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| 1 | RosBREED:bridging the chasm between discovery and application to enable DNA-informed breeding in rosaceous crops显示文摘The Rosaceae crop family(including almond,apple,apricot,blackberry,peach,pear,plum,raspberry,rose,strawberry,sweet cherry,and sour cherry)provides vital contributions to human well-being and is economically significant across the U.S.In 2003,industry stakeholder initiatives prioritized the utilization of genomics,genetics,and breeding to develop new cultivars exhibiting both disease resistance and superior horticultural quality.However,rosaceous crop breeders lacked certain knowledge and tools to fully implement DNA-informed breeding—a“chasm”existed between existing genomics and genetic information and the application of this knowledge in breeding.The RosBREED project(“Ros”signifying a Rosaceae genomics,genetics,and breeding community initiative,and“BREED”,indicating the core focus on breeding programs),addressed this challenge through a comprehensive and coordinated 10-year effort funded by the USDA-NIFA Specialty Crop Research Initiative.RosBREED was designed to enable the routine application of modern genomics and genetics technologies in U.S.rosaceous crop breeding programs,thereby enhancing their efficiency and effectiveness in delivering cultivars with producer-required disease resistances and market-essential horticultural quality.This review presents a synopsis of the approach,deliverables,and impacts of RosBREED,highlighting synergistic global collaborations and future needs.Enabling technologies and tools developed are described,including genome-wide scanning platforms and DNA diagnostic tests.Examples of DNA-informed breeding use by project participants are presented for all breeding stages,including pre-breeding for disease resistance,parental and seedling selection,and elite selection advancement.The chasm is now bridged,accelerating rosaceous crop genetic improvement. | Amy F.Iezzoni Jim McFerson James Luby Ksenija Gasic Vance Whitaker Nahla Bassil Chengyan Yue Karina Gallardo Vicki McCracken Michael Coe Craig Hardner Jason D.Zurn Stan Hokanson Eric van de Weg Sook Jung Dorrie Main Cassia da Silva Linge Stijn Vanderzande Thomas M.Davis Lise L.Mahoney Chad Finn Cameron Peace | 2020 | Horticulture Research2020，7，1： | 2 |
| 2 | 面向教学设计的教学方法新分类显示文摘依据问题的呈方式现、复杂性程度和来源,本文提出了面向教学设计的教学方法分类学。这一富有启发性的理论框架将教学方法分为五个层次:接受、运用、扩展、创见和质疑,从而有希望改变教学仅仅限于传递信息的状况,为培养高层次思维能力和问题解决能力服务。 | Brad Hokanson Simon Hooper 王耐 盛群力 | 2005 | 远程教育杂志2005，23，2： | 2 |
| 3 | Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level:a meta-analy-sis of population-based prospective studies显示文摘 | Hokanson J E Austin M A | 1996 | J Card-iovasc Risk1996，3，： | 1 |
| 4 | Strawberry genbank-de- rived and genomic simple sequence repeats (SSR)markers and their utility with strawberry, blakberry, and red and black raspber- ry显示文摘 | Lewers K S Styan S M N Hokanson S C | 2005 | J Amer Soc Hort Sci2005，130，1： | 1 |
| 5 | Plasma trigyceride levelisa risk factor for cardiovascular clisease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies显示文摘 | Hokanson JE AustinMA | | 0，，： | 1 |
| 6 | A virologicpilot study of valacyclovir in infectious mononucleosis 显示文摘 | Balfour HH Hokanson KM Schacherer RM | 2007 | J ClinVirol2007，39，1： | 1 |
| 7 | Creativity in the training and practice of instructional designers:the design/creativity loops model 显示文摘 | Gregory Clinton Brad Hokanson | 2011 | Educational Technology Research and Development2011，，： | 1 |
| 8 | Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analysis of population-based prospective studies显示文摘 | Hokanson JE Austin MA | 1996 | J Cardiovasc Risk1996，3，2： | 1 |
| 9 | The complex role oftriglycerides in cardiovascular disease显示文摘 | Abdel-Maksoud MF Hokanson JE | | SEMINARS IN VASCULAR MEDICINE0，，： | 1 |
| 10 | Characterization of low- density lipoprotein subclasses: methodologic approaches and clini- cal relevance 显示文摘 | Austin MA Hokanson JE Brunze}l JD | 1994 | Curt Opin Lipidol1994，5，6： | 1 |
| 11 | Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level:a meta-analysis of population-based prospective studies显示文摘 | Hokanson JE Austin MA | 1996 | J Cardiovasc Risk1996，3，2： | 1 |
| 12 | The complex role of tri-glycerides in cardiovascular disease 显示文摘 | Abdel Maksoud M F Hokanson J E | 2002 | Semin Vase Med2002，2，： | 1 |
| 13 | Mic- rosatellite(SSR) markers reveal genetic identities, genetic diversity and relationships in a Malus × domestica Borkh core subset collection 显示文摘 | HOKANSON S C SZEWC-MCFAI)DEN A K LAMBOY W F | 1998 | Theor Appl Genet1998，97，： | 1 |
| 14 | Microsatellite (SSR) markers reveal genetic identities, genetic diversity and relationships in a Malus×domestica borkh. core subset collection显示文摘 | S. C. Hokanson A. K. Szewc-McFadden W. F. Lamboy J. R. McFerson | 1998 | TAG Theoretical and Applied Genetics (-)1998，，5： | 1 |
| 15 | Evaluating UV/H2O2 processes for methyl tert-butyl ether and tertiary butyl alcohol removal:Effect of pretreatment options and light sources显示文摘 | Li K Hokanson D R Crittenden J C | 2008 | Water Research2008，42，20： | 1 |
| 16 | Hypertriglyceridemia and risk of coronary heart disease显示文摘 | Hokanson JE | 2002 | Lipid Abnormalities2002，4，6： | 1 |
| 17 | A comparison of selfesteem lability and low trait self-esteem as vulnerability factors for depression显示文摘 | Butler AC Hokanson JE Flynn HA | | 0，，： | 1 |
| 18 | Dyslipidemia ofcentral obesity and insulin Resistance显示文摘 | BRUNZELL J D HOKANSON J E | 1999 | DiabetesCare1999，223，4： | 1 |
| 19 | Microsatellite (SSR) variation in collection of Malus(apple) species and hybrids显示文摘 | HOKANSON S C LAMBOY W F SZEWC-MCFADDEN A K MCFERSON J R | 2001 | Euphytica2001，118，： | 1 |
| 20 | Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality显示文摘 | ARCAROLI JJ HOKANSON JE ABRAHAM EG | 2009 | Am J Resp& Crit Care Med2009，179，2： | 1 |
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