下游地直接作为一样与植物生长素受体分享 AUX/IAAs 表明部件。我们建议由光敏电阻器和植物生长素受体的 AUX/IAA 蛋白质稳定性的那条对抗规定允许植物平衡光和植物生长素信号优化他们的生长。 | Feng Xu Shengbo He Jingyi Zhang Zhilei Mao Wenxiu Wang Ting Li Jie Hua Shasha Du Pengbo Xu Ling Li Hongli Lian Hong-Quan Yang | 2018 | Molecular Plant2018，11，4： | 24 |
| 3 | Chemical characteristics of fine particles and their impact on visibility impairment in Shanghai based on a 1-year period observation显示文摘In this work, a one-year observation focusing on high time resolution characteristics of components in fine particles was conducted at an urban site in Shanghai. Contributions of different components on visibility impairment were also studied. Our research indicates that the major components of PM_(2.5) in Shanghai are water-soluble inorganic ions and carbonaceous aerosol, accounting for about 60% and 30% respectively. Higher concentrations of sulfate(SO42-) and organic carbon(OC) in PM_(2.5) occurred in fall and summer, while higher concentrations of nitrate(NO_3^-) were observed in winter and spring. The mass concentrations of Cl^- and K^+ were higher in winter. Moreover, NO_3^- increased significantly during PM_(2.5) pollution episodes. The high values observed for the sulfate oxidizing rate(SOR), nitrate oxidizing rate(NOR) and secondary organic carbon(SOC) in OC indicate that photochemical reactions were quite active in Shanghai. The IMPROVE(Interagency Monitoring of Protected Visual Environments) formula was used in this study to investigate the contributions of individual PM_(2.5) chemical components to the light extinction efficient in Shanghai. Both NH_4NO_3 and(NH_4)_2SO_4 had close relationships with visibility impairment in Shanghai. Our results show that the reduction of anthropogenic SO_2, NO_x and NH_3 would have a significant effect on the improvement of air quality and visibility in Shanghai. | Min Zhou Liping Qiao Shuhui Zhu Li Li Shengrong Lou Hongli Wang Qian Wang Shikang Tao Cheng Huang Changhong Chen | 2016 | Journal of Environmental Sciences2016，28，10： | 22 |
| 4 | Management of cytokine release syndrome related to CAR-T cell therapy显示文摘Chimeric antigen receptor T (CAR-T) cell therapy is a novel cellular immunotherapy that is widely used to treat hematological malignancies, including acute leukemia, lymphoma, and multiple myeloma. Despite its remarkable clinical effects, this therapy has side effects that cannot be underestimated. Cytokine release syndrome (CRS) is one of the most clinically important and potentially life-threatening toxicities. This syndrome is a systemic immune storm that involves the mass cytokines releasing by activated immune cells. This phenomenon causes multisystem damages and sometimes even death. In this study, we reported the management of a patient with recurrent and refractory multiple myeloma and three patients with acute lymphocytic leukemia who suffered CRS during CAR-T treatment. The early application of tocilizumab, an anti-IL-6 receptor antibody, according to toxicity grading and clinical manifestation is recommended especially for patients who suffer continuous hyperpyrexia, hypotensive shock, acute respiratory failure, and whose CRS toxicities deteriorated rapidly. Moreover, low doses of dexamethasone (5-10 mg/day) were used for refractory CRS not responding to tocilizumab. The effective management of the toxicities associated with CRS will bring additional survival opportunities and improve the quality of life for patients with cancer. | Hongli Chen Fangxia Wang Pengyu Zhang Yilin Zhang Yinxia Chen Xiaohu Fan Xingmei Cao Jie Liu Yun Yang Baiyan Wang Bo Lei Liufang Gu Ju Bai Lili Wei Ruili Zhang Qiuchuan Zhuang Wanggang Zhang Wanhong Zhao Aili He | 2019 | Frontiers of Medicine2019，13，5： | 21 |
| 5 | A step metallogenetic model for gold deposits in the northwestern Shandong Peninsula, China显示文摘Based on our study of the nature and variation of mineralization-controlling faults in their deep extension and the spatial distribution of gold orebodies in the northwestern Shandong Peninsula (NSP), here we propose that the gold deposits in the Jiaojia gold belt are controlled by listric faults and the gold deposits in the NSP are controlled by extensional fault system. We also suggest that there is a multiple mineralization space in the deep part of the NSP gold belt. As steps or benches occur along the deep extention of the listric fault where its dipping angle changes from steep to gentle, a number of gold deposits are correspondingly distributed as a steplike pattern, which is named as a step metallogenetic model for gold deposits in the NSP. The gold deposits in Shandong Peninsula were formed in the Cretaceous when the crust in the region experienced extention and thinning following the strong collision between North China Plate and Yangtze Plate during the Triassic. Crust anataxis, fluid remobilization, and extention-detachement of the crust are the leading factors for the gold mineralization. | SONG MingChun YI PiHou XU JunXiang CUI ShuXue SHEN Kun JIANG HongLi YUAN WenHua WANG HuaJiang | 2012 | Science China Earth Sciences2012，55，6： | 21 |
| 6 | ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer显示文摘 | Shunrong Ji Yi Qin Si Shi Xiangyuan Liu Hongli HU Hu Zhou Jing Gao Bo Zhang Wenyan Xu Jiang Liu Dingkong Liang Liang Liu Chen Liu Jiang Long Haijun Zhou Paul J Chiao Jin Xu Quanxing Ni Daming Gao Xianjun Yu | 2015 | Cell Research2015，25，5： | 19 |
| 7 | Ozone sensitivity analysis with the MM5-CMAQ modeling system for Shanghai显示文摘Ozone has become one of the most important air pollution issues around the world. This article applied both O 3 /(NOy-NOx) and H 2 O 2 /HNO 3 indicators to analyze the ozone sensitivity in urban and rural areas of Shanghai, with implementation of the MM5-CMAQ modeling system in July, 2007. The meteorological parameters were obtained by using the MM5 model. A regional emission inventory with spatial and temporal allocation based on the statistical data has been developed to provide input emission data to the MM5-CMAQ modeling system. Results showed that the ozone concentrations in Shanghai show clear regional differences. The ozone concentration in rural areas was much higher than that in the urban area. Two indicators showed that ozone was more sensitive to VOCs in urban areas, while it tended to be NOx sensitive in rural areas of Shanghai. | Li Li Changhong Chen Cheng Huang Haiying Huang Gangfeng Zhang Yangjun Wang Minghua Chen Hongli Wang Yiran Chen D. G. Streets Jiamo Fu | 2011 | Journal of Environmental Sciences2011，23，7： | 18 |
| 8 | Transportation characteristics of δ^(13)C in the plants-soil-bedrock-cave system in Chongqing karst area显示文摘Here we use an analytical method to determine δ13C in local plants and organic matter in the soils above Furong cave,Chongqing,China.We also monitored δ13C in dissolved inorganic carbon(DIC) of drip water,δ13C of active deposits under the drip waters,and the concentration of air CO2(PCO2).Based on these,we preliminarily studied the transportation characteristics of stable carbon isotope(13C) in cave system of the subtropical karst area.The average δ13C value of 27 local plant samples,which belong to 16 families,was -32‰ and the weighted δ13C for surface dry biomass was -33‰.We found that for 54 soil samples collected from 5 soil profiles,δ13C of soil organic matters was -22‰,which could be attributed to the different transportation rates of stable carbon isotopes during the decomposition of plants and organic matters in soils.The relatively lighter 12C tended to transfer into gaseous CO2,which made the relatively heavier 13C concentrated in the soils.On the basis of monitoring of DIC-δ13C in drip waters from July 2009 to June 2010,we found that values in winter months were heavier and values in summer months were lighter in general,the reason of which was that in summer months,both the temperature and the humidity were comparatively higher,resulted in more CO2 with lighter δ13C generated from organic matters decomposition and plants respiration.The average DIC -δ13C value was -11‰,about 11‰ heavier than the δ13C of organic matters in soils,which proved that part of DIC in cave drip water was sourced from dissolution of inorganic carbonate(host rock,with heavier δ13C).As for the δ13C of active deposits at five drip water sites in Furong cave,they had almost the same variation with relatively light values.In other words,these active speleothems were deposited at equilibrium conditions for isotopic fractionation.These results suggest that the carbon isotopic information of speleothems could be used to track the evolution of local vegetation in certain situations. | Li TingYong Li HongChun Xiang XiaoJing Kuo Tz-Shing Li JunYun Zhou FuLi Chen HongLi Peng LingLi | 2012 | Science China Earth Sciences2012，55，4： | 18 |
| 9 | Chemical and optical properties of aerosols and their interrelationship in winter in the megacity Shanghai of China显示文摘A field campaign on air quality was carried out in Shanghai in winter of 2012. The concentrations of NO, NO2, NOx, SO2, CO, and PM2.5increased during haze formation. The average masses of SO42-, NO3-and NH4+were 10.3, 11.7 and 6.7 μg/m3 during the haze episodes, which exceeded the average(9.2, 7.9, and 3.4 μg/m3) of these components in the non-haze days. The mean values for the aerosol scattering coefficient(b sp), aerosol absorption coefficient(b ap) and single scattering albedo(SSA) were 288.7, 27.7 and0.91 Mm-1, respectively. A bi-peak distribution was observed for the mass concentrations of CO, NO, NO2, and NOx. More sulfate was produced during daytime than that in the evening due to photochemical reactions. The mass concentration of NH4+achieved a small peak at noontime. NO3-showed lower concentrations in the afternoon and higher concentrations in the early morning. There were obvious bi-peak diurnal patterns for b sp and b ap as well as SSA. b sp and b ap showed a positive correlation with PM2.5mass concentration.(NH4)2SO4, NH4NO3, organic mass, elemental carbon and coarse mass accounted for 21.7%, 19.3%, 31.0%, 9.3% and 12.3% of the total extinction coefficient during non-haze days, and 25.6%, 24.3%, 30.1%, 8.1% and 8.2% during hazy days. Organic matter was the largest contributor to light extinction. The contribution proportions of ammonium sulfate and ammonium nitrate to light extinction were significantly higher during the hazy time than during the non-haze days. | Tingting Han Liping Qiao Min Zhou Yu Qu Jianfei Du Xingang Liu Shengrong Lou Changhong Chen Hongli Wang Fang Zhang Qing Yu Qiong Wu | 2015 | Journal of Environmental Sciences2015，27，1： | 14 |
| 10 | Induction of systemic lupus erythematosus syndrome in BALB/c mice by immunization with active chromatin显示文摘AIM: To establish an animal model for systemic lupus erythematosus (SLE)-like syndrome in mice. METHODS: BALB/c mice were immunized with active chromatin isolated from ConA-actived syngeneic spleno-lymphocytes. Plasma samples of mice were tested by enzyme-linked immunosorbent assays (ELISA) for the presence of IgG anti-dsDNA, -ssDNA, and anti-histone antibodies. Tumor necrosis factor-α (TNF-α) in serum was measured by ELISA. Spleno-lymphocyte proliferation assays and the levels of interferon-γ (IFN-γ) in supernatants were tested respectively. Proteinuria was measured. Kidneys were examined by direct immunohistochemical method and light microscopy. RESULTS: Anti-ds DNA, ssDNA, and histone antibodies were induced in active chromatin-immu- nized mice, the proliferation response of splenocytes to ConA and LPS were reduced, levels of interferon-γ in supernatants and TNF-α in serum were lowered. Lupus nephritis was assessed by the presence of Ig deposits, glomerular pathology and proteinuria. CONCLUSION: The active chromatin-induced SLE-like mouse model was similar to idiopathic SLE in human. | HongLI Yun-yiZHANG Ya-nanSUN Xi-yiHUANG Yong-fengJIA DuanLI | 2004 | Acta Pharmacologica Sinica2004，25，6： | 13 |
| 11 | MiR-122-5p suppresses the proliferation, migration, and invasion of gastric cancer cells by targeting LYN显示文摘Gastric cancer(GC)is one of malignant tumors with high mortality and morbidity in the world.MicroRNA-122(miR-122)acts as a tumor suppressor in a variety of cancers and has been found to be dominant in gastric adenocarcinoma.However,the specific biological function of miR-122-5p in GC is not completely clear.In this study,we found that miR-122-5p was low-expressed in GC tissues and cell lines by using qRT-PCR.Overexpression of miR-122-5p inhibited the proliferation,migration,and invasion of GC cells by using CCK-8 and transwell assays.On the contrary,downregulation of miR-122-5p promoted the proliferation,migration,and invasion of GC cells.In addition,we found that the expression of LYN,an Src family tyrosine kinase,was inversely correlated with miR-122-5p expression in GC tissues by using western blot analysis,immunohistochemistry,and qRT-PCR assays.Meanwhile,luciferase assay results indicated that LYN is a direct target of miR-122-5p in GC cells.Moreover,silencing LYN expression by its siRNA inhibited the proliferation,migration,and invasion of GC cells.Importantly,overexpression of LYN restored miR-122-5p-mediated inhibition of the proliferation,migration,and invasion of GC cells.Taken together,our results indicated miR-122-5p inhibited the proliferation,migration,and invasion by targeting LYN in GC. | Lei Meng Zhangming Chen Zhe Jiang Ting Huang Jie Hu Panquan Luo Hongli Zhang Mengqi Huang Lei Huang Yu Chen Ming Lu A-man Xu Songcheng Ying | 2020 | Acta Biochimica et Biophysica Sinica2020，52，1： | 12 |
| 12 | Liquid bridge force between two unequal-sized spheres or a sphere and a plane显示文摘Liquid bridge force acting between wet particles is an important property in particle characterization. This paper deals with liquid bridge force between either two unequal-sized spherical particles or a sphere and a flat plate under conditions where gravitational effect arising from bridge distortion is negligible. In order to calculate the force of the liquid bridge efflciently and accurately, expressions of liquid conflguration and liquid bridge force were derived by building a mechanical model, which assumes the liquid bridge to be circular in shape between either two unequal-sized spheres or a sphere and a plane. To assess the accuracy of the numerical results of the calculated liquid bridge forces, they were compared to the published experimental data. | Youchuan Chen Yongzhi Zhao Hongli Gao Jinyang Zheng | 2011 | Particuology2011，9，4： | 11 |
| 13 | Estimation of ground heat flux and its impact on the surface energy budget for a semi-arid grassland显示文摘Three approaches,i.e.,the harmonic analysis(HA) technique,the thermal diffusion equation and correction(TDEC) method,and the calorimetric method used to estimate ground heat flux,are evaluated by using observations from the Semi-Arid Climate and Environment Observatory of Lanzhou University(SACOL) in July,2008.The calorimetric method,which involves soil heat flux measurement with an HFP01SC self-calibrating heat flux plate buried at a depth of 5 cm and heat storage in the soil between the plate and the surface,is here called the ITHP approach.The results show good linear relationships between the soil heat fluxes measured with the HFP01SC heat flux plate and those calculated with the HA technique and the TDEC method,respectively,at a depth of 5 cm.The soil heat fluxes calculated with the latter two methods well follow the phase measured with the HFP01SC heat flux plate.The magnitudes of the soil heat flux calculated with the HA technique and the TDEC method are close to each other,and they are about 2 percent and 6 percent larger than the measured soil heat flux,respectively,which mainly occur during the nighttime.Moreover,the ground heat fluxes calculated with the TDEC method and the HA technique are highly correlated with each other(R2 = 0.97),and their difference is only about 1 percent.The TDEC-calculated ground heat flux also has a good linear relationship with the ITHP-calculated ground heat flux(R2 = 0.99),but their difference is larger(about 9 percent).Furthermore,compared to the HFP01SC direct measurements at a depth of 5 cm,the ground heat flux calculated with the HA technique,the TDEC method,and the ITHP approach can improve the surface energy budget closure by about 6 percent,7 percent,and 6 percent at SACOL site,respectively.Therefore,the contribution of ground heat flux to the surface energy budget is very important for the semi-arid grassland over the Loess Plateau in China.Using turbulent heat fluxes with common corrections,soil heat storage be-tween the surface and the heat flux plate can improve the surface energy budget closure by about 6 to 7 percent,resulting in a clo-sure of 82 to 83 percent at the SACOL site. | JinQing Zuo JieMin Wang JianPing Huang WeiJing Li GuoYin Wang HongLi Ren | 2011 | Research in Cold and Arid Regions2011，3，1： | 11 |
| 14 | Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer显示文摘胃的癌症是世界范围的最普通的恶意之一;然而,在 tumorigenesis 的分子的机制仍然需要探索。BCL2L11 属于 BCL-2 家庭,并且充当内在的 apoptotic 串联的一个中央管理者并且调停房间 apoptosis。尽管 miRNAs 被报导了涉及癌症开发的每个阶段,在 GC 的 miR-24 的角色还没被报导。在现在的学习,当 BCL2L11 的表示在 GC 的肿瘤纸巾被禁止时, miR-24 被发现起来调整。研究从在 vitro 并且在显示出的 vivo,那 miR-24 调整 BCL2L11 表示由与 mRNA 的 3UTR 直接有约束力,因此支持房间生长,移植当禁止房间 apoptosis 时。因此, miR-24 是能是为未来的潜在的药目标的新奇 onco-miRNA 临床的使用。 | Haiyang Zhang Jingjing Duan Yanjun Qu Ting Deng Rui Liu Le Zhang Ming Bai Jialu Li Tao Ning Shaohua Ge Xia Wang ZhenzhenWang~ Qian Fan Hongli Li Guoguang Ying Dingzhi Huang Yi Ba | 2016 | Protein & Cell2016，7，2： | 11 |
| 15 | High precision topographic data on Lop Nor basin's Lake 'Great Ear' ? and the timing of its becoming a dry salt lake显示文摘High precision elevation measurements using DGPS were carried out along three representative tran- sects for the 'Great Ear' area, a dry salt lake within the Lop Nor basin. Results indicate that the Lop Nor basin is only 5.2 m deep and its lowest point occurs at the center of the 'Great Ear'. In addition, the basin is asymmetric - steeper in the southwest (0.19‰) and gentler in the northeast (0.09‰). Points along the same 'Great Ear' ring were found to have an identical elevation value, but different when from different ones (lower towards the center). The spacing of the 'Great Ear' rings was found to be closely related with the surface steepness. The closer the 'Great Ear' rings are spaced, the steeper the ground surface, and vice versa. These findings support the argument that the 'Great Ear' rings are the former shoreline trails left behind by Lop Nor water during the last few episodes of recession towards its total dry up. A comprehensive analysis of the high precision elevation data, historical accounts, aerial and satellite photographs and imagery, and official topographic maps of the study area suggests that the 'Great Ear' area in the Lop Nor basin was incorrectly mapped as being covered by a great body of water on the 1963 topographic maps. A re-interpretation of the 1958 aerial photographs and newer remote sensing imagery indicated that the 'Great Ear' ring structure was already in place in 1958 and it continued to appear on the subsequent remote sensing data without any major changes. It is estimated that lake water in the 'Great Ear' area of the Lop Nor basin disappeared between the late 1930s and early 1940s. | LI BaoGuo MA LiChun JIANG PingAn DUAN ZengQiang SUN DanFeng QIU HongLie ZHONG JunPing WU HongQi | 2008 | Chinese Science Bulletin2008，53，6： | 11 |
| 16 | NASICON-structured Na3.1Zr1.95Mg0.05Si2PO12 solid electrolyte for solid-state sodium batteries显示文摘Using stable inorganic solid electrolyte to replace organic liquid electrolyte could significantly reduce potential safety risks of rechargeable batteries. Na-superionic conductor(NASICON)-structured solid electrolyte is one of the most promising sodium solid electrolytes and can be employed in solid-state sodium batteries. In this work, a NASICONstructured solid electrolyte Na_(3.1)Zr_(1.95)Mg_(0.05)Si_2PO_(12) was synthesized through a facile solid-state reaction, yielding high sodium-ionic conductivity of 1.33×10^(-3) S·cm^(-1) at room temperature. The results indicate that Mg^(2+)is a suitable and economical substitution ion to replace Zr^(4+), and this synthesis route can be scaled up for powder preparation with low cost. In addition to electrolyte material preparation, solid-state batteries with Na_(3.1)Zr_(1.95)Mg_(0.05)Si_2PO_(12) as electrolyte were assembled. A specific capacity of 57.9 mAh·g^(-1) is maintained after 100 cycles under a current density of 0.5 C rate at room temperature. The favorable cycling performance of the solid-state battery suggests that Na_(3.1)Zr_(1.95)Mg_(0.05)Si_2PO_(12) is an ideal electrolyte candidate for solid-state sodium batteries. | Jing Yang HongLi Wan ZhiHua Zhang GaoZhan Liu XiaoXiong Xu YongSheng Hu Xia-Yin Yao | 2018 | Rare Metals2018，37，6： | 10 |
| 17 | Sedimentary Response of Different Fan Types to the Paleogene-Neogene Basin Transformation in the Kuqa Depression,Tarim Basin,Xinjiang Province显示文摘A group of alluvial fans formed in the early Paleogene represent marginal sedimentary facies at the foot of the South Tianshan Mountain,Kuqa Depression,Tarim Basin,Xinjiang province. Two types of fans occurred in the middle-late Paleogene Kumugeliemu and Suweiyi formations:one alluvial,and the other fan delta deposited in a lacustrine setting.Within the early Neogene Jidike Formation,coastal subaqueous fans developed,probably in a deeper water lacustrine setting.The three types of fans are stacked vertically in outcrop with the sequence in ascending order:bottom alluvial,middle fan-delta,and top subaqueous.The subaqueous is a typical coarse-fan deposit occurring in the glutinite member of the Jidike Formation in some wells.Laterally,from the foreland to the lacustrine settings,the distribution pattern of sedimentary facies represents the same three fan types sequentially.The spatial distribution of these fans was controlled by the Paleogene-Neogene Basin transformation,and evolution with different types of fans developed in the Kuqa Depression in response.In the Paleogene,the Kuqa Depression was a rift basin where an alluvial fan was deposited in the foreland setting,which,by early Neogene,became a foreland basin when the lake level changed. With any rise in lake level,fan-deltas migrated from lacustrine to foreland settings,whereas when the lake level fell,fan migration was reversed.In the early Neogene,with increasing slope and rising lake level,fans progressed and covered the previous fan-delta and lacustrine mudstone.Eventually, subaqueous fans developed,forming the present spatial configuration of these three fan types. | GAO Zhiyong GUO Hongli ZHU Rukai ZHANG Lijuan SUN Yushan | 2009 | Acta Geologica Sinica(English Edition)2009，83，2： | 10 |
| 18 | Photoexcited CRYPTOCHROME 1 Interacts Directly with G-Protein 13 Subunit AGB1 to Regulate the DNA-Binding Activity of HY5 and Photomorphogenesis in Arabidopsis显示文摘 | Hongli Lian Pengbo Xu Shengbo He Jun Wu Jian Pan Wenxiu Wang Feng Xu Sheng Wang Junsong Pan Jirong Huang Hong-Quan Yang | 2018 | Molecular Plant2018，11，10： | 10 |
| 19 | Nitrogen Biological Cycle Characteristics of Seepweed(Suaeda salsa) Wetland in Intertidal Zone of Huanghe(Yellow) River Estuary显示文摘From April 2008 to November 2009,the nitrogen(N) cycle of plantsoil system in seepweed(Suaeda salsa) wetland in the intertidal zone of the Huanghe(Yellow) River estuary was studied.Results showed that soil N had sig-nificant seasonal fluctuations and vertical distribution,and the net N mineralization rates in topsoil were significantly different in growing season(p < 0.01).The N/P ratio(9.87 ± 1.23) of S.salsa was less than 14,indicating that plant growth was limited by N.The N accumulated in S.salsa litter at all times during decomposition,which was ascribed to the N immobilization by microbes from the environment.Soil organic N was the main N stock of plant-soil system,accounting for 97.35% of the total N stock.The N absorption and utilization coefficients of S.salsa were very low(0.0145 and 0.3844,respectively),while the N cycle coefficient was high(0.7108).The results of the N turnovers among compartments of S.salsa wetland showed that the N uptake amount of aboveground part and root were 7.764 g/m2and 4.332 g/m2,respectively.The N translocation amounts from aboveground part to root and from root to soil were 3.881 g/m2 and 0.626 g/m2,respectively.The N translocation amount from aboveground living body to litter was 3.883 g/m2,the annual N return amount from litter to soil was more than 0.125(-) g/m2(minus represented immobilization),and the net N mineralization amount in topsoil(0-15 cm) in growing season was 1.190 g/m2.The assessment of N biological cycle status of S.salsa wetland indicated that N was a very important limiting factor and the ecosystem was situated in unstable and vulnerable status.The S.salsa was seemingly well adapted to the low-nutrient status and vulnerable habitat,and the N quantitative relationships determined in the compartment model might provide scientific base for us to reveal the special adaptive strategy of S.salsa to the vulnerable habitat in the following studies. | SUN Zhigao MOU Xiaojie SUN Jingkuan SONG Hongli YU Xiang WANG Lingling JIANG Huanhuan SUN Wanlong SUN Wenguang | 2012 | Chinese Geographical Science2012，22，1： | 9 |
| 20 | MicroRNAs in idiopathic pulmonary fibrosis: involvement in pathogenesis and potential use in diagnosis and therapeutics显示文摘MicroRNAs(miRNAs) are a class of phylogenetically conserved, non-coding short RNAs,19–22 nt in length which suppress protein expression through base-pairing with the 30-untranslated region of target m RNAs. mi RNAs have been found to participate in cell proliferation, differentiation and apoptosis. Idiopathic pulmonary fibrosis(IPF) is a chronic, progressive, and high lethality fibrotic lung disease for which currently there is no effective treatment. Some mi RNAs have been reported to be involved in the pathogenesis of pulmonary fibrosis. In this review, we discuss the role of mi RNAs in the pathogenesis, diagnosis and treatment of IPF. | Huimin Li Xiaoguang Zhao Hongli Shan Haihai Liang | 2016 | Acta Pharmaceutica Sinica B2016，6，6： | 9 |
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