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| 1 | 天然地震接收函数揭示的青藏高原东部地壳结构显示文摘 | 钱辉 姜枚 薛光琦 宿和平 Gerard Wittlinger Jerome Vergne | 2001 | 地震学报2001，23，1： | 20 |
| 2 | 青藏高原东北部天然地震探测与岩石圈深部特征显示文摘为了研究青藏高原东北部块体构造变形的深部驱动机制 ,笔者对青藏高原东北部的天然地震观测数据进行地震层析反演 ,并结合同一剖面的接收函数及各向异性结果进行讨论。介绍了ACH方法的基本原理 ,论述了由于印度板块向北俯冲的强大的持续作用力 ,造就了NE向俯冲到柴达木盆地之下的昆仑造山带 ,并发现在巴颜喀拉地体下方壳幔内的仰冲活动。壳幔内的低速体十分显著地出现在阿尼玛卿缝合线以北 ,深度可达 30 0km。推断该低速体可能与昆仑断裂在深层的剪切作用有关。深部资料显示该区莫霍界面由北向南逐渐加深 ,这与青藏高原东北部的岩石圈减薄现象一致 ,而且与印度板块向北运动的远程效应有关。另外 ,地震层析结果及各向异性分析也支持青藏高原东北部主应力方向转为NE向的观点。 | 薛光琦 钱辉 姜枚 宿和平 董英君 Gerard Wittlinger Jerome Vergne Georges Poupinet | 2003 | 地球学报2003，24，1： | 17 |
| 3 | Trophic factors are essential for the survival of grafted oligodendrocyte progenitors and for neuroprotection after perinatal excitotoxicity显示文摘The consequences of neonatal white matter injury are devastating and represent a major societal problem as currently there is no cure.Prematurity,low weight birth and maternal pre-natal infection are the most frequent causes of acquired myelin deficiency in the human neonate leading to cerebral palsy and cognitive impairment.In the developing brain,oligodendrocyte(OL)maturation occurs perinatally,and immature OLs are particularly vulnerable.Cell replacement therapy is often considered a viable option to replace progenitors that die due to glutamate excitotoxicity.We previously reported directed specification and mobilization of endogenous committed and uncommitted neural progenitors by the combination of transferrin and insulin growth factor 1(TSC1).Here,considering cell replacement and integration as therapeutic goals,we examined if OL progenitors(OLPs)grafted into the brain parenchyma of mice that were subjected to an excitotoxic insult could rescue white matter injury.For that purpose,we used a well-established model of glutamate excitotoxic injury.Four-day-old mice received a single intraparenchymal injection of the glutamate receptor agonist N-methyl-D-aspartate alone or in conjunction with TSC1 in the presence or absence of OLPs grafted into the brain parenchyma.Energetics and expression of stress proteins and OL developmental specific markers were examined.A comparison of the proteomic profile per treatment was also ascertained.We found that OLPs did not survive in the excitotoxic environment when grafted alone.In contrast,when combined with TSC1,survival and integration of grafted OLPs was observed.Further,energy metabolism in OLPs was significantly increased by N-methyl-D-aspartate and modulated by TSC1.The proteomic profile after the various treatments showed elevated ubiquitination and stress/heat shock protein 90 in response to N-methyl-D-aspartate.These changes were reversed in the presence of TSC1 and ubiquitination was decreased.The results obtained in this pre-clinical study indicate that the use of a combinatorial intervention including both trophic support and healthy OLPs constitutes a promising approach for long-term survival and successful graft integration.We established optimal conditioning of the host brain environment to promote long-term survival and integration of grafted OLPs into an inflamed neonate host brain.Experimental procedures were performed under the United States Public Health Service Guide for the Care and Use of Laboratory Animals and were approved by the Institutional Animal Care Committee at(UCLA)(ARC#1992-034-61)on July 1,2010. | Megumi Hirose-Ikeda Brian Chu Paul Zhao Omar Akil Elida Escalante Laurent Vergnes Carlos Cepeda Araceli Espinosa-Jeffrey | 2020 | Neural Regeneration Research2020，15，3： | 4 |
| 4 | Microfluidic actuators based on temperature-responsive hydrogels显示文摘The concept of using stimuli-responsive hydrogels to actuate fluids in microfluidic devices is particularly attractive,but limitations,in terms of spatial resolution,speed,reliability and integration,have hindered its development during the past two decades.By patterning and grafting poly(N-isopropylacrylamide)PNIPAM hydrogel films on plane substrates with a 2μm horizontal resolution and closing the system afterward,we have succeeded in unblocking bottlenecks that thermo-sensitive hydrogel technology has been challenged with until now.In this paper,we demonstrate,for the first time with this technology,devices with up to 7800 actuated micro-cages that sequester and release solutes,along with valves actuated individually with closing and opening switching times of 0.6±0.1 and 0.25±0.15 s,respectively.Two applications of this technology are illustrated in the domain of single cell handling and the nuclear acid amplification test(NAAT)for the Human Synaptojanin 1 gene,which is suspected to be involved in several neurodegenerative diseases such as Parkinson’s disease.The performance of the temperature-responsive hydrogels we demonstrate here suggests that in association with their moderate costs,hydrogels may represent an alternative to the actuation or handling techniques currently used in microfluidics,that are,pressure actuated polydimethylsiloxane(PDMS)valves and droplets. | Loïc D'Eramo Benjamin Chollet Marie Leman Ekkachai Martwong Mengxing Li Hubert Geisler Jules Dupire Margaux Kerdraon Clémence Vergne Fabrice Monti Yvette Tran Patrick Tabeling | 2018 | Microsystems & Nanoengineering2018，4，1： | 3 |
| 5 | Optimization of maize microspore isolation and culture conditions for reliable plant regeneration显示文摘 | Antoine Gaillard Philippe Vergne Michel Beckert | 1991 | Plant Cell Reports1991，，2： | 2 |
| 6 | Genetic toxicology studies with glutaraldehyde显示文摘 | Vergnes JS Ballantyne B | 2002 | J Appl Toxicol2002，22，1： | 1 |
| 7 | High-fat diet induces periodontitis in mice through lipopolysaccharides(LPS)receptor signaling:protective action of estrogens显示文摘 | BLASCO-BAQUE V SERINO M VERGNES J N | 2012 | PLoS One2012，7，48： | 1 |
| 8 | Relationships between mastication conditions and rheological behavior of a natural rubber 显示文摘 | Dimier F Vergnes B Vincent M | 2004 | Rheol Acta2004，43，2： | 1 |
| 9 | Breast cancer and DNA repair capacity: association with use of nmhivitamin and calcium supplements 显示文摘 | Vergne Y Matta J Morales L | 2013 | Integr Med (Encinitas)2013，12，3： | 1 |
| 10 | Auto-organisation in silica-based organicinorganic gels obtained by sol gel process 显示文摘 | Vergnes A | 2003 | J Sol-Gel Sci Teehn2003，26，： | 1 |
| 11 | Efficacy of periodontal treatment on glycaemic control in diabetic patients: A meta-analysis of interventional studies显示文摘 | Darre L Vergnes IN Gourdy P | 2008 | Diabetes Metab2008，34，5： | 1 |
| 12 | Cohomologie des algebres de Lie nilpotentes,Application a l'etude de la varete des algebres de Lie nilpotentes显示文摘 | Vergne M | 1970 | Bull Soc Math France1970，98，： | 1 |
| 13 | Evolution of the Peroxide-induced Degradation of Polypropylene along a Twinscrew Extruder: Experimental Data and Theoretical Predictions 显示文摘 | F Berzin B Vergnes S V Canevarolo | 2006 | J Appl Polym Sci2006，99，5： | 1 |
| 14 | Concomitant ankylosing spondylitis and S]ogren 's syndrome 显示文摘 | Treves R Vergne P Bonnet C | 1998 | Rev RheumEngEd1998，65，12： | 1 |
| 15 | The role of PI3P phosphatases in the regulation of autophagy显示文摘 | Vergne I Deretic V | | 0，，7： | 1 |
| 16 | Modeling of peroxide initiated controlled degradation of polypropylene in a twin screw extruder 显示文摘 | BERZIN F VERGNES B DUFOSSE P | 2000 | Polym Eng Sci2000，40，2： | 1 |
| 17 | Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and autophagy as a host defence mechanism显示文摘 | Deretic V Singh S Master S Harris J Roberts E Kyei G Davis A Haro S Naylor J Lee HH Vergne I | | Cell Microbiol0，8，5： | 1 |
| 18 | Modeling of reactive system in twin-screw extrusion: challenges and applications显示文摘 | Vergnes B Berzin F | 2006 | Comptes Rendus Chimie2006，9，11： | 1 |
| 19 | Heart-type fatty acid-bindingprotein is essential for efficient brown adipose tissue fatty acidoxidation and cold tolerance显示文摘 | Vergnes L Chin R Young SG | 2011 | J Biol Chem2011，286，1： | 1 |
| 20 | Green corridors in urban landscapes affect the arthropod communities of domestic gardens显示文摘 | Vergnes A Viol I L Clergeau P | 2012 | Biological Conservation2012，145，1： | 1 |
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