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1008篇 您的检索式:作者名="Gupta C P"
    题名 作者 年代 出处 被引量
1A Sharper Condition for the Solvability of a Three-point Second-order Boundary Value Problem 显示文摘Gupta C P 1997J Math Anal Appl1997,205,2:3
2Combination immunotherapy with Survivin and luteinizing hormone-releasing hormone fusion protein in murine breast cancer model显示文摘AIM To investigate the therapeutic potential of two recombinant proteins, Survivin and luteinizing hormone-releasing hormone (LHRH) fusion protein [LHRH(6 leu)-LTB] for immunotherapy of breast cancer.METHODS Murine 4 T-1 breast cancer model was used to evaluate the efficacy of recombinant proteins in vivo. Twenty four Balb/c mice were divided into 4 groups of 6 mice each. Recombinant Survivin and LHRH fusion protein, alone or in combination, were administered along with immunomodulator Mycobacterium indicus pranii (MIP) in Balb/c mice. Unimmunized or control group mice were administered with phosphate buffer saline. Each group was then challenged with syngeneic 4 T-1 cells to induce the growth of breast tumor. Tumor growth was monitored to evaluate the efficacy of immune-response in preventing the growth of cancer cells.RESULTS Preventive immunization with 20 μg recombinant Survivin and MIP was effective in suppressing growth of 4 T-1 mouse model of breast cancer (P = 0.04) but 50 μg dose was ineffective in suppressing tumor growth. However, combination of Survivin and LHRH fusion protein was more effective in suppressing tumor growth (P = 0.02) as well as metastasis in vivo in comparison to LHRH fusion protein as vaccine antigen alone.CONCLUSION Recombinant Survivin and MIP suppress tumor growth significantly. Combining LHRH fusion protein with Survivin and MIP enhances tumor suppressive effects marginally which provides evidence for recombinant Survivin and LHRH fusion protein as candidates for translating the combination cancer immunotherapy approaches.Himani Garg Rohit Singh Hada Jagdish C Gupta G P Talwar Shweta Dubey 2018World Journal of Clinical Oncology2018,9,8:2
3Relations for reliability measures under length biased sampling显示文摘GUPTA R C KEATING J P 1986Scandinavian Journal of Statistics1986,13,:1
4A Sharper Condition for the Solvability of a Three-point Second Order Boundary Value Problem显示文摘Gupta C P 1997J Math Anal Appl1997,205,:1
5T ( p-e)/QT ratio as an index of arrhythmogenesis 显示文摘Gupta P Pate1 C Patel H 2008J Electrocardiol2008,41,6:1
6Solvability of a three-point nonlinear boundary value problem for a second order ordinary differential equations显示文摘GUPTA C P 1992J Math Anal Appl1992,168,:1
7On the moments of residual life in reliability and some characterization results 显示文摘GUPTA P L GUPTA R C 1983Communications in Statistics1983,12,4:1
8Molecular markers and their applications in wheat breeding显示文摘P K Gupta R K Varshney P C Sharma B Ramesh 1999Plant Breeding1999,118,:1
9Probabilistic assessment of financial losses caused by interruptions and voltage sags: part Ⅰ-the methodology显示文摘Milanovic J V Gupta C P 2006IEEE Trans on Power Develivery2006,21,2:1
10Tp-e/QT ratio as an index of ar- rhythmogenesis显示文摘Gupta P Patel C Patel H 2008J Electrocardiol2008,41,6:1
11Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 sig- naling显示文摘Fillmore C M Gupta P B Rudnick J A 2010Proc Natl Acad Sci USA2010,107,21:1
12Deposition, exhumation, and paleoclimate of an ancient lake deposit, Gale crater, Mars 显示文摘GROTZINGER J P GUPTA S MALIN M C 2015Science2015,350,6257:1
13Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion 显示文摘Orimo A Gupta P B Sgroi D C 2005Cell2005,121,3:1
14Thermal-Mechanical Modeling of the Rolling-Plus-Sliding with Frictional Heating of a Locomotive Wheel 显示文摘Gupta V Hahn G T Bostias P C et aI 1995Transactions of ASME1995,117,8:1
15A sharper condition for the solvability of a three-point second order boundary value problem显示文摘GUPTA C P Trofimchuk S I 1997J Math Anal Appl1997,205,:1
16Probabilistic assessment of financial Iossesdue to interruptions and voltage sags-part Ⅱ: practical implementation显示文摘Milanovic J V Gupta C P 2006IEEE Trans on Power Develivery2006,21,2:1
17Three-to six-year follow-up of stand-alone BAK cages implanted by a single surgeon 显示文摘Button G Gupta M Barrett C Cammack P Benson D 2005Sline J2005,5,:1
18Mediators of vascular remodelling co-opted for sequential steps in lung metastasis 显示文摘Gupta G P Nguyen D X Chiang A C 2007Nature2007,446,7137:1
19Existence and uniqueness theorem for a bending of an elastic beam equation显示文摘Gupta C P 1988Applicable A- nalysis1988,26,4:1
20Oxy-fuel combustion technology for coal-fired power generation显示文摘BUHRE B J P ELLIOTT L K SHENG C D GUPTA R P WALL T F 2005Prog Energy Combust2005,31,4:1
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