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| 1 | 输尿管硬镜辅助的可视化输尿管通道鞘放置方法的初步应用显示文摘目的:为提高输尿管通道鞘(ureteral access sheath,UAS)放置过程的安全性和准确性,本研究尝试利用输尿管硬镜辅助实现置鞘过程的可视化,并与国内常用的徒手置鞘法进行对比,比较手术操作的安全性和有效性。方法:将94例符合纳入标准的肾结石或输尿管上段结石患者,随机分为A、B两组。A组患者采用输尿管硬镜辅助的可视化置鞘法:将14/12Fr 35cm UAS套在9.5Fr 43cm输尿管硬镜上,在直视下进镜并将UAS放置到输尿管合适位置,退出硬镜再进行软镜碎石术。B组患者采用无X线监视的徒手置鞘法。UAS置入后两组采用相同的技术进行碎石。记录术中UAS放置情况和时间、输尿管损伤情况,随访4~12周,了解清石率及术后并发症情况。结果:与B组比较,A组UAS放置所需时间更短[(35.69±6.54)s vs.(55.71±10.58)s,P<0.05]。在术前预先留置双J管的患者中两组置鞘成功率均为100%,在术前未预先留置双J管的患者中B组置鞘成功率高于A组(83.33%vs.66.67%,P<0.05)。两组手术时间差异无统计学意义[(65.31±24.45)min vs.(67.42±21.34)min,P>0.05]。A组在术中发生输尿管1级损伤1例;B组在术中发生输尿管1级损伤4例,2级损伤1例;3级损伤1例,输尿管损伤发生率A组显著低于B组(2.08%vs.13.04%,P<0.05)。两组住院时间差异无统计学意义[(4.08±1.45)d vs.(4.16±1.37)d,P>0.05]。两组一期结石清除率差异无统计学意义(91.67%vs.89.13%,P>0.05)。结论:输尿管硬镜辅助的可视化置鞘法安全可行,可控性好,与徒手置鞘法相比能提高操作的安全性和准确性。局限性在于对于术前未预先留置双J管的患者,输尿管硬镜辅助的可视化置鞘法置鞘成功率有所降低。 | 刘卓 江弘炀 刘夏铭 Gaurab Pokhrel 李聪 王涛 余虓 王少刚 刘继红 | 2018 | 临床泌尿外科杂志2018，33，7： | 5 |
| 2 | GENCODE: The reference human genome annotation for The ENCODE Project显示文摘 | Jennifer Harrow Adam Frankish Jose M. Gonzalez Electra Tapanari Mark Diekhans Felix Kokocinski Bronwen L. Aken Daniel Barrell Amonida Zadissa Stephen Searle If Barnes Alexandra Bignell Veronika Boychenko Toby Hunt Mike Kay Gaurab Mukherjee Jeena Rajan Glo | 2012 | Genome Research2012，，9： | 2 |
| 3 | Sex detection of Carica papaya and Cycascircinalis in pre-flowering stage by ISSR and RAPD 显示文摘 | Gaurab G Subhash K R Kaushik G | 2007 | Current Science2007，92，4： | 1 |
| 4 | A DSC study of poly (styrene-co- acrylonitrile) and poly (vinyl chloride-co-vinyl acetate) blends produced using different blending techniques显示文摘 | Das Gaurab Banerjee A N Mitra B C | 1996 | Eur Polym J1996，32，2： | 1 |
| 5 | A cDNA-AFLP approach to look for differentially expressed gene fragments in dioecious pointed gourd (Trichosanthes dioica Roxb显示文摘 | Subhash KR Gaurab G | 2008 | Biochemical Biophys Res Commun2008，，94： | 1 |
| 6 | Effects of salt and osmotic shocks on unadapted and adapted callus lines of tobacco显示文摘 | Gaurab Gangopadhyay Sangita Basu Barid Baran Mukherjee Sukumar Gupta | 1997 | Plant Cell Tissue and Organ Culture1997，，1： | 1 |
| 7 | Testosterone undecanoate supplementation together with human chorionic gonadotropin does not impair spermatogenesis in males with isolated hypogonadotropic hypogonadism:a retrospective study显示文摘Gon adotropin therapy is comm only used to in duce virilizati on and spermatoge nesis in male isolated hypog on adotropic hypog on adism (IHH) patients. In clinical practice, 5.6%-15.0% of male IHH patients show poor responses to gonadotropin treatment;therefore, testosterone (T) suppleme ntation can serve as an alter native therapy to no rmalize serum T levels and promote virilization. However, treatment with exogenous T impairs spermatogenesis and suppresses intratesticular T levels. This retrospective study aimed to determine whether oral testosterone undeca noate (TU) suppleme ntation together with human chorionic gonadotropin (hCG) would negatively affect spermatogenesis in IHH patients compared with hCG alone. One hundred and seven IHH patients were included in our study. Fifty-four patients received intramuscular hCG and oral TU, and 53 patients received intramuscular hCG alone. The median follow-up time was 29 (range: 12-72) mon ths in both groups. Compared with the hCG group, the hCG/TU group required a shorter median time to normalize serum T levels (P < 0.001) and achieve Tanner stage (III and V) of pubic hair and genital development (P < 0.05). However, there were no significant differences in the rate of seminal spermatozoa appearance, sperm concentration, or median time to achieve different sperm concentration thresholds between the groups. In addition, there were no significant differences in side effects, such as acne and gynecomastia, observed in both groups. This study indicates that oral TU supplementation together with hCG does not impair spermatogenesis in treated IHH patients compared with hCG alone, and it shortens the time to normalize serum T levels and promote virilization. | Yin-Wei Chen Yong-Hua Niu Hao Xu Dao-Qi Wang Hong-Yang Jiang Gaurab Pokhrel Tao Wang Shao-Gang Wang Ji-Hong Liu | 2019 | Asian Journal of Andrology2019，21，4： | 0 |
| 8 | Δ 9-Tetrahydrocannabinol Toxicity and Validation of Cannabidiol on Brain Dopamine Levels: An Assessment on Cannabis Duplicity显示文摘Δ9-tetrahydrocannabinol(THC)of cannabis is the main psychoactive component which is a global significant concern to human health.Evaluation on THC reported its drastic effect on the brain dopaminergic(DAergic)system stimulating mesolimbic DA containing neurons thereby increasing the level of striatal DA.Cannabidiol(CBD),with its anxiolytic and anti-psychotic property,is potent to ameliorate the THC-induced DAergic variations.Legal authorization of cannabis use and its analogs in most countries led to a drastic dispute in the elicitation of cannabis products.With a recent increase in cannabis-induced disorder rates,the present review highlighted the detrimental effects of THC and the effects of CBD on THC induced alterations in DA synthesis and release.Alongside the reported data,uses of cannabis as a therapeutic medium in a number of health complications are also being briefly reviewed.These evaluated reports led to an anticipation of additional research contradictory to the findings of THC and CBD activity in the brain DAergic system and their medical implementations as therapeutics. | Swapnali Chetia Gaurab Borah | 2020 | Natural Products and Bioprospecting2020，10，5： | 0 |
| 9 | Is Retzius-sparing robot-assisted radical prostatectomy associated with better functional and oncological outcomes? Literature review and meta-analysis显示文摘Objective:To evaluate the efficiency,safety and clinical outcomes of Retziussparing robot-assisted radical prostatectomy(RS-RARP)in comparison with the standard RARP.Methods:A systematic search from Web of Science,PubMed,EMBase,Cochrane Library and Google Scholar was performed using the terms“Retzius-sparing”,“Bocciardi approach”and“robot-assisted radical prostatectomy”.Video articles and abstract papers for academic conferences were excluded.Meta-analysis of interested outcomes such as positive surgical margins(PSMs)and continence recovery was undertaken.A comprehensive literature review of all studies regarding Retzius-sparing(RS)approach was conducted and summarized.Results:From 2010 to 2017,11 original articles about RS-RARP approach were retrieved.Of that,only four studies comparing the RS-RARP approach to the conventional RARP were comparable for meta-analysis.Faster overall continence recovery within 1 month after the surgery was noted in the RS group(61%vs.43%;pZ0.004).PSMs of pT2 and pT3 stages were not significantly different between the groups(10.0%vs.7.4%;p Z 0.39 and 13.1%vs.9.5%,p Z 0.56,respectively).Of all the studies,only one reported sexual recovery outcomes after RS treatment in which 40%of the participants achieved sexual intercourse within the first month.Conclusion:Though more technically demanding than the conventional RARP,the RS technique is a safe and feasible approach.This meta-analysis and literature review indicates that RS technique,as opposed to the conventional approach,is associated with a faster continence recovery while PSMs were comparable between the two groups.The limitations of observational studies and the small data in our meta-analysis may prevent an ultimate conclusion.Future well-designed RCTs are needed to validate and confirm our findings. | Najib Isse Dirie Gaurab Pokhrel Wei Guan Mukhtar Adan Mumin Jun Yang Jackson Ferdinand Masau Henglong Hu Shaogang Wang | 2019 | Asian Journal of Urology2019，6，2： | 0 |
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