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| 1 | Positioning accuracy assessment for the 4GEO/5IGSO/2MEO constellation of COMPASS显示文摘Determined to become a new member of the well-established GNSS family,COMPASS(or BeiDou-2) is developing its capabilities to provide high accuracy positioning services.Two positioning modes are investigated in this study to assess the positioning accuracy of COMPASS' 4GEO/5IGSO/2MEO constellation.Precise Point Positioning(PPP) for geodetic users and real-time positioning for common navigation users are utilized.To evaluate PPP accuracy,coordinate time series repeatability and discrepancies with GPS' precise positioning are computed.Experiments show that COMPASS PPP repeatability for the east,north and up components of a receiver within China's Mainland is better than 2 cm,2 cm and 5 cm,respectively.Apparent systematic offsets of several centimeters exist between COMPASS precise positioning and GPS precise positioning,indicating errors remaining in the treatments of COMPASS measurement and dynamic models and reference frame differences existing between two systems.For common positioning users,COMPASS provides both open and authorized services with rapid differential corrections and integrity information available to authorized users.Our assessment shows that in open service positioning accuracy of dual-frequency and single-frequency users is about 5 m and 6 m(RMS),respectively,which may be improved to about 3 m and 4 m(RMS) with the addition of differential corrections.Less accurate Signal In Space User Ranging Error(SIS URE) and Geometric Dilution of Precision(GDOP) contribute to the relatively inferior accuracy of COMPASS as compared to GPS.Since the deployment of the remaining 1 GEO and 2 MEO is not able to significantly improve GDOP,the performance gap could only be overcome either by the use of differential corrections or improvement of the SIS URE,or both. | ZHOU ShanShi CAO YueLing ZHOU JianHua HU XiaoGong TANG ChengPan LIU Li GUO Rui HE Feng CHEN JunPing WU Bin | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，12： | 31 |
| 2 | Mapping the hotspots and coldspots of ecosystem services in conservation priority setting显示文摘空间明确地热点和 coldspots 印射是在将保存放为生态系统服务(ES ) 的优先级的一个重要连接。然而,很少研究都没识别并且测试了他们的 ES 热点和 coldspots 的紧密和效率,它可以削弱生态的保存的有效性。在这学习,基于 RUSLE 模型和 Getis-Ord 官方补给 * 统计,我们确定了年度土壤保存服务(SC ) 的变化并且从 2000 ~ 2013 在中国的 Shaanxi 省识别了统计上重要的热点和 coldspots。结果显示那, 1 ) 有高 SC 的区域也介绍了一个显著地增加的趋势,当有低 SC 的区域仅仅稍微变化了时;2 ) SC 热点和 coldspots 证明热点主要是的明显的空间 differentiationthe 空间地在南部的 Shaanxi 聚集了,当 coldspots 主要在 Guanzhong 盆和沙多风的高原被散布时;并且 3 ) 识别热点有提供 SC 的最高的能力,与提供的 29.6% 全部的区域, 59.7% 总数满足。相反, coldspots 占据了 46.3% 全部的区域,但是仅仅提供了 17.2% 全部的 SC。除了保存单个 ES, Getis-Ord 官方补给 * 统计方法能也帮助为保存多重 ES 和生物多样性识别多功能的优先级区域。 | LI Yingjie ZHANG Liwei YAN Junping WANG Pengtao HU Ningke CHENG Wei FU Bojie | 2017 | Journal of Geographical Sciences2017，27，6： | 19 |
| 3 | Continuous unidirectional solidification of QAl9-4 Cu-Al alloy显示文摘A continuous unidirectional solidification equipment with the advantages of electric slag remelting, induction heating, continuous casting and unidirectional solidification was built to study the QAl9 4 Cu Al alloy. The results show that the electro slag induction continuous unidirectional solidification process can be used for the steady continuous unidirectional solidification of QAl9 4, and revitalizes the down pulling continuous unidirectional solidification process; that the temperature distribution in the mold wall reflects that of the molten metal in the mold, thus the temperature distribution in the mold wall can be used to control the electric slag induction continuous unidirectional solidification process; and that the mutual matching of the technological parameters is the key to stabilize the solidification process. | Chang Guowei(常国威) Yuan Junping(袁军平) Wang Zidong(王自东) Wu Chunjing(吴春京) Hu Hanqi(胡汉起) Miao Zhimin(苗治民) | 1999 | 中国有色金属学会会刊:英文版1999，9，3： | 8 |
| 4 | Mutation profile and its correlation with clinicopathology in Chinese hepatocellular carcinoma patients显示文摘Background:Hepatocellular carcinoma(HCC)is one of the most common causes of cancer worldwide.Although many studies have focused on oncogene characteristics,the genomic landscape of Chinese HCC patients has not been fully clarified.Methods:A total of 165 HCC patients,including 146 males and 19 females,were enrolled.The median age was 55 years(range,27-78 years).Corresponding clinical and pathological information was collected for further analysis.A total of 168 tumor tissues from these patients were selected for next-generation sequencing(NGS)-based 450 panel gene sequencing.Genomic alterations including single nucleotide variations(SNV),short and long insertions and deletions(InDels),copy number variations,and gene rearrangements were analyzed.Tumor mutational burden(TMB)was measured by an algorithm developed in-house.The top quartile of HCC was classified as TMB high.Results:A total of 1,004 genomic alterations were detected from 258 genes in 168 HCC tissues.TMB values were identified in 160 HCC specimens,with a median TMB of 5.4 Muts/Mb(range,0-28.4 Muts/Mb)and a 75%TMB of 7.7 Muts/Mb.The most commonly mutated genes were TP53,TERT,CTNNB1,AXIN1,RB1,TSC2,CCND1,ARID1A,and FGF19.SNV was the most common mutation type and C:G>T:A and guanine transformation were the most common SNVs.Compared to wild-type patients,the proportion of Edmondson grade III-IV and microvascular invasion was significantly higher in TP53 mutated patients(P<0.05).The proportion of tumors invading the hepatic capsule was significantly higher in TERT mutated patients(P<0.05).The proportion of Edmondson grade I-II,alpha fetoprotein(AFP)<25μmg/L,and those without a history of hepatitis B was significantly higher in CTNNB1 mutated patients(P<0.05).CTNNB1 mutations were associated with TMB high in HCC patients(P<0.05).Based on correlation analysis,the mutation of TP53 was independently correlated with microvascular invasion(P=0.002,OR=3.096)and Edmondson grade III-IV(P=0.008,OR=2.613).The mutation of TERT was independently correlated with tumor invasion of the liver capsule(P=0.001,OR=3.030),and the mutation of CTNNB1 was independently correlated with AFP(<25μmg/L)(P=0.009,OR=3.414).Conclusions:The most frequently mutated genes of HCC patients in China were TP53,TERT,and CTNNB1,which mainly lead to the occurrence and development of HCC by regulating the P53 pathway,Wnt pathway,and telomere repair pathway.There were more patients with microvascular invasion and Edmondson III-IV grade in TP53 mutated patients and more patients with hepatic capsule invasion in TERT mutated patients,while in CTNNB1 mutated patients,there were more patients with Edmondson I-II grade,AFP<25μmg/L,and a non-hepatitis B background.Also,the TMB values were significantly higher in CTNNB1 mutated patients than in wild type patients. | Shuo Wang Huasheng Shi Tao Liu Manjiang Li Sanshun Zhou Xuan Qiu Zusen Wang Weiyu Hu Weidong Guo Xiaoqian Chen Honglin Guo Xiaoliang Shi Junping Shi Yunjin Zang Jingyu Cao Liqun Wu | 2021 | Hepatobiliary Surgery and Nutrition2021，10，2： | 8 |
| 5 | Ambulatory blood pressure profile and stroke recurrence显示文摘Objectives To establish a new ambulatory blood pressure(ABP)parameter(24-hour ABP profile)and evaluated its performance on stroke outcome in ischaemic stroke(IS)or transient ischaemic attack(TIA)patients.Methods The prospective cohort consisted of 1996 IS/TIA patients enrolled for ABP monitoring and a 3-month follow-up for stroke recurrence as outcome.Profile groups of systolic blood pressure(SBP)were identified via an advanced functional clustering method,and the associations of the profile groups and conventional ABP parameters with stroke recurrence were examined in a Cox proportional hazards model.Results Three discrete profile groups(n=604,781 and 611 in profiles 1,2 and 3,respectively)in 24-hour ambulatory SBP were identified.Profile 1 resembled most to the normal diurnal blood pressure pattern;profile 2 also dropped at night,but climbed earlier and with higher morning surge;while profile 3 had sustained higher nocturnal SBP without significant nocturnal SBP decline.The incidence of stroke recurrence was 2.9%,3.9%and 5.5%in profiles 1,2 and 3,respectively.After adjustment for covariates,profile 3 was significantly associated with higher risk of stroke recurrence with profile 1 as reference(HR 1.76,95%CI:1.00 to 3.09),while no significant difference was observed between profiles 2 and 1(HR 1.22,95%CI:0.66 to 2.25).None of conventional ABP parameters showed significant associations with the outcome.Conclusions Ambulatory 24-hour SBP profile is associated with short-term stroke recurrence.Profiles of ABP may help improve identification of stroke recurrence by capturing the additive effects of individual ABP parameters. | Jie Xu Fei Jiang Anxin Wang Hui Zhi Yuan Gao Junping Tian Jinglin Mo Zimo Chen An-Ding Xu Benyan Luo Bo Hu Yuqing Zhang Xingquan Zhao Yilong Wang Hao Li Haipeng Shen Yongjun Wang | 2021 | Stroke & Vascular Neurology2021，6，3： | 3 |
| 6 | Robust, healable and hydrophobically recoverable polydimethylsiloxane based supramolecular material with dual-activate hard segment显示文摘In this paper, a novel dual-activate hard segment strategy is proposed for the fabrication of polydimethylsiloxane(PDMS) based supramolecular polymer(PDMS-PDITC-IPDI). The unique design endows the PDMS-PDITC-IPDI with high toughness(43.1–24.5 MJ/m^(3)), tensile strength(11.3–6.6 MPa) and elongation at break(730%–615%), and the mechanical properties and dynamic property can be regulated by varying degrees of hard segment activation. Moreover, the PDMS-PDITC-IPDI polymers exhibit excellent self-recovery property during successive loading-unloading processes. Additionally, both wettability damage caused by O2 plasma treatment and mechanical damage can be healed by simple heating, showing good hydrophobic recovery and selfhealability. Taking advantages of merits of the PDMS-PDITC-IPDI, the applications of the material as recyclable adhesive and 3D printing material are also investigated. | LV Chi QI YuHao HU RuoFei ZHENG JunPing | 2021 | Science China(Technological Sciences)2021，64，2： | 2 |
| 7 | Microbiome technology empowers the development of traditional Chinese medicine显示文摘Application of microbiome technology to traditional Chinese medicine (TCM). Microbiome refers to the integration of composition, genetic information and bio-function of all microbial species under a specific environment. | Hongtao Liu Junping Zheng Hsin-Chih Lai Baifei Hu Lin Zhu Elaine Lai-Han Leung Hong Wei | 2020 | Science China(Life Sciences)2020，63，11： | 2 |
| 8 | Sophocarpine and matrine inhibit the production of TNF-α and IL-6 in murine macrophages and prevent cachexia-related symptoms induced by colon26 adenocarcinoma in mice显示文摘 | Yuefan Zhang Shaozhan Wang Yuanyuan Li Zhenyu Xiao Zhenlin Hu Junping Zhang | 2008 | International Immunopharmacology2008，，13： | 2 |
| 9 | Structure and thermal stability of PMMA/MMT nanocomposites as denture base material显示文摘 | Xiang Wang Qiang Su Yumei Hu Chuanzeng Wang Junping Zheng | 2014 | Journal of Thermal Analysis and Calorimetry2014，，2： | 1 |
| 10 | The regulation of hematopoietic stem cell fate in the context of radiation显示文摘Hematopoietic system is one of the main target organs of irradiation injury.Exposure to radiation can cause acute myelosuppression and long-term hematopoietic injury due to the direct and indirect damage of hematopoietic stem cells(HSCs)that can self-renew and differentiate into all types of blood cells.So far,many factors in the modulation of HSC biology at steady status have been revealed,while how to orchestrate HSCs in the context of radiation has not been well established.Recently,an increasing number of studies focus on the underlying mechanisms involved in regulating HSC fate after radiation exposure by affecting DNA damage response(DDR),including DNA-damage repair,cell-cycle arrest,apoptosis and senescence,or bone marrow(BM)microenvironment.In this review,we summarize recent findings on intrinsic and extrinsic factors in the regulation of HSC fate after radiation exposure,which may further deepen our understanding of the radioprotection of HSCs. | Yukai Lu Mengjia Hu Zihao Zhang Yan Qi Junping Wang | 2020 | Radiation Medicine and Protection2020，1，1： | 1 |
| 11 | Impact of Freeze-Thaw Cycles on Compressive Characteristics of Asphalt Mixture in Cold Regions显示文摘Low average temperature, large temperature difference and continual freeze-thaw(F-T) cycles have significant impacts on mechanical property of asphalt pavement. F-T cycles test was applied to illustrate the mixtures' compressive characteristics. Exponential model was applied to analyze the variation of compressive characteristics with F-T cycles; Loss ratio model and Logistic model were used to present the deterioration trend with the increase of F-T cycles. ANOVA was applied to show the significant impact of F-T cycles and asphaltaggregate ratio. The experiment results show that the compressive strength and resilient modulus decline with increasing F-T cycles; the degradation is sharp during the initial F-T cycles, after 8 F-T cycles it turns to gentle. ANOVA results show that F-T cycles, and asphalt-aggregate ratio have significant influence on the compressive characteristics. Exponential model, Loss ratio model and Logistic model are significantly fitting the test data from statistics view. These models well reflect the compressive characteristics of asphalt mixture degradation trend with increasing F-T cycles. | 司伟 LI Ning 马骉 REN Junping WANG Hainian HU Jian | 2015 | Journal of Wuhan University of Technology(Materials Science)2015，30，4： | 1 |
| 12 | Synthesis and Biological Evaluation of Novel Uracil and 5-Fluorouracil-l-yl Acetic Acid-Colchicine Conjugate显示文摘 | SHEN Lihong HU Junping WANG Haixian WANG Aibing LAI Yisheng KANG Yanhui | 2015 | Chemical Research in Chinese Universities2015，31，3： | 1 |
| 13 | A time- based cluster -head selection algorithm for LEACH显示文摘 | Hu Junping Jin Yuhui Dou Liang | 2008 | IEEE2008，，8： | 1 |
| 14 | Matrine Inhibits Infiltration of the Inflammatory Gr 1 hi Monocyte Subset in Injured Mouse Liver through Inhibition of Monocyte Chemoattractant Protein-1显示文摘 | Duo Shi Jinjin Zhang Lei Qiu Jianzhong Li Zhenlin Hu Junping Zhang Evan Paul Cherniack | 2013 | Evidence-Based Complementary and Alternative Medicine2013，，： | 1 |
| 15 | A highly selective and sensitive dopamine and uric acid biosensor fabricated with functionalized ordered mesoporous carbon and hydrophobic ionic liquid显示文摘 | Junping Dong Yanyan Hu Shenmin Zhu Jiaqiang Xu Yinjuan Xu | 2010 | Analytical and Bioanalytical Chemistry2010，，5： | 1 |
| 16 | Human-machine augmented intelligence:research and applications显示文摘Current research on artificial intlligence(Al)has been entering a new era,with AI technologies and Al-enabled applications emerging in almost every aspect of human life.Meanwhile,avoiding the risk caused by limitations of AI technologies has becomea grand challenge.The main idea of human-machine augmented intelligence(HAlI)is to adopt the role of humans or to embed human-like cognitive abilities into intelligent machines.Increasing atention and efforts from academia,industry,and governments are attracted by the HAl idea,whose effects are far-reaching. | Jianru XUE Bin HU Lingxi LI Junping ZHANG | 2022 | Frontiers of Information Technology & Electronic Engineering2022，23，8： | 1 |
| 17 | A highly selective and sensitive dopamine and uric acid biosensor fabricated with functionalized ordered mesoporous carbon and hydrophobic ionic liquid 显示文摘 | Dong Junping Hu Yanyan Zhu Shenmin etc | 2010 | Analytical and Bioanalytical Chemistry2010，396，5： | 1 |
| 18 | The approximate age of the planation surface and the incision of the Yellow River显示文摘 | Baotian Pan Zhenbo Hu Junping Wang Jef Vandenberghe Xiaofei Hu Yuhua Wen Qiong Li Bo Cao | 2010 | Palaeogeography Palaeoclimatology Palaeoecology2010，，： | 1 |
| 19 | Renaming NAFLD to MAFLD:Advantages and Potential Changes in Diagnosis,Pathophysiology,Treatment,and Management显示文摘In recent years,with the increasing incidence of obesity and other metabolic diseases,the prevalence of non-alcoholic fatty liver disease(NAFLD)has increased and it has become a major health problem affecting more than one quarter of the world’s population.Recently,experts reached a consensus that NAFLD does not reflect the current knowledge,and metabolic dysfunctionassociated fatty liver disease(MAFLD)was suggested as a more appropriate term.MAFLD is not just a simple renaming of NAFLD.The definition of MAFLD allows a patient to have dual(or more)etiologies for their liver disease,which will help to exclude more heterogeneous patients.In this review,we introduce the significant differences between the definitions of NAFLD and MAFLD.In addition,we also describe the advantages of the term MAFLD in the pathophysiology,therapy,and patient management. | Fajuan Rui Hongli Yang Xinyu Hu Qi Xue Yayun Xu Junping Shi Jie Li | 2022 | Infectious Microbes & Diseases2022，4，2： | 0 |
| 20 | Novel magnetic field computation model in pattern classification显示文摘Field computation, an emerging computation technique,has inspired passion of intelligence science research. A novel field computation model based on the magnetic field theory is constructed. The proposed magnetic field computation(MFC) model consists of a field simulator, a non-derivative optimization algorithm and an auxiliary data processing unit. The mathematical model is deduced and proved that the MFC model is equivalent to a quadratic discriminant function. Furthermore, the finite element prototype is derived, and the simulator is developed, combining with particle swarm optimizer for the field configuration. Two benchmark classification experiments are studied in the numerical experiment, and one notable advantage is demonstrated that less training samples are required and a better generalization can be achieved. | Feng Pan Xiaoting Li Ting Long Xiaohui Hu Tingting Ren Junping Du | 2013 | Journal of Systems Engineering and Electronics2013，24，5： | 0 |
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