维普中文期刊产品整合服务
5篇 您的检索式:作者名="Con Stough"
    题名 作者 年代 出处 被引量
1Acute effects of tea constituents L‐theanine, caffeine, and epigallocatechin gallate on cognitive function and mood: a systematic review and meta‐analysis显示文摘David A Camfield Con Stough Jonathon Farrimond Andrew B Scholey 2014Nutr Rev2014,,8:1
2Emotional intelligence and life satisfaction显示文摘 CATHERINE DONALDSON CON STOUGH 2002Personality and Individual Differences2002,33,:1
3Emotional Intelligence and Life Satisfaction 显示文摘Benjamin Palmer Catherine Donaldson Con Stough 2002Personality and Indi- vidual Difference2002,,33:1
4Deficits in emotional intelligence underlying adolescent sex offending显示文摘Nicole Moriarty Con Stough 2001Journal of Adolescence2001,24,:1
5Predictors of the placebo response in a nutraceutical randomized controlled trial for depression显示文摘Objective The placebo response in depression studies is the change in symptoms amongst those who receive an inactive treatment.Many well-designed randomized controlled trials(RCTs)of depression have a high proportion of placebo responders,with little understanding as to why.The present study assesses characteristics associated with the placebo response in a nutraceutical trial with a large proportion of placebo responders.Methods This is a secondary analysis of a nutraceutical depression RCT which identified no overall treatment benefit relative to placebo(n=69 in placebo group).We investigated participant characteristics such as socio-demographics,clinical features,and recruitment methods,and their association with the placebo response.Monoaminergic genetic polymorphisms were also assessed.Placebo response was measured based on change in Montgomery-Asberg Depression Rating Scale score.The association of these hypothesis-driven variables of interest and the placebo response was examined using linear mixed effects models.Results Greater levels of education,particularly pursuing post-high school education,better self-reported general health,marriage/de facto,greater improvement in the first trial week,and more failed antidepressant therapies in the current depressive episode were associated with greater placebo response.An increased placebo response was not found in those recruited via social media nor in those with concomitant antidepressant therapy.Single nucleotide polymorphisms from the tryptophan hydroxylase 1(TPH1)gene(A779C and A218C)were weakly associated with greater placebo response,although the evidence was attenuated after accounting for multiple comparisons.Conclusion This is,to our knowledge,the first study within nutraceutical research for depression to assess the association between participant characteristics and variation in the placebo response.Several variables appeared to predict the placebo response.Such findings may encourage future trial designs which could dampen placebo response,improve assay sensitivity,and allow for treatment effects to be potentially more detectable.Rosemary Arnold Jenifer Murphy-Smith Chee H.Ng David Mischoulon Gerard J.Byrne Chad A.Bousman Con Stough Michael Berk Jerome Sarris 2024Journal of Integrative Medicine2024,22,1:0
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费