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| 1 | Improved scoring system for the electrocardiographic diagnosis of left ventricular hypertrophy显示文摘BACKGROUND Left ventricular hypertrophy(LVH) is a common manifestation of cardiovascular disease and a risk factor for cardiovascular morbidity and mortality, but available methods for its electrocardiographic(ECG) diagnosis have limited accuracy.AIM To investigate findings associated with LVH on ECG and developed an improved system for the diagnosis of LVH.METHODS A cohort study comparing ECG data acquired within 30 days of transthoracic echocardiography(TTE) was performed. Multivariate regression analysis identified ECG findings associated with increased LV mass and mass index. A scoring system was derived and performance compared to established criteria for LVH.RESULTS Data from 5486 outpatients with TTEs and corresponding ECGs were included in the derivation cohort, 333(6.1%) of whom had LVH by TTE. In the primary regression analysis, findings associated with LVH were amplitudes of Q in V3, R in V6, S in V3, T in V6, P' in V1, P in V6, as well as R and T-axis discordance, R peak time in V6, QRS duration, weight, height, sex, and age. From this we derived a score consisting of 5 criteria, and validated it in an independent cohort of 910 patients. With a threshold of 1.5 points, sensitivity and specificity were67.9% and 81.4%, and 62.5% and 83.2% in the derivation and validation cohorts,respectively. With a threshold of 2 points, sensitivity and specificity were 42.3% and 93.0%, and 37.5% and 93.4% in these cohorts.CONCLUSIONS This score had superior sensitivity for detection of LVH by ECG while making a modest sacrifice in specificity compared to conventional criteria. | Eric D Braunstein Lori B Croft Jonathan L Halperin Steve L Liao | 2019 | World Journal of Cardiology2019，11，3： | 2 |
| 2 | Comparative immunohistochemical study of endometrioid and serous papillary carcinoma of endometrium显示文摘 | Halperin R Zehavi S Habler L | 2001 | Eur J Gynecol Oncol2001，22，2： | 1 |
| 3 | Comparative immunohistochemical study of endometrioid and serous papillary carcinoma of endometrium 显示文摘 | Halperin R Zehavi S Habler L | 2001 | Eur J Gynaecol Oncol2001，22，2： | 1 |
| 4 | Analysis of ferrate (Ⅵ) compounds and super-iron Fe (Ⅵ) battery cathodes : FTIR, ICP, titrimetric, XRD, UV vis, and electrochemical characterization显示文摘 | Licht S Naschitz V Halperin L | 2001 | Journal of Power Sources2001，101，： | 1 |
| 5 | Risk of thromboembolism in heart failure-analysis from the sudden cardiac death in heart failure trial (SCD-HeFT)显示文摘 | Freudenberger R S Hellkamp A S Halperin J L | 2007 | Circulation2007，115，20： | 1 |
| 6 | Invasive Pneumococcal Infections in Canadian Children,1991-1998:Implications for New Vaccination Strategies显示文摘 | Scheifele D Halperin S Pelletier L | 2000 | Clin Infect Dis2000，31，： | 1 |
| 7 | Comparative immunohistochemical study of endometrioid and serous papillary carcinoma of endometriurn显示文摘 | Halperin R Zehavi S Habler L | 2001 | Eur J Gynaecol Oncol2001，22，2： | 1 |
| 8 | Control of Potas- sium excretion: a Paleolithic perspective显示文摘 | Halperin M L Cheena-Dhadli S Lin S H | 2006 | Curr Opin Nephrol Hypertens2006，15，4： | 1 |
| 9 | Identifying patients at high risk for stroke despite anticoagulation:a comparison of con-temporary stroke risk stratification schemes in an anticoagu-lated atrial fibrillation cohort显示文摘 | Lip GY Frison L Halperin JL | | 0，，： | 1 |
| 10 | Toward efficient electrochemical synthesis of Fe (Ⅵ) ferrate,and super-iron battery compounds显示文摘 | Licht S Tel-Vered R Halperin L | 2004 | Journal of the Electrochemical Society2004，151，1： | 1 |
| 11 | Sorafenib in metastatic thyroid cancer显示文摘 | Capdevila J Iglesias L Halperin I | | 0，，： | 1 |
| 12 | Ultrastructure and regulation of lateralized connexin 43 in the failing heart显示文摘 | Hesketh G G Shah M H Halperin V L | 2010 | Circ Res2010，106，6： | 1 |
| 13 | Optical studies in X-irradiated high purity sodium silicate glasses显示文摘 | Mackey J H Smith H L Halperin A | 1966 | J Phys Chem Solids1966，27，： | 1 |
| 14 | An efficient approach to improve the usability of E-learning resources: The role of heuristic evaluation显示文摘 | Davids M R Chiktc U M E Halperin M L | 2013 | Advances in Physiology Education2013，，37： | 1 |
| 15 | Toward effficent electrochemical synthesis of Fe(VI)ferrate and super-iron battery compounds 显示文摘 | Tel-vered R Halperin L | 2004 | J Electrochem Soc2004，151，： | 1 |
| 16 | Lactic cacidosis emphasis on the carbon precursors and buffering of the acid load显示文摘 | MITCHELL L HALPERIN D ANTHONY L | 1985 | Am J Med Sci1985，28，4： | 1 |
| 17 | Comparativevalidation of a novel risk score for predicting bleeding risk inanticoagulated patients with atrial fibrillation : the HAS-BLED(Hypertension, Abnormal Renal/Liver Function, Stroke,Bleeding History or Predisposition, Labile INR,Elderly,Drugs/Alcohol Concomitantly) score 显示文摘 | LIP G Y FRISON L HALPERIN J L | 2011 | J Am Coll Cardiol2011，57，2： | 1 |
| 18 | 显示文摘 | Licht S Tel-Vered R Halperin L | 2002 | Electrochem Commun2002，4，： | 1 |
| 19 | Prevention of stroke in patients with atrial fibrillation: Department of Cardiology, University Hospital, Lund, Sweden显示文摘 | OLSSON S B HALPERIN J L | 2005 | Sevain Vase Med2005，5，： | 1 |
| 20 | Comparative immunohistochemical study of endometrioid and serous papillary carcinoma of endometrium显示文摘 | Halperin R Zehavi S Habler L | 2001 | Eur J Gynaecol Oncol2001，22，2： | 1 |
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