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| 1 | 1700 nm optical coherence microscopy enables minimally invasive,label-free,in vivo optical biopsy deep in the mouse brain显示文摘In vivo,minimally invasive microscopy in deep cortical and sub-cortical regions of the mouse brain has been challenging.To address this challenge,we present an in vivo high numerical aperture optical coherence microscopy(OCM)approach that fully utilizes the water absorption window around 1700nm;where ballistic attenuation in the brain is minimized.Key issues,including detector noise,excess light source noise,chromatic dispersion,and the resolution-speckle tradeoff,are analyzed and optimized.Imaging through a thinned-skull preparation that preserves intracranial space,we present volumetric imaging of cytoarchitecture and myeloarchitecture across the entire depth of the mouse neocortex,and some sub-cortical regions.In an Alzheimer's disease model,we report that findings in superficial and deep cortical layers diverge,highlighting the importance of deep optical biopsy.Compared to other microscopic techniques,our 1700nm OCM approach achieves a unique combination of intrinsic contrast,minimal invasiveness,and high resolution for deep brain imaging. | Jun Zhu Hercules Rezende Freitas Izumi Maezawa Lee-way Jin Vivek J.Srinivasan | 2021 | Light(Science & Applications)2021，10，8： | 3 |
| 2 | LC-MS/MS signal suppression effects in the anaysis of pesticides in complex environmental matrices显示文摘 | Choi B K Hercules D M Gusev A I | 2001 | Fresenius'' Journal of Analytical Chemistry2001，369，34： | 1 |
| 3 | Studies of nickel-tungsten alumina catalysts by X-ray photoelectron spectroscopy 显示文摘 | NG K T HERCULES D M | 1976 | J Phys Chem1976，80，19： | 1 |
| 4 | Current Practices in Sedation and Analgesia for Mechanically Ventilated Critically Ill Patients: A Prospective Multicenter Patient-based Study显示文摘 | Jean-Francois Payen Gérald Chanques Jean Mantz Christiane Hercule Igor Auriant Jean-Luc Leguillou Michèle Binhas Céline Genty Carole Rolland Jean-Luc Bosson | 2007 | Anesthesiology2007，，4： | 1 |
| 5 | Surface spectroscopic characterization of cobalt-molybdenum-alumina catalysts 显示文摘 | Roland L Chin David M Hercules | 1982 | Phys Chem1982，86，： | 1 |
| 6 | Studies of Supported Nickel Cata- lysts by X-Ray Photoelectron and Ion Scattering Spectroscopies 显示文摘 | Milton Wu David M Hercules | 1979 | J Phy Chem1979，83，15： | 1 |
| 7 | An X- ray photoelectron (ESCA) and laser raman spectroscopic investigation of aluminum perrhenate显示文摘 | SALVATI L JONENS G L HERCULES D M | 1980 | App Spectros1980，34，： | 1 |
| 8 | MALDI-TOF MS study of aromatic polybenzoxazole fibers 显示文摘 | GIES A P HERCULES D M | 2006 | Macromolecules2006，39，7： | 1 |
| 9 | Surface spectroscopic characterization of Mn/AI2 03 catalysts显示文摘 | Strohmeier B R Hercules D M | 1984 | J Phys Chem-Us1984，88，： | 1 |
| 10 | 显示文摘 | Zhuang H Gardella Jr J A Hercule D M | 1997 | Macromolecules1997，30，4： | 1 |
| 11 | Studies of nickel-tungsten-alumina catalysts by X-ray photoelectron spectroscopy显示文摘 | Ng K T Hercules D M | 1976 | J Phys Chem1976，80，26： | 1 |
| 12 | A Dynamic Stochastic Programming Model for International Portfolio Management显示文摘 | NIKOLAS T HERCULES V STAVROS A Z | 2006 | European Journal of Operational Research2006，1，6： | 1 |
| 13 | Apparent resistivity and spectral induced polarization in the submarine environment 显示文摘 | Hercules D S Edson E S | 2001 | Anais da academia brasileira de ciencias2001，73，3： | 1 |
| 14 | Angiotensin II Type 1 Receptor Inhibition is Associated with Reduced Tachyarrhythmia-Induced Ventricular Interstitial Fibrosis in a Goat Atrial Fibrillation Model显示文摘 | Stavros I. Chrysostomakis Ioannis K. Karalis Emmanuel N. Simantirakis Anastasios V. Koutsopoulos Hercules E. Mavrakis Gregory I. Chlouverakis Panos E. Vardas | 2007 | Cardiovascular Drugs and Therapy2007，，5： | 1 |
| 15 | Surface functionalization and characterization of graphitic carbon nanofibers (GCNFs)显示文摘 | Jiang Li Matthew J. Vergne Eric D. Mowles Wei-Hong Zhong David M. Hercules Charles M. Lukehart | 2005 | Carbon2005，，14： | 1 |
| 16 | Studies of nickel-tungstenalumina catalysts by X-ray photoelectron spectroscopy 显示文摘 | Kung T Ng David M Hercules | 1976 | The Journal of Physical Chemistry A1976，80，19： | 1 |
| 17 | Fluorometric determination of 1-and 2- naphthol in mixtures显示文摘 | Hercules D M Rogers L | 1958 | Anal Chem1958，30，1： | 1 |
| 18 | A Dynamic Stochastic Programming Model for International Portfolio Management显示文摘 | Nikolas Topaloglou Hercules Vladimirou Stavros A Zenios | 2006 | European Journal of Operational Research2006，1，6： | 1 |
| 19 | CVaR Models with selective hedging international assets allocation 显示文摘 | Nikolas T Hercules V Stavros A | 2003 | Journal of Banking & Finance2003，26，： | 1 |
| 20 | Modelling of Water Pollution in the Thermaios Gulf with Fuzzy Parameters显示文摘 | Hercules M Petro A Jacques G | 2001 | Ecological Modelling2001，142，12： | 1 |
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