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| 1 | Optimal central venous pressure during partial hepatectomy for hepatocellular carcinoma显示文摘BACKGROUND:Low central venous pressure(CVP) affects hemodynamic stability and tissue perfusion.This prospective study aimed to evaluate the optimal CVP during partial hepatectomy for hepatocellular carcinoma(HCC).METHODS:Ninety-seven patients who underwent partial hepatectomy for HCC had their CVP controlled at a level of 0 to 5 mmHg during hepatic parenchymal transection.The systolic blood pressure(SBP) was maintained,if possible,at 90 mmHg or higher.Hepatitis B surface antigen was positive in 90 patients(92.8%) and cirrhosis in 84 patients(86.6%).Pringle maneuver was used routinely in these patients with clamp/unclamp cycles of 15/5 minutes.The average clamp time was 21.4±8.0 minutes.These patients were divided into 5 groups based on the CVP:group A:0-1 mmHg;B:1.1-2 mmHg;C:2.1-3 mmHg;D:3.1-4 mmHg and E:4.1-5 mmHg.The blood loss per transection area during hepatic parenchymal transection and the arterial blood gas before and after liver transection were analyzed.RESULTS:With active fluid load,a constant SBP ≥90 mmHg which was considered as optimal was maintained in 18.6% in group A(95% CI:10.8%-26.3%);39.2% in group B(95% CI:29.5%-48.9%);72.2% in group C(95% CI:63.2%-81.1%);89.7% in group D(95% CI:83.6%-95.7%);and 100% in group E(95% CI:100%-100%).The blood loss per transection area during hepatic parenchymal transection decreased with a decrease in CVP.Compared to groups D and E,blood loss in groups A,B and C was significantly less(analysis of variance test,P<0.05).Compared with the baseline,the blood oxygenation decreased significantly when the CVP was reduced.Base excess and HCO 3-in groups A and B were significantly decreased compared with those in groups C,D and E(P<0.05).CONCLUSION:In consideration of blood loss,SBP,base excess and HCO 3-,a CVP of 2.1-3 mmHg was optimal in patients undergoing partial hepatectomy for HCC. | Cheng-Xin Lin Ya Guo Wan Yee Lau Guang-Ying Zhang Yi-Ting Huang Wen-Zheng He Eric CH Lai | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 19 |
| 2 | Cep57, a NEDDl-binding pericentriolar material component, is essential for spindle pole integrity显示文摘 | Qixi Wu Runsheng He Haining Zhou Albert CH Yu Bo Zhang Junlin Teng Jianguo Chen | 2012 | Cell Research2012，22，9： | 2 |
| 3 | Connecting rigidities of various precision attachments compared with the conical crown retained telescope显示文摘 | Wang CH Lee HE Du JK et a1 | 2005 | Med Sci2005，21，1： | 1 |
| 4 | Medication adherence in patients with rheumatoid arthritis:a critical ap- praisal of the existing literature显示文摘 | van den Bemt BJ Zwikker HE van den Ende CH | 2012 | Expet Rev Clin Immunol2012，8，4： | 1 |
| 5 | Chemokines:Signal lamps for trafficking of T and B cells for development and effector function显示文摘 | Kim CH Broxmeyer HE | 1999 | J Leukoc Biol1999，65，1： | 1 |
| 6 | Efect of a lipidic extract from Lepidium meyenii on sexual behaviorin mice and rats显示文摘 | He K Kim CH | 2000 | Urology2000，55，4： | 1 |
| 7 | Neuropeptide- foundation and clinic显示文摘 | Lu CL Wang CH He C | 2000 | The Second Military Medical University2000，，： | 1 |
| 8 | Processes involved in the regulation of urease levels in Streptococcus salivarius by pH 显示文摘 | Sissons CH Perinpanayagam HE Hancock EM | 1992 | Oral Microbiol Immunol1992，7，3： | 1 |
| 9 | Bc1-2 -related protein A in endogenous and cytokine - stimulated cytoprotection in hyperoxic acute lung injury 显示文摘 | He CH Waxman AB Lee CG | 2005 | J Clin Invest2005，115，4： | 1 |
| 10 | Antioxidant activity of microwave assisted extract of Buddleia officinalis and its major active component显示文摘 | Pan YM He CH Wang HS | 2010 | Food Chem2010，121，： | 1 |
| 11 | Delay-range-dependent stability for systems with time-varying delay显示文摘 | He Y Wang Q Lin Ch | 2007 | Automatica2007，43，： | 1 |
| 12 | Interfemn-lambda mediates o- ral tolerance and inhibits antigen-specific, T-helper 2 cell-media- ted inflammation in mouse intestine显示文摘 | He SH Chen X Song CH | 2011 | Gastroenterol2011，141，1： | 1 |
| 13 | Stresses at the cervical lesion of maxillary premolar a finite element investigation显示文摘 | Lee HE L N C L Wang CH | 2002 | Journal of Dentistry2002，30，78： | 1 |
| 14 | Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells显示文摘 | Kohli L Kim CH | 2003 | J Leukoc Biol2003，73，5： | 1 |
| 15 | Protection of neonatal mice from lethal enterovirus 71 infection by maternal immunization with attenuated Salmonella enterica serovar Typhimurium expressing VP1 of enterovirus 71显示文摘 | Chiu CH Chu C He CC | 2006 | Microbes Infect2006，8，7： | 1 |
| 16 | Effect of a lipidic exlraet from Lepidium meyenii on sexual behavior in mice and rats 显示文摘 | ZHENG B L HE K KIM CH | 2000 | Urology2000，55，： | 1 |
| 17 | The capability of glucose toxicity on severe type 2 diabetes 显示文摘 | Hsieh CH Hung Y J He C T | 2005 | Endocr Res2005，31，2： | 1 |
| 18 | Synthesis and thermal properties of polythioether-based liquid crystalline polymers containing azobenzene in the side-chain显示文摘 | He CH Zhang CC Zhang OS | 2009 | Polym Int2009，58，9： | 1 |
| 19 | Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin显示文摘 | HE Q LIANG CH LIPPARD SJ | 2000 | Proc Natl Acad Sci U S A2000，97，11： | 1 |
| 20 | Plasma leptin concentration and change in bone density among elderly men and women:the Hertfordshire Cohort Study显示文摘 | Dennison EM Syddall HE Fall CH | 2004 | Calcif Tissue Int2004，74，5： | 1 |
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