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11篇 您的检索式:作者名="Ghawi"
    题名 作者 年代 出处 被引量
1热带水蛭Hirudinaria manillensis睡液提取物的体内降糖作用(英文)显示文摘The anticoagulant effect of leech saliva was traditionally employed in the treatment of diabetes mellitus complications such as peripheral vascular complications.This study was carried out to examine the effect of leech saliva extract(LSE)on blood glucose levels in alloxan-induced diabetic rats.First,LSE was collected from leeches which were fed on a phagostimulatory solution.Second,total protein concentration was estimated using the Bradford assay.Third,diabetic rats were injected subcutaneously(sc)with LSE at doses of 500 and 1 000μg·kg 1body weight(bw).Other diabetic rats were injected sc with insulin at doses of 10 and 20 U·kg 1bw.Another group was injected simultaneously with LSE(250μg·kg 1bw)and insulin(10 U·kg 1bw).Fasting blood glucose(FBG)concentrations were monitored during a study period of eight hours at regular intervals.Findings showed that both doses of LSE resulted in a significant and gradual decrease in FBG starting from 10%18%downfall after two hours of injection reaching the maximal reduction activity of 58%after eight hours.Remarkably,LSE was sufficient to bring the rats to a near norm-glycemic state.The high dose of insulin induced a severe hypoglycemic condition after 2 4 h of injection.The lower dose was able to decline FBG for 2 6 h in rats which became diabetic again after 8 h.On the other hand,the concurrent injection of low doses of LSE and insulin produced a hypoglycemic effect with all rats showing normal FBG levels.Taken together,these findings indicated that the subcutaneous injection of LSE of the medicinal Malaysian leech was able to provide better glycemic control compared with insulin.Moreover,the synergism between LSE and insulin suggests that LSE could be utilized as an adjuvant medication in order to reduce insulin dosage or to achieve better control of blood glucose.Abdualkader Abdualrahman Mohammed Ghawi Abbas Mohammad Alaama Mohamed Awang Mohamed Merzouk Ahmed 2013中国天然药物2013,11,5:3
2Fetal Left and Right Ventricle Myocardial Performance Index: Defining Normal Values for the Second and Third Trimesters—Single Tertiary Center Experience显示文摘Hani Ghawi Salwa Gendi Kiran Mallula Mohammed Zghouzi Nadeen Faza Sawsan Awad 2013Pediatric Cardiology2013,,8:2
3Anticancer effects of medical Malaysian leech saliva extract LSE 显示文摘Merzouk A Ghawi AM Abdualkader AM 2012Pharm Anal Acta2012,,15:1
4Fetal left and rightventricle myocardial performance index : defining normalvalues for the second and third trimesters -single tertiarycenter experience 显示文摘Ghawi H Gendi S Mallula K 2013Pediatr Cardiol2013,34,8:1
5Fetal left and right ventricle myocardial performance index: defining normal values for the second and third trimesters--single tertiary center experience显示文摘Ghawi H Gendi S Mallula K 2013Pediatr Cardiol2013,34,8:1
6Leech Therapeutic Applications 显示文摘Abdualkader AM Ghawi AM Alaama M 2013Indian J Pharm Sci2013,75,2:1
7Free radical scavenging activity of the medicinal Malaysian leech saliva extract, Hirudinaria manillensis 显示文摘Ghawi AM Abdualkader AM Merzouk A 2012J Bioequiv Bioavail2012,14,:1
8Effect of plastic mulches on soil water conservation and soil temperature in field growth tomato in the Jordan Valley显示文摘HADDADIN S H GHAWI I 1983Dirasat1983,,13:1
9A novel measure of socioeconomic status using individual housing data to assess the association of SES with rheumatoid arthritis and its mortality: a population-based case-control study 显示文摘Ghawi H Crowson CS Rand-Weaver J 2015BMJ Open2015,5,00:1
10Determination of selenium in Libyan food items using pseudo-ocyclic in strumental neut ton activation analysis 显示文摘EL GHAWI U M AL-SADEQ A A BEJEY M M 2005Biological Trace Element Research2005,107,1:1
11Watermelon Production under Mulch and Trickle Irrigation in the Jordan Valley 显示文摘GHAWI I BATI'IKHI A 1986Journal of Agronomy and Crop Science1986,157,:1
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