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| 1 | Role of Arabidopsis UV RESISTANCE LOCUS 8 in Plant Growth Reduction under Osmotic Stress and Low Levels of UV-B显示文摘在热点环境,植物暴露于压力的不同类型,例如触发普通 morphogenic 的 UV-B,而且 droughtstress 的过量适应反应导致植物生长的一般减小。这里,我们 reportthat Arabidopsis thaliana 紫外抵抗地点 8 (UVR8 ) 基因, UV-B morphogenic 反应的一个已知的管理者,能补充 Saccharomyces cerevisiae osmo 敏感的异种和它的表示在 Arabidopsis 植物在渗透或咸的应力以后被导致。在 UV-B 的底层下面,植物 overexpressing UVR8 与减少的根开发被相形见绌并且与控制植物相比积累更多的 flavonoids。生长 defectsare 主要由于细胞扩大的抑制。UVR8 overexpression 在 UV-B 的底层下面在植物触发的生长抑制被导致甘露糖醇的渗透的应力加重,但是它不是由离子的应力的 significantlyaffected。相反, uvr8-6 异种植物不在标准条件下面不同于野类型的植物,但是他们显示出一个增加的射击生长 underhigh 盐压力。我们的数据建议 flavonoid 并且可能的调停 UVR8 的累积在植物生长素 homeostasisare 改变观察生长显型的内在的机制并且 UVR8 可能为 integratingplant 生长和压力 signals.Key 词有一个重要角色: | Rossella Fasano Nathalie Gonzalez Alessandra Tosco Fabrizio Dal Piaz Teresa Docimo Ramon Serrano Stefania Grillo Antonella Leone Dirk Inze | 2014 | Molecular Plant2014，7，5： | 7 |
| 2 | Costs of laparoscopic and open liver and pancreatic resection:A systematic review显示文摘AIM:To study costs of laparoscopic and open liver and pancreatic resections,all the compiled data from available observational studies were systematically reviewed.METHODS:A systematic review of the literature was performed using the Medline,Embase,Pub Med,and Cochrane databases to identify all studies published up to 2013 that compared laparoscopic and open liver[laparoscopic hepatic resection(LLR)vs open liver resection(OLR)]and pancreatic[laparoscopic pancreatic resection(LPR)vs open pancreatic resection]resection.The last search was conducted on October 30,2013.RESULTS:Four studies reported that LLR was associated with lower ward stay cost than OLR(2972 USD vs 5291 USD).The costs related to equipment(3345USD vs 2207 USD)and theatre(14538 vs 11406)were reported higher for LLR.The total cost was lower in patients managed by LLR(19269 USD)compared to OLR(23419 USD).Four studies reported that LPR was associated with lower ward stay cost than OLR(6755vs 9826 USD).The costs related to equipment(2496USD vs 1630 USD)and theatre(5563 vs 4444)were reported higher for LPR.The total cost was lower in the LPR(8825 USD)compared to OLR(13380 USD).CONCLUSION:This systematic review support the economic advantage of laparoscopic over open approach to liver and pancreatic resection. | Paolo Limongelli Chiara Vitiello Andrea Belli Madhava Pai Salvatore Tolone Gianmattia del Genio Luigi Brusciano Giovanni Docimo Nagy Habib Giulio Belli Long Richard Jiao Ludovico Docimo | 2014 | World Journal of Gastroenterology2014，20，46： | 5 |
| 3 | Pre-operative clinical and instrumental factors as antireflux surgery outcome predictors显示文摘Gastroesophageal reflux disease(GERD) is nowadays a highly prevalent, chronic condition, with 10% to 30% of Western populations affected by weekly symptoms. Many patients with mild reflux symptoms are treated adequately with lifestyle modifications, dietary changes, and low-dose proton pump inhibitors(PPIs). For those with refractory GERD poorly controlled with daily PPIs, numerous treatment options exist. Fundoplication is currently the most commonly performed antireflux operation for management of GERD. Outcomes described in current literature following laparoscopic fundoplication indicate that it is highly effective for treatment of GERD; early clinical studies demonstrate relief of symptoms in approximately 85%-90% of patients. However it is still unclear which factors, clinical or instrumental, are able to predict a good outcome after surgery. Virtually all demographic, esophagogastric junction anatomic conditions, as well as instrumental(such as presence of esophagitis at endoscopy, or motility patterns determined by esophageal high resolution manometry or reflux patterns determined by means of pH /impedance-pH monitoring) and clinical features(such as typical or atypical symptoms presence) of patients undergoing laparoscopic fundoplication for GERD can be factors associated with symptomatic relief. With this in mind, we sought to review studies that identified the factors that predict outcome after laparoscopic total fundoplication. | Salvatore Tolone Giorgia Gualtieri Edoardo Savarino Marzio Frazzoni Nicola de Bortoli Manuele Furnari Giuseppina Casalino Simona Parisi Vincenzo Savarino Ludovico Docimo | 2016 | World Journal of Gastrointestinal Surgery2016，8，11： | 3 |
| 4 | The “mini-perc” technique: a less invasive alternative to percutaneous nephrolithotomy显示文摘 | Stephen V. Jackman Steven G. Docimo Jeffrey A. Cadeddu Jay T. Bishoff Louis R. Kavoussi Thomas W. Jarrett | 1998 | World Journal of Urology1998，，6： | 2 |
| 5 | Transcriptome reprogramming,epigenetic modifications and alternative splicing orchestrate the tomato root response to the beneficial fungus Trichoderma harzianum显示文摘Beneficial interactions of rhizosphere microorganisms are widely exploited for plant biofertilization and mitigation of biotic and abiotic constraints.To provide new insights into the onset of the roots–beneficial microorganisms interplay,we characterised the transcriptomes expressed in tomato roots at 24,48 and 72 h post inoculation with the beneficial fungus Trichoderma harzianum T22 and analysed the epigenetic and post-trascriptional regulation mechanisms.We detected 1243 tomato transcripts that were differentially expressed between Trichoderma-interacting and control roots and 83 T.harzianum transcripts that were differentially expressed between the three experimental time points.Interaction with Trichoderma triggered a transcriptional response mainly ascribable to signal recognition and transduction,stress response,transcriptional regulation and transport.In tomato roots,salicylic acid,and not jasmonate,appears to have a prominent role in orchestrating the interplay with this beneficial strain.Differential regulation of many nutrient transporter genes indicated a strong effect on plant nutrition processes,which,together with the possible modifications in root architecture triggered by ethylene/indole-3-acetic acid signalling at 72 h post inoculation may concur to the well-described growth-promotion ability of this strain.Alongside,T.harzianum-induced defence priming and stress tolerance may be mediated by the induction of reactive oxygen species,detoxification and defence genes.A deeper insight into gene expression and regulation control provided first evidences for the involvement of cytosine methylation and alternative splicing mechanisms in the plant–Trichoderma interaction.A model is proposed that integrates the plant transcriptomic responses in the roots,where interaction between the plant and beneficial rhizosphere microorganisms occurs. | Monica De Palma Maria Salzano Clizia Villano Riccardo Aversano Matteo Lorito Michelina Ruocco Teresa Docimo Anna Lisa Piccinelli Nunzio D’Agostino Marina Tucci | 2019 | Horticulture Research2019，6，1： | 2 |
| 6 | 克氏综合征患者的睾丸实质异常:一个有关肿瘤的问题?40例连续患者的研究显示文摘克氏综合征(Ks)是一种以染色体核型47,XXY为特征的高促性腺激素性腺功能减退症。一般而言,KS患者患睾丸肿瘤的风险与睾丸肿瘤的病因学理论是相关的;尽管其风险似乎是低下的。我们评估了对KS患者通过影像学检查以及血清肿瘤标记物检测进行睾丸肿瘤筛查的必要性。从2009年12月至2013年1月,共有40名KS患者参与了此项研究。在研究开始阶段、6个月以及随后每年对患者的血清乳酸脱氢酶(LDHl,甲胎蛋白(AFP)以及人绒毛膜促性腺激素B亚单位(beta-hCG)水平进行测定,并行睾丸彩色多普勒超声检查。当睾丸超声提示微钙化、睾丸结节以及囊肿时行腹部磁共振检查。62%的患者有规则的睾丸回声,37.5%出现不规则回声,17.5%有微钙化和囊肿。87%出现规则的血管结构,12.5%有精索静脉曲张,12.5%的患者结节〈1cm,但无患者结节大于1cm。磁共振检查排除了所有伴睾丸微钙化、结节和囊肿的患者忠睾丸肿瘤的可能性。随访未发现乳酸脱氢酶、甲胎蛋白、人绒毛膜促性腺激素B亚单位水平以及超声特征的显著改变。我们比较了有隐睾和无隐睾的克氏综合症患者血清肿瘤标记物水平以及其超声特征,发现并无统计学差异。研究未在KS患者中发现睾丸肿瘤,同时,在选定的患者中,睾丸超声、肿瘤标记物以及磁共振并不是鉴别良恶性病变的有效手段。 | Giacomo Accardo Gianfranco Vallone Daniela Esposito Filomena Barbato Andrea Renzullo Giovanni Conzo Giovanni Docimo Katherine Esposito Daniela Pasquali | 2015 | Asian Journal of Andrology2015，17，1： | 2 |
| 7 | The mini - perc technique; a less invasive alternative to percutaneous nephrolithotomy显示文摘 | Jackman S V Docimo S G Cadeddu J A | 1998 | World J Uro11998，16，： | 1 |
| 8 | The resulfs of surgical therapy for cryptorchid- ism : a literature review and analysis 显示文摘 | Docimo SG | 1995 | J Urol1995，154，3： | 1 |
| 9 | The results of surgical therapy for cryptorchidism:aliterature review and analysis显示文摘 | | 1995 | J Urol1995，154，3： | 1 |
| 10 | The'minipete'technique:a less invasive alternative to percutaneous nephrolithotomy显示文摘 | Docimo SG Cadeddu JA | 1998 | World J Urol1998，16，3： | 1 |
| 11 | The 'mini-pere' technique: a less invasive alternative to percutaneous nephrolithotomy显示文摘 | Jackman S V Docimo S G Gadeddu J A | 1998 | World J Urol1998，16，： | 1 |
| 12 | The low scrotal approach to the ectopic or ascended testicle:prevalence of a patent processus vaginalis显示文摘 | Parsons JK Ferrer F Docimo SG | | 0，，： | 1 |
| 13 | The ULL technique显示文摘 | Jackman SV Docimo SG | 1998 | World J Urol1998，16，： | 1 |
| 14 | The 'mini-prec' technique: The 'mini-pere' technique : a less invasive alternative to pereutaneous nephrolithot- omy显示文摘 | Jackman S V Docimo S G Cadeddu J A | 1998 | WorldJ Uroh1998，16，6： | 1 |
| 15 | Endourological management of pediatric stone disease:Present status显示文摘 | Smaldone MC Corcoran AT Docimo SG | 2009 | J Urol2009，181，1： | 1 |
| 16 | MinimaLLy invasive surgery for uroLogic disease in chiLdren显示文摘 | DanieLLe D Sweeney Marc C SmaLdone and Steven G Docimo | 2007 | NATURE CLINICAL PRACTICE2007，4，： | 1 |
| 17 | The 'mini-pere' technique: a less invasive alternative to percutaneous nephrolithotomy显示文摘 | Jackan SV Docimo SG Cadeddu JA | 1998 | Word J Uro11998，16，6： | 1 |
| 18 | The 'mini-perc' technique:a less invasive alternative to percutaneous nephrolithotomy显示文摘 | Jackman SV Docimo SG Cadeddu JA | 1998 | World Urol1998，16，： | 1 |
| 19 | The 'mini-perc' technique: a less invasive alternative to percutaneous nephrolithoto- my显示文摘 | Jackman SV Docimo SG Cadeddu JA | 1998 | World J Urol1998，16，6： | 1 |
| 20 | The mini-perc technique:a less invasive alternative to percutaneous nephrolitho tomy显示文摘 | Jackman SV Docimo SG Cadeddu JA | 1998 | World J Urol1998，16，6： | 1 |
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