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| 1 | Dissimilatory Fe(Ⅲ) reduction characteristics of paddy soil extract cultures treated with glucose or fatty acids显示文摘Dissimilatory Fe(Ⅲ) reduction is a universal process with irreplaceable biological and environmental importance in anoxic environments. Our knowledge about Fe(Ⅲ) reduction predominantly comes from pure cultures of dissimilatory Fe(Ⅲ) reducing bacteria (DFRB). The objective of this study was to compare the effects of glucose and a selection of short organic acids (citrate, succinate, pyruvate, propionate, acetate, and formate) on Fe(Ⅲ) reduction via the anaerobic culture of three paddy soil solutions with Fe(OH)3 as the sole electron acceptor. The results showed significant differences in Fe(Ⅲ) reduction among the three paddy soil solutions and substrate types. Bacteria from the Sichuan paddy soil responded quickly to substrate supply and showed higher Fe(Ⅲ) reducing activity than the other two soil types. Bacteria in the Jiangxi paddy soil culture solution could not use propionate as a source of electrons for Fe(Ⅲ) reduction. Similarly, bacteria in the Jilin paddy soil culture could not use succinate effectively. Pyruvate was readily used by cultures from all three paddy soil solutions, thus indicating that there were some similarities in substrate utilization by bacteria for Fe(Ⅲ) reduction. The use of glucose and citrate as substrate for dissimilatory Fe(Ⅲ) reduction indicates important ecological implications for this type of anoxic respiration. | HE Jiangzhou1,2, QU Dong1, 1. College of Resources and Environment, Northwest A & F University, Yangling, Shaanxi 712100, China.2. Xinjiang Production & Construction Corps Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin, Tarim University, Alar, Xinjiang Uygur Autonomous Region, Xinjiang 843300, China | 2008 | Journal of Environmental Sciences2008，20，9： | 24 |
| 2 | Optimizing Parameters of CSM-CERES-Maize Model to Improve Simulation Performance of Maize Growth and Nitrogen Uptake in Northeast China显示文摘Crop models can be useful tools for optimizing fertilizer management for a targeted crop yield while minimizing nutrient losses.In this paper,the parameters of the decision support system for agrotechnology transfer(DSSAT)-CERES-Maize were optimized using a new method to provide a better simulation of maize(Zea mays L.) growth and N uptake in response to different nitrogen application rates.Field data were collected from a 5 yr field experiment(2006-2010) on a Black soil(Typic hapludoll) in Gongzhuling,Jilin Province,Northeast China.After cultivar calibration,the CERES-Maize model was able to simulate aboveground biomass and crop yield of in the evaluation data set(n-RMSE=5.0-14.6%),but the model still over-estimated aboveground N uptake(i.e.,with E values from-4.4 to-21.3 kg N ha-1).By analyzing DSSAT equation,N stress coefficient for changes in concentration with growth stage(CTCNP2) is related to N uptake.Further sensitivity analysis of the CTCNP2 showed that the DSSAT model simulated maize nitrogen uptake more precisely after the CTCNP2 coefficient was adjusted to the field site condition.The results indicated that in addition to calibrating 6 coefficients of maize cultivars,radiation use efficiency(RUE),growing degree days for emergence(GDDE),N stress coefficient,CTCNP2,and soil fertility factor(SLPF) also need to be calibrated in order to simulate aboveground biomass,yield and N uptake correctly.Independent validation was conducted using 2008-2010 experiments and the good agreement between the simulated and the measured results indicates that the DSSAT CERES-Maize model could be a useful tool for predicting maize production in Northeast China. | LIU Hai-long YANG Jing-yi HE Ping BAI You-lu JIN Ji-yun Craig F Drury ZHU Ye-ping YANGXue-ming LI Wen-juan XIE Jia-gui YANG Jing-min Gerrit Hoogenboom | 2012 | Journal of Integrative Agriculture2012，11，11： | 13 |
| 3 | Visualizing the microtubule-associated protein tau in the nucleus显示文摘Although tau is mainly known as an axonal microtubule-associated protein,many studies indicate that it is not restricted to this subcellular compartment.Assessing tau’s subcellular distribution,however,is not trivial as is evident from transgenic mouse studies.When human tau is over-expressed,it can be immunohistochemically localized to axons and the somatodendritic domain,modeling what is found in neurodegenerative diseases such as Alzheimer’s disease.Yet,in wild-type mice,despite its abundance,tau is difficult to visualize even in the axon.It is even more challenging to detect this protein in the nucleus,where tau has been proposed to protect DNA from damage.To establish a framework for future studies into tau’s nuclear functions,we compared several methods to visualize endogenous nuclear tau in cell lines and mouse brain.While depending on the fixation and permeabilization protocol,we were able to detect nuclear tau in SH-SY5Y human neuroblastoma cells,we failed to do so in N2a murine neuroblastoma cells.As a second method we used subcellular fractionation of mouse tissue and found that in the nucleus tau is mainly present in a hypophosphorylated form.When either full-length or truncated human tau was expressed,both accumulated in the cytoplasm,but were also found in the nuclear fraction.Because subcellular fractionation methods have their limitations,we finally isolated nuclei to probe for nuclear tau and found that the nuclei were free of cytoplasmic contamination.Together our analysis identifies several protocols for detecting tau in the nucleus where it is found in a less phosphorylated form. | LU Jing LI Ting HE RongQiao BARTLETT Perry F GTZ Jürgen | 2014 | Science China(Life Sciences)2014，57，4： | 11 |
| 4 | Transcriptome profile of human neuroblastoma cells in the hypomagnetic field显示文摘Research has shown that the hypomagnetic field(HMF)can affect embryo development,cell proliferation,learning and memory,and in vitro tubulin assembly.In the present study,we aimed to elucidate the molecular mechanism by which the HMF exerts its effect,by comparing the transcriptome profiles of human neuroblastoma cells exposed to either the HMF or the geomagnetic field.A total of 2464 differentially expressed genes(DEGs)were identified,216 of which were up-regulated and2248 of which were down-regulated after exposure to the HMF.These DEGs were found to be significantly clustered into several key processes,namely macromolecule localization,protein transport,RNA processing,and brain function.Seventeen DEGs were verified by real-time quantitative PCR,and the expression levels of nine of these DEGs were measured every 6 h.Most notably,MAPK1 and CRY2,showed significant up-and down-regulation,respectively,during the first 6 h of HMF exposure,which suggests involvement of the MAPK pathway and cryptochrome in the early bio-HMF response.Our results provide insights into the molecular mechanisms underlying the observed biological effects of the HMF. | MO WeiChuan LIU Ying BARTLETT Perry F HE RongQiao | 2014 | Science China(Life Sciences)2014，57，4： | 8 |
| 5 | 16年随访的前瞻性队列中521120名个体的膳食脂肪摄入与总死亡率和特定原因死亡率的关系显示文摘饱和脂肪摄入与心血管健康相关性的证据存在争议。不饱和脂肪和总死亡率及心血管病死亡率的相关性存在不一致性,并且关于非心血管病死亡率的数据较少。该文旨在评估膳食脂肪与总死亡率和特定原因死亡率的关系。方法和结果:研究者分析了来自随访16年的美国国立卫生研究院一美国退休人员协会膳食与健康研究年龄50~71岁的参与者521 120人的数据。通过食品频率问卷评估饱和脂肪酸(saturatedfatty acid,SFA )、反式脂肪酸(trans-fatty acid,TFA)、单不饱和脂肪酸(monounsaturated fatty acid,MUFA)与多不饱和脂肪酸(polyunsaturated fattyacid,PUFA)的摄入量。 | 陈嘉睿(译) 练桂丽(审校) Zhuang P Zhang Y He W Chen X Chen J He L Mao L Wu F Jiao J | 2019 | 中华高血压杂志2019，27，4： | 7 |
| 6 | Introduction to the thematic issue “From brain function to therapy”显示文摘This thematic issue of Science China Life Sciences,'From brain function to therapy',highlights some of the exciting research being undertaken in the Joint Laboratory of Neuroscience and Cognition,an international scientific collaboration between the Queensland Brain Institute(QBI)at | BARTLETT Perry F HE RongQiao | 2014 | Science China(Life Sciences)2014，57，4： | 7 |
| 7 | The role of the N-methyl-D-aspartate receptor in the proliferation of adult hippocampal neural stem and precursor cells显示文摘New neurons are continuously generated from resident pools of neural stem and precursor cells(NSPCs)in the adult brain.There are multiple pathways through which adult neurogenesis is regulated,and here we review the role of the N-methyl-D-aspartate receptor(NMDAR)in regulating the proliferation of NSPCs in the adult hippocampus.Hippocampal-dependent learning tasks,enriched environments,running,and activity-dependent synaptic plasticity,all potently up-regulate hippocampal NSPC proliferation.We first consider the requirement of the NMDAR in activity-dependent synaptic plasticity,and the role the induction of synaptic plasticity has in regulating NSPCs and newborn neurons.We address how specific NMDAR agonists and antagonists modulate proliferation,both in vivo and in vitro,and then review the evidence supporting the hypothesis that NMDARs are present on NSPCs.We believe it is important to understand the mechanisms underlying the activation of adult neurogenesis,given the potential that endogenous stem cell populations have for repopulating the hippocampus with functional new neurons.In conditions such as age-related memory decline,neurodegeneration and psychiatric disease,mature neurons are lost or become defective;as such,stimulating adult neurogenesis may provide a therapeutic strategy to overcome these conditions. | TAYLOR Chanel J HE RongQiao BARTLETT Perry F | 2014 | Science China(Life Sciences)2014，57，4： | 6 |
| 8 | Expression and release of IL-29 by mast cells and modulation of mast cell behavior by IL-29显示文摘 | He, S Zhang, H Chen, H Yang, H Huang, T Chen, Y Lin, J Wang, F Chen, X Li, TL Yang, P | 2010 | 南京医科大学学报(自然科学版)2010，30，11： | 6 |
| 9 | Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg显示文摘 | He XW Wang F Jiang L Li J Liu SK Xiao ZY Jin XQ Zhang YN He Y Li K Guo YJ Sun SH | 2005 | 第二军医大学学报2005，26，10： | 5 |
| 10 | A Power and Area Optimization Approach of Mixed Polarity Reed-Muller Expression for Incompletely Specified Boolean Functions显示文摘力量和芦苇思考(RM ) 电路的区域优化广泛地被担心了。然而,几乎没有退出的力量和区域,优化来临能获得所有 Pareto 原版的最佳的答案问题并且足够有效。而且,他们没认为 dont 是照顾术语,它使电路成为性能不能进一步优化。在这糊,我们建议混合极性 RM 的一条力量和区域优化途径为不完全地指定的布尔功能的表示(MPRM ) 基于非统治的排序基因算法 II (NSGA-II ) 。第一,不完全地指定的布尔功能不完全地被转变成零极性由使用的指定 MPRM (ISMPRM ) 一篇小说 ISMPRM 获得算法。第二,极性和分配 ISMPRM 的照顾术语没作为染色体被编码。最后, Pareto 最佳的答案被使用 NSGA-II 获得,在里面哪个 MPRM 相应于给定的染色体被使用一个染色体获得变换算法。结果上重要力量和区域改进能与存在力量和区域优化相比被做的电路表演 RM 接近的不完全地指定的布尔功能和 MCNC 基准电路。 | Zhen-Xue He Li-Min Xiao Li Ruan Fei Gu Zhi-Sheng Huo Guang-Jun Qin Ming-Fa Zhu F Long-Bing Zhang Rui Liu Xiang Wang | 2017 | Journal of Computer Science & Technology2017，32，2： | 4 |
| 11 | Voltage-induced penetration effect in liquid metals at room temperature显示文摘Room-temperature liquid metal is discovered to be capable of penetrating through macro-and microporous materials by applying a voltage.The liquid metal penetration effects are demonstrated in various porous materials such as tissue paper;thick and fine sponges;fabrics;and meshes.The underlying mechanism is that the high surface tension of liquid metal can be significantly reduced to near-zero due to the voltage-induced oxidation of the liquid metal surface in a solution.It is the extremely low surface tension and gravity that cause the liquid metal to superwet the solid surface^leading to the penetration phenomena.These findings offer new opportunities for novel microfluidic applications and could promote further discovery of more exotic fluid states of liquid metals. | Frank F Yun Zhenwei Yu Yahua He Lei Jiang Zhao Wang Haoshuang Gu Xiaolin Wang | 2020 | National Science Review2020，7，2： | 3 |
| 12 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Robert F Reynolds Paul K Whelton Jiang He | 2005 | 2005 (9468)2005，，9468： | 3 |
| 13 | Effects of increased UV- B upon the ecosystem of grown wheat in China显示文摘 | Y F Zheng He Yuhong Yang Yuanyan Zhanqing Li | 2002 | Journal of Photoscience2002，9，4： | 3 |
| 14 | Expression of hepatitis B virus proteins in transgenic mice alters lipid metabolism and induces oxidative stress in the liver显示文摘 | Yang F Yan S He Y | | 0，，： | 2 |
| 15 | Prevalence of the metabolic syndrome and overweight among adults in China显示文摘 | Dongfeng Gu Kristi Reynolds Xigui Wu Jing Chen Xiufang Duan Robert F Reynolds Paul K Whelton Jiang He | 2005 | The Lancet . 2005 (9468)2005，，9468： | 2 |
| 16 | 显示文摘 | Li Y F He G F | 1998 | Synth Met1998，94，： | 2 |
| 17 | Secondary structural formation of alpha-synuclein amyloids as revealed by g-factor of solid-state circular dichroism.显示文摘 | Lin XJ Zhang F Xie YY Bao WJ He JH Hu HY | 2006 | 中国生物学文摘2006，20，9： | 2 |
| 18 | Electroneurophsysiological studies in rats of acute dimethoate poisoning 显示文摘 | Yang D Li T He F | 1999 | Toxicol Let1999，107，13： | 2 |
| 19 | Disruption of sphingolipid homeostasis by myrioein, a myeotoxin, reduces thymie and splenic T-lymphocyte populations显示文摘 | Johnson V J He Q Osuchowski M F | 2004 | Toxicology2004，201，13： | 1 |
| 20 | prognostic value of serum CA19 - 9 levels in pancreatic adenocarcinoma 显示文摘 | Tian FZ Appert HE Mules F J | | Ann Surg0，215，4： | 1 |
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