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| 1 | Updated diagnosis, treatment and prevention of COVID-19 in children: experts' consensus statement (condensed version of the second edition)显示文摘In the early February,2020,we called up an experts' committee with more than 30 Chinese experts from 11 national medical academic organizations to formulate the first edition of consensus statement on diagnosis,treatment and prevention of coronavirus disease 2019 (COVID-19) in children,which has been published in this journal.With accumulated experiences in the diagnosis and treatment of COVID-19 in children,we have updated the consensus statement and released the second edition recently.The current version in English is a condensed version of the second edition of consensus statement on diagnosis,treatment and prevention of COVID-19 in children.In the current version,diagnosis and treatement criteria have been optimized,and early identification of severe and critical cases is highlighted.The early warning indicators for severe pediatric cases have been summarized which is utmost important for clinical practice.This version of experts consensus will be valuable for better prevention,diagnosis and treatment of COVID-19 in children worldwide. | Kun-Ling Shen Yong-Hong Yang Rong-Meng Jiang Tian-You Wang Dong-Chi Zhao Yi Jiang Xiao-Xia Lu Run-Ming Jin Yue-Jie Zheng Bao-Ping Xu Zheng-De Xie Zhi-sheng Liu Xing-wang Li Li-Kai Lin Yun-Xiao Shang Sai-Nan Shu Yan Bai Min Lu Gen Lu Ji-Kui Deng Wan-Jun Luo Li-Juan Xiong Miao Liu Yu-Xia Cui Le-Ping Ye Jia-Fu Li Jian-Bo Shao Li-Wei Gao Yong-Yan Wang Xue-Feng Wang | 2020 | World Journal of Pediatrics2020，16，3： | 9 |
| 2 | Hollow spherical rare-earth-doped yttrium oxysulfate: A novel structure for upconversion显示文摘锻烧跟随的一条灵巧的 帮助biomolecule 的热水的线路为空范围与另外的稀土元素的离子做了的单斜晶的钇 oxysulfate 的准备被采用了( Yb <啜class=“ a-plus-plus ”>3+和 Eu <啜class=“ a-plus-plus ”>3+或嗯<啜class=“ a-plus-plus ”>3+)。空范围的形成可以包含 Ostwald 成熟。产生混合材料被用于 upconversion 应用。主人水晶结构允许容易没有显著地改变主人格子,二个不同稀土元素的金属离子共同做。光性质被稀土元素的金属离子由于精力转移和水晶的对称回答的掺杂物的比率和集中影响。光中心的类型和样品的 crystallinity 也被显示在同样准备的产品的光性质上有重要影响。 | Gen Chen Fashen Chen Xiaohe Liu Wei Ma Hongmei Luo Junhui Li Renzhi Ma Guanzhou Qiu | 2014 | Nano Research2014，7，8： | 6 |
| 3 | Performance of compact plastic scintillator strips with wavelength shifting fibers using a photomultiplier tube or silicon photomultiplier readout显示文摘This study presents the design and performance results for compact plastic scintillator strips using a wavelength shifting fiber(WLS-fiber)readout with dimensions of 0.1 m×0.02 m×2 m.This approach was evaluated as a candidate for a cosmic-ray muon detector for the Taishan Antineutrino Observatory(JUNO-TAO).The strips coupled with 3-inch photomultiplier tubes(PMTs)were measured and compared between the single-end and double-end readout options.Additionally,a strip using the double-end option coupling with a silicon photomultiplier(SiPM)was further evaluated and compared with the results obtained using PMTs.The performance of the strips was determined by a detailed survey along their length with a cosmicray muon after detailed characterization of the 3-inch PMTs and SiPMs.The proposed design employing a compact plastic scintillator strip with WLS-fiber coupling to a SiPM provides a good choice for cosmic-ray muon veto detectors,particularly when detector dimensions must be limited. | Min Li Zhi‑Min Wang Cai‑Mei Liu Pei‑Zhi Lu Guang Luo Yuen‑Keung Hor Jin‑Chang Liu Chang‑Gen Yang | 2023 | Nuclear Science and Techniques2023，34，2： | 3 |
| 4 | Bio-inspired synthesis of nanomaterials and smart structures for electrochemical energy storage and conversion显示文摘Traditional synthetic methodologies are confronted with great challenges to fabricate complex nanomaterials with delicate design,high efficiency and excellent sustainability.During the past decade,bio-inspired synthesis has been extensively applied as an effective and efficient strategy for the fabrication of nanomaterials and nanostructures.Mimicking electrode materials at nanoscale in the aspect of either structure or functionality has been receiving surging interest because of their incomparable advantages and outperforming properties.In this review,we summarize the recent progresses on bio-inspired synthesis of nanomaterials and smart structures in the field of energy storage and conversion.Firstly,an overall introduction of bio-inspired synthetic strategies will be presented,with focus on the biotemplates and bio-resources.Following that,a library of complex mimicking structures featured by high-order,hierarchical porosity,or bionic function are introduced,with discussion on their chemical and physical properties associated with the structure.The enhanced electrochemical properties such as energy density,cycling stability,etc.in different electrochemical systems will be also discussed.At last,we will expand the perspectives regarding the advantages and limitations of bioinspired strategy and possible solutions in the future. | Mei Ding Gen Chen Weichuan Xu Chuankun Jia Hongmei Luo | 2020 | Nano Materials Science2020，2，3： | 3 |
| 5 | GEOLOGICAL AND GEOCHEMICAL STUDY ON THE GENESIS OF THE FANKOU Pb-Zn DEPOSIT显示文摘The super large Pb Zn deposit at Fankou is very complex in metallogenic mechanism. Syngenetic brine sedimentation, hot submarine spring eruption—accumulation, syngenetic sedimentation—vadose brine replacement had been supposed as the genetic models before. Under these models, syngenetic mineralization should be dominant in ore formation. However, a series of geological and geochemical properties investigated by authors of this paper are contrary to these models. Therefore, the authors here suggest that this deposit is a typical polygenetic compound ore deposit which share the properties of multistages of geotectonic evolution, multifactors of mineralization control, multisystem of material derivation of mineralization, multimodes of mineralization and multitypes of genesis. | ZHANG Shu gen 1, ZHAN Jian pu 1, HUANG Man xiang 1, FAN Zhong heng 1,WANG Li 1, MA Guo qiu 2, LIU Rui di 2, YANG Han zhuang 2, LIU Sheng bo 2, XU Shui ping 2 and LUO Wen sheng 2 (1. College of Mineral Resource, Environment and | 2001 | Geotectonica et Metallogenia2001，25，1： | 2 |
| 6 | Alkaloids from Stems of Ervatamia yunnanensis (Ⅱ)显示文摘Six indole alkaloids were isolated from the stems of Ervatamia yunnanensis. Among them, 10-hydroxy-19, 20-dihydroisositsirikine (I) is new. The other five are known alkaloids, namely: matrine (II), 19, 20-dihydroisositsirikine (III), 19-s-voacangarine (IV), 11′-methoxyl-19s- heyneanine (V), conodurine (VI). The structural elucidation of the alkaloids was based on spectral means. | Shuang LIANG Xin Gen LUO Hai Sheng CHEN Xiao Dong ZHANG Mao HUANG Wen Yong LIU | 2006 | Chinese Chemical Letters2006，17，6： | 2 |
| 7 | 老年患者经皮冠状动脉介入术后急性肾损伤的早期诊断的研究(英文)显示文摘目的:探索老年患者尿液中肝型脂肪酸结合蛋白(L-FABP)、中性粒细胞明胶酶相关脂质运载蛋白(NGAL)及肾损伤分子1(KIM-1)三种新型肾损伤标志物对经皮冠状动脉介入(PCI)术后急性肾损伤(AKI)的早期预测作用。创新点:本研究主要评估PCI术后肾损伤标志物的上升倍数对AKI早期诊断的价值,对基线标志物水平不同的患者而言,具有一定意义。方法:采用巢式病例对照研究的方法来比较PCI术后AKI患者和对照组患者围手术期肾损伤标志物的变化。结论:老年患者PCI术后6小时尿L-FABP和NGAL的上升倍数对AKI具有一定的预测价值。二者联合检验预测价值更高。而尿KIM-1的早期预测价值较低。 | Hong-hua YE Gen SHEN Qun LUO Fang-fang ZHOU Xiao-ling XIE Chun-yan WANG Li-na HAN | 2018 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2018，19，5： | 2 |
| 8 | Theoretical Mechanistic Studies of Rh-Catalyzed c(sp^3)-H Amination:A Comparison with Co Analogue and Metal Effects显示文摘of main observation and conclusion The mechanism of Rh-catalyzed C(sp^3)—H amination has been computationally investigated.The reaction mechanism mainly involves sequential C(sp^3)—H activation,decarboxylation,nitrene migration insertion,and protonation steps.Competitive concerted metalation deprotonation(CMD)and external base assisted deprotonation(EBAD)pathways are found for the involved C(sp^3)—H activation in both Rh and Co analogous systems.This is different from the previously reported C(sp^2)—H activation,where the CMD is dominant.The key mechanistic difference between the two systems is found to be in the C(sp^3)—H activation step.In comparison with Rh species,the lower activity of Co complex toward the C(sp^3)—H activation could be ascribed to smaller atomic size of Co and thus larger steric repulsion between ancillary ligand and substrate along with the CMD pathway.In view of the EBAD pathway,however,the lower activity of Co species could be imputed to the triplet nature of Co center,which is against the electron transfer from the electron-rich carbon atom of the deprotonating C(sp^3)—H bond to the Co center.As to the subsequent decarboxylation and nitrene insertion steps,compared with the Co system,the relatively lower reactivity of Rh species is partially due to the stronger Rh—N bond,and the higher Ti(Rh—N)and n^*(Rh—N)orbital energies of the corresponding transition state structure. | Yang Yu Gen Luo Jimin Yang Yi Luo | 2020 | Chinese Journal of Chemistry2020，38，12： | 2 |
| 9 | Mass production of Li Fe PO_4/C energy materials using Fe–P waste slag显示文摘To effectively solve the agglomeration problems in the solid state reaction process,pre-adding glucose is adopted to the synthesis of Li Fe PO4/C energy materials using Fe–P waste slag. The average particle & grain size of Li FeP O4/C decreases,and the impurities in Li Fe PO4/C composites reduce to a great extent. It makes great sense to the mass industrial production. The optimum synthesis conditions determined in this work are based on the orthogonal experiments. The samples synthesized in a scale of 500 g exhibit high purity,excellent electrochemical performance,high reaction activity,good reversibility,and low polarization level.The discharge capacities are 145,134,117,and 102 m Ah/g at the current densities of 0.1 C,0.2 C,0.5 C and1 C,respectively. This work puts forward a practical suggestion for mass producing environmental benign and low cost Li FeP O4/C as cathode materials of lithium ion batteries. | Gen Li Pengcheng Wu Chunhui Luo Qian Cui Guixin Wang Kangping Yan | 2015 | Journal of Energy Chemistry2015，24，4： | 2 |
| 10 | miR‐93/Sp7 function loop mediates osteoblast mineralization显示文摘 | Li Yang Peng Cheng Chao Chen Hong‐Bo He Gen‐Qing Xie Hou‐De Zhou Hui Xie Xian‐Ping Wu Xiang‐Hang Luo | 2012 | J Bone Miner Res2012，，7： | 2 |
| 11 | The selective deposition of Fe species inside ZSM-5 for the oxidation of cyclohexane to cyclohexanone显示文摘The design of efficient iron-based catalysts remains a great challenge for selective cyclohexane oxidation to cyclohexanone under mild conditions.Because of the complex distribution of iron location on the support,the selectivity is always low.Here,we report a general strategy to selectively deposit highly-dispersed FeO_(x) into the micropore of ZSM-5 by atomic layer deposition(ALD).The framework of ZSM-5 and the Bronsted acid sites are intact during ALD,and the Fe species are selectively deposited onto the defect and Lewis acid sites of ZSM-5.Besides,more Fe–O–Si bonds are formed over FeO_(x)/ZSM-5 with a low loading of Fe,while FeO_(x) nanoparticles are generated at high Fe loading.They cannot be realized by the traditional solution method.The obtained FeO_(x)/ZSM-5 catalysts perform high selectivity of cyclohexanone(92%–97%),and ALD cycle numbers of FeO_(x) control the activity.Compared with the Fe nanoparticles,the Fe–O–Si species performs higher turnover frequency and stability in the oxidation reaction. | Liming Zhai Bin Zhang Haojie Liang Huibin Wu Xinchun Yang Gen Luo Shichao Zhao Yong Qin | 2021 | Science China Chemistry2021，64，7： | 2 |
| 12 | Children(s) and Adults'Conceptualization and Evaluation of Lying and Truth telling显示文摘 | Fen Xu Yang C Luo Gen yue Fu Kang Lee | | 0，，04： | 1 |
| 13 | Single-cell brain atlas of Parkinson's disease mouse model显示文摘Parkinson's disease(PD)is a neurodegenerative disease,leading to the impairment of movement execution.PD pathogenesis has been largely investigated,either limited to bulk transcriptomic levels or at certain cell types,which failed to capture the cellular heterogeneity and intrinsic interplays among distinct cell types.Here,we report the application of single-nucleus RNA-seq on midbrain,striatum,and cerebellum of theα-syn-A53 T mouse,a well-established PD mouse model,and matched controls,generating the first single cell transcriptomic atlas for the PD model mouse brain composed of 46,174 individual cells.Additionally,we comprehensively depicte the dysfunctions in PD pathology,covering the elevation of NF-k B activity,the alteration of ion channel components,the perturbation of protein homeostasis network,and the dysregulation of glutamatergic signaling.Notably,we identify a variety of cell types closely associated with PD risk genes.Taken together,our study provides valuable resources to systematically dissect the molecular mechanism of PD pathogenesis at the single-cell resolution,which facilitates the development of novel approaches for diagnosis and therapies against PD. | Jixing Zhong Gen Tang Jiacheng Zhu Weiying Wu Ge Li Xiumei Lin Langchao Liang Chaochao Chai Yuying Zeng Feiyue Wang Lihua Luo Jiankang Li Fang Chen Zhen Huang Xiuqing Zhang Yu Zhang Hongde Liu Xin Qiu Shengping Tang Dongsheng Chen | 2021 | Journal of Genetics and Genomics2021，48，4： | 1 |
| 14 | Distinct Molecular Motions in a Switchable Chromophore Dielectric 4‐ N , N ‐Dimethylamino‐4′‐ N ′‐methylstilbazolium Trifluoromethanesulfonate显示文摘 | Zhihua Sun Junhua Luo Tianliang Chen Lina Li Ren‐Gen Xiong Ming‐Liang Tong Maochun Hong | 2012 | Adv Funct Mater2012，，23： | 1 |
| 15 | Cerebral glucose metabolic prediction from amnestic mild cognitive impairment to Alzheimer’s dementia:a meta-analysis显示文摘Brain 18F-fluorodeoxyglucose positron emission tomography(FDG-PET)has been utilized to monitor disease conversion from amnestic mild cognitive impairment(aMCI)to Alzheimer’s dementia(AD).However,the conversion patterns of FDG-PET metabolism across studies are not conclusive.We conducted a voxel-wise meta-analysis using Seed-based d Mapping that included 10 baseline voxel-wise FDG-PET comparisons between 93 aMCI converters and 129 aMCI nonconverters from nine longitudinal studies.The most robust and reliable metabolic alterations that predicted conversion from aMCI to AD were localized in the left posterior cingulate cortex(PCC)/precuneus.Furthermore,meta-regression analyses indicated that baseline mean age and severity of cognitive impairment,and follow-up duration were significant moderators for metabolic alterations in aMCI converters.Our study revealed hypometabolism in the left PCC/precuneus as an early feature in the development of AD.This finding has important implications in understanding the neural substrates for AD conversion and could serve as a potential imaging biomarker for early detection of AD as well as for tracking disease progression at the predementia stage. | Hai Rong Ma Li Qin Sheng Ping Lei Pan Gen Di Wang Rong Luo Hai Cun Shi Zhen Yu Dai Jian Guo Zhong | 2018 | Translational Neurodegeneration2018，7，1： | 1 |
| 16 | Alkaloids from stems of Ervatamia yunnanensis显示文摘Six indole alkaloids were isolated from the stems of Ervatamia yunnanensis. Among them, yunnanensine (I) is new. The other five are known alkaloids, namely: 19,20-E-vallesamine (II), 19s-heyneanine (HI), ibogaine (IV), ibogamine (V), coronaridine (VI). The structural elucidation of the alkaloids was based on spectral means. | Xin Gen Luo Hai Sheng Chen Shuang Liang Mao Huang Wei Dong Xuan Li Jin | 2007 | Chinese Chemical Letters2007，18，6： | 1 |
| 17 | Study on relative collection efficiency of PMTs with spotlight显示文摘nd Photon detection efficiency is a key parameter of PMTs in high-precision neutrino and dark matter experiments,while normally the quantum efficiency is used with a normalization factor and angular response as the detection efficiency,where it is always coupled with detector response from the calibration normalization.Here,the absolute photon detection efficiency of 20′′PMTs in photon-counting level is further considered rather than the combination of quantum efficiency and normalization factors.Purpose and method In order to have a good understanding of photon detection efficiency of the large-area PMT,we conduct a detailed comparison of relative collection efficiencies of a series of PMTs with spotlight.This study is based on the tests of relative quantum efficiency and relative detection efficiency,checked with several light intensities.Conclusion All the results are consistent in relative QE and DE measurement with different light intensities,and the error of each parameter is coupled in our studies.Based on the measurements,Hamamatsu R12860 shows the maximum collection efficiency with spotlight at PMT center,and Hamamatsu R12199,R1355 and HZC XP72B22 have the same level of CE within the uncertainty.Discussion Following the configuration on incident light and DE definition,we can further define the DE of a large-area PMT with similar algorithms,which will also be used for detector simulation in JUNO. | Hai‑qiong Zhang Zhi‑min Wang Feng‑jiao Luo An‑bo Yang Zhong‑Hua Qin Chang‑gen Yang Yue‑kun Heng | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 18 | Investigation of EM scattering from electrically large sea surface with breaking wave at low grazing angles显示文摘 | Gen Luo Min Zhang Xiao-Feng Yuan | 2013 | Waves in Random and Complex Media2013，，3： | 1 |
| 19 | Diagnosis,treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children:experts'consensus statement updatedforthe Omicron variant显示文摘It has been more than 3 years since the novel coronavirus(SARS-CoV-2)pandemic raged globally.The coronavirus disease 2019(COVID-19)has greatly influenced human society.According to data from the World Health Organization(WHO),there were over 656 million confirmed cases of COVID-19 in the world as of January 1,2023,including over 6.6 million deaths[1]. | Rong-Meng Jiang Zheng-De Xie Yi Jiang Xiao-Xia Lu Run-Ming Jin Yue-Jie Zheng Yun-Xiao Shang Bao-Ping Xu Zhi-Sheng Liu Gen Lu Ji-Kui Deng Guang-Hua Liu Xiao-Chuan Wang Jian-She Wang Lu-Zhao Feng Wei Liu Yi Zheng Sai-Nan Shu Min Lu Wan-Jun Luo Miao Liu Yu-Xia Cui Le-Ping Ye A-Dong Shen Gang Liu Li-Wei Gao Li-Juan Xiong Yan Bai Li-Kai Lin Zhuang Wei Feng-Xia Xue Tian-You Wang Dong-Chi Zhao Jian-Bo Shao Daniel Kwok-keung Ng Gary Wing-kin Wong Zheng-Yan Zhao Xing-Wang Li Yong-Hong Yang Kun-Ling Shen | 2024 | World Journal of Pediatrics2024，20，3： | 0 |
| 20 | Oxytocin receptor variant rs53576 genotype is associated with dysphoric arousal symptoms of DSM-5 posttraumatic stress disorder in Chinese earthquake survivors显示文摘Purpose:Evidence suggests that the oxytocin receptor(OXTR)gene may be involved in the psychopathology of posttraumatic stress disorder(PTSD).This study aimed to investigate the effects of OXTR rs53576 genotype on PTSD symptoms introduced in the Diagnostic and Statistical Manual,Fifth Edition(DSM-5).Methods:This study was a cross-sectional study conducted among 1140 adults who had personally experienced the Wenchuan earthquake.PTSD symptoms were measured with the PTSD checklist for DSM-5.A custom-by-design 2×48-Plex SNPscan TM Kit were used to determine the OXTR rs53576.Multiple regression models were used to analyze the independent and interactive effects of OXTR rs53576 genotype and earthquake exposure on the severity of total PTSD symptoms and different dimensions of PTSD symptoms.Results:The results revealed that the rs53576 genotype could significantly predict PTSD symptoms(β=0.055,p=0.045).Further analysis showed that the rs53576 genotype was only significantly associated with dysphoric arousal symptoms of PTSD(β=0.080,p=0.005).The rs53576 genotype×earthquake exposure interaction had no significant effect on different symptom clusters(p>0.05).Conclusion:This study showed that the rs53576 genotype was only associated with the dysphoric arousal symptoms but not with other symptom clusters of PTSD.These findings support the role of the OXTR on the psychopathology of PTSD and help us to understand the genetic basis of PTSD. | Cheng-Qi Cao Li Wang Ruo-Jiao Fang Gen Li Ping Liu Shu Luo Xiang-Yang Zhang | 2021 | Chinese Journal of Traumatology2021，24，4： | 0 |
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