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| 1 | Comparison of tumor response following conventional versus drug-eluting bead transarterial chemoembolization in early-and very early-stage hepatocellular carcinoma显示文摘Objective:To compare the safety of conventional transarterial chemoembolization(cTACE)vs drug-eluting bead TACE(DEB-TACE)in very early-and early-stage hepatocellular carcinoma(HCC).Methods:Data of patients with early-and very early-stage HCC treated with cTACE or DEB-TACE were evaluated retrospectively in this study.A total of 40 patients were included,20 treated with cTACE and 20 with DEB-TACE.The cTACE and DEB-TACE groups were comprised of 80%and 75%males,while there were 20%females in cTACE group and 25%in Deb-TACE group respectively.The mean age of patients in cTACE group was 57.43+5.6 years,while it was 56.4+5.5 years in DEB-TACE group.All patients had liver status of Child–Pugh Class A and a score≤7 in Child-Pugh class type B in very early-(stage 0)or early-phase(stage A)stages according to the Barcelona Clinic Liver Cancer(BCLC)system.Results:The Child-Pugh class degradation in the cTACE group was slightly higher than that in the DEB-TACE group.Serious complications like peritumoral parenchymal ischemia were observed in 4 patients in the cTACE group and 5 in the DEB-TACE group.Localized bile duct dilation was seen in 2 patients in the cTACE group and 6 in the DEB-TACE group.No significant variation in serious complications between the two groups was established in localized bile duct dilatation.Other minor complications noted were liver failure,liver abscess,liver infarction,acute cholecystitis,biliary tree necrosis,and mortality.Further,no substantial variation in tumor response between the groups was reported immediately and 1-year post-procedural assessment.Conversion rate to other treatment modalities such as surgical resection,radiofrequency ablation(RFA),or swap between cTACE and DEB-TACE was substantially higher in the DEB-TACE group(40%)than in the cTACE group(10%)at the 1-year completion period of the study.Conclusion:In terms of tumor response,the DEB-TACE group showed a better response,to some extent,as an initial therapy for HCC in the early stages as compared to the cTACE group,and DEB-TACE also exhibited better clinical efficacy in patients with HCC. | Murtuza Razi Syed Safiullah Jianping Gu Xu He Mustafa Razi Jie Kong | 2022 | Journal of Interventional Medicine2022，5，1： | 3 |
| 2 | Diapir structure and its constraint on gas hydrate accumulation in the Makran accretionary prism, offshore Pakistan显示文摘The Makran accretionary prism is located at the junction of the Eurasian Plate,Arabian Plate and Indian Plate and is rich in natural gas hydrate(NGH)resources.It consists of a narrow continental shelf,a broad continental slope,and a deformation front.The continental slope can be further divided into the upper slope,middle slope,and lower slope.There are three types of diapir structure in the accretionary prism,namely mud diapir,mud volcano,and gas chimney.(1)The mud diapirs can be grouped into two types,namely the ones with low arching amplitude and weak-medium activity energy and the ones with high arching amplitude and medium-strong activity energy.The mud diapirs increase from offshore areas towards onshore areas in general,while the ones favorable for the formation of NGH are mainly distributed on the middle slope in the central and western parts of the accretionary prism.(2)The mud volcanoes are mainly concentrated along the anticline ridges in the southern part of the lower slope and the deformation front.(3)The gas chimneys can be grouped into three types,which are located in piggyback basins,active anticline ridges,and inactive anticline ridges,respectively.They are mainly distributed on the middle slope in the central and western parts of the accretionary prism and most of them are accompanied with thrust faults.The gas chimneys located at different tectonic locations started to be active at different time and pierced different horizons.The mud diapirs,mud volcanoes,and gas chimneys and thrust faults serve as the main pathways of gas migration,and thus are the important factors that control the formation,accumulation,and distribution of NGH in the Makran accretionary prism.Mud diapir/gas chimney type hydrate develop in the middle slope,mud volcano type hydrate develop in the southern lower slope and the deformation front,and stepped accretionary prism type hydrate develop on the central and northern lower slope.The middle slope,lower slope and deformation front in the central and western parts of the Makran accretionary prism jointly constitute the NGH prospect area. | Zhen Zhang Gao-wen He Hui-qiang Yao Xi-guang Deng Miao Yu Wei Huang Wei Deng Syed Waseem Haider Naimatullah Sohoo Noor Ahmed Kalhoro | 2020 | China Geology2020，3，4： | 2 |
| 3 | Histamine excites neurons of the inferior vestibular nucleus in rats by activation of Hl and H2 receptors显示文摘 | Peng SY Zhuang QX He YC | 2013 | Neurosci Lett2013，541，： | 1 |
| 4 | Heterogeneity for stern cell- related markers according to tumor subtype and histologic stage in breast cancer显示文摘 | Park SY Lee HE Li H | 2010 | Clin Cancer Res2010，16，3： | 1 |
| 5 | Smoking and depressive symp- toms in Chinese elderly in Hong Kong 显示文摘 | Lam TH Li ZB He SY | 2004 | Acta Psychiatr Scartd2004，110，3： | 1 |
| 6 | Advanced gastric cancer in jordan from 2004 to 2008 : a study of epidemiol- ogy and outcomes 显示文摘 | Abbasi SY Taani HE Saad A | 2011 | Gastrointest Cancer Res2011，4，4： | 1 |
| 7 | A homogenous nature of n- ative Chinese duck matrilineal pool 显示文摘 | He DQ Zhu Q Chen SY | 2008 | BMC Evolutionary Biology2008，8，1： | 1 |
| 8 | Promoter CpG island hypermethylation during breast cancer progression显示文摘 | PARK SY KWON HJ LEE HE | | 0，，01： | 1 |
| 9 | Relativity of hippocampal-HPA- PTSD显示文摘 | Chen SY He W Shi YX | 2010 | Chin Foreign Med Treat2010，25，： | 1 |
| 10 | Evaluation of 18F-labeled targeted perfluorocarbon-filled albumin mierobubbles a probe for miemUS and microPET in tumor-bearing mince 显示文摘 | Liao AH Wu SY Wang HE | 2012 | Ultrasonics2012，53，2： | 1 |
| 11 | Degradation of residual lignin in kraft pulp by laccase and mediator system显示文摘 | Fu SY Zhan HY He W | 2002 | Journal of South China University Of Teehnology(Natural Science E- dition)2002，12，30： | 1 |
| 12 | Degradation of residual lignin in Kraft Pulp by laccase and mediator system显示文摘 | Fu SY Zhan HY He W | 2002 | Journal of south china university of technology2002，30，12： | 1 |
| 13 | Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer显示文摘 | Park SY Lee HE Li H | 2010 | Clin Cancer Res2010，16，3： | 1 |
| 14 | Epilepsy surgery in pediatric intractable epilepsy with destructive encephalopathy显示文摘 | Park SY Kwon HE Kang HC | 2013 | J Epilepsy Res2013，3，2： | 1 |
| 15 | The genetic drift of human pa- pillomavirus type 16 is a means of reconstructing prehistoric viral spread and movement of ancient populations 显示文摘 | He I Chan SY Burk RD | 1993 | J Virol1993，67，11： | 1 |
| 16 | OPG inhibits gene expression of RANK and CAII in mouse osteoclast-like cell显示文摘 | Chen J He JQ Zhen SY | | 0，，： | 1 |
| 17 | Bone formation on the apa- tite-coated zirconia porous scaffolds within a rabbit calvarial de-feet显示文摘 | Kim HW Shin SY Kim HE | 2008 | J Biomater Appl2008，22，6： | 1 |
| 18 | Epilepsy surgery in podi-atric intractable epilepsy with destructive encephalopathy 显示文摘 | Park SY Kwon HE Kang HC | 2013 | J Epilepsy Res2013，3，2： | 1 |
| 19 | Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer显示文摘 | Park SY Lee HE Li H | 2010 | Cancer Res2010，16，3： | 1 |
| 20 | A zebrafish phenotypic assay for assessing drug - induced hepatotoxicity 显示文摘 | He JH Guo SY Zhu F | 2013 | Pharmacol Toxico! Meth2013，67，1： | 1 |
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