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| 1 | 美国教育博士学位的背景与发展显示文摘本文简要记载美国基础教育在改革大环境中对领导管理人员专业培训的需要,以皮博迪学院教育博士学位的定位框架和规格标准为例,在治学宗旨、办学对象、教学方式等方面综述当前美国学术界对教育博士的定位和改良的探讨,为中国高校探索教育领导管理专业学位的设置和发展提供参考。 | 陈粤秀 Ellen Goldring Catherine Loss | 2009 | 复旦教育论坛2009，7，3： | 5 |
| 2 | Tetracycline-inducible protein expression in pancreatic cancer cells: Effects of CapG overexpression显示文摘AIM: To establish stable tetracycline-inducible pancreatic cancer cell lines. METHODS: Suit-2, MiaPaca-2, and Panc-1 cells were transfected with a second generation reverse tetracycline-controlled transactivator protein (rtTA2S-M2), under the control of either a cytomegalovirus (CMV) or a chicken β-actin promoter, and the resulting clones were characterised.RESULTS: Use of the chicken (β-actin) promoter proved superior for both the production and maintenance of doxycycline-inducible cell lines. The system proved versatile, enabling transient inducible expression of a variety of genes, including GST-P, CYP2E1, S100A6, and the actin capping protein, CapG. To determine the physiological utility of this system in pancreatic cancer cells, stable inducible CapG expressors were established. Overexpressed CapG was localised to the cytoplasm and the nuclear membrane, but was not observed in the nucleus. High CapG levels were associated with enhanced motility, but not with changes to the cell cycle, or cellular proliferation. In CapG-overexpressing cells, the levels and phosphorylation status of other actin-moduating proteins (Cofilin and Ezrin/Radixin) were not altered. However, preliminary analyses suggest that the levels of other cellular proteins, such as ornithine aminotransferase and enolase, are altered upon CapG induction. CONCLUSION: We have generated pancreatic-cancer derived cell lines in which gene expression is fully controllable. | Sarah Tonack Sabina Patel Mehdi Jalali Taoufik Nedjadi Rosalind E Jenkins Christopher Goldring John Neoptolemos Eithne Costello | 2011 | World Journal of Gastroenterology2011，17，15： | 4 |
| 3 | Anti-inflammatory activity of an ethanolic Caesalpinia sappan extract in human chondrocytes and macrophages显示文摘 | Shengqian Q. Wu Miguel Otero Frank M. Unger Mary B. Goldring Ampai Phrutivorapongkul Catharina Chiari Alexander Kolb Helmut Viernstein Stefan Toegel | 2011 | Journal of Ethnopharmacology2011，，2： | 3 |
| 4 | The regulation of chondrocyte function by proinflammatorymediators:prostaglandnis and nitric oxide显示文摘 | Berenbaum Francis M D | 2004 | Clini Orthop Relat Res2004，1，427： | 1 |
| 5 | The role of cytokines as inflammatory mediators in osteoarthritis:lessons from animal models显示文摘 | Goldring MB | 1999 | Connect Tissue Res1999，40，1： | 1 |
| 6 | Extract of Ginkgo biloba induces phase 2 genes through Keapl-Nrf2-ARE signaling pathway显示文摘 | LIU XP GOLDRING CE COPPLE IM | 2007 | Life Sci2007，80，17： | 1 |
| 7 | Cellular mechanisms and the role of cytokines in bone erosions in rheumatoid arthritis显示文摘 | Gravallese EM Goldring SR | 2000 | Arthritis Rheum2000，43，10： | 1 |
| 8 | Cartilage homeostasis in health and rheum aticd iseases显示文摘 | Goldring M B Marcu K B | 2009 | Arthritis Res Ther2009，11，3： | 1 |
| 9 | The role of the chondrocyte in osteoarthritis显示文摘 | Goldring MB | 2000 | Arthritis Rheum2000，43，9： | 1 |
| 10 | The role of synovitis in osteoarthritis pathogenesis显示文摘 | Scanzello CR Goldring SR | 2012 | Bone2012，51，2： | 1 |
| 11 | Cellular mechanism and the role ofcytokines in bone erosions in rheumatoid arthritis显示文摘 | Gravallese EM Goldring SR | 2000 | Arthritis Rheum2000，43，10： | 1 |
| 12 | RoLes of inflammatory and anabolic cytokines in cartilage metabolism: signals and multi- ple effectors converge upon MMP-13 regulation in osteoarthritis 显示文摘 | Goldring MB Otero M Plumb DA | 2011 | Eur Cell Mater2011，21，： | 1 |
| 13 | The effect of radiofrequency current and heat on peripheral nerve action potential in the cat显示文摘 | LETCHER F S GOLDRING S | 1968 | J Neurosurg1968，29，1： | 1 |
| 14 | The synovial-like membrane at the bone-cement interface in loosen total hip replacements and its proposed role in bone lysis显示文摘 | Goldring SR Schiller AL Roelke M | 1983 | J Bone Joint Surg1983，65，： | 1 |
| 15 | WISP3-dependent regulation of type 11 collagen and aggrecan production in chondrocytes显示文摘 | Sen M Cheng Y H Goldring M B | 2004 | Arthritis Rheum2004，50，2： | 1 |
| 16 | Pathogenesis of bone erosions in rheumatoid arthritis 显示文摘 | Goldring SR Gravallese EM | 2000 | Curr Opin Rheumatol2000，12，： | 1 |
| 17 | The regulation of chondrocyte function by proinflammatory mediators:Prostaglandins and nitric oxide显示文摘 | Goldring MB Berenbaum F | 2004 | Clin Orthop Relat Res2004，，427： | 1 |
| 18 | The control of chondrogenesis显示文摘 | Goldring Mb Tsuchimochi Kljiri k | | 0，，1： | 1 |
| 19 | Novel phomactin analogues as PAF receptor ligands 显示文摘 | GOLDRING W P D ALEXANDER S P H KENDAI I D A | 2005 | Bioorg Med Chem Lett2005，15，13： | 1 |
| 20 | The synovial-like membrane at the bone cement interface in loose total hip replacement and its proposed role in bone lysis显示文摘 | Schiller AL Roelke M | 1993 | J Bone Joint Surg(Am)1993，65，： | 1 |
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