|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 0.04 degree-per-hour MEMS disk resonator gyroscope with high-quality factor (510 k) and long decaying time constant(74.9 s)显示文摘The disk resonator gyroscope is an attractive candidate for high-performance MEMS gyroscopes.This gyroscope consists of a sensor and readout electronics,and the characteristics of the sensor directly determine the performance.For the sensor,a high-quality factor and long decaying time constant are the most important characteristics required to achieve high performance.We report a disk resonator gyroscope with a measured quality factor of 510 k and decaying time constant of 74.9 s,which is a record for MEMS silicon disk resonator gyroscopes,to the best of our knowledge.To improve the quality factor of the DRG,the quality factor improvement mechanism is first analyzed,and based on this mechanism two stiffness-mass decoupled methods,i.e.,spoke length distribution optimization and lumped mass configuration design,are proposed and demonstrated.A disk resonator gyroscope prototype is fabricated based on these design strategies,and the sensor itself shows an angle random walk as low as 0.001°/√h,demonstrating true potential to achieve navigation-grade performance.The gyroscope with readout electronics shows an angle random walk of 0.01°/√h and a bias instability of 0.04°/h at room temperature without compensation,revealing that the performance of the gyroscope is severely limited by the readout electronics,which should be further improved.We expect that the quality factor improvement methods can be used in the design of other MEMS gyroscopes and that the newly designed DRG can be further improved to achieve navigation-grade performances for high-end industrial,transportation,aerospace,and automotive applications. | Qingsong Li Dingbang Xiao Xin Zhou Yi Xu Ming Zhuo Zhanqiang Hou Kaixuan He Yongmeng Zhang Xuezhong Wu | 2018 | Microsystems & Nanoengineering2018，4，1： | 16 |
| 2 | Hierarchical method of task assignment for multiple cooperating UAV teams显示文摘The problem of task assignment for multiple cooperating unmanned aerial vehicle(UAV) teams is considered. Multiple UAVs forming several small teams are needed to perform attack tasks on a set of predetermined ground targets. A hierarchical task assignment method is presented to address the problem. It breaks the original problem down to three levels of sub-problems: target clustering, cluster allocation and target assignment. The first two sub-problems are centrally solved by using clustering algorithms and integer linear programming, respectively, and the third sub-problem is solved in a distributed and parallel manner, using a mixed integer linear programming model and an improved ant colony algorithm. The proposed hierarchical method can reduce the computational complexity of the task assignment problem considerably, especially when the number of tasks or the number of UAVs is large. Experimental results show that this method is feasible and more efficient than non-hierarchical methods. | Xiaoxuan Hu Huawei Ma Qingsong Ye He Luo | 2015 | Journal of Systems Science & Complexity2015，28，5： | 14 |
| 3 | Application of bioactive hydrogels combined with dental pulp stem cells for the repair of large gap peripheral nerve injuries显示文摘Due to the limitations in autogenous nerve grafting or Schwann cell transplantation,large gap peripheral nerve injuries require a bridging strategy supported by nerve conduit.Cell based therapies provide a novel treatment for peripheral nerve injuries.In this study,we first experimented an optimal scaffold material synthesis protocol,from where we selected the 10%GFD formula(10%GelMA hydrogel,recombinant human basic fibroblast growth factor and dental pulp stem cells(DPSCs))to fill a cellulose/soy protein isolate composite membrane(CSM)tube to construct a third generation of nerve regeneration conduit,CSM-GFD.Then this CSM-GFD conduit was applied to repair a 15-mm long defect of sciatic nerve in a rat model.After 12 week post implant surgery,at histologic level,we found CSM-GFD conduit could regenerate nerve tissue like neuron and Schwann like nerve cells and myelinated nerve fibers.At physical level,CSM-GFD achieved functional recovery assessed by a sciatic functional index study.In both levels,CSM-GFD performed like what gold standard,the nerve autograft,could do.Further,we unveiled that almost all newly formed nerve tissue at defect site was originated from the direct differentiation of exogeneous DPSCs in CSM-GFD.In conclusion,we claimed that this third-generation nerve regeneration conduit,CSM-GFD,could be a promising tissue engineering approach to replace the conventional nerve autograft to treat the large gap defect in peripheral nerve injuries. | Lihua Luo Yan He Ling Jin Yanni Zhang Fernando P.Guastaldi Abdullkhaleg A.Albashari Fengting Hu Xiaoyan Wang Lei Wang Jian Xiao Lingli Li Jianming Wang Akon Higuchi Qingsong Ye | 2021 | Bioactive Materials2021，6，3： | 11 |
| 4 | Hybrids perfluorosulfonic acid ionomer and silicon oxide membrane for application in ion-exchange polymer-metal composite actuators显示文摘This paper reports a new technique to fabricate an ion-exchange polymer-metal composite (IPMC) actuator. This technique is based on a hybrid organic-inorganic composite membrane. In the fabrication course, silica oxide particles, prepared from hydrolysis of tetraethyl orthosilicate in situ with sol-gel reaction, co-crystallize with perfluorosulfonate acid (PFSA) ionomer. Attenuated total reflectance fourier transform infrared spectroscopy (ATR-FTIR) analyses demonstrate that a highly water-saving hybrid membrane is formed. Measurements of mechanical properties reveal that elastic modulus and hardness of the hybrid membrane are about 2 times compared to a commercial PFSA membrane. Scanning electron microscopy (SEM) results show that the hybrid membrane has a high porosity. Inside the membrane pores, there exists a great quantity of micro scale channels in the range of 100―300 nm. After fabrication of IPMC actuator, an electric current sensor, a force sensor, and a high speed camera are assembled and used to evaluate IPMC performance. It is shown that, compared to an IPMC actuator made from a commercial membrane, the electromechanical performance of the new actuator increases 6―8 times; when it is actuated in air, its stable non-water working time is prolonged for 6―7 times. | GUO DongJie DING HaiTao WEI HaiJu HE QingSong YU Min DAI ZhenDong | 2009 | Science China(Technological Sciences)2009，52，10： | 10 |
| 5 | Luobusaite:A New Mineral显示文摘A group of mantle minerals including about 70-80 subtypes of minerals are discovered from a podiform chromitite in Tibet,China.Recovered minerals include diamond,coesite,moissanite,wustite,Fe-silides and a new mineral,luobusaite.All of these minerals were hand-picked from heavy-mineral separates of the podiform chromitite in the mantle peridotite of an ophiolite.The grains of luobusaite are as host mineral with inclusions of native silicon or as an intergrowth with native silicon and Fe-Si phase.Luobusaite occurs as irregular grains,with 0.1-0.2 mm in size,consisting of very fine-grained aggregates.The mineral is steel-grey in color,metallic luster,and opaque.The empirical formula(based on 2 for Si)is Fe0.83Si2,according to the chemical compositions of luobusaite.X-ray powder-diffraction data:orthorhombic system,space group Cmca,a = 9.874(14)?,b = 7.784(5)?,c= 7.829(7)?,Z=16. | BAI Wenji SHI Nicheng FANG Qingsong LI Guowu XIONG Ming YANG Jingsui RONG He | 2006 | Acta Geologica Sinica(English Edition)2006，80，5： | 10 |
| 6 | Experimental Study and Model Analysis of the Performance of IPMC Membranes with Various Thickness显示文摘 | Qingsong He Min Yu Linlin Song Haitao Ding Xiaoqing Zhang Zhendong Dai | 2011 | Journal of Bionic Engineering2011，8，1： | 10 |
| 7 | Titanium, Ti, A New Mineral Species from Luobusha, Tibet, China显示文摘We describe the new mineral species titanium,ideally Ti,found in the podiform chromitites of the Luobusha ophiolite in Tibet,People's Republic of China.The irregular crystals range from 0.1 to 0.6 mm in diameter and form an intergrowth with coesite and kyanite.Titanium is silver grey in colour,the luster is metallic,it is opaque,the streak is grayish black,and it is non-fluorescent.The mineral is malleable,has a rough to hackly fracture and has no apparent cleavage.The estimated Mohs hardness is 4,and the calculated density is 4.503 g/cm3.The composition is Ti 99.23-100.00 wt%.The mineral is hexagonal,space group P63 /mmc.Unit-cell parameters are a 2.950(2),c 4.686(1),V 35.32(5) 3,Z = 2.The five strongest powder diffraction lines [d in(hkl)(I/I0)] are: 2.569(010)(32),2.254(011)(100),1.730(012)(16),1.478(110)(21),and 0.9464(121)(8).The species and name were approved by the CNMNC(IMA 2010–044). | FANG Qingsong BAI Wenji YANG Jingsu RONG He SHI Nicheng LI Guowu XIONG Ming MA Zhesheng | 2013 | Acta Geologica Sinica(English Edition)2013，87，5： | 7 |
| 8 | Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improves long circulation and enhances cellular uptake in cancer therapy显示文摘Hyaluronic acid(HA) is a natural ligand of tumor-targeted drug delivery systems(DDS) due to the relevant CD44 receptor overexpressed on tumor cell membranes. However, other HA receptors(HARE and LYVE-1) are also overexpressing in the reticuloendothelial system(RES). Therefore,polyethylene glycol(PEG) modification of HA-based DDS is necessary to reduce RES capture.Unfortunately, pegylation remarkably inhibits tumor cellular uptake and endosomal escapement,significantly compromising the in vivo antitumor efficacy. Herein, we developed a Dox-loaded HA-based transformable supramolecular nanoplatform(Dox/HCVBP) to overcome this dilemma. Dox/HCVBP contains a tumor extracellular acidity-sensitive detachable PEG shell achieved by a benzoic imine linkage.The in vitro and in vivo investigations further demonstrated that Dox/HCVBP could be in a 'stealth' state at blood stream for a long circulation time due to the buried HA ligands and the minimized nonspecific interaction by PEG shell. However, it could transform into a 'recognition' state under the tumor acidic microenvironment for efficient tumor cellular uptake due to the direct exposure of active targeting ligand HA following PEG shell detachment. Such a transformative concept provides a promising strategy to resolve the dilemma of natural ligand-based DDS with conflicting two processes of tumor cellular uptake and in vivo nonspecific biodistribution. | Lu Zhong Lu Xu Yanying Liu Qingsong Li Dongyang Zhao Zhenbao Li Huicong Zhang Haotian Zhang Qiming Kan Yongjun Wang Jin Sun Zhonggui He | 2019 | Acta Pharmaceutica Sinica B2019，9，2： | 7 |
| 9 | Adhesion Characteristics of a Novel Synthetic Polydimethylsiloxane for Bionic Adhesive Pads显示文摘 | Qingsong He Min Yu Yang Li Xinlong Chen Hao Zhang Ling Gong Zhendong Dai | 2014 | Journal of Bionic Engineering2014，11，3： | 6 |
| 10 | Advanced Electro-active Dry Adhesive Actuated by an Artificial Muscle Constructed from an Ionic Polymer Metal Composite Reinforced with Nitrogen-doped Carbon Nanocages显示文摘 | Qingsong He Xu Yang Zhongyuan Wang Jin Zhao Min Yu Zhen Hu Zhendong Dai | 2017 | Journal of Bionic Engineering2017，14，3： | 5 |
| 11 | Mesoporous silica rods with cone shaped pores modulate inflammation and deliver BMP-2 for bone regeneration显示文摘Biomaterials with suitable osteoimmunomodulation properties and ability to deliver osteoinductive biomolecules,such as bone morphogenetic proteins,are desired for bone regeneration.Herein,we report the development of mesoporous silica rods with large cone-shaped pores(MSR-CP)to load and deliver large protein drugs.It is noted that those cone-shaped pores on the surface modulated the immune response and reduced the pro-inflammatory reaction of stimulated macrophage.Furthermore,bone morphogenetic proteins 2(BMP-2)loaded MSR-CP facilitated osteogenic differentiation and promoted osteogenesis of bone marrow stromal cells.In vivo tests confirmed BMP-2 loaded MSR-CP improved the bone regeneration performance.This study provides a potential strategy for the design of drug delivery systems for bone regeneration. | Chun Xu Lan Xiao Yuxue Cao Yan He Chang Lei Yin Xiao Wujin Sun Samad Ahadian Xueting Zhou Ali Khademhosseini Qingsong Ye | 2020 | Nano Research2020，13，9： | 5 |
| 12 | A New Method Based on Association Rules Mining and Geo-filter for Mining Spatial Association Knowledge显示文摘Association rule mining methods, as a set of important data mining tools, could be used for mining spatial association rules of spatial data. However, applications of these methods are limited for mining results containing large number of redundant rules. In this paper, a new method named Geo-Filtered Association Rules Mining(GFARM) is proposed to effectively eliminate the redundant rules. An application of GFARM is performed as a case study in which association rules are discovered between building land distribution and potential driving factors in Wuhan, China from 1995 to 2015. Ten sets of regular sampling grids with different sizes are used for detecting the influence of multi-scales on GFARM. Results show that the proposed method can filter 50%–70% of redundant rules. GFARM is also successful in discovering spatial association pattern between building land distribution and driving factors. | LIU Yaolin XIE Peng HE Qingsong ZHAO Xiang WEI Xiaojian TAN Ronghui | 2017 | Chinese Geographical Science2017，27，3： | 5 |
| 13 | Investigation of Ionic Polymer Metal Composite Actuators Loaded with Various Tetraethyl Orthosilicate Contents显示文摘 | Qingsong He Min Yu Yuxiu Li Yan Ding Dongjie Guo Zhendong Dai | 2012 | Journal of Bionic Engineering2012，9，1： | 3 |
| 14 | Beclin-1/LC3-II dependent macroautophagy was uninfluenced in ischemia-challenged vascular endothelial cells显示文摘Autophagy has been extensively studied and occurs in many biological settings.However,a question remains as to whether ischemia enhances Beclin-1/LC3-II-dependent macroautophagy in vascular endothelial cells,as has been previously thought.Furthermore,the effect of the level of autophagy on cell or skin flap survival still requires elucidation.We created a lethal ischemia model in human umbilical vascular endothelial cells(HUVECs),performed quantitative proteomics and bioinformatics analyses,and verified the autophagic status and effect both in vitro and in vivo.The significantly upregulated proteins encoded by autophagy-related genes(ATGs)included ATG2A,ATG3,ATG4B,ATG5,ATG7,ATG9A,ATG12,ATG16,and ATG101.The significantly enhanced lysosomal proteins were cathepsin B,cathepsin D,lysosome-associated membrane protein 1(LAMP1),and LAMP2.However,the differentially expressed proteins excluded Beclin-1,microtubule-associated protein light chain 3(LC3)-I,and LC3-II.Western blot analyses verified that the protein expression levels of Beclin-1,LC3-I,and LC3-II were neither upregulated nor downregulated in ischemia-challenged HUVECs.The autophagic status was not enhanced by rapamycin in ischemic HUVECs but appeared to be inhibited by chloroquine.Our in vivo study on rats showed that a downregulation in autophagic status jeopardized skin flap survival.In conclusion,Ischemia neither enhanced nor inhibited Beclin-1/LC3-II-dependent canonical macroautophagy both in vitro and in vivo,in contradiction to previous studies.An appropriate autophagic homeostasis can minimize cell or skin flap damage. | Yaping Ma Chaofan Li Yan He Tiwei Fu Li Song Qingsong Ye Fugui Zhang | 2022 | Genes & Diseases2022，9，2： | 3 |
| 15 | Force optimization of ionic polymer metal composite actuators by an orthogonal array method显示文摘Ionic polymer metal composites (IPMCs), a new kind of electro-active polymer, can be used for micro robotic actuators, artificial muscles and dynamic sensors. However, IPMC actuators have the major drawbacks of a low generative blocking force and dependence on a humid environment, which limit their further application. Multiple process parameters for the fabrication of IPMCs were optimized to produce a maximum blocking force; the parameters included reducing agent concentration, platinum salt concentration in the initial compositing process, and tetraethyl orthosilicate (TEOS) content. An orthogonal array method was designed and a series of fabrication experiments were carried out to identify the optimum process parameters. The results show that the platinum salt concentration in the initial compositing process plays the most significant role in improving the blocking force of IPMCs, the TEOS content plays an important role, and the reducing agent concentration has no apparent effect on the blocking force. In the optimized conditions, the IPMC actuator exhibited maximum blocking force of 50 mN, and the corresponding displacement was 14 mm. Compared with normal conditions, the blocking force improved 2.4-fold without sacrificing the displacement, and the effective air-operating life was prolonged 5.8-fold for the blocking force and 5-fold for the displacement. This study lays a solid foundation for further applications of IPMCs. | YU Min HE QingSong DING Yan GUO DongJie LI JiaBo DAI ZhenDong | 2011 | Chinese Science Bulletin2011，56，19： | 3 |
| 16 | Motion Control of Capsule-like Underwater Robot Utilizing the Swing Properties of Ionic Polymer Metal Composite Actuators显示文摘Ionic Polymer Metal Composite(IPMC)is a novel electrically actuated intelligent material with the advantages of big bending displacement,low driving voltage,flexible and so on.It has been recognized as one of the most attractive actuators with prospective applications for underwater robots and bionic organs.In this work,a capsule-like robot was introduced with the pectoral and caudal fins made of IPMC.By analyzing the properties of displacement response to square waves with different frequencies and low level voltages,it was found that performance of IPMC are frequency sensitive.Besides,when the absolute value of low level voltage decreases,IPMC could swing on one side with the decrease in amplitudes,whereas the amplitude at high level voltage fluctuates within small ranges at low frequencies.IPMC tip can approximately maintain when the frequency of driving signal around 30 Hz.Such properties were employed to control the locomotion of robot combining the motions of pectoral and caudal fin.Thus,the locomotions of swimming forward,turning and positioning were realized. | Hongkai Li Min Fan Yinghao Yue Guoliang Hu Qingsong He Min Yu | 2020 | Journal of Bionic Engineering2020，17，2： | 3 |
| 17 | Hypoxia response element-directed expression of bFGF in dental pulp stem cells improve the hypoxic environment by targeting pericytes in SCI rats显示文摘Cell-based transplantation strategies possess great potential for spinal cord injury(SCI)repair.Basic fibroblast growth factor(bFGF)has been reported to have multiple neuro-promoting effects on developing and adult nervous system of mammals and considered a promising therapy for nerve injury following SCI.Human dental pulp stem cells(DPSCs)are abundant stem cells with low immune rejection,which can be considered for cell replacement therapy.The purpose of this study was to investigate the roles of DPSCs which express bFGF under the regulation of five hypoxia-responsive elements(5HRE)using an adeno-associated virus(AAV-5HRE-bFGF-DPSCs)in SCI repairing model.In this study,DPSCs were revealed to differentiate into CD13^(+)pericytes and up-regulate N-cadherin expression to promote the re-attachment of CD13^(+)pericytes to vascular endothelial cells.The re-attachment of CD13^(+)pericytes to vascular endothelial cells subsequently increased the flow rate of blood in microvessels via the contraction of protuberance.As a result,increased numbers of red blood cells carried more oxygen to the damaged area and the local hypoxia microenvironment in SCI was improved.Thus,this study represents a step forward towards the potential use of AAV-5HRE-bFGF-DPSCs in SCI treatment in clinic. | Sipin Zhu Yibo Ying Yan He Xingxing Zhong Jiahui Ye Zhiyang Huang Min Chen Qiuji Wu Yifan Zhang Ziyue Xiang Yurong Tu Weiyang Ying Jian Xiao Xiaokun Li Qingsong Ye Zhouguang Wang | 2021 | Bioactive Materials2021，6，8： | 2 |
| 18 | Yarlongite:A New Metallic Carbide Mineral显示文摘Yarlongite 在 Luobusha 矿发生在 ophiolitic chromitite (29 ° 5 “ N 92 ° 5 ” E,拉萨的大约 200 km ESE ) , Qusum 县, Shannan 府,西藏自治区域,中华人民共和国。联系矿物质是:钻石, moissanite, w ü s tite,铱(“ osmiridium ”) ,锇(“铱锇矿”) ,方镁石,铬铁矿,本国的铁,本国的镍,本国的铬, forsterite, Cr 富有的透辉石,金属间化合的混合物 Ni-Fe-Cr, Ni-Cr, Cr-C,等等。Yarlongite 和它的联系矿物质从 chromitite 的一件大重矿物质样品是精选的。与 yarlongite 联系的金属性的碳化物是 cohenite, tongbaite, khamrabaevite 和 qusongite (IMA2007 034 ) 。Yarlongite 作为不规则的谷物发生,与在 0.02 和 0.06 公里之间的一种尺寸,钢灰色颜色, H Mohs:5 ½
6。固执:易碎。劈开:{ 0 0 1 } 完美。骨折:贝壳状。化学公式:(Cr 4 Fe 4 Ni )Σ9 C 4, 或(Cr, Fe, Ni )Σ9 C 4, 水晶系统:六角形,空间组:P6 3/mc,a= 18.839 (2 )Å
, c= 4.4960 (9 )Å
, V= 745.7 (2 )Å
3, Z= 6,密度(计算)= 7.19 g/cm 3( 与简化公式) 。Yarlongite 被 CNMNC (IMA2007 035 ) 作为一种新矿物质同意了。完模标本材料在中国的地质的博物馆被扔(没有。M11650 ) 。 | SHI Nicheng BAI Wenji LI Guowu XIONG Ming FANG Qingsong YANG Jingsui MA Zhesheng RONG He | 2009 | Acta Geologica Sinica(English Edition)2009，83，1： | 2 |
| 19 | Optimized Bio-inspired Micro-pillar Dry Adhesive and Its Application for an Unmanned Aerial Vehicle Adhering on and Detaching from a Ceiling显示文摘Various bio-inspired dry adhesive materials have been investigated.In this work,lithography and silicon deep etching method were used to fabricate bio-inspired micro-pillar dry adhesive materials of which the parameters,such as side length,Height to Side length Aspect Ratio(HSAR),and inter-pillar Distance to Side length Aspect Ratio(DSAR)were comprehensively studied to obtain a dry adhesive with high adhesion.An orthogonal array method was designed and a series of fabrication experiments were conducted to identify optimum parameters,which resulted in a high normal adhesion of 2.98 N·cm^-2 and a shear adhesion of 9.59 N·cm^-2.An adhesion and desorption device was further designed on basis of the optimum dry adhesive,which enables an Unmanned Aerial Vehicle(UAV)to successfully adhere on and detach from a ceiling.This would allow an UAV to stay aloft for prolonged time,which could be invaluable to many applications,such as energy conservation and aerial detection. | Qingsong He Xianrui Xu Zhiwei Yu Kai Huo Zhaoyang Wang Nuo Chen Xuean Sun Gui Yin Peile Du Yang Li Zhendong Dai | 2020 | Journal of Bionic Engineering2020，17，1： | 2 |
| 20 | Significantly Enhanced Actuation Performance of IPMC by Surfactant-Assisted Processable MWCNT/Nafion Composite显示文摘 | Qingsong He Min Yu Dingshan Yu Yan Ding Zhendong Dai | 2013 | Journal of Bionic Engineering2013，10，3： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员