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| 1 | The use of environmentally sustainable bio-derived solvents in solvent extraction applications——A review显示文摘Replacement of volatile organic compounds(VOCs) by greener or more environmentally sustainable solvents is becoming increasingly important due to the increasing health and environmental concerns as well as economic pressures associated with VOCs.Solvents that are derived from biomass,namely bio-derived solvents,are a type of green solvent that have attracted intensive investigations in recent years because of their advantages over conventional VOCs,such as low toxicity,biodegradability and renewability.This review aims to summarize the use of bio-derived solvents in solvent extraction applications,with special emphasis given to utilization of biodiesels and terpenes.Compared with the conventional VOCs,the overall performance of these bio-derived solvents is comparable in terms of extraction yields and selectivity for natural product extraction and no difference was found for metal extraction.To date most researchers have focused on laboratory scale thermodynamics studies.Future work is required to develop and test new bio-derived solvents and understand the kinetic performance as well as solvent extraction pilot plant studies. | Zheng Li Kathryn H.Smith Geoffrey W.Stevens | 2016 | Chinese Journal of Chemical Engineering2016，24，2： | 7 |
| 2 | Carbon dioxide capture by solvent absorption using amino acids: A review显示文摘The emission of large amounts of carbon dioxide is of major concern with regard to increasing the risk of climate change. Carbon capture, utilisation and storage (CCUS) has been proposed as an important pathway for slowing the rate of these emissions. Solvent absorption of CO_2 using amino acid solvents has drawn much attention over the last few years due to advantages including their ionic nature, low evaporation rate, low toxicity, high absorption rate and high biodegradation potential, compared to traditional amine solvents. In this review, recent progress on the absorption kinetics of amino acids is summarised, and the engineering potential of using amino acids as carbon capture solvents is discussed. The reaction orders between amino acids and carbon dioxide are typ- ically between 1 and 2. Glycine exhibits a reaction order of 1, whilst, by comparison, lysine, proline and sarcosine have the largest reaction constants with carbon dioxide which is much larger than that of the benchmark solvent monoethanolamine (MEA). Ionic strength, p H and cations such as sodium and potassium have been shown to be important factors influencing the reactivity of amino acids. Corrosivity and reactivity with impurities such as SOx and NOxare not considered to be significant problems for amino acids solvents. The precipitation of CO_2 loaded amino acid salts is thought to be a good pathway for increasing CO_2loading capacity and cutting desorption energy costs if well-controlled. It is recommended that more detailed research on amino acid degradation and overall process energy costs is conducted. Overall, amino acid solvents are recognised as promising potential solvents for car- bon dioxide capture. | Guoping Hu Kathryn H.Smith Yue Wu Kathryn A.Mumford Sandra E.Kentish Geoffrey W.Stevens | 2018 | Chinese Journal of Chemical Engineering2018，26，11： | 3 |
| 3 | 潜隐性疾病风险与生命早期砷暴露的关联机制:当前的研究趋势与科学缺口显示文摘[背景]全球约有数百万人的饮用水中无机砷水平对人体有害,尤其是农村地区和发展中国家。重要生长发育时期的无机砷暴露与多种不良健康效应相关,包括成年时期出现的不良健康效应。探索生命早期的无机砷暴露与后期潜隐性疾病(尤其是癌症)之间的分子作用机制得到研究者的广泛关注。[目标]本研究汇总了现有研究发现的生命早期无机砷暴露与成年期癌症风险增加背后的分子机制。[讨论]表观遗传重编码影响了基因表达功能改变、肿瘤干细胞形成和免疫调控是生命早期无机砷暴露引起潜在致癌效应的可能机制。[结论]越来越多的证据揭示了生命早期的无机砷暴露与之后癌症的形成有关。未来的研究应通过动物实验验证致病机制的假说,同时进行人群研究将生命早期的无机砷暴露、分子改变和潜在的疾病结局整合起来。 | Kathryn A.Bailey Allan H.Smith Erik J.Tokar Joseph H.Graziano Kyoung-Woong Kim Panida Navasumrit Mathuros Ruchirawat Apinya Thiantanawat William A.Suk Rebecca C.Fry 黄馨缘(译) | 2016 | 环境与职业医学2016，33，4： | 3 |
| 4 | Prediction of dispersed phase holdup in pulsed disc and doughnut solvent extraction columns under different mass transfer conditions显示文摘Using experimental data from a number of pulsed disc and doughnut solvent extraction columns,a unified correlation for the prediction of dispersed phase holdup that considers the effects of mass transfer is presented.Pulsed disc and doughnut solvent extraction columns(PDDC) have been used for a range of important applications such as uranium extraction and nuclear fuel recycling.Although the dispersed phase holdup in a PDDC has been presented by some researchers,there is still the need to develop a robust correlation that can predict the experimental dispersed phase holdup over a range of operating conditions including the effects of mass transfer direction.In this study,dispersed phase holdup data from different literature sources for a PDDC were used to refit constants for the correlation presented by Kumar and Hartland [Ind.Eng.Chem.Res.,27(1988),131–138] which did not consider the effect of column geometry.In order to incorporate the characteristic length of the PDDC(i.e.the plate spacing),the unified correlation for holdup proposed by Kumar and Hartland based on data from eight different types of columns [Ind.Eng.Chem.Res.,34(1995) 3925–3940] was refitted to the PDDC data.New constants have been presented for each holdup correlation for a PDDC based on regression analysis using published holdup data from PDDCs that cover a range of operating conditions and physical properties and consider the direction of mass transfer. | Yong Wang Kathryn H.Smith Kathryn Mumford Teobaldo F.Grabin Zheng Li Geoffrey W.Stevens | 2016 | Chinese Journal of Chemical Engineering2016，24，2： | 3 |
| 5 | Clinical laboratory and imaging evidence for effectiveness of agarose-agarose macrobeads containing stem-like cells derived from a mouse renal adenocarcinoma cell population (RMBs) in treatment-resistant, advanced metastatic colorectal cancer:Evaluation of显示文摘Objective: The complexity, heterogeneity and capacity of malignant neoplastic cells and tumors for rapid change and evolution suggest that living-cell-based biological-systems approaches to cancer treatment are merited. Testing this hypothesis, the tumor marker, metabolic activity, and overall survival(OS) responses, to the use of one such system, implantable macrobeads [RENCA macrobeads(RMBs)], in phase I and IIa clinical trials in advanced,treatment-resistant metastatic colorectal cancer(m CRC) are described here.Methods: Forty-eight m CRC patients(30 females; 18 males), who had failed all available, approved treatments,underwent RMB implantation(8 RMB/kg body weight) up to 4 times in phase I and phase IIa open-label trials.Physicals, labs [tumor and inflammation markers, lactate dehydrogenase(LDH)] and positron emission tomography-computed tomography(PET-CT) imaging to measure number/volume and metabolic activity of the tumors were performed pre-and 3-month-post-implantation to evaluate safety and initial efficacy(as defined by biological responses). PET-CT maximum standard uptake value(SUVmax)(baseline and d 90; SUVmax ≥2.5), LDH,and carcinoembryonic antigen(CEA) and/or cancer antigen 19-9(CA 19-9) response(baseline, d 30 and/or d 60)were assessed and compared to OS.Results: Responses after implantation were characterized by an at least 20% decrease in CEA and/or CA 19-9 in75% of patients. Fluorodeoxyglucose(FDG)-positive lesions(phase I, 39; 2 a, 82) were detected in 37/48 evaluable patients, with 35% stable volume and stable or decreased SUV(10) plus four with necrosis; 10, increased tumor volume, SUV. LDH levels remained stable and low in Responders(R)(d 0–60, 290.4–333.9), but increased steadily in Non-responders(NR)(d 0–60, 382.8–1,278.5)(d 60, P=0.050). Responders to RMBs, indicated by the changes in the above markers, correlated with OS(R mean OS=10.76 months; NR mean OS=4.9 months; P=0.0006).Conclusions: The correlations of the tumor marker, tumor volume and SUV changes on PET-CT, and LDH levels themselves, and with OS, support the concept of a biological response to RMB implantation and the validity of the biological-systems approach to m CRC. A phase III clinical trial is planned. | Barry H.Smith Lawrence S.Gazda Thomas J.Fahey Angelica Nazarian Melissa A.Laramore Prithy Martis Zoe P.Andrada Joanne Thomas Tapan Parikh Sudipta Sureshbabu Nathaniel Berman Allyson J.Ocean Richard D.Hall David J.Wolf | 2018 | Chinese Journal of Cancer Research2018，30，1： | 2 |
| 6 | 神经轴突延长模型的建立显示文摘目的 建立体外延长人类神经轴突的方法 ,寻找合适的支持周围神经移植的基质材料。方法 将人胚背根神经节 (dorsalrootgangim ,DRG)神经元细胞种在胶原膜支架上 ,用自制的神经轴突延长装置对其延长至 10cm以上。观察神经元细胞及轴突的生长情况 ,测定轴突延长后轴膜的渗透性。结果 人胚神经元细胞经过延长后可保持其正常形态及维持轴膜的功能。 | 程飚 Douglas H.Smith 陈峥嵘 | 2003 | 中华手外科杂志2003，19，1： | 2 |
| 7 | 人类增强的一次热带风暴对近岸珊瑚礁的影响显示文摘土地开发以其造成的土壤加速侵蚀和迁移所产生的水体悬浮物及沉积物而成为人类对珊瑚礁的最主要的威胁。我们研究了一次热带风暴后沉积物对圣卢西亚(St.Lucia)珊瑚礁群落的影响,发现最靠近大的河流河口的珊瑚礁沉积物比较多,珊瑚损失比较大。一些地点的珊瑚死亡率超过了50%,其死亡率和褪色的程度取决于当地的沉积物数量。尽管工程师们努力降低侵蚀率,我们仍然发现风暴来临时正在修建的公路附近的地点有更多的沉积物。我们的资料表明土地开发对珊瑚礁有很大的负效应。假如土地开发的需求不断增加,并且大西洋热带地区大风暴近来频繁,问题可能会进一步加剧。 | Joshua Sladek Nowlis Callum M.Roberts Allan H.Smith Erkki Siirila 裴晓菲 | 1997 | 人类环境杂志1997，26，8： | 2 |
| 8 | Widespread Tau and Amyloid‐Beta Pathology Many Years After a Single Traumatic Brain Injury in Humans显示文摘 | Victoria E.Johnson WilliamStewart Douglas H.Smith | 2012 | Brain Pathology2012，，2： | 1 |
| 9 | Why Tugendhat's Critique of Heidegger's Concept of Truth Remains aCritical Problem显示文摘 | William H.Smith | | 0，，： | 1 |
| 10 | Computed tomography‐based tissue‐engineered scaffolds in craniomaxillofacial surgery显示文摘 | M. H.Smith C. L.Flanagan J. M.Kemppainen J. A.Sack H.Chung S.Das S. J.Hollister S. E.Feinberg | 2007 | Int. J. Med. Robotics Comput. Assist. Surg2007，，3： | 1 |
| 11 | 溢流侧堰的设计方法显示文摘假定在侧堰附近主渠的断面比能为一常数(即渠道长度很短),如图1所示,任一断面的比能为: | ALi Uyumaz Roger H.Smith 袁新明 | 1992 | 西北水资源与水工程1992，3，1： | 1 |
| 12 | Maximum Independent Sets and Supervised Learning显示文摘The paper discusses an enhancement to a recently presented supervised learning algorithm to solve the Maximum Independent Set problem.In particular,it is shown that the algorithm can be improved by simplifying the task learnt by the neural network adopted,with measurable effects on the quality of the solutions provided on unseen instances.Empirical results are presented to validate the idea.. | Roberto Montemanni Derek H.Smith Xiao-Chen Chou | 2023 | Journal of the Operations Research Society of China2023，11，4： | 1 |
| 13 | The early development of Erysiphe pisi on Pisum sativum L.显示文摘 | P. H.SMITH E. M.FOSTER L. A.BOYD J. K. M.BROWN | 2003 | Plant Pathology2003，，2： | 1 |
| 14 | In vitro approaches for studying blast-induced traumatic brain injury显示文摘 | Yung Chia Chen Douglas H.Smith David F Meaney | | 0，，03： | 1 |
| 15 | Low-Field Magnetic Sensing with GMR Sensors显示文摘 | Carl H.Smith Robert W.Schneider | | 0，，： | 1 |
| 16 | Radiation-induced oral mucositis hamster model using a linear accelerator enhances clinical relevance of preclinical studies for treatment strategy investigation显示文摘Translational animal models for oral mucositis(OM)are necessary to simulate and assess the bioclinical effects and response in humans.These models should simulate high levels of radiation exposure that leads to oxidative stress and inflammatoryinitiated tissue changes.Hamster models have been extensively studied to observe pathological effects of radiation exposure and help in the development of effective treatments.To successfully evaluate the potential for treatment regimens with consistency and relevance,a radiation-induced OM hamster model was developed using a clinical linear accelerator utilized by cancer patients daily.The dose exposure to the isolated,everted cheek pouch of a hamster,as well as the progression of injury,proinflammatory marker,histological,and elasticity analyses of the buccal pouch were conducted to verify replicability and reproducibility of the injury model.The findings from this model demonstrated its ability to consistently induce injury and resolution over 28 days using an acute dose of 60 Gy.This model was developed to enhance clinical relevance when evaluating potential efficacious treatments and can now be utilized in efficacy studies to better evaluate developed therapeutics in a preclinical model that is easy to translate to clinical studies.. | Carolyn T.Jordan Emily M.Bradford Dennis C.Cheek Mahesh Kudrimoti Craig S.Miller Molly H.Smith J.Zach Hilt Thomas D.Dziubla | 2021 | Animal Models and Experimental Medicine2021，4，1： | 1 |
| 17 | A continental back-arc setting for the Namaqua belt:Evidence from the Kakamas Domain显示文摘A study of the NW Kakamas Domain in South Africa/Namibia provides a new,unified lithostratigraphy and evolutionary history applicable to the whole Namaqua Sector.The Mesoproterozoic history ranges from~1350 Ma to 960 Ma,but isotopic evidence suggests it was built upon pre-existing Paleoproterozoic continental crust that extended west from the Archaean Craton.In eastern Namaqualand,early rift-related magmatism and sedimentation at~1350 Ma occurred in a confined ocean basin.Subsequent tectonic reversal and subduction at~1290–1240 Ma led to establishment of the Areachap,Konkiep and Kaaien Domains.In the Kakamas Domain,widespread deposition of pelitic sediments occurred at~1220 Ma(Narries Group).These contain detrital zircons derived from proximal crust with ages between~2020 Ma and 1800 Ma(western Palaeoproterozoic domains)and 1350–1240 Ma(eastern early Namaqua domains),suggesting pre-sedimentation juxtaposition.The pelites underwent granulite grade metamorphism at~1210 Ma(peak conditions:4.5–6 kbar and 770–850°C),associated with voluminous,predominantly S-type granitoid orthogneisses between~1210 Ma and 1190 Ma(Eendoorn and Ham River Suites)and low-angle ductile(D_(2))deformation which continued until~1110 Ma,interspersed with periods of sedimentation.This enduring P-T regime is inconsistent with the expected crustal over-thickening associated with the generally-accepted collision-accretion Namaqualand model.Rather,we propose the Namaqua Sector is a‘hot orogen’developed in a wide continental back-arc with subduction west of the present-day outcrop.The observed high geotherm resulted from thinned back-arc lithosphere accompanied by an influx of mantle-derived melts.Ductile D_(2)deformation resulted from'bottom-driven'tectonics and viscous drag within the crust by convective flow in the underlying asthenospheric mantle.This extended tectonothermal regime ceased at~1110 Ma when SW-directed thrusting stacked the Namaqua Domains into their current positions,constrained in the Kakamas Domain by late-to post-tectonic I-type granitoids intruded between~1125 Ma and 1100 Ma(Komsberg Suite).The thermal peak then shifted west to the Bushmanland and Aus Domains,where voluminous granites(1080–1025 Ma)were associated with high-T/low-P granulite facies thermal metamorphism and mega-scale open folding(D_(3)).Unroofing of the Namaqua Sector is marked by large-scale,NW-trending,sub-vertical transcurrent dextral shear zones and associated pegmatites and leucogranites at~990 Ma. | P.H.Macey R.J.Thomas A.F.M.Kisters J.F.A.Diener M.Angombe S.Doggart C.A.Groenewald C.W.Lambert J.A.Miller H.Minnaar H.Smith H.F.G.Moen E.Muvangua A.Nguno G.Shifotoka J.Indongo D.Frei C.Spencer P.le Roux R.A.Armstrong C.Tinguely | 2022 | Geoscience Frontiers2022，13，4： | 0 |
| 18 | 大气污染与森林显示文摘污染能对大片森林产生影响吗?能改变树种的组成吗?对某些树种、植物或动物能产生危害吗? 林业工作者有责任帮助人民来回第这些问题.虽然,今天所用的污染监测仪已是很先进的了,但要准确地回答这些问题却是困难的。控制大气污染、保护森林资源。 | WILLIOM H.SMITH 赵承开 | 1986 | 环境科学动态1986，，7： | 0 |
| 19 | 奔赴火星显示文摘“风凰号”的火星探测任务让人们重新认识这颗红色行星的宜居条件,为即将发射的新火星车铺平了遭路。 | 彼得·B·吏密斯(Peter H.Smith) 谢懿(翻译) | 2011 | 环球科学2011，，12： | 0 |
| 20 | 生命横跨“火星-地球”显示文摘是不是陨石向地球播种了生命?为了检验这个想法,我们让微生物专做第一批“旅客”。 | 彼得·H·史密斯(Peter H.Smith) 谢懿(翻译) | 2011 | 环球科学2011，，12： | 0 |
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