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| 1 | Potential toxic risk of heavy metals from sediment of the Pearl River in South China显示文摘Based on the monitoring of five heavy metal elements in the surface sediments of the Pearl River in South China, potential toxicity of the heavy metals was assessed using consensus-based sediment quality guidelines (SQGs) method and geo-accumulation (Igeo) index method. The monitoring results showed the heavy metal concentrations were significantly and positively correlated with each other, demonstrating a common trend in variation of concentration in the surface sediments. The assessment using the consensus-based SQGs method showed the potential toxicity of Cu was the highest, and Cd was the lowest. The evaluation based on mean probable effect concentration (PEC) quotient showed the region was seriously polluted with high toxicity heavy metals. Correlation analysis revealed a significant and positive correlation between the mean PEC quotient and the average of Igeo with a correlation coefficient of 0.926 (n = 23, P < 0.01). In conclusion, the consensus-based SQGs and mean PEC quotient are applicable to assess potential toxicity risks of heavy metals in freshwater sediments in the Pearl River. | NIU Hongyi DENG Wenjing WU Qunhe CHEN Xingeng | 2009 | Journal of Environmental Sciences2009，21，8： | 52 |
| 2 | Liutex (vortex) core definition and automatic identification for turbulence vortex structures显示文摘As a milestone research in vortex identification(VI),the physical quantity of Liutex,including its forms of scalar,vector and tensor,was systematically explored and rigorously obtained as the third-generation(3G)of the vortex definition and identification methods distinguished from the first generation(1G)by vorticity and the second generation(2G)by the vortex identification(VI)criteria solely dependent on the velocity gradient tensor eigenvalues.Based on these findings,the vortex-core lines were abstracted from the well-defined Liutex,and for the first time,were automatically generated and massively visualized using computer.The distinctive characteristics of these vortex cores with the intriguing threshold-independency make them be the uniquely appropriate entity to represent and to depict the vortex structures in turbulence.The letter made use of the DNS data for the natural transition in a zero-pressure gradient flat-plate(Type-A turbulent boundary layer(TBL))and the fully-developed turbulence in a square annular duct(Type-B TBL)to demonstrate the vortex structure represented by the vortex-core lines.The 3G VI approach based on the vortex-core lines is capable of profoundly uncovering the vortex natures.Moreover,the capability of automatically identifying the vortex cores and massively visualizing the large number of vortex-core behaviors in a transient way will enable the fluid-mechanics and other related-science communities to step into a new era to explore the intrinsic natures of the centennial puzzle of turbulence and other vortex-related phenomena in future. | Hongyi Xu Xiao-shu Cai Chaoqun Liu | 2019 | Journal of Hydrodynamics2019，31，5： | 21 |
| 3 | Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma显示文摘Esophageal squamous cell carcinoma(ESCC)is a poor-prognosis cancer type with limited understanding of its molecular etiology.Using 508 ESCC genomes,we identified five novel significantly mutated genes and uncovered mutational signature clusters associated with metastasis and patients’outcomes.Several functional assays implicated that NFE2L2 may act as a tumor suppressor in ESCC and that mutations in NFE2L2 probably impaired its tumor-suppressive function,or even conferred oncogenic activities.Additionally,we found that the NFE2L2 mutations were significantly associated with worse prognosis of ESCC.We also identified potential noncoding driver mutations including hotspot mutations in the promoter region of SLC35E2 that were correlated with worse survival.Approximately 5.9%and 15.2%of patients had high tumor mutation burden or actionable mutations,respectively,and may benefit from immunotherapy or targeted therapies.We found clinically relevant coding and noncoding genomic alterations and revealed three major subtypes that robustly predicted patients’outcomes.Collectively,we report the largest dataset of genomic profiling of ESCC useful for developing ESCC-specific biomarkers for diagnosis and treatment. | Yongping Cui Hongyan Chen Ruibin Xi Heyang Cui Yahui Zhao Enwei Xu Ting Yan Xiaomei Lu Furong Huang Pengzhou Kong Yang Li Xiaolin Zhu Jiawei Wang Wenjie Zhu Jie Wang Yanchun Ma Yong Zhou Shiping Guo Ling Zhang Yiqian Liu Bin Wang Yanfeng Xi Ruifang Sun Xiao Yu Yuanfang Zhai Fang Wang Jian Yang Bin Yang Caixia Cheng Jing Liu Bin Song Hongyi Li Yi Wang Yingchun Zhang Xiaolong Cheng Qimin Zhan Yanhong Li Zhihua Liu-Show | 2020 | Cell Research2020，30，10： | 19 |
| 4 | A "green pathway" different from simple diffusion in soft matter: Fast molecular transport within micro/nanoscale multiphase porous systems显示文摘 | Jiantao Feng Fang Wang Xinxiao Han Zhuo Ao Quanmei Sun Wenda Hua Peipei Chen Tianwei Jing Hongyi Li Dong Han | 2014 | Nano Research2014，7，3： | 18 |
| 5 | Liutex theoretical system and six core elements of vortex identification显示文摘The third-generation vortex identification method of Liutex(previously called Rortex)was introduced by the team led by Prof.Chaoqun Liu from University of Texas at Arlington to mathematically extract the rigid rotation part from the fluid motion,and thus to define and visualize vortices.Unlike the vorticity-based first generation and the scalar-valued second generation,Q,λ2,Δandλci methods for example,the Liutex vector provides a unique,mathematical and systematic way to define vortices and visualize vortical structures from multiple perspectives without ambiguity.In this article,we summarize the recent developments of the Liutex framework and discuss the Liutex theoretical system including its existence,uniqueness,stability,Galilean invariance,locality and globality,decomposition in tensor and vector forms,Liutex similarity in turbulence,and multiple Liutex-based vortex visualization methods including Liutex lines,Liutex magnitude iso-surfaces,Liutex-Ωmethod,and Liutex core line method,etc..Thereafter,the six core elements of vortex identification,including(1)absolute strength,(2)relative strength,(3)local rotational axis,(4)vortex rotation axes,(5)vortex core size,(6)vortex boundary,are used as touchstones against which the Liutex vortex identification system is examined.It is demonstrated with illustrative examples that the Liutex system is able to give complete and precise information of all six core elements in contrast to the failure and inaccuracy of the first and second-generation methods.The important concept that vorticity cannot represent vortex and the superiority of the Liutex system over previous methods are reiterated and stated in appropriate places throughout the paper.Finally,the article concludes with future perspectives,especially the application of the Liutex system in studying turbulence mechanisms encouraged by the discovery of Liutex similarity law.As a newly defined physical quantity,Liutex may open a door for quantified vortex and turbulence research including Liutex(vortex)dynamics and lead the community out of the shadow of turbulence research which traditionally relies on observations,graphics,assumptions,hypotheses,and other qualitative analyses.An optimistic projection is that the Liutex system could be critical to investigation of the vortex dynamics in applications from hydrodynamics,aerodynamics,oceanography,meteorology,etc.and to research of the generation,sustenance,modelling and controlling of turbulence. | Yi-qian Wang Yi-sheng Gao Hongyi Xu Xiang-rui Dong Jian-ming Liu Wen-qian Xu Meng-long Chen Chaoqun Liu | 2020 | Journal of Hydrodynamics2020，32，2： | 17 |
| 6 | Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing显示文摘单个房间的定序是为描出的一个强大的工具为个性化的癌症管理的同种细胞的关系和识别关键司机基因。这里,我们执行了结肠癌的一个盒子的单个房间的定序的分析。人口遗传分析在肿瘤房间人口识别了二独立克隆。主要肿瘤克隆作为早 oncogenic 事件怀有 APC 和 TP53 变化,而次要的克隆包含了优势的 CDC27 和 PABPC1 变化。在这二克隆的次要的克隆支持的 APC 和 TP53 变化的缺席从二细胞的起源被导出。体的变化等位基因频率系列的检查另外 21 个整个织物的定序 exome 的盒子在结肠癌揭示了同种细胞的起源的异质。下次,我们识别了在单个房间的水平显示出变化的高频率,但是在人口水平展出了低流行的变异的基因 SLC12A5。变异的 SLC12A5 的功能的描述在结肠癌揭示了它的潜在的 oncogenic 效果。我们的学习在单个房间的水平支持提供第一条 exome 宽的证据那结肠癌能具有 biclonal 起源,并且建议在一个队的低流行的变化可以也在单个水平起重要 protumorigenic 作用。 | Chang Yu Jun Yu Xlaotlan Yao Wllham KK Wu Youyong Lu Senwel Tang Xiangchun Li Li Bao Xiaoxing Li Yong Hou Renhua Wu Min Jian Ruoyan Chen Fan Zhang Lixia Xu Fan Fan Jun He Qiaoyi Liang Hongyi Wang Xueda Hu Minghui He Xiang Zhang Hancheng Zheng Qibin Li Hanjie Wu Yan Chen Xu Yang Shida Zhu Xun Xu Huanming Yang Jian Wang Xiuqing Zhang Joseph JY Sung Yingrui Li Jun Wang | 2014 | Cell Research2014，，6： | 16 |
| 7 | Magnetic spin–orbit interaction of light显示文摘We study the directional excitation of optical surface waves controlled by the magnetic field of light.We theoretically predict that a spinning magnetic dipole develops a tunable unidirectional coupling of light to transverse electric(TE)polarized Bloch surface waves(BSWs).Experimentally,we show that the helicity of light projected onto a subwavelength groove milled into the top layer of a 1D photonic crystal(PC)controls the power distribution between two TE-polarized BSWs excited on both sides of the groove.Such a phenomenon is shown to be solely mediated by the helicity of the magnetic optical field,thus revealing a magnetic spin-orbit interaction of light.Remarkably,this magnetic optical effect is clearly observed via a near-field coupler governed by an electric dipole moment:it is of the same order of magnitude as the electric optical effects involved in the coupling.This opens up new degrees of freedom for the manipulation of light and offers desirable and novel opportunities for the development of integrated optical functionalities. | Mengjia Wang Hongyi Zhang Tatiana Kovalevich Roland Salut Myun-Sik Kim Miguel Angel Suarez Maria-Pilar Bernal Hans-Peter Herzig Huihui Lu Thierry Grosjean | 2018 | Light(Science & Applications)2018，7，1： | 15 |
| 8 | Valley excitons in two-dimensional semiconductors显示文摘Monolayer group-VIB transition-metal dichalcogenides have recently emerged as a new class of semiconductors in the two-dimensional limit. he atractive properties include the visible range direct band gap ideal for exploring optoelectronic applications; the intriguing physics associated with spin and valley pseudospin of carriers which implies potentials for novel electronics based on these internal degrees of freedom; the exceptionally strong Coulomb interaction due to the two-dimensional geometry and the large efective masses. he physics of excitons, the bound states of electrons and holes, has been one of the most actively studied topics on these two-dimensional semiconductors, where the excitons exhibit remarkably new features due to the strong Coulomb binding, the valley degeneracy of the band edges and the valley-dependent optical selection rules for interband transitions. Here, we give a brief overview of the experimental and theoretical indings on excitons in two-dimensional transition-metal dichalcogenides,with focus on the novel properties associated with their valley degrees of freedom. | Hongyi Yu Xiaodong Cui Xiaodong Xu Wang Yao | 2015 | National Science Review2015，2，1： | 15 |
| 9 | Adaptive event-triggered control for a class of nonlinear systems with periodic disturbances显示文摘This paper investigates the adaptive event-triggered control problem for a class of nonlinear systems subject to periodic disturbances. To reduce the communication burden, a reliable relative threshold strategy is proposed. Fourier series expansion and radial basis function neural network are combined into a function approximator to model suitable time-varying disturbed function of known periods in strict-feedback systems. By combining the Lyapunov stability theory and the backstepping technique, the proposed adaptive control approach ensures that all the signals in the closed-loop system are bounded, and the tracking error can be regulated to a compact set around zero in finite time. Finally, simulation results are presented to verify the effectiveness of the theoretical results. | Hui MA Hongyi LI Renquan LU Tingwen HUANG | 2020 | Science China(Information Sciences)2020，63，5： | 14 |
| 10 | Cerebral small vessel disease or intracranial large vessel atherosclerosis may carry different risk for future strokes显示文摘Background The effect of cerebral small vessel disease(CSVD)and intracranial arterial stenosis(ICAS)on stroke outcomes remains unclear.Methods Data of 1045 patients with minor stroke or transient ischaemic attack(TIA)were obtained from 45 sites of the Clopidogrel in High-Risk Patients with Acute Non-disabling Cerebrovascular Events(CHANCE)trial.We assessed the associations of burdens of CSVD and ICAS with new strokes and bleeding events using multivariate Cox regression models and those with modified Rankin Scale(mRS)scores using ordinal logistic regression models.Results Among the 1045 patients,CSVD was present in 830 cases(79.4%)and ICAS in 460(44.0%).Patients with>1 ICAS segment showed the highest risk of new strokes(HR 2.03,95%CI 1.15 to 3.56,p=0.01).No association between CSVD and the occurrence of new strokes was found.The presence of severe CSVD(common OR(cOR)2.01,95%CI 1.40 to 2.89,p<0.001)and>1 ICAS segment(cOR 2.15,95%CI 1.57 to 2.93,p<0.001)was associated with higher mRS scores.Severe CSVD(HR 10.70,95%CI 1.16 to 99.04,p=0.04),but not ICAS,was associated with a higher risk of bleeding events.Six-point modified CSVD score improved the predictive power for bleeding events and disability.Interpretation CSVD is associated with more disability and bleeding events,and ICAS is associated with an increased risk of stroke and disability in patients with minor stroke and TIA at 3 months.CSVD and ICAS may represent different vascular pathologies and play distinct roles in stroke outcomes. | Huimin Chen Yuesong Pan Lixia Zong Jing Jing Xia Meng Yuyuan Xu Hongyi Yan Xingquan Zhao Liping Liu Hao Li S Claiborne Johnston Yongjun Wang Yilong Wang | 2020 | Stroke & Vascular Neurology2020，5，2： | 13 |
| 11 | Composition, origin and weathering process of surface sediment in Kumtagh Desert, Northwest China显示文摘Kumtagh 沙漠是在中国的八最大的沙漠之一,但是因为存取的困难,以前糟糕调查我们的学科交差的学习。在这份报纸, 33 件代表性的表面沉积样品从在实验室荒芜、分析的 Kumtagh 被收集获得重矿物质部件和 geochemical 元素内容。结果证明重矿物质的各种各样的类型在这些样品是在场的,与绿帘石和角闪石的高水平。Si 和艾尔收起化学作文的大部分。与上面的大陆人外壳(UCC ) 的 geochemical 元素的平均作文相比,除了 Si 和 Ca,所有元素被弄空到某个度;Fe, Mg, Ca, P, Ti 和 Mn 在他们的内容有高关联系数。矿物质和 Kumtagh 荒芜的沉积的 geochemical 作文在 Altyn Tagh 山脉和 Taklamakan 沙漠的附近与 Altyn Tagh 山脉,和冲积/洪水的扇子的表面沉积的岩石的有类似,显示 Kumtagh 荒芜的沉积的一主要来源位于 Altyn Tagh 山脉。在 Aqik 山谷和 Shule 河的更低的活动范围的冲积沉积物和湖沉积是容易的被侵蚀并且搬运由强壮在东北弯屈进 Kumtagh 沙漠,形成沙漠的另一来源扔。一张 A-CN-K 第三的图证明由 Na 和 K 的损失捱过的弱度化学药品发生在这些沉积,而 A-CNK-FM 第三的图建议 Fe 和 Mg 经历了重要化学区别。物理捱过过程为 mafic 矿物质在好粒子引起容易的侵蚀和丰富,这样粗糙的荒芜的沙粒子能相对在 Fe 和 Mg 被弄空。在经历不太化学的捱过的干旱区域的沉积的矿物质和 geochemical 作文被物理捱过主要影响。 | XU Zhiwei LU Huayu ZHAO Cunfa WANG Xianyan SU Zhizhu WANG Zhenting LIU Hongyi WANG Lixin LU Qi | 2011 | Journal of Geographical Sciences2011，21，6： | 13 |
| 12 | High lake levels on Alxa Plateau during the Late Quaternary显示文摘Field investigations including lake shoreline measurement and 14 C chronology have been carried out on the Alxa Plateau to better understand the formation and evolution of the high lake levels in northwest China during the late Pleistocene.Comprehensive field investigations show that there are at least ten shorelines at different elevations at Juyan Lake,at least four on the northwest side of the Jilantai Salt Lake,and nine shorelines and one terrace on the northeast margin of Zhuye Lake.Stratigraphic correlations and chronological evidence indicate that the paleo-lakes have the highest lake levels in Marine Isotope Stage (MIS) 3.Though the optically stimulated luminescence (OSL) results which have been reported by some scholars do not support this view,the fact that the paleo-lakes have the highest lake levels in MIS 3 can not be denied.Differences between OSL and 14 C results from this work might indicate that high lake levels existed on the Alxa Plateau during two different periods.It also suggests that the high lake levels may exist in both MIS 5 and early MIS 3.This paper also provides the basic hydrological information for further water resources research in this arid region. | WANG NaiAng LI ZhuoLun CHENG HongYi LI Yu HUANG YinZhou | 2011 | Chinese Science Bulletin2011，56，17： | 12 |
| 13 | Heterogeneous oxidation of cyclohexanone catalyzed by TS-1:Combined experimental and DFT studies显示文摘 | Changjiu Xia Long Ju Yi Zhao Hongyi Xu Bin Zhu Feifei Gao Min Lin Zhenyu Dai Xiaodong Zou Xingtian Shu | 2015 | 催化学报2015，36，6： | 11 |
| 14 | Association of elevated hs-CRP and multiple infarctions with outcomes of minor stroke or TIA: subgroup analysis of CHANCE randomised clinical trial显示文摘Background and purpose The relationship of high-sensitive C-reactive protein(hs-CRP)levels and infarction numbers with the prognosis of stroke is uncertain.This study evaluated the association of different hs-CRP levels and infarction numbers with the prognosis of acute minor ischaemic stroke or transient ischaemic attack(TIA).Methods A subset of 807 patients with both hs-CRP measurement and baseline MRI was included from the Clopidogrel in High-risk Patients with Acute Non-disabling Cerebrovascular Events trial.The primary efficacy outcome was the occurrence of an ischaemic stroke at the 1-year follow-up.Infarction numbers were classified as multiple acute infarctions(MAIs),single acute infarction and no acute infarction(NAI).The association between different hs-CRP levels with different infarction numbers and the risk of any outcome was analysed using multivariable Cox regression models.Results Among the 807 patients,84(10.4%)patients had a recurrent ischaemic stroke within 1 year.After adjustment for conventional confounding factors,patients with both elevated hs-CRP levels and MAIs were associated with approximately 4.7-fold of risk of ischaemic stroke within 1 year(16.7% vs 3.5%,HR 4.68,95% CI 1.54 to 14.23,p=0.007),compared with those with non-elevated hs-CRP levels and NAI.Similar results were observed for the composite events.Conclusions Combined elevated hs-CRP levels and MAIs may increase 1-year stroke risk stratification efficiency in patients with minor ischaemic stroke or TIA compared with using those markers alone,which indicated that the combination of inflammatory and imaging markers might improve the effectiveness of risk stratification concerning minor ischaemic stroke or TIA. | Guangyao Wang Jing Jing Jiejie Li Yuesong Pan Hongyi Yan Xia Meng Xingquan Zhao Liping Liu Hao Li David Z Wang Yongjun Wang Yilong Wang | 2021 | Stroke & Vascular Neurology2021，6，1： | 11 |
| 15 | Endovascular treatment with or without intravenous alteplase for acute ischaemic stroke due to basilar artery occlusion显示文摘Background and purpose It remains controversial if endovascular treatment(EVT)can improve the outcome of patients with acute basilar artery occlusion(BAO).This study aims to compare the functional outcomes between EVT with and without intravenous thrombolysis(IVT)first in patients who had acute ischaemic stroke(AIS)due to BAO.Methods Patients who had AIS with BAO who underwent EVT within 24 hours of onset were enrolled in this multicentre cohort study,and the efficacy and safety were compared between IVT+EVT and direct EVT.The primary outcome was 90-day functional independence.All outcomes were assessed with adjusted OR(aOR)from the multivariable logistic regression.In addition,a meta-analysis was performed on all recently published pivotal studies on functional independence after EVT in patients with BAO.Results Of 310 enrolled patients with BAO,241(78%)were treated with direct EVT and 69(22%)with IVT+EVT.Direct EVT was associated with a worse functional outcome(aOR,0.46(95%CI 0.24 to 0.85),p=0.01).IVT+EVT was associated with a lower percentage of patients who needed≥3 passes of stent retriever(10.14%vs 20.75%).The meta-analysis regression revealed a potential positive correlation between bridging with IVT first and functional independence(r=0.14(95%CI 0.05 to 0.24),p<0.01).Conclusions This study showed that compared with direct EVT,EVT with IVT first was associated with better functional outcomes in patients with BAO treated within 24 hours of onset.The meta-analysis demonstrated similar favourable efficacy of IVT first followed by EVT in patients with BAO. | Ximing Nie David Wang Yuehua Pu Yufei Wei Qixuan Lu Hongyi Yan Xin Liu Lina Zheng Jingyi Liu Xinxuan Yang Yarong Ding Dacheng Liu Wanying Duan Zhe Zhang Zhonghua Yang Miao Wen Weibin Gu Xinyi Hou Xinyi Leng Yuesong Pan Zhongrong Miao Liping Liu | 2022 | Stroke & Vascular Neurology2022，7，3： | 10 |
| 16 | Observer-based adaptive consensus control for nonlinear multi-agent systems with time-delay显示文摘In this paper, we consider the observer-based adaptive consensus tracking problem for a class of nonlinear time-delay multi-agent systems in the presence of input saturation. Under the assumption that the communication topology is directed and connected, a distributed adaptive consensus controller is developed based on the dynamic surface control technique. By constructing the nonlinear observer, the unmeasurable agents dynamics can be estimated. Input saturation problem is solved by a smooth function combined with an auxiliary variable. With the help of prescribed performance functions, the synchronization errors converge to the prescribed sets, which are characterized as a neighborhood of zero. According to Lyapunov stability theory, it is shown that with the proposed distributed consensus tracking approach, the consensus errors are cooperatively semi-globally uniformly ultimately bounded. Finally, a simulation example is provided to show the effectiveness of the proposed algorithm. | Wenbin XIAO Liang CAO Hongyi LI Renquan LU | 2020 | Science China(Information Sciences)2020，63，3： | 10 |
| 17 | Longitudinal non-vascular transport pathways originating from acupuncture points in extremities visualised in human body显示文摘A subcutaneous transport pathway in humans has been previously visualised by injection of a paramagnetic tracer into the specific region of skin.In the current study,we further investigated the behaviours of imaging tracers in the transport pathways using imaging techniques.Three types of imaging tracers,including Gd-DTPA,iodised oil,and fluorescein sodium,were hypodermically injected into different acupuncture points of healthy volunteers to visualise the transport pathways by magnetic resonance imaging(MRI),X-ray,CT,and a digital fluorescein camera.Several longitudinal transport pathways in the arms and feet,which represent venous vessels and subcutaneous transport pathways(STPs) without well-defined boundaries,were visualised by MRI.Among the visualised veins,the partial walls of a few veins were enhanced by Gd-DTPA.The fluorescent images further indicated that STPs likely represent boundless pathways.The findings in this study suggested that specific anatomical structures within the subcutaneous tissues or the partial walls of certain veins werenot vascular conduits but rather represented unique transport pathways in humans that warrant extensive future studies. | Hongyi Li Jiabin Tong Weiguo Cao Min Chen Hua Li Hong Dai Liang Xu Xiaoliang Chen | 2014 | Chinese Science Bulletin2014，59，35： | 10 |
| 18 | Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield显示文摘Artemisia annua is the major natural source of artemisinin,an anti-malarial medicine commonly used worldwide.Here,we present chromosome-level haploid maps for two A.annua strains with different artemisinin contents to explore the relationships between genomic organization and artemisinin production.High-fidelity sequencing,optical mapping,and chromatin conformation capture sequencing were used to assemble the heterogeneous and repetitive genome and resolve the haplotypes of A.annua.Approximately 5o,ooo genes were annotated for each haplotype genome,and a triplication event that occurred approximately 58.12million years ago was examined for the first time in this species.A total of 3,903,467-5,193,414 variants(SNPs,indels,and structural variants)were identified in the 1.5-Gb genome during pairwise comparison between haplotypes,consistent with the high heterozygosity of this species.Genomic analyses revealed a correlation between artemisinin concents and the copy number of amorpha-4,11-dienes ynthasegenes.This correlation was further confirmed by resequencing of 36A.annua samples with varied artemisinin contents.Circular consensus sequencing of transcripts facilitated the detection of paralog expression.Collectively,our study provides chromosome-level allele-aware genome assemblies for two A.annua strains and new insights into the biosynthesis of artemisinin and its regulation,which will contribute to conquering malaria worldwide. | Baosheng Liao Xiaofeng Shen Li Xiang Shuai Guo Shiyu Chen Ying Meng Yu Liang Dandan Ding Junqi Bai Dong Zhang Tomasz Czechowski Yi Li Hui Yao Tingyu Mai Caroline Howard Chao Sun Haitao Liu Jiushi Liu Jin Pei Jihai Gao Jigang Wang Xiaohui Qiu Zhihai Huang Hongyi Li Ling Yuan Jianhe Wei lan Graham Jiang Xu Boli Zhang Shilin Chen | 2022 | Molecular Plant2022，15，8： | 9 |
| 19 | Changes of Precipitation and Extremes and the Possible Effect of Urbanization in the Beijing Metropolitan Region during 1960–2012 Based on Homogenized Observations显示文摘Daily precipitation series at 15 stations in the Beijing metropolitan region(BMR) during 1960–2012 were homogenized using the multiple analysis of series for homogenization method,with additional adjustments based on analysis of empirical cumulative density function(ECDF) regarding climate extremes.The cumulative density functions of daily precipitation series,the trends of annual and seasonal precipitation,and summer extreme events during 1960–2012 in the original and final adjusted series at Beijing station were comparatively analyzed to show the necessity and efficiency of the new method.Results indicate that the ECDF adjustments can improve the homogeneity of high-order moments of daily series and the estimation of climate trends in extremes.The linear trends of the regional-mean annual and seasonal(spring,summer,autumn,and winter)precipitation series are-10.16,4.97,-20.04,5.02,and-0.11 mm(10 yr)-1,respectively.The trends over the BMR increase consistently for spring/autumn and decrease for the whole year/summer; however,the trends for winter decrease in southern parts and increase in northern parts.Urbanization affects local trends of precipitation amount,frequency,and intensity and their geographical patterns.For the urban-influenced sites,urbanization tends to slow down the magnitude of decrease in the precipitation and extreme amount series by approximately-10.4% and-6.0%,respectively; enhance the magnitude of decrease in precipitation frequency series by approximately 5.7%; reduce that of extremes by approximately-8.9%; and promote the decreasing trends in the summer intensity series of both precipitation and extremes by approximately 6.8% and51.5%,respectively. | LI Zhen YAN Zhongwei TU Kai WU Hongyi | 2015 | Advances in Atmospheric Sciences2015，32，9： | 9 |
| 20 | Seismic performance of precast hollow bridge piers with different construction details显示文摘当前,预制的空具体的桥墩的设计计划将在中国在桥设计被采用,但是包括在高地震的风险区域的预制的部分墩的特定的设计细节没有代码。为有不同设计细节的空桥墩的地震性能的比较学习,空节桥码头的六个标本被设计并且测试。标本由整体的 cast-in-place 水泥桥墩组成,与联合的 cast-in-place 预制部分对的码头并且预制有干燥关节的部分具体的桥码头。结果证明所有标本有好排水量能力。有结合的对的海滨的桥墩展出更好的精力驱散能力和更高的力量。未结合的对的海滨桥墩显示更少的剩余塑料排水量和精力驱散能力。有在节的边的两个都结合的对的海滨的桥墩并且在节的中心未结合不仅展出更多的韧性能力和更少剩余塑料排水量,而且显示出更好的精力驱散能力。与对的桥列的试验性的结果相比,分析结果证明发达数字分析模型将提供合理、精确的结果。 | Zhiqiang WANG Jiping GE Hongyi WEI | 2014 | Frontiers of Structural and Civil Engineering2014，8，4： | 8 |
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