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| 1 | Labile Organic Matter Content and Distribution as Affected by Six-year Soil Amendments to Eroded Chinese Mollisols显示文摘Labile organic carbon(LOC)is a fraction of soil organic carbon(SOC)with rapid turnover time and is affected by soil fertilization.This investigation characterized the SOC content,LOC content and LOC distribution in the treatment plots of surface soil erosion at five levels(0-,5-,10-,20-and 30-cm erosion).The soil had received contrasting fertilizer treatments(i.e.,chemical fertilizer or chemical fertilizer+manure)for 6 years.This study demonstrated that both SOC and various LOC fractions contents were higher in the plots with fertilizer+manure than in those with fertilizer alone under the same erosion conditions.The SOC and LOC contents decreased as the erosion depth increased.Light fraction organic carbon,particulate organic carbon,easily oxidizable organic carbon(KMnO4-oxydizable organic carbon),and microbial biomass carbon were 27%–57%,37%–47%,20%–25%,and 29%–33%higher respectively in the fertilizer+manure plots,than in the fertilizer alone plots.Positive correlations(p<0.05)between SOC content and different fractions contents were observed in all plots except the correlation between total SOC content and water-soluble organic carbon content in the different fertilization treatments.Obviously,fertilizer+manure treatments would be conducive to the accumulation of LOC and SOC in the Black soil of Northeast China. | SUI Yueyu JIAO Xiaoguang CHEN Wenting LIU Xiaobing ZHANG Xingyi DING Guangwei | 2013 | Chinese Geographical Science2013，23，6： | 7 |
| 2 | Regorafenib-loaded poly(lactide-co-glycolide) microspheres designed to improve transarterial chemoembolization therapy for hepatocellular carcinoma显示文摘Transarterial chemoembolization(TACE)has been widely introduced to treat hepatocellular carcinoma(HCC)especially for unresectable patients for decades.However,TACE evokes an angiogenic response due to the secretion of vascular endothelial growth factor(VEGF),resulting in the formation of new blood vessels and eventually tumor recurrence.Thus,we aimed to develop regorafenib(REGO)-loaded poly(lactide-co-glycolide)(PLGA)microspheres that enabled localized and sustained drug delivery to limit proangiogenic responses following TACE in HCC treatment.REGO-loaded PLGA microspheres were prepared using the emulsion-solvent evaporation/extraction method,in which DMF was selected as an organic phase co-solvent.Accordingly,we optimized the proportion of DMF,which the optimal ratio to DCM was 1:9(v/v).After preparation,the microspheres provided high drug loading capacity of 28.6%,high loading efficiency of 91.5%,and the average particle size of 149μm for TACE.IR spectra and XRD were applied to confirming sufficient REGO entrapment.The in vitro release profiles demonstrated sustained drug release of microspheres for more than 30 d To confirm the role of REGO-loaded microspheres in TACE,the cell cytotoxic activity on HepG2 cells and anti-angiogenic effects in HUVECs Tube-formation assay were studied in combination with miriplatin.Moreover,the microspheres indicated the potential of antagonizing miriplatin resistance of HepG2 cells in vitro.Pharmacokinetics preliminary studies exhibited that REGO could be sustainably released from microspheres for more than 30d after TACE in vivo.In vivo anti-tumor efficacy was further determined in HepG2 xenograft tumor mouse model,demonstrating that REGO microspheres could improve the antitumor efficacy of miriplatin remarkably compared with miriplatin monotherapy.In conclusion,the obtained REGO microspheres demonstrated promising therapeutic effects against HCC when combined with TACE. | Xiang Li Guangwei He Feng Su Zhaoxing Chu Leiming Xu Yazhong Zhang Jianping Zhou Yang Ding | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，6： | 4 |
| 3 | Polluted lake restoration to promote sustainability in the Yangtze River Basin,China显示文摘China has sought to address water pollution in the last decade by introducing a wide range of laws and regulations(Table S1), which led to nationwide water quality improvement ^([1]). However, recent quantitative assessment of progress toward Sustainable Development Goals (SDGs) in China suggests that some SDGs underpinning goals for water pollution and biodiversity have not been met ^([2]). | Boqiang Qin Yunlin Zhang Jianming Deng Guangwei Zhu Jianguo Liu David P.Hamilton Hans W.Paerl Justin D.Brookes Tingfeng Wu Kai Peng Yizhou Yao Kan Ding Xiaoyan Ji | 2022 | National Science Review2022，9，1： | 4 |
| 4 | Numerical and test study on vertical vibration characteristics of pile group in slope soil topography显示文摘Topography effects on the vertical vibration responses of pile group are revealed though numerical analysis and model tests.First,a series of model tests with different topography of ground and bedrock are conducted.The results indicate that displacement amplitude of the pile head in sloping ground topography is larger than in horizontal ground.Differential displacement at various positions of the pile cap is observed in non-horizontal topography.Afterwards,a numerical algorithm is employed to further explore the essential response characteristics in group piles of different topography configurations,which has been verified by the test results.The lengths of the exposed and frictional segment,together with the thickness of the subsoil layer,are the dominant factors which cause non-axisymmetric vibration at the pile cap. | Qu Liming Ding Xuanming Zheng Changjie Wu Chongrong Cao Guangwei | 2021 | Earthquake Engineering and Engineering Vibration2021，20，2： | 3 |
| 5 | In situ stress state and seismic hazard in the Dayi seismic gap of the Longmenshan thrust belt显示文摘In the Longmenshan thrust belt,the Dayi seismic gap,an area with few earthquakes,is located between the ruptures of the 2008 Wenchuan Earthquake and the 2013 Lushan Earthquake,with a length of approximately 40–60 km.To date,however,the extent of the seismic hazard of the Dayi seismic gap and whether this gap is under high stress are still hotly debated.To further evaluate the seismic hazard of the Dayi seismic gap with regard to stress,two boreholes(1,000 and 500 m deep)were arranged to carry out hydraulic fracturing in situ stress measurement on either side of the Shuangshi-Dachuan fault zone.This zone has a high seismic hazard and the capacity to undergo surface rupture.Through the analogy of this new data with stability analysis using Byerlee’s Law and existing stress measurement data collected before strong earthquakes,the results show that the area surrounding the Shuangshi-Dachuan fault zone in the Dayi seismic gap(Dachuan Town)is in a state of high in situ stress,and has the conditions necessary for friction slip,with the potential hazard of moderate to strong earthquakes.Our results are the first to reveal the in situ stress profile at a depth of 1,000 m in the Dayi seismic gap,and provide new data for comprehensive evaluation of the seismic hazard in this seismic gap,which is of great significance to explore the mechanism of earthquake occurrence and to help mitigate future disaster. | Bing LI Furen XIE Jinshui HUANG Xiwei XU Qiliang GUO Guangwei ZHANG Junshan XU Jianxin WANG Dawei JIANG Jian WANG Lifeng DING | 2022 | Science China Earth Sciences2022，65，7： | 3 |
| 6 | Persistence of Cry1Ac Protein from Transgenic Bt Cotton Cultivation and Residue Returning in Fields and Its Effect on Functional Diversity of Soil Microbial Communities显示文摘The persistence of Cry1 Ac protein in the soil and its effect on soil microbial communities are a core issue in assessing the ecological risk of transgenic Bacillus thuringiensis(Bt) cotton. In this study a field experiment was conducted on the cultivation of transgenic Bt cotton(Jin 26 and BtJ i 668) with the immediate returning of residues to the fields, in order to quantify the Cry1 Ac protein content in the fields and investigate its effects on the functional diversity of soil microbial communities. Cry1 Ac protein in the residue-soil mixture was gradually degraded in the transgenic Bt cotton fields. After transgenic Bt cotton straw was returned to the fields for 30 d, 63.73%and 58.33% of the initial amounts of Cry1 Ac protein were degraded in the Jin 26 and BtJ i 668 fields, respectively. Before the crops were sown in the following year(180 d after returning the straw), no Cry1 Ac protein was detected in the fields. After returning the cotton straw to the fields for 30 d, the Shannon-Wiener and McIntosh indices of soil microbial communities in the transgenic Bt cotton fields were significantly higher than those in the non-transgenic cotton fields. Meanwhile, the utilization of carbon sources including amino acids, amines, and carbohydrates by the soil microbial communities significantly increased. Both the McIntosh index and the utilization of carbohydrates increased until 180 d. Principal component analysis revealed that amino acids, amides, and carbohydrates were the main carbon sources distinguishing the two principal component factors. These findings indicated that Cry1 Ac protein did not accumulate in the fields after transgenic Bt cotton was planted for one year and the residues were immediately returned to the fields; however, the original functional diversity of soil microbial communities was affected continuously. | ZHANG Meijun FENG Meichen XIAO Lujie SONG Xiaoyan Guangwei DING YANG Wude | 2019 | Pedosphere2019，29，1： | 2 |
| 7 | Differentiating the early impacts of topsoil removal and soil amendments on crop performance/productivity of corn and soybean in eroded farmland of Chinese Mollisols显示文摘 | Yueyu Sui Xiaobing Liu Jian Jin Shaoliang Zhang Xingyi Zhang Stephen J. Herbert Guangwei Ding | 2009 | Field Crops Research2009，，3： | 1 |
| 8 | Soil erosion control practices in Northeast China: A mini-review显示文摘 | Xiaobing Liu Shaoliang Zhang Xingyi Zhang Guangwei Ding R.M. Cruse | 2011 | Soil & Tillage Research2011，，： | 1 |
| 9 | Fully Printed High‑Performance n‑Type Metal Oxide Thin‑Film Transistors Utilizing Coffee‑Ring Effect显示文摘Metal oxide thin-films transistors(TFTs)produced from solution-based printing techniques can lead to large-area electronics with low cost.However,the performance of current printed devices is inferior to those from vacuum-based methods due to poor film uniformity induced by the“coffeering”effect.Here,we report a novel approach to print highperformance indium tin oxide(ITO)-based TFTs and logic inverters by taking advantage of such notorious effect.ITO has high electrical conductivity and is generally used as an electrode material.However,by reducing the film thickness down to nanometers scale,the carrier concentration of ITO can be effectively reduced to enable new applications as active channels in transistors.The ultrathin(~10-nm-thick)ITO film in the center of the coffee-ring worked as semiconducting channels,while the thick ITO ridges(>18-nm-thick)served as the contact electrodes.The fully inkjet-printed ITO TFTs exhibited a high saturation mobility of 34.9 cm2 V^(−1) s^(−1) and a low subthreshold swing of 105 mV dec^(−1).In addition,the devices exhibited excellent electrical stability under positive bias illumination stress(PBIS,ΔV_(th)=0.31 V)and negative bias illuminaiton stress(NBIS,ΔV_(th)=−0.29 V)after 10,000 s voltage bias tests.More remarkably,fully printed n-type metal–oxide–semiconductor(NMOS)inverter based on ITO TFTs exhibited an extremely high gain of 181 at a low-supply voltage of 3 V,promising for advanced electronics applications. | Kun Liang Dingwei Li Huihui Ren Momo Zhao Hong Wang Mengfan Ding Guangwei Xu Xiaolong Zhao Shibing Long Siyuan Zhu Pei Sheng Wenbin Li Xiao Lin Bowen Zhu | 2021 | Nano-Micro Letters2021，13，11： | 1 |
| 10 | A CAUSATIVE ANALYSIS ON THE CHANGED USE OF FARMLAND RESOURCES IN CHINA显示文摘This article expounds the causative factors to the change in the use of farmland resources in China from the three aspects: industrialization and urbanization: the mounting disparity of comparative advantages in land use and irregular social behaviors. It proposes some countermeasures | Ding Guangwei and Li Shishun(The Commission for Integrated Survey of Natural Resources under the CAS) | 1999 | Bulletin of the Chinese Academy of Sciences1999，13，2： | 0 |
| 11 | Breaking the responsivity-speed dilemma of a-GaO_(x) photodetector by alternating gate modulation显示文摘The gallium oxide(Ga_(2)O_(3))based photodetectors are usually confronted with the typical challenge of the responsivity-speed(RS)dilemma,namely high photocurrent induces a long decay time,as shown in Figure 1(a).The RS dilemma involves a trade-off issue,which is independent of photoelectric materials. | Zhongfang ZHANG Pengju TAN Xiaohu HOU Xiaolan MA Mengfan DING Shunjie YU Guangwei XU Xiaolong ZHAO Shibing LONG | 2023 | Science China(Information Sciences)2023，66，12： | 0 |
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