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| 1 | Quality of life, physical performance and nutritional status in older patients hospitalized in a cardiology department显示文摘Objectives Quality of life(QoL) is a priority outcome in older adults suffering from cardiovascular diseases. Frailty and poor nutritional status may affect the QoL through mobility disorders and exhaustion. The objective of this study was to determine if physical frailty and nutritional status were associated with QoL, in older cardiology patients. Methods Cross sectional, observational study conducted in a cardiology department from a university hospital. Participants(n = 100) were aged 70 and older. Collected data included age, sex, cardiac diseases, New York Heart Association(NYHA) classification, comorbidities(Charlson Index) and disability. A Short Physical Performance Battery(SPPB), including walking speed assessment was performed;handgrip strength were measured as well as Fried’s frailty phenotype. Nutritional status was assessed using the Mini Nutritional Assessment(MNA) and Body Mass Index(BMI), inflammation by C-reactive protein(CRP). QoL was assessed using the EORTC–QLQ questionnaire. Univariate and multivariate analyses were performed to study the associations between all recorded parameters and QoL. Results In participants(mean age: 79.3 ± 6.7 years;male: 59%), Charlson index, arrhythmia, heart failure, NYHA class III-IV, MNA, disability, walking speed, SPPB score, frailty and CRP were significantly associated with QoL in univariate analysis. Multivariate analysis showed that NYHA class III-IV(P < 0.001), lower MNA score(P = 0.03), frailty(P < 0.0001), and higher CRP(P < 0.001) were independently associated with decreased QoL. Conclusions Frailty, nutritional status and inflammation were independently associated with poor QoL. Further studies are needed to assess the efficacy of nutritional and physical interventions on QoL in this population. | Matthieu Lilamand Mariannick Saintout Marie Vigan Astrid Bichon Laure Tourame Aurélie Brembilla Diet Bernard Iung Dominique Himbert Cédric Laouenan Agathe Raynaud-Simon | 2020 | Journal of Geriatric Cardiology2020，17，7： | 3 |
| 2 | Enalapril improves arterial elastic properties in rats with myocardial infarction显示文摘 | Driss AB Himbert C Poitevin P | 1999 | J Cardiovasc Pharmacol1999，34，1： | 2 |
| 3 | Unexpected complications of transapical aortic valve implantation显示文摘 | Al-Attar N Ghodbane W Himbert D | | 0，，01： | 1 |
| 4 | Conservative management of patients with acute myocardial infarction and spontaneous acute patency of the infarct- related artery显示文摘 | Steg PC Himbert D Benamer H | 1997 | Am Heart J1997，134，： | 1 |
| 5 | Can we provide reperfusion therapy to all unselected patients admired with acute myocardial infarction显示文摘 | Juliard JM Himbert D Golmard JL | 1997 | J Am Coll Cardiol1997，30，： | 1 |
| 6 | Reappraisal of percutaneous aortic balloon valvuloplasty as a preliminary treatment strategy in the transcatheter aortic valve implantation era 显示文摘 | Tissot CM Attias D Himbert D | 2011 | Eurolntetwention2011，7，1： | 1 |
| 7 | Reinterventions after percutaneous mitral commissurotomy during long - term follow - up, up to 20 years : the role of repeat percutaneous mitral commissurotomy 显示文摘 | BOULET1 C IUNG B HIMBERT D | 2013 | EurHeart J2013，34，25： | 1 |
| 8 | Molar mass of dry air in mass metrology显示文摘 | Khelifa N Lecollinet M Himbert M | 2007 | Measurement2007，40，78： | 1 |
| 9 | Unstable angina in the elderly 显示文摘 | Himbert D | 2001 | Am Cardiol Angeiol (Paris)2001，50，78： | 1 |
| 10 | Results of transfemoral or transapical aortic valve implantation following a uniform assessment in high-risk patients with aortic stenosis 显示文摘 | Himbert D Descoutures F A1-Attar N | 2009 | J Am Coil Cardiol2009，54，4： | 1 |
| 11 | Transcathetervalve-in-ring implantation after failure of surgical mitralrepair 显示文摘 | Descoutures F Himbert D Maisano F | 2013 | Eur J Cardiothorac Surg2013，44，1： | 1 |
| 12 | Wear mechanisms of new tool materials for Ti6AI4V high performance machining 显示文摘 | Corduan N Himbert T Poulachon G | 2003 | CIRP Annals-Manufacturing Technology2003，52，1： | 1 |
| 13 | Determinants of significant paravalvular regurgitation after transcatheter aortic valve:implantation impact of device and annulus discongruence显示文摘 | Détaint D Lepage L Himbert D | 2009 | JACC Cardiovasc Interv2009，2，9： | 1 |
| 14 | Reinterventions after percutaneous mitral commissurotomy during long-term follow-up,up to20 years:the role of repeat percutaneous mitral commissurotomy显示文摘 | Bouleti C Iung B Himbert D | 2013 | Eur Heart J2013，34，5： | 1 |
| 15 | Contemporary surgical or percutaneous management of severe aortic stenosis in the elderly显示文摘 | Himbert D Lepage L | 2008 | Eur Heart J2008，29，11： | 1 |
| 16 | Foreword: Progress in the experimental determination of Boltzmann' s constant 显示文摘 | Borde C J Himbert M E | 2009 | C R Physique2009，10，9： | 1 |
| 17 | Enhanced Shear-Induced Platelet Aggregation in Patients Who Experience Subacute Stent Thrombosis显示文摘 | Nadine Ajzenberg Pierre Aubry Marie-Genevieve Huisse Agnés Cachier Walid El Amara Laurent J. Feldman Dominique Himbert Dominique Baruch Marie-Claude Guillin Ph. Gabriel Steg | 2005 | Journal of the American College of Cardiology2005，，： | 1 |
| 18 | A matched comparison of the combinaton of prehospital thrombolysis and standby rescue angioplasty with primary angioplasty显示文摘 | Himbert D Cristofini P | 1999 | Am J Cardiol1999，83，3： | 1 |
| 19 | Reinterventions afterpercutaneous mitral commissurotomy during long-term follow-up, upto 20 years: the role of repeat percutaneous mitral commissurotomy显示文摘 | Bouleti C Iung B Himbert D | 2013 | Eur Heart J2013，34，25： | 1 |
| 20 | Results of transfemoral or transapical aortic valve implantation following a uniform assessment in high-risk patients with aortic stenosis显示文摘 | Himbert D Descoutures F Al-Attar N | 2009 | J Am Coll Cardiol2009，54，4： | 1 |
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