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| 1 | Identifying more reliable parameters for the detection of change during the follow-up of mild to moderate keratoconus patients显示文摘Background:Reaching a consensus on which parameters are most reliable at detecting progressive keratoconus patients with serial topography imaging is not evident.The aim of the study was to isolate the parameters best positioned to detect keratoconus progression using the Pentacam HR^(®)measures based on the respective limits of repeatability and range of measurement.Method:Using the Pentacam HR^(®),a tolerance index was calculated on anterior segment parameters in healthy and keratoconic eyes.The tolerance index provides a scale from least to most affected parameters in terms of measurement noise relative to that observed in healthy eyes.Then,based on the“number of increments”from no disease to advanced disease,a relative utility(RU)score was also calculated.RU values close to 1 indicate parameters best positioned to detect a change in keratoconic eyes.Results:The tolerance index values indicated that 36%of ocular parameters for keratoconic eyes had repeatability limits which were wider than normative limits(worse),but 28%of the ocular parameters were narrower than normative limits(better).Considering only those parameters with a RU greater than 0.95,a small number of parameters were within this range,such as corneal curvature and asphericity indices.Conclusions:This study demonstrates that measurement error in keratoconic eyes is significantly greater than healthy eyes.Indices implemented here provide guidance on the levels of expected precision in keratoconic eyes relative to healthy eyes to aid clinicians in distinguishing real change from noise.Importantly maximal keratometry(Kmax),central corneal thickness(CCT)and thinnest corneal thickness(TCT)were highlighted as problematic indices for the follow-up of keratoconus in terms of repeatability. | Ivo Guber Colm McAlinden François Majo Ciara Bergin | 2017 | Eye and Vision2017，4，1： | 6 |
| 2 | Predictability of refraction following immediate sequential bilateral cataract surgery(ISBCS)performed under general anaesthesia显示文摘Background:To evaluate the predictability of refraction following immediate sequential bilateral cataract surgery(ISBCS)performed under general anaesthesia.Methods:This is a retrospective review of all ISBCS performed at Kantonsspital Winterthur,Switzerland,between April 2000 and September 2013.The case notes of 250 patients were reviewed.Patients having full refraction reported(110 patients/220 eyes)were included.210(95%)eyes had a straight forward phacoemulsification with posterior chamber intraocular lens implantation,seven eyes had a planned extracapsular cataract extraction(ECCE);three eyes had an intracapsular cataract extraction.Results:Both eyes of 110 patients(64 women,46 men)with a mean age of 79.0 years,standard deviation(SD)±11.4(range 26 to 97 years)were included.Median preoperative best corrected visual acuity(BCVA)was 0.5 LogMAR in the first eye,the interquartile range(IQR)was[0.4,1.2];0.7 LogMAR in the second eye with IQR[0.4,1.8].At one month,the median BCVA was 0.2 LogMAR,IQR[0.1,0.3]in the first eye,median BCVA was 0.1 LogMAR and IQR[0.0,0.5]in the second eye.There were 3 eyes(3%)that lost 3 lines or more in BCVA at one month(control vs.pre-operatively).In all three cases,poor visual acuity had been recorded pre-operatively(>1 LogMAR).Achieved refraction was within±1.0 D of the target in 83%of eyes.There were only 5%(n=6)of cases where if delayed sequential bilateral extraction had been performed could potentially intraocular lens(IOL)choice have been adjusted,in four of these cases,target refraction was within±1.0 D in the second eye.Conclusions:ISBCS performed under general anaesthesia achieves target refraction in 83%of eyes after consideration of complications,ocular co-morbidities and systemic restrictions.In the majority of cases where IOL power calculation could be considered,the achieved refraction of the second surgical eye was within±1.0 D of intended refraction.This undermines the utility of IOL power adjustments in the second surgical eye. | Ivo Guber Laurent Rémont Ciara Bergin | 2015 | Eye and Vision2015，2，1： | 3 |
| 3 | ENDF/B-VII.1 Nuclear Data for Science and Technology: Cross Sections, Covariances, Fission Product Yields and Decay Data显示文摘 | M.B. Chadwick M. Herman P. Oblo?insky M.E. Dunn Y. Danon A.C. Kahler D.L. Smith B. Pritychenko G. Arbanas R. Arcilla R. Brewer D.A. Brown R. Capote A.D. Carlson Y.S. Cho H. Derrien K. Guber G.M. Hale S. Hoblit S. Holloway T.D. Johnson T. Kawano B.C. Kiedr | 2011 | Nuclear Data Sheets2011，，12： | 2 |
| 4 | Hybrid open-endovascular repair for thoracoabdominal aortic aneurysms:current status and level of evidence显示文摘 | Donas KP Czerny M Guber I | 2007 | Eur J Vasc Endovasc Surg2007，34，5： | 1 |
| 5 | Environmental Concem and the Dimensionality Problem: A New Approach to an Old Predicament显示文摘 | Guber Deborah L | 1996 | Social Science Quarterly1996，，77： | 1 |
| 6 | Microfabrication of single-use plastic microfluidic devices for high-throughput screening and DNA analysis 显示文摘 | GERLACH A KNEBEL G GUBER A E | 2002 | Microsystem Technologies2002，7，： | 1 |
| 7 | Soil aggregates and water retention 显示文摘 | Paehepsky Y Rawls W Guber A | 2004 | Developments in Soil Science2004，30，8： | 1 |
| 8 | Fractal mass-size scaling of wetting soil aggregates显示文摘 | Guber A K Pachepsky Y A Levkovsky E V | 2005 | Ecological Modelling2005，182，34： | 1 |
| 9 | Fractal mass–size scaling of wetting soil aggregates显示文摘 | A.K. Guber Ya.A. Pachepsky E.V. Levkovsky | 2004 | Ecological Modelling2004，，3： | 1 |
| 10 | Endovascular repair of extracranial carotid artery dissection: current status and level of evidence显示文摘 | Donas KP Mayer D Guber I | 2008 | J Vase Interv Radiol2008，19，12： | 1 |
| 11 | Senescence in cells of the aging and degener ating intervertebral disc:immunolocalization of senescence-associated beta-galactosidase in human and sand rat discs显示文摘 | Guber Helen E | 2007 | Spine2007，32，3： | 1 |
| 12 | Applicability of risk scores for postoperative nausea and vomiting in adults to paediatric patients 显示文摘 | Eberhart LH Morin AM Guber D | 2004 | Br J Anaesth2004，93，3： | 1 |
| 13 | Effect of manure on Escherichia coli attachment to soil显示文摘 | Guber A.K Shelton D.R Pachepsky Y.A | | 0，，： | 1 |
| 14 | Multifractal modeling of soil microtopography with multiple transects data显示文摘 | F. San José Martínez J. Caniego A. Guber Y. Pachepsky M. Reyes | 2009 | Ecological Complexity2009，，3： | 1 |
| 15 | Dynamic mitochondrial- nuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiation 显示文摘 | Toneatto J Guber S Charo N L | 2013 | J Cell Sci2013，126，23： | 1 |
| 16 | High-voltage contactless conductivity-detection for lab-on-chip devices using external electrodes on the holder显示文摘 | TANYANYIWA J ABAD-VILLAR E M FERNNDEZ-ABEDUL M T COSTA-GARC I'A A HOFFMANN W GUBER A E HERRMANN D GERLACH A GOTTSCHLICH N HAUSER P C | 2003 | Analyst2003，128，8： | 1 |
| 17 | Hybrid Open-endovascular Repair for Thoracoabdominal Aortic Aneurysms: Current Status and Level of Evidence显示文摘 | K.P. Donas M. Czerny I. Guber H. Teufelsbauer J. Nanobachvili | 2007 | European Journal of Vascular & Endovascular Surgery2007，，5： | 1 |
| 18 | Higher incidence of retinal pigment epithelium tears after ranibizumab in neovascular age-related macular degeneration with increasing pigment epithelium detachment height 显示文摘 | Guber J Praveen A Saeed MU | 2013 | Br J Ophthalmol2013，97，11： | 1 |
| 19 | Microfluidic Lab-- on-- a-- chip Systems Based on Polymers Fabrication and Application 显示文摘 | Guber A E Heckele M Herrmann D | 2004 | Chemical Engineering Journal2004，101，13： | 1 |
| 20 | Temporal stability in soil water content patterns across agricultural fields显示文摘 | Guber A K Gish T J Pachepsky Y A | 2007 | CATENA2007，09，010： | 1 |
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