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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells显示文摘 | Zhang,W Ge,W Li,CH You,SG Liao,LM Han,Q Deng,WM Zhao,RCH | 2005 | 中国生物学文摘2005，19，3： | 3 |
| 3 | Dicer, Drosha,and out- comes in patients with ovarian cancer显示文摘 | Merritt WM Lin YG Han LY | 2008 | N Engl J Med2008，359，25： | 1 |
| 4 | Allogeneic bone marrow derived flk-1+Sca-1 mesenchymal stem cells leads to stable mixed chimerism and donor-specific tolerance显示文摘 | Deng WM Han O Liao LM | 2004 | Exp Hematology2004，32，9： | 1 |
| 5 | Multi-scale structural and tensile mechanical response of annulus fibrosus to osmotic loading显示文摘 | Han WM Nerurkar NL Smith I J | 2012 | Ann Biomed Eng2012，40，7： | 1 |
| 6 | Inhibition of tobacco bacterial wilt withsulfone derivatives containing an 1,3,4~oxadiazole moiety显示文摘 | Xu WM Han FF He M | 2012 | JAgricFood Chem2012，60，： | 1 |
| 7 | Dicer, Drosha, and outcomes in patients with ovarian cancer 显示文摘 | Merritt WM Lin YG Han LY | 2008 | N Engl J Med2008，359，25： | 1 |
| 8 | Effect ofneoadjuvant chemotherapy on local advanced esophagealcancer显示文摘 | YANG R HAN JL ZHANG WM | 2014 | Chin J Clin Oncol2014，41，2： | 1 |
| 9 | Dicer, drosha, and out- comes in patients with ovarian cancer 显示文摘 | Merritt WM Lin YG Han LY | 2008 | N Engl J Med2008，359，25： | 1 |
| 10 | Dicer, Drosha, and outcomes in patients with ovarian cancer 显示文摘 | Merritt WM Lin YG Han LY | 2008 | N Engl J Med2008，359，25： | 1 |
| 11 | Recovery of a partially damaged corticospinal tract in a patient with intracerebral hemorrhage: a diffusion tensor image study 显示文摘 | Jang SH Byun WM Han BS | 2006 | Restor Neurol Neurosci2006，24，： | 1 |
| 12 | Recovery of a partially damaged corticospinal tract in a patient with intracerebral hemorrhage: a diffusion tensor image study 显示文摘 | Jang SH Byun WM Han BS | 2006 | Restorative Neurology and Neuroscience2006，24，1： | 1 |
| 13 | Mechanical ventilationduring experimental sepsis increases deposition of advancedglycation end products and myocardial inflammation显示文摘 | Martin CJ Roel PG Hans WM | 2009 | CritCare2009，13，： | 1 |
| 14 | Recovery of a partially damaged corticospinal tract in a patient with intracerebral hemorrhage: a diffusion tensor image study显示文摘 | Jang SH Byun WM Han BS | 2006 | Restor Neurol Neurosci2006，24，1： | 1 |
| 15 | Dicer, Drosha, and out- comes in patients with ovarian cancer 显示文摘 | Merritt WM Lin YG Han LY | 2008 | N Engl J Med2008，59，25： | 1 |
| 16 | Bone marrow-derived cells give rise to skin cells and regenerate skin tissue显示文摘 | Deng WM Han Q Zhao RC | 2005 | Tissue Eng2005，11，12： | 1 |
| 17 | Liposome-mediated conformation transition of DNA detected by molecular probe: methyl green显示文摘 | Huang WM Zhang ZL Han X J | 2003 | Bioelectrochemistry2003，59，12： | 1 |
| 18 | A new gliotoxin analogue from amarine-derived fungus Aspergillus fumigatus Fres显示文摘 | Zhao WY Zhu TJ Han XX Fan GT Liu HB Zhu WM Qun GuQ | | 0，，： | 1 |
| 19 | 显示文摘 | Hans WM Hutloff A Heuck C | 2000 | Eur J Immunol2000，30，4： | 1 |
| 20 | Dicer,Drosha,and outcomes in patients with ovarian cancer 显示文摘 | Merritt WM Lin YG Han LY | 2008 | N Engl J Med2008，359，25： | 1 |
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