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| 1 | Liver transplantation and BCLC classification:Limitations impede optimum treatment显示文摘Background:The Barcelona Clinic Liver Cancer(BCLC)system has been endorsed by international guidelines as a staging algorithm of hepatocellular carcinoma.This analysis was performed to assess the outcome of liver transplantation in patients treated against the BCLC recommendations.Methods:The data of 198 patients who underwent liver transplantation for hepatocellular carcinoma were extracted from a prospectively maintained database to classify the patients according to the BCLC system.Results:BCLC staging was as follows:0,n=5;A,n=77;B,n=41;C,n=53;and D,n=22.Accordingly,liver transplantation was performed in the majority of patients against BCLC recommendations.Surgery(n=16),radiofrequency ablation(n=15)and transarterial chemoembolization(n=151)preceded liver transplantation in 182 patients.Sixteen patients were transplanted without pretreatment.The 1-,5-and 10-year survival rates were 83.8%,62.4%and 45.9%,and 1-,5-,and 10-year recurrence rates were 7.7%,22.7%and 26.7%.The BCLC classification did neither impact survival(P=0.796)nor recurrence(P=0.693).In the Cox analysis,RECIST tumor progression and initial alpha fetoprotein were independent predictors of outcome.Conclusions:Neither the oncological nor the functional stratification imposed by the BCLC system was of importance for outcome.Lack of flexibility and disregard of biological parameters hamper its clinical applicability in liver transplantation. | Gerd Otto Michael B Pitton Maria Hoppe-Lotichius Arndt Weinmann | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，1： | 4 |
| 2 | Some ep- idemiological and economic aspects of a blue- tongue -like disease in cattle in South Africa- 1995/96 and 1997 显示文摘 | Barnard B J Gerdes GH Meiswinkel R | 1998 | Onderstepoort J Vet Res1998，65，3： | 1 |
| 3 | Hodgkinand Sternberg-Reed cells contain antigens specific to latecells of granulopoiesis 显示文摘 | Stein H Uchdnska-Ziegler B Gerdes J | 1982 | Int J Cancer1982，29，3： | 1 |
| 4 | Measuring anterior chamber depth with the orbscan topography system显示文摘 | Manfred R Yaser B | 1997 | J Cataract Refract Surg1997，23，9： | 1 |
| 5 | Antibodies against bo- vine herpesvirus 4 are highly prevalent in wild African buffaloes throughout eastern and southern Africa显示文摘 | Dewals B Gillet L Gerdes T | 2005 | Vet Mierobiol2005，110，34： | 1 |
| 6 | P16INK4a is a prognostic marker in resected ductal pancreatic cancer,an analysis of p16INK4a,p53,MDM2,and Rb显示文摘 | Gerdes B Ramaswamy A Ziegler A | 2002 | Ann Surg2002，235，1： | 1 |
| 7 | Coronary Microembolization 显示文摘 | Rainer S Dietrich B | 2001 | Progress In Cardiovascular Dieases2001，44，： | 1 |
| 8 | Distribution of Clostridium difficile variant toxinotypes and strains with binary toxin genes among clinical isolates in an American hospital显示文摘 | Geric B Rupnik M Gerding DN | 2004 | J Med Microbiol2004，53，9： | 1 |
| 9 | Wnt signaling in polycystic kidney disease显示文摘 | Thomas B Matias S Gerd W | 2007 | J Am Soc Nephrol2007，18，： | 1 |
| 10 | Variation of Apolipoprotein B Gene is Associated with Myocardial Infarciton and Lipoprotein Levels in Danes显示文摘 | TYBIAERG-HANSEN A MORDESTGAARD B G GERDES L U | 1991 | Atherosclerosis1991，89，1： | 1 |
| 11 | New studies on mixed-valence indium(Ⅰ ,Ⅲ) chlorides: the indium-chlorine phase diagram in the 30-50 mole % indium range and the crystal structure of indium chloride (Ins Cl9) 显示文摘 | Gerd M Roger B | 1983 | Zeitschrift fuer Anorganische und Allgemeine Chemie1983，503，： | 1 |
| 12 | Localization of the peritoneal reflection in the pelvis by endorectal uhrasound显示文摘 | Gerdes B Langer P Kopp I | 1998 | Surg Endosc1998，12，12： | 1 |
| 13 | Combating antimicrobial resistance: policy recommendations to save lives 显示文摘 | Infectious Diseases Society of America (IDSA) Spellberg B Blaser M Guidos RJ Boucher HW Bradley JS Eisenstein BI Gerding D Lynfield R Relier LB Rex J Schwartz D Septimus E Tenover FC Gilbert DN | 2011 | Clin Infect Dis2011，52，5： | 1 |
| 14 | p16INK4a is a prognostic marker in resected ductal pancreatic cancer:an analysis of p16INK4a,P53,MDM2,an Rb显示文摘 | Ramaswamy A Ziegler A | 2002 | Ann Surg2002，235，1： | 1 |
| 15 | The results of gynecologic surveillance in families with hereditary nonpolypo sis colorectal cancer 显示文摘 | KETABI Z GERDES AM MOSGAARD B | 2014 | Gynecol Oncol2014，133，3： | 1 |
| 16 | Coronary microembolization 显示文摘 | GERD H RAINER S DIETRICH B | 2001 | Progress in Cardiovasular diseases2001，44，： | 1 |
| 17 | 显示文摘 | GERD L | 1997 | Contact Dermatitis1997，36，3： | 1 |
| 18 | Comparative and basal genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene显示文摘 | LI J B GERDES J M HAYCRAFT C J | 2004 | Cell2004，117，： | 1 |
| 19 | Fluid dynamics of the supercritical fluidized bed显示文摘 | CarstenV Ralph S Gerd B | 2005 | Powder Technology2005，128，13： | 1 |
| 20 | A randomized controlled trial of orbital radiotherapy Versus sham irradiation in patients with mind Graves ophthalmopathy显示文摘 | Prummel MF Terwee C B Gerding MN | 2004 | J Clin Endorcrinol Metab2004，89，1： | 1 |
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