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| 1 | Costs of laparoscopic and open liver and pancreatic resection:A systematic review显示文摘AIM:To study costs of laparoscopic and open liver and pancreatic resections,all the compiled data from available observational studies were systematically reviewed.METHODS:A systematic review of the literature was performed using the Medline,Embase,Pub Med,and Cochrane databases to identify all studies published up to 2013 that compared laparoscopic and open liver[laparoscopic hepatic resection(LLR)vs open liver resection(OLR)]and pancreatic[laparoscopic pancreatic resection(LPR)vs open pancreatic resection]resection.The last search was conducted on October 30,2013.RESULTS:Four studies reported that LLR was associated with lower ward stay cost than OLR(2972 USD vs 5291 USD).The costs related to equipment(3345USD vs 2207 USD)and theatre(14538 vs 11406)were reported higher for LLR.The total cost was lower in patients managed by LLR(19269 USD)compared to OLR(23419 USD).Four studies reported that LPR was associated with lower ward stay cost than OLR(6755vs 9826 USD).The costs related to equipment(2496USD vs 1630 USD)and theatre(5563 vs 4444)were reported higher for LPR.The total cost was lower in the LPR(8825 USD)compared to OLR(13380 USD).CONCLUSION:This systematic review support the economic advantage of laparoscopic over open approach to liver and pancreatic resection. | Paolo Limongelli Chiara Vitiello Andrea Belli Madhava Pai Salvatore Tolone Gianmattia del Genio Luigi Brusciano Giovanni Docimo Nagy Habib Giulio Belli Long Richard Jiao Ludovico Docimo | 2014 | World Journal of Gastroenterology2014，20，46： | 5 |
| 2 | 克氏综合征患者的睾丸实质异常:一个有关肿瘤的问题?40例连续患者的研究显示文摘克氏综合征(Ks)是一种以染色体核型47,XXY为特征的高促性腺激素性腺功能减退症。一般而言,KS患者患睾丸肿瘤的风险与睾丸肿瘤的病因学理论是相关的;尽管其风险似乎是低下的。我们评估了对KS患者通过影像学检查以及血清肿瘤标记物检测进行睾丸肿瘤筛查的必要性。从2009年12月至2013年1月,共有40名KS患者参与了此项研究。在研究开始阶段、6个月以及随后每年对患者的血清乳酸脱氢酶(LDHl,甲胎蛋白(AFP)以及人绒毛膜促性腺激素B亚单位(beta-hCG)水平进行测定,并行睾丸彩色多普勒超声检查。当睾丸超声提示微钙化、睾丸结节以及囊肿时行腹部磁共振检查。62%的患者有规则的睾丸回声,37.5%出现不规则回声,17.5%有微钙化和囊肿。87%出现规则的血管结构,12.5%有精索静脉曲张,12.5%的患者结节〈1cm,但无患者结节大于1cm。磁共振检查排除了所有伴睾丸微钙化、结节和囊肿的患者忠睾丸肿瘤的可能性。随访未发现乳酸脱氢酶、甲胎蛋白、人绒毛膜促性腺激素B亚单位水平以及超声特征的显著改变。我们比较了有隐睾和无隐睾的克氏综合症患者血清肿瘤标记物水平以及其超声特征,发现并无统计学差异。研究未在KS患者中发现睾丸肿瘤,同时,在选定的患者中,睾丸超声、肿瘤标记物以及磁共振并不是鉴别良恶性病变的有效手段。 | Giacomo Accardo Gianfranco Vallone Daniela Esposito Filomena Barbato Andrea Renzullo Giovanni Conzo Giovanni Docimo Katherine Esposito Daniela Pasquali | 2015 | Asian Journal of Andrology2015，17，1： | 2 |
| 3 | Recent trends in endoscopic management of achalasia显示文摘Esophageal achalasia is a chronic and progressive motility disorder characterized by absence of esophageal body peristalsis associated with an impaired relaxation of lower esophageal sphincter(LES) and usually with an elevated LES pressure, leading to an altered passage of bolus through the esophago-gastric junction. A definitive cure for achalasia is currently unavailable. Palliative treatment options provide only food and liquid bolus intake and relief of symptoms. Endoscopic therapy for achalasia aims to disrupt or weaken the lower esophageal sphincter. Intra-sphincteric injection of botulinum toxin is reserved for elderly or severely ill patients. Pneumatic dilation provides superior results than botulinum toxin injection and a similar mediumterm efficacy almost comparable to that attained after surgery. Per oral endoscopic myotomy is a promising option for treating achalasia, but it requires increased experience and further objective and long-term follow up. This article will review different endoscopic treatments in achalasia, and summarize the short-term and long-term outcomes. | Salvatore Tolone Paolo Limongelli Gianmattia del Genio Luigi Brusciano Antonio Russo Lorenzo Cipriano Marco Terribile Giovanni Docimo Roberto Ruggiero Ludovico Docimo | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，9： | 1 |
| 4 | Total thyroidectomy, without prophylactic central lymph node dissection, in the treatment of differentiated thyroid cancer. Clinical retrospective study on 221 cases显示文摘 | Giovanni Conzo Daniela Pasquali Giuseppe Bellastella Katherine Esposito Carlo Carella Annamaria Bellis Giovanni Docimo Michele Klain Sergio Iorio Salvatore Napolitano Antonietta Palazzo Alessandra Pizza Antonio Agostino Sinisi Emilia Zampella Antonio Bell | 2013 | Endocrine2013，，2： | 1 |
| 5 | Esophageal papilloma: Flexible endoscopic ablation by radiofrequency显示文摘Squamous papilloma of the esophagus is a rare benign lesion of the esophagus. Radiofrequency ablation is an established endoscopic technique for the eradication of Barrett esophagus. No cases of endoscopic ablation of esophageal papilloma by radiofrequency ablation(RFA) have been reported. We report a case of esophageal papilloma successfully treated with a single session of radiofrequency ablation. Endoscopic ablation of the lesion was achieved by radiofrequency using a new catheter inserted through the working channel of endoscope. The esophageal ablated tissue was removed by a specifically designed cup. Complete ablation was confirmed at 3 mo by endoscopy with biopsies. This case supports feasibility and safety of as a new potential indication for BarrxTM RFA in patients with esophageal papilloma. | Gianmattia del Genio Federica del Genio Pietro Schettino Paolo Limongelli Salvatore Tolone Luigi Brusciano Manuela Avellino Chiara Vitiello Giovanni Docimo Angelo Pezzullo Ludovico Docimo | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，3： | 0 |
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