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| 1 | 诊断性试验和策略的证据质量和推荐强度的分级显示文摘GRADE系统能对诊断性试验或策略的证据质量和推荐强度进行分级。本文旨在阐释在此过程中如何考虑患者的重要结局, | Holger J Schünemann Andrew D Oxman Jan Brozek Paul Glasziou Roman Jaeschke Gunn E Vist John W Williams Jr Regina Kunz Jonathan Craig Victor M Montori Patrick Bossuyt Gordon H Guyatt 李晓 黄程 陈耀龙 李幼平 | 2009 | 中国循证医学杂志2009，9，5： | 7 |
| 2 | Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation显示文摘BACKGROUND The impact of perioperative blood transfusion on short-and long-term outcomes in pediatric living donor liver transplantation(PLDLT)must still be ascertained,mainly among young children.Clinical and surgical postoperative complications related to perioperative blood transfusion are well described up to three months after adult liver transplantation.AIM To determine whether transfusion is associated with early and late postoperative complications and mortality in small patients undergoing PLDLT.METHODS We evaluated the effects of perioperative transfusion on postoperative complications in recipients up to 20 kg of body weight,submitted to PLDLT.A total of 240 patients were retrospectively allocated into two groups according to postoperative complications:Minor complications(n=109)and major complications(n=131).Multiple logistic regression analysis identified the volume of perioperative packed red blood cells(RBC)transfusion as the only independent risk factor for major postoperative complications.The receiver operating characteristic curve was drawn to identify the optimal volume of the perioperative RBC transfusion related to the presence of major postoperative complications,defining a cutoff point of 27.5 mL/kg.Subsequently,patients were reallocated to a low-volume transfusion group(LTr;n=103,RBC≤27.5 mL/kg)and a high-volume transfusion group(HTr;n=137,RBC>27.5 mL/kg)so that the outcome could be analyzed.RESULTS High-volume transfusion was associated with an increased number of major complications and mortality during hospitalization up to a 10-year follow-up period.During a short-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and bleeding complications,with a decrease in rejection complications compared to the LTr.Over a long-term period,the HTr showed an increase in major infectious,cardiovascular,respiratory,and minor neoplastic complications,with a decrease in rejection complications.Additionally,Cox hazard regression found that high-volume RBC transfusion increased the mortality risk by 3.031-fold compared to low-volume transfusion.The Kaplan-Meier survival curves of the studied groups were compared using log-rank tests and the analysis showed significantly decreased graft survival,but with no impact in patient survival related to major complications.On the other hand,there was a significant decrease in both graft and patient survival,with high-volume RBC transfusion.CONCLUSION Transfusion of RBC volume higher than 27.5 mL/kg during the perioperative period is associated with a significant increase in short-and long-term postoperative morbidity and mortality after PLDLT. | Karina Gordon Estela Regina Ramos Figueira Joel Avancini Rocha-Filho Luiz Antonio Mondadori Eduardo Henrique Giroud Joaquim Joao Seda-Neto Eduardo Antunes da Fonseca Renata Pereira Sustovitch Pugliese Agustin Moscoso Vintimilla Jose Otavio Costa Auler Jr Maria Jose Carvalho Carmona Luiz Augusto Carneiro D'Alburquerque | 2021 | World Journal of Gastroenterology2021，27，12： | 6 |
| 3 | Incidence of Important Hemobilia Following Transhepatic Biliary Drainage: Left-Sided Versus Right-Sided Approaches显示文摘 | G. M. Rivera-Sanfeliz O. S. A. Assar J. M. LaBerge M. W. Wilson R. L. Gordon E. J. Ring R. K. Kerlan Jr | 2004 | CardioVascular and Interventional Radiology2004，，： | 2 |
| 4 | Mast cell as a source of both performed and immunologically inducible TNFα/cachectin 显示文摘 | Gordon JR Galli SJ | 1990 | Nature1990，346，： | 1 |
| 5 | Mast cells as a source of multifunctional cytokines显示文摘 | Gordon JR Burd PR Galli SJ | 1990 | Immunol Today1990，11，： | 1 |
| 6 | The meas- urement of urinary oxalic acid by derivatization coupled with liquid chromatography 显示文摘 | Murray JF Jr Nolen HW 3rd Gordon GR | 1982 | Anal Biochem1982，121，2： | 1 |
| 7 | Increased insulin-like growth factor-1 gene expression precedes left ventricular cardiomyocyte hypertrophy in a rapidly-hypertrophying rat model system 显示文摘 | Huang CY Buchanan DL Gordon RL Jr | 2003 | Cell Biochem Funct2003，21，4： | 1 |
| 8 | Synergistic enhancement of antitumor immunity with adoptively transferred tumor-specific CD4^+ and CD8^+ T cells and intratumoral lymphotacin transgene expression显示文摘 | Huang H Li F Gordon JR | 2002 | Cancer Res2002，62，7： | 1 |
| 9 | A microscopic study of organic particles in the North Atlantic Ocean显示文摘 | GORDON Jr D C | 1970 | Deep Sea Research1970，17，1： | 1 |
| 10 | CXCL8((3-73显示文摘 | Li F Zhang X Gordon JR | | 0，，03： | 1 |
| 11 | Regulatory dendritic cells for immunotherapy in immunologic diseases显示文摘 | Gordon JR Ma Y Churchman L | 2014 | Front Immunol2014，5，： | 1 |
| 12 | QIIME allows analysis of high-throughput community sequencing data 显示文摘 | Caporaso JG Kuczynski J Stombaugh J Bittinger K Bushman FD Costello EK Fierer N Pena AG Goodrich JK Gordon JI Huttley GA Kelley ST Knights D Koenig JE Ley RE Lozupone CA Mcdonald D Muegge BD Pirrung M Reeder J Sevinsky JR Tumbaugh PJ Walters WA Widmann J Yatsunenko T Zaneveld J Knight R | 2010 | Nat Methods2010，7，5： | 1 |
| 13 | Increased Synthesis of extracellular matrix in mesangial proliferative nephritis显示文摘 | Floege JR Johnson J Gordon K | 1991 | Kid Int1991，40，： | 1 |
| 14 | Dopaminergic dysregulation in mice selectively bred for excessive exercise or obesity显示文摘 | Mathes WF Nehrenberg DL Gordon R Hua K Garland T Jr Pomp D | 2010 | Behav Brain Res2010，210，2： | 1 |
| 15 | The functional signifi-cance behind expressing two IL-8 receptor types on PMN显示文摘 | Stillie R Farooq SM Gordon JR | 2009 | JLeukoc Biol2009，86，3： | 1 |
| 16 | Delayed laparos- copy facilitates the management of biliary peritonitis in patients with complex liver injuries 显示文摘 | Carrillo EH Reed DN Jr Gordon L | 2001 | Surg Endose2001，15，： | 1 |
| 17 | Opposing effects of short-and longterm stress on airway inflammation 显示文摘 | Forsythe P Ebeling C Gordon JR | 2004 | Am J Resp Crit Care Med2004，169，2： | 1 |
| 18 | A simplified technique for revasuscularization of homografts of the liver with a variant right hepatic artery from the superior mesenteric artery显示文摘 | Gordon RD Shaw BW Jr Iwatsuki S | 1985 | Surg Gynecol Obstet1985，160，5： | 1 |
| 19 | Mast cells as a source of multifuncitional cytokines显示文摘 | Gordon JR Burd PR Galli SJ | 1990 | Immunol Today1990，11，： | 1 |
| 20 | The role of the gastrointestinal system in ' idiopathic hypoproteinemia' 显示文摘 | Waldmann TA Steinfeld JL Dutcher TF Davidson JD Gordon RS Jr | 1961 | Gastroenterology1961，41，： | 1 |
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