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| 1 | High-density lipoproteins:an emerging target in the prevention of cardiovascular disease显示文摘高密度的脂蛋白(HDL ) 很好被建立了免于动脉粥样硬化患者的发展心血管的疾病。除了反向的胆固醇运输的提升, HDL 拥有可以在动脉的墙上贡献他们的有益的影响的很多个另外的功能的性质,变得明显。很多令人激动的治疗学的策略被开发了免于动脉粥样硬化患者的发展的那目标 HDL 和它的能力匾。这篇论文将考察 HDL 的功能的性质的提升怎么与确定的疾病在病人禁止动脉粥样硬化患者匾和 stabilises 损害的形成。 | Belinda A Cutri Neil J Hime Stephen J Nicholls | 2006 | Cell Research2006，16，10： | 6 |
| 2 | RNA binding proteins in spermatogenesis: an in depth focus on the Musashi family显示文摘控制基因规定为维持繁殖潜力在配偶子开发期间是重要的。在哺乳动物的精子发生的复杂过程期间,尽管有重翻译要求,男细菌房间为继续的生长和区别经历不活跃的抄写的扩大时期。因此,精子发生高度依赖基因表示的 posttranscriptional 规定的机制,由 RNA 有约束力的蛋白质(RBP ) 便于,它仍然保持富有地在整个这进程表示了。一如此的组蛋白质是 Musashi 家庭,以前在果蝇识别了睾丸细菌房间开发和成熟分裂的同样批评的管理者,并且也出现对在老鼠的精子开发和繁殖潜力重要。这评论在男细菌房间开发的范围以内描述 RBP 的角色和函数,集中于我们在精子发生的 Musashi 蛋白质的最近的知识。RBP 在房间以内利用的功能的机制在与模式的关系深入地亚 cellular 本地化和阶段特定的表示的,和意义被构画出, posttranscriptional 规定的影响也被加亮。当原来在果蝇和 Xenopus 描绘了,我们在干细胞功能和房间命运决心强调 RBP 的 Musashi 家庭的历史的角色,并且与我们微分角色的当前的理解和哺乳动物的 Musashi 蛋白质, Musashi-1 和 Musashi-2 的功能得出结论,与我们在精子发生的调查结果的一个主要焦点。这评论两个都作为男配偶子开发的主人管理者加亮 RBP 的必要贡献到 posttranscriptional 规定和 Musashi 家庭的重要性。 | Jessie M Sutherland Nicole A Siddall Gary R Hime Eileen A McLaughlin | 2015 | Asian Journal of Andrology2015，17，4： | 4 |
| 3 | Central line-associated bloodstream infection among children with biliary atresia listed for liver transplantation显示文摘BACKGROUND Pre-transplant nutrition is a key driver of outcomes following liver transplantation in children.Patients with biliary atresia(BA) may have difficulty achieving satisfactory weight gain with enteral nutrition alone,and parenteral nutrition(PN) may be indicated.While PN has been shown to improve anthropometric parameters of children with BA listed for liver transplantation,less is known about the risks,particularly infectious,associated with this therapy among this specific group of patients.AIM To describe the incidence,microbiology,and risk factors of central line-associated bloodstream infection(CLABSI) among children with BA listed for liver transplantation.METHODS Retrospective review of children aged ≤ 2-years of age with BA who were listed for primary liver transplantation at Texas Children's Hospital from 2008 through2015(n = 96).Patients with a central line for administration of PN(n = 63) were identified and details of each CLABSI event were abstracted.We compared the group of patients who experienced CLABSI to the group who did not,to determine whether demographic,clinical,or laboratory factors correlated with development of CLABSI.RESULTS Nineteen of 63 patients(30%,95%CI:19,43) experienced 29 episodes of CLABSI during 4800 line days(6.04 CLABSI per 1000 line days).CLABSI was predominantly associated with Gram-negative organisms(14/29 episodes,48%)including Klebsiella spp.,Enterobacter spp.,and Escherichia coli.The sole polymicrobial infection grew Enterobacter cloacae and Klebsiella pneumoniae.Grampositive organisms(all Staphylococcus spp.) and fungus(all Candida spp.)comprised 9/29(31%) and 6/29(21%) episodes,respectively.No demographic,clinical,or laboratory factors were significantly associated with an increased risk for the first CLABSI event in Cox proportional hazards regression analysis CONCLUSION There is substantial risk for CLABSI among children with BA listed for liver transplantation.No clinical,demographic,or laboratory factor we tested emerged as an independent predictor of CLABSI.While our data did not show an impact of CLABSI on the short-term clinical outcome,it would seem prudent to implement CLABSI reduction strategies in this population to the extent that each CLABSI event represents potentially preventable hospitalization,unnecessary healthcare dollar expenditures,and may exact an opportunity cost,in terms of missed allograft offers. | Nicole D Triggs Stacey Beer Sonam Mokha Kat Hosek Danielle Guffey Charles G Minard Flor M Munoz Ryan W Himes | 2019 | World Journal of Hepatology2019，11，2： | 2 |
| 4 | Regulation of cell adhesion in the testis: a new role for p73显示文摘在成年睾丸的男细菌房间在他们从 spermatogonial 干细胞转移到直的基因表示侧面和形态学经历的戏剧的变化成熟精子依赖于他们有 Sertoli 房间的协会。Sertoli 房间为男细菌房间的幸存和成熟是关键的。二份最近的报纸, Holembowski et al.1 和 Inoue et al.2 为 p53 家庭成员,描述了一个令人吃惊的角色 p73,在细菌 cell-Sertoli 的规定房间粘附。 | Helen E Abud Gary R Hime | 2014 | Asian Journal of Andrology2014，16，6： | 2 |
| 5 | Diagnostic and therapeutic role of endoscopic retrograde cholangiopancreatography in biliary rhabdomyosarcoma显示文摘Biliary rhabdomyosarcoma (BRMS) is an uncommon childhood malignancy which has been managed surgically. We present a case of a 3-year-old boy with BRMS, in whom endoscopic retrograde cholangiopancreatography (ERCP) was successfully used both diagnostically and therapeutically, thus obviating the need for surgery and its attendant risks of morbidity and mortality. We conclude that ERCP is an effective alternative to surgery for BRMS in some patients. | Ryan W Himes Isaac Raijman Milton J Finegold Heidi V Russell Douglas S Fishman | 2008 | World Journal of Gastroenterology2008，14，30： | 2 |
| 6 | Sciatic nerve transaction produce death of dorsal root ganglion cell and reversible loss of substance P in the spinal cord显示文摘 | Tessler A Himes BT Krieger NR | 1985 | Brain Res1985，332，： | 1 |
| 7 | Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis显示文摘 | Gumey M E Fleck T J Himes C S | 1998 | Neurology1998，50，： | 1 |
| 8 | sciatic nerve transaction Produce death of dorsal root ganglion cell and reversible loss of substance P in the spinal cord显示文摘 | Tessler A Himes BT Krieger NR | 1985 | brain Res1985，332，： | 1 |
| 9 | Neurotrophin- 3 prevents death of axotomized Clarke's nucleus neurons in adult rat 显示文摘 | SHBAYAMA M HATTORI S HIMES B T | 1998 | J Comp Neurol1998，390，： | 1 |
| 10 | An early handwrist atlas and its implications for secular change in bone age显示文摘 | Himes J H | 1984 | Ann Hum Biol1984，11，1： | 1 |
| 11 | Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovims显示文摘 | Liu Y Himes BT Solowska J | 1999 | Exp Neurol1999，158，1： | 1 |
| 12 | Immunodiagnosis of human Sparganosis mansoni by micro-chemiluminescence enzyme-linked immunosorbent assay显示文摘 | Nishiyama T Ide T Himes SR Jr | 1994 | Trans R Soc Trop Med Hyg1994，88，6： | 1 |
| 13 | Posted speed limit: To includ~~ or not to include in operating speed models 显示文摘 | Himes S C Donnel| E T Porter R J | 2013 | Transportation Researeh Part A2013，52，： | 1 |
| 14 | Thl7 cells in cancer: the ultimate identity crisis 显示文摘 | Bailey SR Nelson MH Himes RA | 2014 | Front Immunol2014，175，： | 1 |
| 15 | Time from cervical conization to pregnancy and preterm birth显示文摘 | Himes KP Simhan HN | 2007 | Obstet Gynecol2007，109，： | 1 |
| 16 | Axon growth and recovery of function supported by human bone marrow stromal cells in the injured spinal cord exhibit donor variations显示文摘 | Neuhuber B Himes BT Shumsky JS | | 0，，01： | 1 |
| 17 | The Musashi fam-ily of RNA binding proteins:master regulators of multiple stem cellpopulations显示文摘 | Sutherland JM McLaughlin EA Hime GR | | 0，，： | 1 |
| 18 | Prenatal tobacco exposure,biomarkers for tobacco in meconium,and neonatal growth outcomes显示文摘 | Himes SK Stroud LR Scheidweiler KB | 2012 | J Pediatr2012，1，12： | 1 |
| 19 | Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus显示文摘 | Liu Y Himes BT Solowska J | 1999 | Exp Neurol1999，158，1： | 1 |
| 20 | Frequency domain FIR filter design using fuzzy adaptive simulated annealing显示文摘 | HIME A O ANTONIO P MAR1ANE R P | 2009 | Circuits Systems and Signal Processing2009，28，6： | 1 |
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