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| 1 | Neopterin, a prognostic marker in human malignancies显示文摘 | Robert Sucher Katharina Schroecksnadel Guenter Weiss Raimund Margreiter Dietmar Fuchs Gerald Brandacher | 2009 | Cancer Letters2009，，1： | 2 |
| 2 | Mechanisms of plasma non‐transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients显示文摘 | John B. Porter Patrick B. Walter Lynne D. Neumayr Patricia Evans Sukhvinder Bansal Maciej Garbowski Marcela G. Weyhmiller Paul R. Harmatz John C. Wood Jeffery L. Miller Colleen Byrnes Guenter Weiss Markus Seifert Regine Grosse Dagmar Grabowski Angelica Sc | 2014 | Br J Haematol2014，，5： | 1 |
| 3 | Anemia of chronic disease显示文摘 | Guenter Weiss Lawrence T Goodnough | 2005 | The new England Journal of Medicine2005，10，10： | 1 |
| 4 | Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression显示文摘 | Milan Theurl Igor Theurl Kathrin Hochegger Peter Obrist Nathan Subramaniam Nico Rooijen Klaus Schuemann Guenter Weiss | 2008 | Journal of Molecular Medicine2008，，7： | 1 |
| 5 | Occult celiac disease prevents penetrance of hemochromatosis显示文摘AIM: To report a patient with C282Y homozygocity, depleted body iron and intestinal atrophy caused by celiac disease (CD) who experienced resolution of the enteropathy with subsequent normalization of iron metabolism upon glutenfree diet.METHODS: To obtain information on the tissue distribution and quantitative expression of proteins involved in duodenal iron trafficking, we determined the expression of divalent-metal transporter 1 (DMT1), ferroportin 1 (FP1) and transferrin receptor (TfR1) by means of immunohistochemistry and real-time PCR in duodenal biopsies of this patient.RESULTS: Whereas in hereditary hemochromatosis patients without CD, DMT1 expression was up-regulated leading to excessive uptake of iron, we identified a significant reduction in protein and mRNA expression of DMT1 as acompensatory mechanism in this patient with HH and CD.CONCLUSION: Occult CD may compensate tot increased DMT1 expression in a specific subset of individuals withhomozygous C282Y mutations in the hemochromatosis(HFE) gene, thus contributing to the low penetrance of HH. | Andreas Geier Carsten Gartung Igor Theurl Guenter Weiss Frank Lammert Christoph G.Dietrich Ralf Weiskirchen Heinz Zoller Benita Hermanns Siegfried Matern | 2005 | World Journal of Gastroenterology2005，11，21： | 0 |
| 6 | Nanoscale chemical imaging of individual chemotherapeutic cytarabineloaded liposomal nanocarriers显示文摘Dosage of chemotherapeutic drugs is a tradeoff between efficacy and side-effects.Liposomes are nanocarriers that increase therapy efficacy and minimize side-effects by delivering otherwise difficult to administer therapeutics with improved efficiency and selectivity.Still,variabilities in liposome preparation require assessing drug encapsulation efficiency at the single liposome level,an information that,for non-fluorescent therapeutic cargos,is inaccessible due to the minute drug load per liposome.Photothermal induced resonance (PTIR) provides nanoscale compositional specificity,up to now,by leveraging an atomic force microscope (AFM) tip contacting the sample to transduce the sample's photothermal expansion.However,on soft samples (e.g.,liposomes) PTIR effectiveness is reduced due to the likelihood of tip-induced sample damage and inefficient AFM transduction.Here,individual liposomes loaded with the chemotherapeutic drug cytarabine are deposited intact from suspension via nano-electrospray gas-phase electrophoretic mobility molecular analysis (nES-GEMMA) collection and characterized at the nanoscale with the chemically-sensitive PTIR method.A new tapping-mode PTIR imaging paradigm based on heterodyne detection is shown to be better adapted to measure soft samples,yielding cytarabine distribution in individual liposomes and enabling classification of empty and drug-loaded liposomes.The measurements highlight PTIR capability to detect ~ 103 cytarabine molecules (~ 1.7 zmol) label-free and non-destructively. | Karin Wieland Georg Ramer Victor U. Weiss Guenter Allmaier Bemhard Lendl Andrea Centrone | 2019 | Nano Research2019，12，1： | 0 |
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