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| 1 | Maximum standardized uptake value on PET/CT in preoperative assessment of lymph node metastasis from thoracic esophageal squamous cell carcinoma显示文摘The presence of lymph node metastasis is an important prognostic factor for patients with esophageal cancer.Accurate assessment of lymph nodes in thoracic esophageal carcinoma is essential for selecting appropriate treatment and forecasting disease progression.Positron emission tomography combined with computed tomography(PET/CT)is becoming an important tool in the workup of esophageal carcinoma.Here,we evaluated the effectiveness of the maximum standardized uptake value(SUVmax)in assessing lymph node metastasis in esophageal squamous cell carcinoma(ESCC)prior to surgery.Fifty-nine surgical patients with pathologically confirmed thoracic ESCC were retrospectively studied.These patients underwent radical esophagectomy with pathologic evaluation of lymph nodes.They all had18F-FDG PET/CT scans in their preoperative staging procedures.None had a prior history of cancer.The pathologic status and PET/CT SUVmax of lymph nodes were collected to calculate the receiver operating characteristic(ROC)curve and to determine the best cutoff value of the PET/CT SUVmax to distinguish benign from malignant lymph nodes.Lymph node data from 27 others were used for the validation.A total of 323 lymph nodes including 39 metastatic lymph nodes were evaluated in the training cohort,and 117lymph nodes including 32 metastatic lymph nodes were evaluated in the validation cohort.The cutoff point of the SUVmax for lymph nodes was 4.1,as calculated by ROC curve(sensitivity,80%;specificity,92%;accuracy,90%).When this cutoff value was applied to the validation cohort,a sensitivity,a specificity,and an accuracy of 81%,88%,and 86%,respectively,were obtained.These results suggest that the SUVmax of lymph nodes predicts malignancy.Indeed,when an SUVmax of 4.1 was used instead of 2.5,FDG-PET/CT was more accurate in assessing nodal metastasis. | Amos JM Ela Bella Ya-Rui Zhang Wei Fan Kong-Jia Luo Tie-Hua Rong Peng Lin Hong Yang Jian-Hua Fu | 2014 | Chinese Journal of Cancer2014，33，4： | 3 |
| 2 | Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through mitochondrial/caspases pathway显示文摘 | Eom KS Hong JM Youn MJ | 2008 | Biol Pharm Bull2008，31，： | 1 |
| 3 | Kyphoplasty enhances function and structural alignment in multiple myeloma显示文摘 | Lane JM Hong R Koob J | 2004 | Clin Orthop2004，42，6： | 1 |
| 4 | Prediction of progressive motor deficits in patients with deep subcortical infarction 显示文摘 | Kim SK Song P Hong JM | 2008 | Cerehbrovasc Dis2008，25，4： | 1 |
| 5 | A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke显示文摘 | Lee JS Hong JM Moon GJ | 2010 | Stem Cells2010，28，6： | 1 |
| 6 | Vertebral artery dominance contributes to basilar artery curvature and peri-vertebrobasilar junctional infarcts显示文摘 | Hong JM Chung CS Bang OY | 2009 | Neurol Neurosurg Psychchiatry2009，80，10： | 1 |
| 7 | Prospective study of the incidence and outcome of intra-abdominal hypertension and the abdominal compartment syndrome显示文摘 | Hong JJ Cohn SM Perez JM | 2002 | Br J Surg2002，89，5： | 1 |
| 8 | Prediction of progressive motor deficits in patients with deep subcortical infarction显示文摘 | Kim SK Song P Hong JM | 2008 | Cerebrovasc Dis2008，25，3： | 1 |
| 9 | Patterns of fail- ure in supratentorial primitive neuroeetodermal tumors trea- ted in Children~ Cancer Group Study 921, a phase ]H com- bined modality study 显示文摘 | HONG TS MEHTA MP BOYETT JM | 2004 | Int J Radiat Oneol Biol Phys2004，60，1： | 1 |
| 10 | Promoter polymorphisms of the vascular endothelial growth factor gene is associated with an osteonecrosis of the femoral head in the Korean population 显示文摘 | Kim TH Hong JM Lee JY | 2007 | Osteoarthritis Cartilage2007，14，： | 1 |
| 11 | Heterogeneous characteristics of Korean patients with dysferlinopathy 显示文摘 | Park HJ Hong JM Suh GI | 2012 | J Korean Med Sci2012，27，4： | 1 |
| 12 | Association study of hypoxia inducible factor 1alpha(HIF1alpha) with osteonecrosis of femoral head in a Korean population显示文摘 | Hong JM Kim TH Chae SC | 2007 | Osteoarthritis Cartilage2007，15，： | 1 |
| 13 | A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke显示文摘 | Lee JS Hong JM Moon GJ | 2010 | Stem Cells2010，28，6： | 1 |
| 14 | Chronic vitamin C insufficiency aggravated thioacetamide-induced liver fibrosis in gulo-knockout mice显示文摘 | Kim JH Jeong YJ Hong JM | 2013 | Free Radic Biol Med2013，5849，： | 1 |
| 15 | Apatinib (YN968DI) Reverses Multidrug Resistance by Inhibiting the Efflux Function of Multiple ATP-Binding Cassette Transporters 显示文摘 | Yah JM Yong JL Hong BH | 2010 | Cancer Res2010，70，20： | 1 |
| 16 | Conventional enhancement CT: a valuable tool for evaluating pial collateral flow in acute ischemic stroke显示文摘 | Choi JY Kim EJ Hong JM | 2011 | Cerebrovasc Dis2011，31，： | 1 |
| 17 | prediction of progressive motor deficits in patients with deep subcortical infarction显示文摘 | Kim SK Song P Hong JM | | 0，，： | 1 |
| 18 | Microembolic signals in a- cute posterior circulation cerebral ischemia sources and conse- quences显示文摘 | Hwang J Kim SJ Hong JM | 2012 | Stroke2012，43，3： | 1 |
| 19 | Ischemic stroke in cancer patients with and without conventional mechanisms:a multicenter study in Korea显示文摘 | Kim SG Hong JM Kim HY | 2010 | Stroke2010，41，1： | 1 |
| 20 | Prospective study of the incidence and outcome of intra-abdominal hypertension and the abdominal compartment syndrome显示文摘 | Hong JJ Cohn SM Perez JM | 2002 | Br J Surg2002，19，5： | 1 |
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