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| 1 | 42,573 cases of hepatectomy in China: a multicenter retrospective investigation显示文摘Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL^(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. | Binhao Zhang Bixiang Zhang Zhiwei Zhang Zhiyong Huang Yifa Chen Minshan Chen Ping Bie Baogang Peng Liqun Wu Zhiming Wang Bo Li Jia Fan Lunxiu Qin Ping Chen Jingfeng Liu Zhe Tang Jun Niu Xinmin Yin Deyu Li Songqing He Bin Jiang Yilei Mao Weiping Zhou Xiaoping Chen | 2018 | Science China(Life Sciences)2018,61,6: | 39 |
| 2 | Comparison of the clinical features and therapeutics of COVID-19 in cardio-cerebrovascular disease(CCVD)and non-CCVD patients显示文摘Cardio-cerebrovascular disease(CCVD)is a major comorbidity of coronavirus disease 2019(COVID-19).However,the clinical characteristics and outcomes remain unclear.In this study,102 cases of COVID-19 from January 22,2020 to March 26,2020 in Xixi Hospital of Hangzhou were included.Twenty cases had pre-existing CCVD.Results showed that compared with non-CCVD patients,those with CCVD are more likely to develop severe disease(15%versus 1%),and the proportion of pneumonia severity index grade IV was significantly higher(25%versus 3.6%).Computed tomography images demonstrated that the proportion of multiple lobe lesion involvement was significantly higher in the CCVD group than in the non-CCVD group(90%versus 63.4%).Compared with non-CCVD group,the levels of C-reactive protein,fibrinogen,D-dimer,and serum amyloid-A were higher,whereas the total protein and arterial partial Pa02 were lower in the CCVD group.Although no statistical difference was observed in the outcomes between groups,CCVD patients received more intensive comprehensive treatment to improve COVID-19 symptoms compared with non-CCVD patients.Integrated Chinese and Western medicine treatments have certain advantages in controlling the severe conversion rate and mortality of COVID-19.In addition,given that COVID-19 patients are usually related to coagulation disorders and thrombosis risk,the application of Chinese medicine in promoting blood circulation and removing stasis should be strengthened. | Yu Wang Lan Li Yuanjiang Pan Yu He Zuhua Chen Yunhao Xun Yuhan Xu Yilei Guo Jiehong Yang Jianchun Guo Haitong Wan | 2021 | Frontiers of Medicine2021,15,4: | 1 |
| 3 | Geomechanical and water vapor absorption characteristics of clay-bearing soft rocks at great depth显示文摘The geological and physico-mechanical properties characterization of deep soft rocks is one of the critical scientific issues for deep soft rock engineering. In the present study, X-ray diffraction(XRD) analysis,scanning electron microscope(SEM), and mercury intrusion porosimetry experiments were carried out to investigate the mineral compositions, microstructure and porosity characteristics of the 13 claybearing soft rock samples collected from a deep coal mine in China. Water vapor absorption and uniaxial compressive experiments were also performed to examine water absorption characteristics and waterinduced strength degradation effect of the investigated deep soft rock samples. The results show that the dominant mineral components in mudstone, coarse sandstone and fine sandstone samples were calcite, quartz and clay respectively. The contents of clay minerals in all samples were relatively high and ranged from 12.3%(N-4) to 56.5%(XS-1). Water vapor absorption processes of all the soft rock samples follow an exponential law which is very similar to the water vapor absorption behavior of conglomerate samples reported in our earlier study. Correlation analyses also suggested that there were good positive correlation relationships between water absorptivity and clay minerals for both mudstone and sandstone samples. Furthermore, it was found that vapor absorption was not correlated with the porosity for mudstone, however, positive correlation relationship was found between them for sandstone. Correlation analysis between UCS, modulus of elasticity and water content demonstrated that both of them tend to decrease with the increase of their water content due to water absorption. | Zhang Na Liu Longbiao Hou Dongwen He Manchao Liu Yilei | 2014 | International Journal of Mining Science and Technology2014,24,6: | 1 |
| 4 | Anchoring nitrogen-doped Co_(2)P nanoflakes on NiCo_(2)O_(4)nanorod arrays over nickel foam as high-performance 3D electrode for alkaline hydrogen evolution显示文摘Effective and robust electrocatalysts are mainly based on innovative materials and unique structures.Herein,we designed a flakelike cobalt phosphide-based catalyst supporting on NiCo_(2)O_(4)nanorods array,which in-situ grew on the nickel foam(NF)current collector,referring as NCo_(2)P/NiCo_(2)O_(4)/NF electrode.By optimizing the microstructure and electronic structure through 3D hierarchy fabrication and nitrogen doping,the catalyst features with abundant electrochemical surface area,favorable surface wettability,excellent electron transport,as well as tailored d band center.Consequently,the as-prepared N-Co_(2)P/NiCo_(2)O_(4)/NF electrode exhibits an impressive HER activity with a low overpotentials of58 mV at 10 mA cm^(-2),a Tafel slop of 75 mV dec^(-1),as well as superior durability in alkaline medium.This work may provide a new pathway to effectively improve the hydrogen evolution performance of transition metal phosphides and to develop promising electrodes for practical electrocatalysis. | Xiaohao Ji Xiaoyu Chen Lijuan Zhang Cheng Meng Yilei He Xing Zhang Zumin Wang Ranbo Yu | 2023 | Green Energy & Environment2023,8,2: | 1 |
| 5 | Optimization of Chinese solar greenhouse building parameters based on CFD simulation and entropy weight method显示文摘The building parameters of Chinese solar greenhouse(CSG)directly affect the front roof lighting and indoor thermal environment.In order to obtain the optimal parameter combination,a building parameter optimization method based on computational fluid dynamics(CFD)simulation and entropy weight method was proposed.Firstly,a three-dimensional thermal and humidity environment model of CSG was constructed considering the coupling effect of soil,crop,and back wall based on CFD.The reliability of the model was validated through experiments in a CSG of Yongqing County,Hebei Province of China.Then,the indoor air temperature rise rate,air temperature and humidity uneven coefficient,and average air temperature and humidity were selected as the evaluation indicators of CSG thermal and humidity environment.The ridge height,back wall height and the horizontal projection of back roof of CSG were selected as the three factors of the orthogonal test plan,and a three-factor and four-level plan was designed,resulting in 16 different parameter combinations.By use of CFD simulation,the thermal and humidity environment evaluation indicators under different parameter combinations were calculated.The entropy weight method was used to assign weights to the evaluation indicators,and the comprehensive evaluation indicators of CSG thermal and humidity environment were obtained based on the linear weighting principle.By comparing comprehensive evaluation indicators,the optimal combination of building parameters was obtained with a ridge height of 5.72 m,a back wall height of 3.2 m,and a horizontal projection of 2.1 m on the back roof.The research results can provide a practical and feasible method for optimizing the building parameters of CSG,and provided theoretical guidance for the structural design and optimization of CSG. | Fen He Changqing Si Xiaoming Ding Zhenjun Gao Binbin Gong Fei Qi Yilei Yin Qian Feng | 2023 | International Journal of Agricultural and Biological Engineering2023,16,6: | 0 |
| 6 | OsHG3 Affects Rice Palea Development, Grain Yield and Quality显示文摘Floral development is one of the most important determining factors of grain yield in cereal crops(Immink et al,2010).The rice inflorescence is composed of the spikelet,a specific structural unit in poaceae,which is greatly different from typical eudicots.However,several genes encoding the homologous of the proteins in ABCDE model were also found in rice genome(Luo and Zhu,2002).Lemma and palea are grass-specific floret tissues which interlock with each other to protect the inner floral organs and seeds from attack by pathogens,insects or abiotic stresses.Meanwhile,they have photosynthetic ability and provide amino acids and carbohydrates to grouting seeds. | Ouyang Linjuan Xu Minyu Hu Jiang Zhu Lixin Li Ting Xu Yilei Zhu Changlan Peng Xiaosong Chen Xiaorong He Haohua Xu Jie | 2020 | Rice science2020,27,5: | 0 |
| 7 | 单细胞技术揭示肝癌免疫图谱与动态特征显示文摘文章简介肝细胞癌是世界范围内死亡率排名第三的癌症,其中中国的肝癌发病率居世界之先。肿瘤存在多种免疫逃逸机制,提出了研究肿瘤微环境中不同免疫细胞状态的重要性。而不同类型的单细胞测序技术则是研究不同类型免疫细胞的状态和动态的有力手段。本研究结合了两种单细胞测序技术,充分发挥不同数据类型的优势,获得高分辨率的肝癌免疫图谱。肿瘤中的树突状细胞是重要的抗原呈递细胞,除传统的树突状细胞外。 | Qiming Zhang Yao He Nan Luo Shashank J.Patel Yanjie Han Ranran Gao Madhura Modak Sebastian Carotta Christian Haslinger David Kind Gregory W.Peet Guojie Zhong Shuangjia Lu Weihua Zhu Yilei Mao Mengmeng Xiao Michael Bergmann Xueda Hu Sid P.Kerkar Anne B.Vogt Stefan Pflanz Kang Liu 彭吉润 任仙文 张泽民 | 2020 | 科学新闻2020,,2: | 0 |
| 8 | Ti-MOF Derived N-Doped TiO2 Nanostructure as Visible-light-driven Photocatalyst显示文摘Nanostructured N-doped TiO2 photocatalyst has been prepared via a new approach from Ti-based MOF[NH2-MIL-125(Ti)]precursor.The success of N doping enhances light absorption and narrows the bandgap.Moreover,the as-prepared nanostructure is constructed with tiny nanoparticles and resembles a pie-like morphology inherited from the MOF,which accelerates electron transfer.Hence,as a photocatalyst for the degradation of methylene blue(MB)under visible light irradiation,the N-doped TiO2(N-TiO2)nanostructure shows higher photocatalytic activity with a reaction rate constant of 0.018min^-1 than that of the TiO2-P25 and TiO2 under the visible light. | HE Yilei ZHANG Xing WEI Yanze CHEN Xiaoyu WANG Zumin YU Ranbo | 2020 | Chemical Research in Chinese Universities2020,36,3: | 0 |