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| 1 | 2018 update of expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI显示文摘East Asians are the most populous race in the world and their health status is an important global issue.Compared with Caucasian populations, East Asian patients have a different benefit/risk ratio when using antithrombotic treatment. Despite this observation, treatment strategies in East Asian patients are mostly based on the American and European guidelines. Despite a lower platelet inhibitory response to clopidogrel, East Asian patients show a similar or even a lower rate of ischemic event occurrence and higher bleeding risk compared with Caucasian patients. For potent P2Y_(12) inhibitors(ticagrelor and prasugrel),East Asian patients have shown less favorable net clinical benefits compared with Caucasian patients,which may be related to differences in pharmacokinetic/pharmacodynamic profiles and therapeutic zone of antiplatelet effect. This updated consensus mainly focuses on state-of-the-art and current controversies in the East Asian population. In addition, when East Asian patients are administered potent P2Y_(12) receptor inhibitors, the strategies and ongoing trials to overcome the related hurdles are discussed. | Yong Huo Young-Hoon Jeong Yanjun Gong Daowen Wang Ben He Jiyan Chen Guosheng Fu Yundai Chen Jianping Li Yi Li Shinya Goto Udaya S.Tantry Paul A.Gurbel Jong-Hwa Ahn Hyo-Soo Kim Myung Ho Jeong Yaling Han Sidney C.Smith Jr. Junbo Ge | 2019 | Science Bulletin2019,64,3: | 12 |
| 2 | Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer显示文摘胃的癌症是世界范围的最普通的恶意之一;然而,在 tumorigenesis 的分子的机制仍然需要探索。BCL2L11 属于 BCL-2 家庭,并且充当内在的 apoptotic 串联的一个中央管理者并且调停房间 apoptosis。尽管 miRNAs 被报导了涉及癌症开发的每个阶段,在 GC 的 miR-24 的角色还没被报导。在现在的学习,当 BCL2L11 的表示在 GC 的肿瘤纸巾被禁止时, miR-24 被发现起来调整。研究从在 vitro 并且在显示出的 vivo,那 miR-24 调整 BCL2L11 表示由与 mRNA 的 3UTR 直接有约束力,因此支持房间生长,移植当禁止房间 apoptosis 时。因此, miR-24 是能是为未来的潜在的药目标的新奇 onco-miRNA 临床的使用。 | Haiyang Zhang Jingjing Duan Yanjun Qu Ting Deng Rui Liu Le Zhang Ming Bai Jialu Li Tao Ning Shaohua Ge Xia Wang ZhenzhenWang~ Qian Fan Hongli Li Guoguang Ying Dingzhi Huang Yi Ba | 2016 | Protein & Cell2016,7,2: | 11 |
| 3 | Exploring Seasonal and Circadian Rhythms in Structural Traits of Field Maize from LiDAR Time Series显示文摘Plant growth rhythm in structural traits is important for better understanding plant response to the ever-changing environment.Terrestrial laser scanning(TLS)is a well-suited tool to study structural rhythm under field conditions.Recent studies have used TLS to describe the structural rhythm of trees,but no consistent patterns have been drawn.Meanwhile,whether TLS can capture structural rhythm in crops is unclear.Here,we aim to explore the seasonal and circadian rhythms in maize structural traits at both the plant and leaf levels from time-series TLS.The seasonal rhythm was studied using TLS data collected at four key growth periods,including jointing,bell-mouthed,heading,and maturity periods.Circadian rhythms were explored by using TLS data acquired around every 2 hours in a whole day under standard and cold stress conditions.Results showed that TLS can quantify the seasonal and circadian rhythm in structural traits at both plant and leaf levels.(1)Leaf inclination angle decreased significantly between the jointing stage and bell-mouthed stage.Leaf azimuth was stable after the jointing stage.(2)Some individual-level structural rhythms(e.g.,azimuth and projected leaf area/PLA)were consistent with leaf-level structural rhythms.(3)The circadian rhythms of some traits(e.g.,PLA)were not consistent under standard and cold stress conditions.(4)Environmental factors showed better correlations with leaf traits under cold stress than standard conditions.Temperature was the most important factor that significantly correlated with all leaf traits except leaf azimuth.This study highlights the potential of time-series TLS in studying outdoor agricultural chronobiology. | Shichao Jin Yanjun Su Yongguang Zhang Shilin Song Qing Li Zhonghua Liu Qin Ma Yan Ge LingLi Liu Yanfeng Ding Frédéric Baret Qinghua Guo | 2021 | Plant Phenomics2021,3,1: | 5 |
| 4 | Study of the Reservoir Damage during Cyclic Injection and Extraction Process in the Hutubi Gas Storage显示文摘During the injection and extraction process in gas storage,cyclic loading stress is applied to the reservoir pore structure,affecting the capacity and service life of gas storage. To study the influence of cyclic injection and extraction on reservoir physical property,a finite-element model of reservoir elastoplastic damage under the effect of pore pressure is established based on elastoplastic mechanics and fatigue-damage mechanics. Considering the mechanical property of the Hutubi reservoir and the injection-extraction mode of gas storage,the finite-element model is used to study the pore pressure and porosity change,fault safety,and ground surface deformation. The results show that the change in pore pressure and porosity,the deformation of the Hutubi fault,as well as the uplift and sink of the grounds surface are controlled by the fatigue damage of the reservoir pore structure during the injection-extraction process. After a 6-year service life, the cumulative deformation of the reservoir pore reaches its limit,causing pore structure collapse and porosity decrease. As a result,storage capacity declines and the ground surface starts to sink. Through this study,the safety of the Hutubi gas storage is evaluated,and some suggestions for field operations are offered. | Wang Jianbo Ge Hongkui Wang Xiaoqiong Liu Tongyuan Liu Dunqing Zhang Yanjun Wu Shan | 2018 | Earthquake Research in China2018,32,2: | 4 |
| 5 | Evaluating urban expansion and land use change in Shijiazhuang, China, by using GIS and remote sensing显示文摘 | Jieying Xiao Yanjun Shen Jingfeng Ge Ryutaro Tateishi Changyuan Tang Yanqing Liang Zhiying Huang | 2005 | Landscape and Urban Planning2005,,1: | 3 |
| 6 | A three dimensional analytical of the air-gap magnetic field and torque of coaxial magnetic gears显示文摘 | Ge Yanjun Nie Chongyang Xin Qiang | 2012 | Progress in Electromagnetic Research2012,131,2: | 1 |
| 7 | Evaluating urban expansion and land use change in Shijiazhuang,China,by using GIS and remote sensing 显示文摘 | Xiao Jieying Shen Yanjun Ge Jingfeng | 2006 | Landscape and Urban Planning2006,75,: | 1 |
| 8 | Evaluating urban expansion and land use change in Shijiazhuang,China,by using GIS and remote sensing显示文摘 | Xiao Jieying Shen Yanjun Ge Jingfeng | 2005 | Landscape and Urban Planning2005,,4: | 1 |
| 9 | Evaluating urban expansion and land use change in Shijiazhuang,China,by using GIS and remote sensing显示文摘 | Xiao Jieying Shen Yanjun Ge Jingfeng | 2005 | Landscape and Urban Planning2005,,4: | 1 |
| 10 | Evaluating urban expansion and land use change in Shijiazhuang,China,by using GIS and remote sensing显示文摘 | Xiao Jieying Shen Yanjun Ge Jingfeng | 2006 | Landscape and Urban Planning2006,75,: | 1 |
| 11 | Exper- imental Investigation on a One-Rotor Two-Stage Rotary Desiccant Cooling System 显示文摘 | Ge Tianshu Dai Yanjun Wang Ruzhu Li Yong | 2008 | Energy2008,33,12: | 1 |
| 12 | Evaluating urban expansion and land use change in Shijiazhuang, China, by using GIS and remote sensing显示文摘 | XIAO Jieying SHEN Yanjun GE Jingfeng | | 0,,04: | 1 |
| 13 | Evaluating urban expansion and land use change in Shijiazhuang,China,by using GIS and remote sensing显示文摘 | Xiao Jieying Shen Yanjun Ge Jingfeng | | 0,,01: | 1 |
| 14 | Evaluating urban expansion and land use change in Shijiazhuang, China, by usingGIS and remote sening显示文摘 | Jieying Xiao Yanjun Shen Jingfeng Ge | 2006 | Landseap and urban planning2006,75,12: | 1 |
| 15 | Proximity Chemistry in Living Systems显示文摘Enzyme-and catalyst-generated reactive species have been leveraged in the past decade to covalently label biomolecules within a short range of a defined site or space inside cells or at the cell–cell interface.Due to their high spatial resolution,such proximity labeling strategies have been coupled with various bioanalytical techniques for dissecting dynamic and complex biological processes.Here,we review the development of enzyme-and catalyst-triggered proximity chemistry and their applications to identifying protein interaction networks as well as cell–cell communications in living systems. | Yanjun Liu Yun Ge Ruxin Zeng William Shu Ching Ngai Xinyuan Fan Peng R.Chen | 2023 | CCS Chemistry2023,5,4: | 0 |