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| 1 | Improved scoring system for the electrocardiographic diagnosis of left ventricular hypertrophy显示文摘BACKGROUND Left ventricular hypertrophy(LVH) is a common manifestation of cardiovascular disease and a risk factor for cardiovascular morbidity and mortality, but available methods for its electrocardiographic(ECG) diagnosis have limited accuracy.AIM To investigate findings associated with LVH on ECG and developed an improved system for the diagnosis of LVH.METHODS A cohort study comparing ECG data acquired within 30 days of transthoracic echocardiography(TTE) was performed. Multivariate regression analysis identified ECG findings associated with increased LV mass and mass index. A scoring system was derived and performance compared to established criteria for LVH.RESULTS Data from 5486 outpatients with TTEs and corresponding ECGs were included in the derivation cohort, 333(6.1%) of whom had LVH by TTE. In the primary regression analysis, findings associated with LVH were amplitudes of Q in V3, R in V6, S in V3, T in V6, P' in V1, P in V6, as well as R and T-axis discordance, R peak time in V6, QRS duration, weight, height, sex, and age. From this we derived a score consisting of 5 criteria, and validated it in an independent cohort of 910 patients. With a threshold of 1.5 points, sensitivity and specificity were67.9% and 81.4%, and 62.5% and 83.2% in the derivation and validation cohorts,respectively. With a threshold of 2 points, sensitivity and specificity were 42.3% and 93.0%, and 37.5% and 93.4% in these cohorts.CONCLUSIONS This score had superior sensitivity for detection of LVH by ECG while making a modest sacrifice in specificity compared to conventional criteria. | Eric D Braunstein Lori B Croft Jonathan L Halperin Steve L Liao | 2019 | World Journal of Cardiology2019，11，3： | 2 |
| 2 | Anti-inflammatory effects of moxifloxacin on IL-8, IL-1beta and TNF-alpha secretion and NFkappaB and MAP-kinase activation in human monoeytes stimulated with Aspergillus fumigatus 显示文摘 | Shalit I Halperin D Haite D | 2006 | J Araimicrob Chemother2006，57，2： | 1 |
| 3 | Cold and hot denaturation ofpolysoaps显示文摘 | Leckband D E Borisov 0 V Halperin A | 1998 | Macromolecules1998，31，7： | 1 |
| 4 | Parity effects in small superconducting particles 显示文摘 | Berger S D Halperin B I | 1998 | Phys Rev B1998，58，： | 1 |
| 5 | Expression of alpha v and beta 3 integrin subunits in rat osteoclasts in sizu显示文摘 | Shinar DM Schmidt A Halperin D | 1993 | J Bone Miner Res1993，8，4： | 1 |
| 6 | Interferon - gamma and bacterial lipopolysaccharide act synergistically on human neutrophils enhancing interleukin - 8, interleukin - 1 beta, tumor necrosis factor - alpha,and interleukin- 12 p70 secretion and phagocytosis via upregulation of toll - like receptor 4 显示文摘 | Pearl - Yafe M Fabian I Halperin D | 2007 | Shock2007，27，3： | 1 |
| 7 | Constructing Two-dimensional Voronoi Diagrams via Divide-and- conquer of Envelopes in Space显示文摘 | Setter O Sharir M Halperin D | 2010 | Transactions on Computational Science IX2010，6290，： | 1 |
| 8 | One hundred years of homosexuality:and other essays on Greek love显示文摘 | HALPERIN D | 1990 | Psychology Press1990，，： | 1 |
| 9 | Thrombocytopenia after immunization of Canadian children, 1992-2001 显示文摘 | Jadavji T Scheifele D Halperin S | 2003 | Pediatr Infect Dis J2003，22，2： | 1 |
| 10 | Two freezing cycles ensure interface sterilization by cryosurgery during bone tumor resection显示文摘 | Robinson D Halperin N Nevo Z | 2001 | Cayobiology2001，43，1： | 1 |
| 11 | Pore structure of hydrating cement paste by magnetic resonance relaxation analysis and freezing显示文摘 | JEHNG J Y SPRAGUE D T HALPERIN W P | 1996 | Magn Reson Imaging1996，14，： | 1 |
| 12 | Long-term follow-up (5-20 year) after uterine ventrosuspension for chronic pelvic pain and deep dyspareunia 显示文摘 | Halperin R Padoa A Schneider D | 2003 | Gynecol Obstet Invest2003，55，4： | 1 |
| 13 | Abductor pollicis longus tendon arthroplasty of the trapezio metacarpal joint: surgical technique and results 显示文摘 | Robinson D Aghasi M Halperin N | 1991 | The Journal of Hand Surgery1991，16，3： | 1 |
| 14 | Uterine-preserving emergency surgery for cesarean scar pregnancies:another medical solution to an ratrogenie problem显示文摘 | Halperin R Schneider D Mendlovic S | 2009 | Fertil Steri12009，91，5： | 1 |
| 15 | Sternal force-displacement relationship during cardiopulmonary resuscitation显示文摘 | GRUBEN K G GUERCI A D HALPERIN H R | 1993 | J Biomech Eng1993，115，2： | 1 |
| 16 | Abortion at 18-22 weeks by laminaria dilation and evacuation 显示文摘 | Schneider D Halperin R Langer R | 1996 | Obstet Gynecol1996，88，3： | 1 |
| 17 | Invasive Pneumococcal Infections in Canadian Children,1991-1998:Implications for New Vaccination Strategies显示文摘 | Scheifele D Halperin S Pelletier L | 2000 | Clin Infect Dis2000，31，： | 1 |
| 18 | Evaluation of chromosome 12 copy number in ovarian granulosa cell tumors using interphase cytogenetics显示文摘 | Halperin D Visseher DW W'allis T | 1995 | Int J Gynecol Pathol1995，14，4： | 1 |
| 19 | Unrelated umbilical cord blood transplantation in adult patients显示文摘 | Gwynn D Long Mary Laughlin Bella Madan Joanne Kurtzberg Cristina Gasparetto Ashley Morris David Rizzieri Clayton Smith James Vredenburgh Edward C Halperin Gloria Broadwater Donna Niedzwiecki Nelson J Chao | 2003 | Biology of Blood and Marrow Transplantation2003，，： | 1 |
| 20 | Complications of circumcision in male neonates, infants and children: a systematic review显示文摘 | Weiss H A Larke N Halperin D | 2010 | BMC Urol2010，10，2： | 1 |
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