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| 1 | Stem cells and cancer:Evidence for bone marrow stem cells in epithelial cancers显示文摘癌症通常在慢性炎和感染的地点产生。尽管这个协会长被认出了,原因仍然保持不清楚。在胃肠道以内,有与癌症联系的煽动性的条件的许多例子,并且这些包括食管, Helicobacter 感染和胃的癌症的倒流疾病和 Barrettos 腺癌,煽动性的肠疾病和颜色表面的癌症和病毒的肝炎导致肝细胞癌。有由哪个慢性炎被要求了导致在一次无穷的尝试包括提高的增长愈合的癌症的几机制损坏,最近创造 pro-carcinogenic 环境和更多的坚持的煽动性的环境的存在为可以象肿瘤一样贡献肿瘤的基质部件的传播导出髓的干细胞的嫁接的一个角色自己集中。这里,我们在我们在动物模型以及在人理解导出髓的干细胞传播骨头的贡献到肿瘤的形成考察最近的进展。 | Han-Chen Li Calin Stoicov Arlin B Rogers JeanMarie Houghton | 2006 | World Journal of Gastroenterology2006，12，3： | 16 |
| 2 | Metal exposure and Alzheimer's pathogenesis.显示文摘 | Liu G Huang W Moir RD Vanderburg CR Lai B Peng Z Tanzi RE Rogers JT Huang X | 2006 | 中国生物学文摘2006，20，9： | 8 |
| 3 | DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘 | Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D | 2008 | Journal of Clinical Investigation2008，，7： | 2 |
| 4 | Thermal hypersensitivity in a subset of irritable bowel syndrome patients显示文摘AIM:To characterize thermal hypersensitivity in patients with constipation-and diarrhea-predominant irritable bowel syndrome (IBS).METHODS:Thermal pain sensitivity was tested among patients with diarrhea-predominant IBS (D-IBS) and constipation-predominant IBS (C-IBS) compared to healthy subjects.A total of 42 patients (29 female and 13 male;mean age 27.0±6.4 years) with D-IBS;24 patients (16 female and eight male;mean age 32.5±8.8 years) with C-IBS;and 52 control subjects (34 female and 18 male;mean age 27.3±8.0 years) participated in the study.Thermal stimuli were delivered using a Medoc Thermal Sensory Analyzer with a 3 cm × 3 cm surface area.Heat pain threshold (HPTh) and heat pain tolerance (HPTo) were assessed on the left ventral forearm and left calf using an ascending method of limits.The Functional Bowel Disease Severity Index (FBDSI) was also obtained for all subjects.RESULTS:Controls were less sensitive than C-IBS and D-IBS (both at P < 0.001) with no differences between C-IBS and D-IBS for HPTh and HPTo.Thermal hyperalgesia was present in both groups of IBS patients relative to controls,with IBS patients reporting significantly lower pain threshold and pain tolerance at both test sites.Cluster analysis revealed the presence of subgroups of IBS patients based on thermal hyperalgesia.One cluster (17% of the sample) showed a profile of heat pain sensitivity very similar to that of healthy controls;a second cluster (47% of the sample) showed moderate heat pain sensitivity;and a third cluster (36% of the sample) showed a very high degree of thermal hyperalgesia.CONCLUSION:A subset of IBS patients had thermal hypersensitivity compared to controls,who reported significantly lower HPTh and HPTo.All IBS patients had a higher score on the FBDSI than controls.Interestingly,the subset of IBS patients with high thermal sensitivity (36%) had the highest FBDSI score compared to the other two groups of IBS patients. | QiQi Zhou Roger B Fillingim Joseph L Riley Ⅲ G Nicholas Verne | 2009 | World Journal of Gastroenterology2009，15，26： | 2 |
| 5 | Stability and structure of activated macrocyclic ligands with biological applications显示文摘 | Motekaitis R J Rogers B E Reichert D E | 1996 | Inorg Chem1996，35，： | 2 |
| 6 | Intravitreal triamcinolone for refractory diabetic macular edema显示文摘 | Adam Martidis Jay S Duker Paul B Greenberg Adam H Rogers Carmen A Puliafito Elias Reichel Caroline Baumal | 2002 | Ophthalmology2002，，5： | 2 |
| 7 | Laser patterning for the study of MSC cardiogenic differentiation at the single-cell level显示文摘Mesenchymal stem cells(MSCs)have been cited as contributors to heart repair through cardiogenic differentiation and multiple cellular interactions,including the paracrine effect,cell fusion,and mechanical and electrical couplings.Due to heart–muscle complexity,progress in the development of knowledge concerning the role of MSCs in cardiac repair is heavily based on MSC–cardiomyocyte coculture.In conventional coculture systems,however,the in vivo cardiac muscle structure,in which rod-shaped cells are connected end-to-end,is not sustained;instead,irregularly shaped cells spread randomly,resulting in randomly distributed cell junctions.Consequently,contact-mediated cell–cell interactions(e.g.,the electrical triggering signal and the mechanical contraction wave that propagate through MSC–cardiomyocyte junctions)occur randomly.Thus,the data generated on the beneficial effects of MSCs may be irrelevant to in vivo biological processes.In this study,we explored whether cardiomyocyte alignment,the most important phenotype,is relevant to stem cell cardiogenic differentiation.Here,we report(i)the construction of a laser-patterned,biochip-based,stem cell–cardiomyocyte coculture model with controlled cell alignment;and(ii)single-cell-level data on stem cell cardiogenic differentiation under in vivo-like cardiomyocyte alignment conditions. | Zhen Ma Qiuying Liu Huaxiao Yang Raymond B Runyan Carol A Eisenberg Meifeng Xu Thomas K Borg Roger Markwald Yifei Wang Bruce Z Gao | 2013 | Light(Science & Applications)2013，2，1： | 2 |
| 8 | Mineralization and biodegradability enhancement of low level p-nitrophenol in water using Fenton's reagent显示文摘 | Eakalak K Roger B W Hsu T M | 2005 | Journal of Environmental Engineering2005，131，2： | 1 |
| 9 | Wild-type and inter-leukin-10-deficient regulatory T cells reduce effector T-cell-mediated gastreduedenitis in rag2-/- mice, but only wild-type regulatory T cells suppress Helicobacter pylori gastritis 显示文摘 | LEE Chung-wei RAO V P ROGERS A B | 2007 | Infect Immun2007，675，6： | 1 |
| 10 | Optimal auction design显示文摘 | Roger B Myerson | 1981 | Mathematics of Operations Research1981，6，： | 1 |
| 11 | Kinetic basis for the substrate specificity during hydrolysis of phospholipids by secreted phospholipase A2 显示文摘 | ROGERS J YU B Z SERVES S V | 1996 | Biochemistry1996，35，29： | 1 |
| 12 | In vitro replication of mouse hepatitis virus strain A59显示文摘 | Compton J R Rogers D B Holmes K V | 1987 | J Virol1987，61，： | 1 |
| 13 | Creativity and Learning in a Case-based Explainer显示文摘 | Roger C S David B L | 1989 | AI1989，40，13： | 1 |
| 14 | High speed tapping mode atomic force microscopy in liquid using an insulated piezoelectric cantilever显示文摘 | Rogers B Sulchek T Murray K | 2003 | Rev Sci Instrum2003，74，11： | 1 |
| 15 | Root to shoot ratio of crops as influenced by CO2显示文摘 | Rogers H H Prior S A Runion G B | 1996 | Plant Soil1996，187，： | 1 |
| 16 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 17 | Liver-brain proinflammatory signalling in acute liver failure: Role in the pathogenesis of hepatic encephalopathy and brain edema显示文摘 | Chantal Bémeur Roger F. Butterworth | 2013 | Metabolic Brain Disease2013，，2： | 1 |
| 18 | Identity consequences of attachment to mothers and fathers among late adolescents显示文摘 | Benson M J Harris P B Rogers C S | | 0，，02： | 1 |
| 19 | Characteristic Impedance De-termination Using Propagation Constant Measurement显示文摘 | Roger B M Dylan F W | 1991 | IEEE Microwave and Guided Wave Letters1991，，1： | 1 |
| 20 | Distribution functions of copulas:a class of bivariate probability integral transforms显示文摘 | Roger B N Quesada-Molina J J Rodriguez-Lallena J A | 2001 | Statistics and Probability Letters2001，54，3： | 1 |
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