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| 1 | Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries显示文摘冠的动脉把血流动带到心肌肉。理解冠的动脉的发展程序提供卓见进冠的动脉疾病的治疗。多重来源被描述了为包括 proepicardium,湾穴 venosus (SV ) ,和心内膜贡献冠的动脉。然而,冠的容器的发展起源仍然在强烈学习下面。我们为学习冠的开发生产了一个新基因工具,一只 AplnCreER 老鼠在开发冠的容器明确地衬里 recombinase,它表示可诱导的 Cre。冠的开发和 AplnCreER 命运跟踪的预定正式就职的定量分析证明 subepicardial endothelial 房间(EC ) 的子孙两个都入侵紧缩的心肌层形成冠的动脉并且在表面上留下生产静脉。我们发现这些 subepicardial EC 是 intramyocardial 的主要来源在发展中的心的冠的容器。在 vitro 将生物的活组织移植于培养基中培养,试金显示这些 subepicardial EC 的多数从 SV 和中庭的心内膜,然而并非从室的心内膜产生。Apln 积极的房间的同种细胞的分析显示单个 subepicardial EC 同等地作出贡献到冠的动脉和静脉。一起,这些数据建议 subepicardial EC 是 intramyocardial 的主要来源在室的冠的动脉墙,和那冠的动脉和静脉在发展中的心有普通起源。 | Xueying Tian Tianyuan Hu Hui Zhang Lingjuan He Xiuzhen Huang Qiaozhen Liu Wei Yu Liang He Zhongzhou Yang Zhen Zhang Tao P Zhong Xiao Yang Zhen Yang Yan Yan Antonio Baldini Yunfu Sun Jie Lu Robert J Schwartz Sylvia M Evans Adriana C Gittenberger-de Groot Kristy Red-Horse Bin Zhou | 2013 | Cell Research2013，23，9： | 3 |
| 2 | Demonstration of controlled-not quantum gates on a pair of superconducting quantum bits显示文摘 | Plantenberg J H Groot P C Mooij J E | 2007 | Nature2007，447，7146： | 1 |
| 3 | Coagulation disorders in septic shock 显示文摘 | Thijs L G de Boer J P de Groot M C | 1993 | Intensive Care Med1993，19，1： | 1 |
| 4 | Proteomlc analysis of Arabidopsis seed germination and priming 显示文摘 | Gallardo K Job C Groot S P C | 2001 | Plant Physiol2001，126，： | 1 |
| 5 | Effects of water stress on photosynthesis and chlorophyll fluorescence of five potato cultivars显示文摘 | SCHAPENDONK AHCM SPRITTERS C J T GROOT P J | 1989 | Potato Res1989，32，： | 1 |
| 6 | Studies of solubility of different calcium phosphate ceramic particles in vitro显示文摘 | Klein C P A T Wolke J G C Groot K | 1990 | Biomaterials1990，11，4： | 1 |
| 7 | Signal modeling for low-coherence height-scanning interference microsopy显示文摘 | de Groot P de Lega X C | 2004 | Appl Opt2004，43，： | 1 |
| 8 | Characterisation of peripartum cardiomyopathy by cardiac magnetic resonance imaging 显示文摘 | MOUQUET F LIONS C DE GROOTE P | 2008 | igur Radiol2008，18，12： | 1 |
| 9 | Proteomic analysis of Arabidopsis seed germination and priming显示文摘 | Gallardo K Job C Groot S P C | 2001 | Plant Physiol2001，126，： | 1 |
| 10 | Proteomic analysis of Arabidopsis seed germination and priming显示文摘 | Gallardo K Job C Groot S P C | | 0，，126： | 1 |
| 11 | Comparison of oxygen isotope records from the GISP2 and GRIP Greenland ice cores显示文摘 | Grootes P M Stuiver M White J W C | 1993 | Nature1993，366，： | 1 |
| 12 | Comparison of oxygen isotope records from the GISP2 and GRIP Greenland ice cores 显示文摘 | Grootes P M Stulver M White J W C | 1993 | Nature1993，366，55： | 1 |
| 13 | Right ventricular ejection fraction is an independent predictor of survival in patients with moderate heart failure显示文摘 | de Groote P Millaire A Foucher-Hossein C | 1998 | J Am Coll Cardiol1998，32，： | 1 |
| 14 | Randomized trial of cyclophosphamide versus methotrexate for induction of remission in early systemic antineutrophil cytoplasmic antibody associated vasculitis 显示文摘 | De Groot K Rasmussen N Bacon P A Tervaert J W Feighery C Gregorini G | 2005 | Arthritis Rheum2005，52，： | 1 |
| 15 | East Asian monsoon climate during the Late Pleistocene:high resolution sediment records from the South China Sea显示文摘 | Wang L Sarnthein M Erlenkeuser H Grimalt J Grootes P Heilig S Ivanova E Kienast M Pelejero C Pflaumann U | 1999 | Marine Geology1999，156，： | 1 |
| 16 | Proteome-wide characterization of seed ageing in arabidopsis:a comparison between artificial and natural aging protocols显示文摘 | Rajjou L Lovigny Y Groot S P C | 2008 | Plant Physiology2008，148，1： | 1 |
| 17 | Fatty acid activation : specificity, localization, and function 显示文摘 | Groot P H Schohe H R Hulsmann W C | 1976 | Advances in lipid research1976，14，： | 1 |
| 18 | Re-lationships with activation markers of T cells,Bcells,and monocytes显示文摘 | Descamps-Latscha B Herbelin A Nguyen AT Roux-Lombard P Zingraff J Moynot A Verger C DahmaneD De Groote D Jungers P:Balance between IL-1 be-ta TNF-alpha and their specific inhibitors inchronic renal failure and maintenance dialysis | 1995 | J Immunol1995，，： | 1 |
| 19 | Proteomic analysis of Arabidopsis seed germination and priming显示文摘 | Gallardo K Job C Groot S P | 2001 | Plant Physiology2001，126，2： | 1 |
| 20 | Fatigue Behavior of Calcium Phosphate Coatings with Different Stability under Dry and Wet Conditions显示文摘 | Clemens J A Wolke J G Klein C P de Groot K | 1999 | J Biomed Mater Res1999，48，： | 1 |
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