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| 1 | Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography显示文摘Endoscopic retrograde cholangiopancrea tography(ERCP) is the most complex gastrointestinal procedure,which needs patients’ cooperation. The aim of this study was to observe the quality and safey of sedation with propofol in patients undergoing therapeutic ERCP. METHODS:Seventy patients who had undergone therapeutic ERCP were randomly divided into two groups.One group, given intravenously propofol, and the other sedated with routine method, served as the control. Blood pressure, heart rate,oxygen saturation were monitored and cardiorespiratory event was observed. Patient cooperation,performance, recovery time and amnesia served as variables postoperation. RESULTS:Blood pressure elevated in four patients in the propofol group, less than in the control group(P<0.01). Seven patients showed decreased blood pressure after administration of propofol,but none in the control group (P<0.01). Twelve patients in the control group showed mild or significant resistance, but none in the propofol group (P<0.01). The time for performance in the propofol group(P<0.05) was shorter than in the control group. Patient recovery was quicker in the propofol group than in the control group (P<0.01). The degree of amnesia better in the propofol group than in the control group ( P<0.01). The degree of amnesia was also better in the propofol group than in the control group (P<0.01). CONCLUSIONS:Propofol proves to be an excellent sedative for therapeutic ERCP. Being effective and safe, it shows a shorter ERCP duration but quick recovery and better amnesia. It is better than other routine sedatives. | Digestive Department (Chen WX, Lin HJ, Gu Q, Zhong XQ, Yu CH, Li YM and Gu ZY) and Department of Intensive Care Unit (Zhang WF), First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003 , China | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 10 |
| 2 | Association of nonalcoholic fatty liver disease with type 2 diabetes: clinical features and independent risk factors in diabetic fatty liver patients显示文摘Nonalcoholic fatty liver disease(NAFLD) is a common chronic liver disease in China, of which diabetic fatty liver (DFL) accounts for a large proportion in clinic. DFL is a disease without specific clinical features and lacking of confirmatory laboratory tests, and the etiology of hepatic steatosis remains poorly understood. The aim of this paper was to explore the clinical characteristics and to determine associated risk factors in type 2 diabetes patients with fatty liver. METHODS: A total of 166 patients, 53 in DFL group and 113 in NDFL(diabetes without fatty liver) group participated in this study. Serum fasting blood glucose (FBG), alanine aminotransferase(ALT), aspartate aminotransferase (AST), alkaline phosphate (AKP), gamma glutamyl transpeptidase (GGT), total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C) were measured in both groups. And these variables were analyzed by using Student’ s t test and logistic regression model. RESULTS:A progressive increase in the level of FBG, ALT, AST, AKP, GGT, TG( P<0.05) and a decrease of HDL-C(P<0.01)were observed from DFL group to NDFL group. And there was no statistical difference in the level of TC between the two groups. CONCLUSIONS:Dyslipidemia, dysglycemia and elevation of liver enzyme can be seen more frequently in the DFL patients than in the NDFL patients. The successive escalation of serum ALT and TG levels and the lower HDL-C level are the independent risk factors of DFL. | Department of Digestive Medicine, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China (Jin HB, Gu ZY, Yu CH and Li YM) | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 9 |
| 3 | Arsenic trioxide induces autophagic cell death in malignant glioma cells by unregulation or mitochondrial cell deaty protein BNIP3显示文摘 | Yan CH Liang ZQ Gu ZL etal | 2005 | Oncogene2005，24，6： | 1 |
| 4 | Contributions of autophagic and apoptotic mechanisms to CrTX-induced death of K562 cells显示文摘 | Yan CH Liang ZQ Gu ZL | 2006 | Toxicon2006，47，5： | 1 |
| 5 | Binding studies of paeonolum with bovine serum albumin using spectroscopic methods 显示文摘 | Chen Ch Y Gu X T Zhou Jiahong | 2007 | Spectroscopy2007，21，： | 1 |
| 6 | An overheight vehiclebridge collision monitoring system using piezoelectric transducers显示文摘 | Song G Ch Olmi C Gu H | 2007 | Smart Materials and Structures2007，16，2： | 1 |
| 7 | Progressive collapse of a two-story reinforced concrete frame with embedded smart aggregates显示文摘 | Laskar A Gu H Ch Mo Y L | 2009 | Smart Materials and Structures2009，18，07： | 1 |
| 8 | Effects of insulin therapy on inflammatory mediators in infants undergoing cardiac surgery with cardiopulmmary bypass 显示文摘 | Gu CH Gui Q Wang YY | 2006 | Cytokine2006，44，1： | 1 |
| 9 | Traffic networks in the Yangtze river delta metropolis circle显示文摘 | Gu CH G Pan S J J iang Y M | 2007 | The International Journal on Dynamics of Continuous Discrete Impulsive Systems2007，14，7： | 1 |
| 10 | Effects of sodium tanshinone IIA sulfonate against Marek's disease virus in experimentally infected chickens 显示文摘 | Zhang JQ Gu YL Wu CH | 2013 | International Journal of Biological Macro molecules2013，58，： | 1 |
| 11 | CT, MR, 18 F-FDG PET/CT, and their combined use for the assessment of mandibular invasion by squamous cell carcinomas of the oral cavity 显示文摘 | Gu DH Yoon DY Park CH | 2010 | Acta Radiol2010，14，10： | 1 |
| 12 | Performance of thallium-201 electrocardiography-gate myocardial perfusion single photon emission computed tomography to assess left ventricular function显示文摘 | Hung GU Hsia CH Yang PT | 2005 | Kaohsiung J Med Sci2005，21，5： | 1 |
| 13 | Nondestructive test and prediction of modulus of elasticity of veneer-overlaid particleboard composites 显示文摘 | HU Y CH WANG F H GU J Y | 2005 | Wood Science and Technology2005，39，6： | 1 |
| 14 | Insulin stimulates ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori显示文摘 | Gu SH Lin JL Lin PL Chen CH | 2009 | Insect Biochemistry Molecular Biology2009，39，3： | 1 |
| 15 | Chin J Chem显示文摘 | Li Q R Gu Ch Zh Yin H | 2006 | 24(1) : 72-782006，24，1： | 1 |
| 16 | GPU-based ultra fast dose calculation using a finite pencil beam model显示文摘 | Gu XJ Choi DJ Men CH | | 0，，20： | 1 |
| 17 | Overcoming multidrug resistance in 2D and 3D culture models by controlled drug chitosan-graft poly(caprolactone)-based nanoparticles显示文摘 | Shi WB Le VM Gu CH | 2014 | J Pharm Sci2014，103，4： | 1 |
| 18 | Myocardial apoptosis and infarction after ischemia/reperfusion are attenuated by κ-opioid receptor agonist显示文摘 | Rong F Peng Z Ye MX Zhang QY Zhao Y Zhang SM Guo HT Hui B Wang YM Liang C Gu CH Tao C Cui Q Yu SQ Yi DH Pei JM | 2009 | Arch Med Res2009，40，4： | 1 |
| 19 | How to determine the uptake of hydrogen accurately in carbonaceous materials 显示文摘 | Zhang Ch Lu X Sh Gu A Zh | 2004 | International Journal of Hydrogen Energy2004，29，12： | 1 |
| 20 | Recentness biased learn- ing for time series forecasting显示文摘 | GU S CH TAN Y HE X G | 2013 | Information Sciences2013，237，： | 1 |
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