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| 1 | Effect of itopride, a new prokinetic, in patients with mild GERD: A pilot study显示文摘AIM: Itopride is a newly developed prokinetic agent, which enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions. The importance of esophageal motor dysfunction in the pathogenesis of gastro-esophageal reflux disease (GERD) makes it interesting to examine the effect of itopride on esophageal acid exposure.METHODS: The effect of itopride on esophageal acid reflux variables for 24 h was studied in 26 patients with GERD symptoms, pre-entry total acid exposure time (pH<4) of more than 5% and mild esophagitis (SavaryMiller grades Ⅰ, Ⅱ) proven by endoscopy. Ambulatory 24-h pH-metry and symptom assessment were performed after treatments with 150 or 300 mg itopride thrice a day (t.i.d.) for 30 d in random order, using an open label method.For evaluating the safety of itopride, blood biochemical laboratory test was performed and the serum prolactin level was also examined before and after treatment.RESULTS: Total symptom score was significantly decreased after treatment in 150- or 300-mg group. Itopride 300mg was significantly effective than 150 mg on decreasing the total per cent time with pH<4, total time with pH<4and DeMeester score. No serious adverse effects were observed with administration of itopride in both groups.CONCLUSION: Itopride 100 mg t.i.d, is effective on decreasing pathologic reflux in patient with GERD and therefore it has the potential to be effective in the treatment of this disease. | Yong Sung Kim Tae Hyeon Kim Chang Soo Choi Young Woo Shon Sang Wook Kim Geom Seog Seo Yong Ho Nah Myung Gyu Choi Suck Chei Choi | 2005 | World Journal of Gastroenterology2005，11，27： | 15 |
| 2 | Long-term follow up of endoscopic resection for type 3 gastric NET显示文摘AIM:To clarify the short and long-term results and to prove the usefulness of endoscopic resection in type 3gastric neuroendocrine tumors(NETs).METHODS:Of the 119 type 3 gastric NETs diagnosed from January 1996 to September 2011,50 patients treated with endoscopic resection were enrolled in this study.For endoscopic resection,endoscopic mucosal resection(EMR)or endoscopic submucosal dissection(ESD)was used.Therapeutic efficacy,complications,and follow-up results were evaluated retrospectively.RESULTS:EMR was performed in 41 cases and ESD in 9 cases.Pathologically complete resection was performed in 40 cases(80.0%)and incomplete resection specimens were observed in 10 cases(7 vs 3 patients in the EMR vs ESD group,P=0.249).Upon analysis of the incomplete resection group,lateral or vertical margin invasion was found in six cases(14.6%)in the EMR group and in one case in the ESD group(11.1%).Lymphovascular invasions were observed in two cases(22.2%)in the ESD group and in one case(2.4%)in the EMR group(P=0.080).During the follow-up period(43.73;13-60 mo),there was no evidence of tumor recurrence in either the pathologically complete resection group or the incomplete resection group.No recurrence was reported during follow-up.In addition,no mortality was reported in either the complete resection group or the incomplete resection group for the duration of the follow-up period.CONCLUSION:Less than 2 cm sized confined submucosal layer type 3 gastric NET with no evidence of lymphovascular invasion,endoscopic treatment could be considered at initial treatment. | Yong Hwan Kwon Seong Woo Jeon Gwang Ha Kim Jin Il Kim Il-Kwun Chung Sam Ryong Jee Heung Up Kim Geom Seog Seo Gwang Ho Baik Kee Don Choi Jeong Seop Moon | 2013 | World Journal of Gastroenterology2013，19，46： | 14 |
| 3 | Cerebral and pulmonary embolisms after transcatheter arterial chemoembolization for hepatocellular carcinoma显示文摘A cerebral lipiodol embolism is an extremely rare complication of transcatheter arterial chemoem bolization for hepatocellular carcinoma. We present a case of cerebral lipiodol embolism that occurred afte the third arterial chemoembolization, report the clinica and radiological findings, and review the medica literature. | Chang Soo Choi Ki Hoon Kim Geom Seog Seo Eun Young Cho Hyo Jeong Oh Suck Chei Choi Tae Hyeon Kim Haak Cheoul Kim Byung Suk Roh | 2008 | World Journal of Gastroenterology2008，14，30： | 10 |
| 4 | Biological therapy for ulcerative colitis:An update显示文摘Of the diverse biological agents used for patients with ulcerative colitis, the anti-tumor necrosis factor-αagents infliximab and adalimumab have been used in large-scale clinical trials and are currently widely used in the treatment of inflammatory bowel disease patients. Recent studies have indicated that golimumab,oral tofacitinib and vedolizumab reportedly achieved good clinical response and remission rates in ulcerative colitis patients. Thus, we believe that the detailed investigation of various studies on clinical trials may provide important information for the selection of appropriate biological agents, and therefore, we have extensively reviewed such trials in the present study. | Geom Seog Seo Soo-Cheon Chae | 2014 | World Journal of Gastroenterology2014，20，37： | 4 |
| 5 | Etric-process maintenancemodel for a deteriorating system under a randomenvironment显示文摘 | LAM Y ZHANG Y L GEOM A | 2008 | IEEE Transactions on Reliability2008，52，1： | 1 |
| 6 | Effects and regulation of osteopontin in rat hepatic stellate cells显示文摘 | Sung Hee Lee Geom Seog Seo Young Nyun Park Tae Moo Yoo Dong Hwan Sohn | 2004 | Biochemical Pharmacology2004，，12： | 1 |
| 7 | Prevention of traumatic brain injury-induced neuronal death by inhibition of NADPH oxidase activation显示文摘 | Bo Yong Choi Bong Geom Jang Jin Hee Kim Bo Eun Lee Min Sohn Hong Ki Song Sang Won Suh | 2012 | Brain Research2012，，： | 1 |
| 8 | Look how mush feed is wasted 显示文摘 | Geom H | 1997 | Pig International1997，27，2： | 1 |
| 9 | Effects of ranitidine for exercise induced gastric mucosal changes and bleeding显示文摘瞄准:在胃的粘膜变化上并且在在长距离跑步者的官方补给的流血上评估 ranitidine 的效果。方法:24 个长距离跑步者(M:16, F:8,变老:18.2 +/- 1.5 年) 参予了这研究。一张症状问询表,凳子缝玄术测试,并且上面胃肠(官方补给) 内视镜检查法在学习以前在这些题目上被执行。这些题目拿了口头的 ranitidine (150 mg, b.i.d ) 为二个星期。上面的官方补给的内视镜检查法和凳子 Hemoccult 测试在治疗以后被重复。结果:24 个跑步者中的 22 个在药前有至少一上面的官方补给的粘膜损害。内视镜的改进在腐蚀胃炎的 14 个盒子中的十一个和食道炎的 5 个盒子中的四个中被看见。六个题目是在学习以前积极的血红素玄术,但是仅仅在药以后是积极的。结论:胃的粘膜损害并且在长距离跑步者的官方补给的流血似乎被联系到酸相关的因素由常规跑的高水平调停了。Ranitidine 似乎是并且阻止胃的粘膜损害并且官方补给的流血的有效预防。 | Suck Jun Choi Yong Sung Kim Jeong Ryong Chae Hong Kwan Cho Tae Hyeon Kim Young Woo Sohn Yong Leol Oh Geom Seog Seo Yong-Ho Nah Suck Chei Choi | 2006 | World Journal of Gastroenterology2006，12，16： | 1 |
| 10 | SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a显示文摘 | Min-Ju Kim Kyungsook Ahn Seong-Hoon Park Hong-Jun Kang Bong Geom Jang Soo-Jin Oh Sun-Mee Oh Yu-Jin Jeong Jee-In Heo Jun-Gyo Suh Soon Sung Lim Yoon-Jung Ko Sung-Oh Huh Sung Chan Kim Jae-Bong Park Jaebong Kim Jong-Il Kim Sangmee Ahn Jo Jae-Yong Lee | 2009 | FEBS Letters2009，，7： | 1 |
| 11 | Endoscopic resection for duodenal carcinoid tumors: A multicenter, retrospective study显示文摘 | Gwang Ha Kim Jin Il Kim Seong Woo Jeon Jeong Seop Moon Il‐Kwun Chung Sam‐Ryong Jee Heung Up Kim Geom Seog Seo Gwang Ho Baik Yong Chan Lee | 2014 | J Gastroenterol Hepatol2014，，2： | 1 |
| 12 | Seroprevalence of Helicobacter pylori in South Korea显示文摘 | Jeong YoonYim NayoungKim Seung HoChoi Young SunKim Kyung RanCho Sun SinKim Geom SeogSeo Heung UpKim Gwang HoBaik Chan SooSin Sang HeonCho Byung HeeOh | 2007 | Helicobacter2007，，4： | 1 |
| 13 | Etfic-process maintenance model for a deteriorating system under a random environment 显示文摘 | LAM Y ZHANG Y L GEOM A | 2008 | IEEE Trans Reliability2008，52，1： | 1 |
| 14 | Regulation of hydroxyapatite formation by gelatin and type Ⅰ collagen gels显示文摘 | Lumenthal N C Cosma V Geomes E | 1991 | Calcif Tissue Int1991，48，： | 1 |
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