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| 1 | Microbleeds in fronto-subcortical circuits are predictive of dementia conversion in patients with vascular cognitive impairment but no dementia显示文摘Cerebral small vessel disease(CSVD) is a common etiology of vascular cognitive impairment with no dementia(V-CIND). Studies have revealed that cerebral microbleeds(CMBs), a feature of CSVD, contribute to cognitive impairment. However, the association between CMBs and dementia conversion in individuals with V-CIND is still unclear. Here, we analyzed the predictive role of CMBs in the conversion from V-CIND to dementia in CSVD patients. We recruited and prospectively assessed 85 patients with CSVD and V-CIND. V-CIND was evaluated using a series of comprehensive neuropsychological scales, including the Chinese version of the Montreal Cognitive Assessment and the Clinical Dementia Rating. MRI assessments were used to quantify lacunar infarcts, white matter hyperintensities, CMBs, and medial temporal lobe atrophy. Eighty-two of the 85 patients completed the assessment for dementia conversion at a 1-year follow-up assessment. Multivariate logistic regression analyses were conducted to examine independent clinical and MRI variables associated with dementia conversion. Twenty-four patients(29.3%) had converted to dementia at the 1-year follow-up, and these individuals had significantly more CMBs in the fronto-subcortical circuits. Multivariate logistic regression analyses revealed that the patients with CMBs in the fronto-subcortical circuits(odds ratio = 4.4; 95% confidence interval: 1.602–12.081, P = 0.004) and 5 or more CMBs overall(odds ratio = 17.6, 95% confidence interval: 3.23–95.84, P = 0.001) had a significantly increased risk of dementia at the 1-year follow-up. These findings indicate that CMBs in the fronto-subcortical circuits may be predictive of dementia conversion in CSVD patients with V-CIND, and thus extend the clinical significance of CMBs. | Yang-Kun Chen Wei-Min Xiao Wei Li Zhuo-Xin Ni Yong-Lin Liu Li Xu Jian-Feng Qu Chee H.Ng Yu-Tao Xiang | 2018 | Neural Regeneration Research2018，13，11： | 12 |
| 2 | 多维状态无聊量表在中国和加拿大大学生中的因素等值性研究显示文摘目的:检验多维状态无聊量表(MSBS)在中国和加拿大大学生样本中的因素等值性,并比较量表各因子在两样本间的潜均数差异。方法:使用多维状态无聊量表调查360名中国大学生和360名加拿大大学生,并对调查数据进行多组验证性因素分析。结果:量表的完全等值性不成立,依据模型修正指数和释放参数等值限制时模型拟合的改变量,发现24个设定等值的因素负荷中的6个,29个截距中的10个,29个测量残差中的6个不等值;中国大学生样本在MSBS五因子上的潜均数均显著低于加拿大大学生样本。结论:多维状态无聊量表在中国大学生样本和加拿大大学生样本间具有部分测量等值性和完全结构等值性;MSBS显均数差异不能完全由潜均数差异解释。 | 赵建芳 张守臣 刘勇 周扬 陈健芷 姜永志 Andy H.Ng John D.Eastwood | 2016 | 中国临床心理学杂志2016，24，3： | 5 |
| 3 | Adjunctive melatonin for tardive dyskinesia in patients with schizophrenia: a meta-analysis显示文摘背景:迟发性运动障碍(TD)的临床特征是异常不自主运动。TD具有严重的不可逆的致残性和社会功能损害。目的 :此荟萃分析基于随机对照试验(RCTs)文献系统评估褪黑素对精神分裂症患者迟发性运动障碍的临床疗效和安全性。方法 :两位独立评估者从以下数据库对相关的临床随机对照试验(RCT)文献进行检索(万方数据、中国知网(CNKI)、中国生物医学文摘数据库和PubM ed、PsycI NFO、Embase、Cochrane Library数据库),检索时间截止于2017年6月8日。以TD症状严重程度为主要结局指标,采用Rev Man 5.3版本进行统计分析,对RCTs的质量评估采用Cochrane风险评估偏倚和Jadad量表来评估各种偏倚的风险性。采用GRADE(Grades of Recommendation,Assessment,Development,and Evaluation)系统推荐分级方法对meta-分析结果的整体证据质量水平进行分级评价。结果 :最终筛选确定4个RCTs(n=130)。3个RCTs采用双盲法,1个RCT单盲,根据Cochrane风险评估偏倚和Jadad量表显示3个RCTs的疗效评估指标的证据质量被评定为'高质量'。与对照组相比,根据不自主运动量表(AIMS)评定褪黑素可改善TD严重程度(4个RCTs,n=130,加权平均差值(WMD):-1.52(95%CI:-3.24,0.20),p=0.08;I2=0%),但尚没有达到显著差异。根据等级方法,改善TD症状的meta分析结果的整体证据质量被评为'低',而关于不良反应和认知损害方面则数据太少。结论 :荟萃分析表明,褪黑素或可改善精神分裂症TD症状。但仍有待今后更高质量和更大样本的RCTs验证。 | 孙辰辉 郑伟 杨欣湖 蔡东滨 Chee H.NG Gabor S.UNGVARI 李海燕 吴玉洁 宁玉萍 项玉涛 | 2017 | 上海精神医学2017，29，3： | 5 |
| 4 | 抑郁症状快速评定量表自评版(QIDS-SR)应用于HBV相关肝脏疾病患者的心理测量学特性(英文)显示文摘背景:乙型肝炎病毒(HBV)感染伴发抑郁症是一种常见的现象。建立精确并且有时效的工具,用以评估HBV患者抑郁症状,对研究和临床实践是非常重要的。目的:这项研究测试了抑郁症状快速评定量表自评版(QIDS-SR)在乙型肝炎患者中使用的心理测量学特性。方法:这项研究招募了245名患有乙型肝炎病毒和相关肝病的抑郁症患者。采用蒙特玛莉抑郁评定量表(MADRS)和QIDS-SR评估抑郁症状的严重程度。结果:QIDS-SR的内部一致性((Cronbachα)为0.796.其总分与MADRS总分显著相关r=0.698,p<0.001)。探索性因素分析的QIDS-SR显示一维测量性能结论:QIDS-SR(中文版)在乙型肝炎患者中有良好的心理测量学特性,并且在评估临床抑郁症方面是有用的。 | 刘梅 王园园 赵景 郑素军 Gabor S.UNGVARI Chee H.NG 段钟平 项玉涛 | 2017 | 上海精神医学2017，29，1： | 5 |
| 5 | Determinants of job mobility: A theoretical integration and extension显示文摘 | Thomas W. H.Ng Kelly L.Sorensen Lillian T.Eby Daniel C.Feldman | 2010 | Journal of Occupational and Organizational Psychology2010，，3： | 2 |
| 6 | An Overview of the Expert Consensus on the Prevention and Treatment of Gaming Disorder in China(2019 Edition)显示文摘Gaming disorder has gained considerable attention worldwide,including in China[1],where epidemiological surveys have found that its prevalence is as high as 17%[2].The Bureau of Disease Control and Prevention run by the National Health and Health Commission in China recently released an expert consensus[2]that systematically describes the definition,clinical presentation,assess-assessment,diagnosis,treatment,rehabilitation,and related areas of gaming disorder. | Yu-Tao Xiang Yu Jin Ling Zhang Lu Li Gabor S.Ungvari Chee H.Ng Min Zhao Wei Hao | 2020 | Neuroscience Bulletin2020，36，7： | 2 |
| 7 | Employee voice behavior: A meta‐analytic test of the conservation of resources framework显示文摘 | Thomas W. H.Ng Daniel C.Feldman | 2012 | J Organiz Behav2012，，2： | 2 |
| 8 | Long work hours: a social identity perspective on meta‐analysis data显示文摘 | Thomas W. H.Ng Daniel C.Feldman | 2008 | J Organiz Behav2008，，7： | 1 |
| 9 | PREDICTORS OF OBJECTIVE AND SUBJECTIVE CAREER SUCCESS: A META‐ANALYSIS显示文摘 | THOMAS W. H.NG LILLIAN T.EBY KELLY L.SORENSEN DANIEL C.FELDMAN | 2005 | Personnel Psychology2005，，2： | 1 |
| 10 | PREDICTORS OF OBJECTIVE AND SUBJECTIVE CAREER SUCCESS: A META‐ANALYSIS显示文摘 | THOMAS W. H.NG LILLIAN T.EBY KELLY L.SORENSEN DANIEL C.FELDMAN | 2005 | Personnel Psychology2005，，2： | 1 |
| 11 | Clopidogrel plus omeprazole compared with aspirin plus omeprazole for aspirin‐induced symptomatic peptic ulcers/erosions with low to moderate bleeding/re‐bleeding risk — a single‐blind, randomized controlled study显示文摘 | F.‐H.Ng B. C.‐Y.Wong S.‐Y.Wong W.‐H.Chen C.‐M.Chang | 2004 | Alimentary Pharmacology & Therapeutics2004，，3： | 1 |
| 12 | Predictors of the placebo response in a nutraceutical randomized controlled trial for depression显示文摘Objective The placebo response in depression studies is the change in symptoms amongst those who receive an inactive treatment.Many well-designed randomized controlled trials(RCTs)of depression have a high proportion of placebo responders,with little understanding as to why.The present study assesses characteristics associated with the placebo response in a nutraceutical trial with a large proportion of placebo responders.Methods This is a secondary analysis of a nutraceutical depression RCT which identified no overall treatment benefit relative to placebo(n=69 in placebo group).We investigated participant characteristics such as socio-demographics,clinical features,and recruitment methods,and their association with the placebo response.Monoaminergic genetic polymorphisms were also assessed.Placebo response was measured based on change in Montgomery-Asberg Depression Rating Scale score.The association of these hypothesis-driven variables of interest and the placebo response was examined using linear mixed effects models.Results Greater levels of education,particularly pursuing post-high school education,better self-reported general health,marriage/de facto,greater improvement in the first trial week,and more failed antidepressant therapies in the current depressive episode were associated with greater placebo response.An increased placebo response was not found in those recruited via social media nor in those with concomitant antidepressant therapy.Single nucleotide polymorphisms from the tryptophan hydroxylase 1(TPH1)gene(A779C and A218C)were weakly associated with greater placebo response,although the evidence was attenuated after accounting for multiple comparisons.Conclusion This is,to our knowledge,the first study within nutraceutical research for depression to assess the association between participant characteristics and variation in the placebo response.Several variables appeared to predict the placebo response.Such findings may encourage future trial designs which could dampen placebo response,improve assay sensitivity,and allow for treatment effects to be potentially more detectable. | Rosemary Arnold Jenifer Murphy-Smith Chee H.Ng David Mischoulon Gerard J.Byrne Chad A.Bousman Con Stough Michael Berk Jerome Sarris | 2024 | Journal of Integrative Medicine2024，22，1： | 0 |
| 13 | FCC coprocessing oil sands heavy gas oil and canola oil. 2. Gasoline hydrocarbon type analysis显示文摘This study set out to gain a deeper understanding of a fluid catalytic cracking(FCC)coprocessing approach using canola oil mixed with bitumen-derived heavy gas oil(HGO),for the production of partially-renewable gasoline,with respect to its composition and quality.The FCC coprocessing approach may provide an alternative solution to reducing the carbon footprint and to meet government regulatory demands for renewable transportation fuels.In this study,a mixture of 15 v%canola oil in HGO was catalytically cracked with a commercial equilibrium catalyst under typical FCC conditions.Cracking experiments were performed using a bench-scale Advanced Cracking Evaluation(ACE)unit at a fixed weight hourly space velocity of 8 h^(à1),490–530C,and catalyst/oil ratios of 4–12 g/g.The total liquid product samples were injected via an automatic sampler and a prefractionator(to removet254C)into a gas chromatographic system containing a series of columns,traps,and valves designed to separate each of the hydrocarbon types.The analyzer gives detailed hydrocarbon types of à200C gasoline,classified into paraffins,iso-paraffins,olefins,naphthenes,and aromatics by carbon number up to C_(11)(C_(10)for aromatics).For a feed cracked at a given temperature,the gasoline aromatics show the highest selectivity in terms of weight percent conversion,followed by saturated iso-paraffins,saturated naphthenes,unsaturated iso-paraffins,unsaturated naphthenes,unsaturated normal paraffins,and saturated normal paraffins.As conversion increases,both aromatics and saturated iso-paraffins increase monotonically at the expense of other components.Hydrocarbon type analysis and octane numbers with variation in feed type,process severity(temperature and catalyst/oil ratio),and conversion are also presented and discussed. | Siauw H.Ng Nicole E.Heshka Cecile Lay Edward Little Ying Zheng Qiang Wei Fuchen Ding | 2018 | Green Energy & Environment2018，3，3： | 0 |
| 14 | 用原位腔内清洗提高Al刻蚀的MTBC显示文摘优化原位腔清洗工艺可延长清洗之间Al刻蚀腔加工时间(MTBC),不损伤清洗腔内部,同时也保持了合理的产额。Cl/O2能非常有效地去除碳基聚合物,而BCl3/Cl最有利于去除Al副产品。通过提高压力得到了顶盖/侧壁清洗均匀性方面最好的改进。实行最佳清洗工艺后,MTBC提高了4倍。 | F.Chen Y.Huang Q.Ge H.Ng | 2013 | 功能材料与器件学报2013，19，5： | 0 |
| 15 | FCC coprocessing oil sands heavy gas oil and canola oil. 3. Some cracking characteristics显示文摘Coprocessing of bitumen-derived feeds and biomass through a fluid catalytic cracking(FCC) route has the potential to assist in the reduction of fuel and petroleum product carbon footprints while meeting government regulatory requirements on renewable transportation fuels. This approach is desirable because green house gas(GHG) emissions for producing renewable biofuels are significantly lower than those for fossil fuels, and coprocessing can be executed using existing refining infrastructure to save capital cost. The present study investigates the specific FCC performances of pure heavy gas oil(HGO) derived from oil sands synthetic crude, and a mixture of 15 v% canola oil in HGO using a commercial equilibrium catalyst under typical FCC conditions. Cracking experiments were performed using a bench-scale Advanced Cracking Evaluation(ACE) unit at fixed weight hourly space velocity(WHSV) of 8 h^(-1), 490–530℃, and catalyst/oil ratios of 4–12 g/g. This work focuses on some cracking phenomena resulting from the presence of oxygen in the blendda lower heat requirement for cracking due to the exothermic water formation, which also entails lower hydrogen yield at a given severity. The distribution of feed oxygen in gaseous and liquid products, the mitigation in GHG emissions, and the technological and economical advantages of the coprocessing option are also discussed. | Siauw H.Ng Nicole E.Heshka Ying Zheng Qiang Wei Fuchen Ding | 2019 | Green Energy & Environment2019，4，1： | 0 |
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