|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 中国柱花草炭疽病原菌遗传多态性的RAPD分析显示文摘在对中国柱花草炭疽病进行广泛调查和病原采样收集的基础上 ,利用RAPD分子标记技术对 43个代表性菌株进行了基因组DNA分析 ,并与 2 76份国外菌株进行了综合聚类分析。结果表明所用 8个引物的扩增片段位于 0 3~ 2 8kb之间 ,菌株间呈现显著的DNA多态性。以柱花草起源中心———南美的柱花草炭疽菌分类为基础 ,中国柱花草炭疽菌可划分成 3大类型即Ⅱ、Ⅲ、Ⅵ类。中国菌株与来自柱花草起源中心———南美的菌株相比之下 ,其生物多样性和遗传变异性则相对简单。就中国菌株而言海南菌株与广西、广东菌株相比多样性较丰富 ,中国柱花草胶孢炭疽菌正在出现种内遗传分化。从聚类结果看 ,通常来自于同一个地理区域或同一个寄主基因型的菌株聚成一类 ,即同一RAPD聚类组内的菌株通常来自于同一寄主基因型或同一地理区域。说明来自不同寄主基因型或物种的炭疽菌在遗传基因上具有专化性 ,而地理上隔离的国家或地区的柱花草炭疽病原菌各自具有相对独立的进化途径。 | 易克贤 黄俊生 刘国道 Pualine Weeds Sukumar Charkraborty | 2003 | 微生物学报2003，43，3： | 30 |
| 2 | Methane hydrate formation and dissociation in synthetic seawater显示文摘The formation and dissociation of methane gas hydrate at an interface between synthetic seawater (SSW) and methane gas have been experimentally investigated in the present work. The amount of gas consumed during hydrate formation has been calculated using the real gas equation. Induction time for the formation of hydrate is found to depend on the degree of subcooling. All the experiments were conducted in quiescent system with initial cell pressure of 11.14 MPa. Salinity effects on the onset pressure and temperature of hydrate formation are also observed. The dissociation enthalpies of methane hydrate in synthetic seawater were determined by Clausius-Clapeyron equation based on the measured phase equilibrium data. The dissociation data have been analyzed by existing models and compared with the reported data. | Vikash Kumar Saw Iqbal Ahmad Ajay Mandal G.Udayabhanu Sukumar Laik | 2012 | Journal of Natural Gas Chemistry2012，21，6： | 12 |
| 3 | Nature:死亡的肿瘤细胞释放出胞内钾离子来阻断免疫系统显示文摘在一项新的研究中。来自美国国家癌症研究所和英国巴布拉汉研究所的研究人员发现当肿瘤组织死亡时从它当中泄露出来的一种无机离子起着阻止抗肿瘤免疫细胞发挥功能的作用。这一发现为开发调动免疫系统抵抗癌症的疗法提供一种新的方法。相关研究结果在线发表在Nature期刊上。 | Robert Eil, Suman K. Vodnala, David Clever, Christopher A. Klebanoff, Madhusudhanan Sukumar, Jenny H. Pan, Douglas C. Palmer, Alena Gros, Tori N. Yamamoto, Shashank J. Patel, Geoffrey C. Guittard, Zhiya Yu, David S. Schrump, W. Marston Linehan, Nicholas P. Restifo Christopher A. Klebanoff Valentina Carbonaro, Klaus Okkenhaug, Rahul Roychoudhuri | 2016 | 现代生物医学进展2016，16，31： | 12 |
| 4 | Embolization of liver tumors:Past,present and future显示文摘Curative therapies for hepatocellular carcinoma(HCC),such as resection and liver transplantation,can only be applied in selected patients with early tumors.More advanced stages require local or systemic therapies.Resection of HCC offers the only hope for cure.Even in patients undergoing resection,recurrences are common.Chemoembolization,a technique combining intraarterial chemotherapy with selective tumor ischemia,has been shown by randomized controlled trials to be efficacious in the palliative setting.There is now renewed interest in transarterial embolization/transarterial chemoembolization(TACE) with regards to its use as a palliative tool in a combined modality approach,as a neoadjuvant therapy,in bridging therapy before transplantation,for symptomatic indications,and even as an alternative to resection.There have also been rapid advances in the agents being embolized trans-arterially(genes,biological response modifiers,etc.).The current review provides an evidence-based overview of the past,present and future trends of TACE in patients with HCC. | Ashwin Rammohan Jeswanth Sathyanesan Sukumar Ramaswami Anand Lakshmanan Perumal Senthil-Kumar Ulagendra Perumal Srinivasan Ravi Ramasamy Palaniappan Ravichandran | 2012 | World Journal of Radiology2012，4，9： | 11 |
| 5 | Effect of SDS/THF on thermodynamic and kinetic properties of formation of hydrate from a mixture of gases(CH_4+C_2H_6+C_3H_8) for storing gas as hydrate显示文摘In this work, the effect of sodium dodecyl sulfate(SDS) and combined effect of sodium dodecyl sulfate(SDS) and tetrahydrofuran(THF) on thermodynamic and kinetic properties of CH4+C2H6+C3H8hydrate formation have been studied. Four different concentrations of sodium dodecyl sulfate(100 ppm, 500 ppm,1000 ppm and 1500 ppm) have been used to see its effect on phase equilibrium condition and formation kinetics. Though sodium dodecyl sulfate(SDS) does not vary the pressure–temperature condition of hydrate formation, it has a prominent favorable effect on induction time, gas consumption, storage capacity and formation rate. The addition of 3%(mol) tetrahydrofuran(THF) to water + SDS system results in large shifts in phase equilibrium boundary to lower pressure and higher temperature. It has been noticed that the addition of tetrahydrofuran further enhances the formation rate. So the mixture of sodium dodecyl sulfate(SDS) and tetrahydrofuran(THF) can be effectively used as promoter for storing natural gas as hydrate. | Himangshu Kakati Ajay Mandal Sukumar Laik | 2016 | Journal of Energy Chemistry2016，25，3： | 7 |
| 6 | Intrusion Detection System for PS-Poll DoS Attack in 802.11 Networks Using Real Time Discrete Event System显示文摘Wi-Fi devices have limited battery life because of which conserving battery life is imperative. The 802.11 Wi-Fi standard provides power management feature that allows stations(STAs) to enter into sleep state to preserve energy without any frame losses. After the STA wakes up, it sends a null data or PS-Poll frame to retrieve frame(s) buffered by the access point(AP), if any during its sleep period. An attacker can launch a power save denial of service(PS-DoS) attack on the sleeping STA(s) by transmitting a spoofed null data or PS-Poll frame(s) to retrieve the buffered frame(s) of the sleeping STA(s) from the AP causing frame losses for the targeted STA(s). Current approaches to prevent or detect the PS-DoS attack require encryption,change in protocol or installation of proprietary hardware. These solutions suffer from expensive setup, maintenance, scalability and deployment issues. The PS-DoS attack does not differ in semantics or statistics under normal and attack circumstances.So signature and anomaly based intrusion detection system(IDS) are unfit to detect the PS-DoS attack. In this paper we propose a timed IDS based on real time discrete event system(RTDES) for detecting PS-DoS attack. The proposed DES based IDS overcomes the drawbacks of existing systems and detects the PS-DoS attack with high accuracy and detection rate. The correctness of the RTDES based IDS is proved by experimenting all possible attack scenarios. | Mayank Agarwal Sanketh Purwar Santosh Biswas Sukumar Nandi | 2017 | IEEE/CAA Journal of Automatica Sinica2017，4，4： | 5 |
| 7 | Investigation of CRISPR/Cas9-induced SD1 rice mutants highlights the importance of molecular characterization in plant molecular breeding显示文摘Although Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR)/CRISPR-associated 9(Cas9)system has been widely used for basic research in model plants,its application for applied breeding in crops has faced strong regulatory obstacles,due mainly to a poor understanding of the authentic output of this system,particularly in higher generations.In this study,different from any previous studies,we investigated in detail the molecular characteristics and production performance of CRISPR/Cas9-generated SD1(semi-dwarf 1)mutants from T2 to T4 generations,of which the selection of T1 and T2 was done only by visual phenotyping for semidwarf plants.Our data revealed not only on-and off-target mutations with small or lager indels but also exogenous elements in T2 plants.All indel mutants passed stably to T3 or T4 without additional modifications independent on the presence of Cas9,while some lines displayed unexpected hereditary patterns of Cas9 or some exogenous elements.In addition,effects of various SD1 alleles on rice height and yield differed depending on genetic backgrounds.Taken together,our data showed that the CRISPR/Cas9 system is effective in producing homozygous mutants for functional analysis,but it may be not as precise as expected in rice,and that early and accurate molecular characterization and screening must be carried out for generations before transitioning of the CRISPR/Cas9 system from laboratory to field. | Sukumar Biswas Jiaqi Tian Rong Li Xiaofei Chen Zhijing Luo Mingjiao Chen Xiangxiang Zhao Dabing Zhang Staffan Persson Zheng Yuan Jianxin Shi | 2020 | Journal of Genetics and Genomics2020，47，5： | 4 |
| 8 | Discrete Event System Framework for Fault Diagnosis with Measurement Inconsistency:Case Study of Rogue DHCP Attack显示文摘Fault detection and diagnosis(FDD) facilitates reliable operation of systems. Various approaches have been proposed for FDD like Analytical redundancy(AR), Principal component analysis(PCA), Discrete event system(DES) model etc., in the literature. Performance of FDD schemes greatly depends on accuracy of the sensors which measure the system parameters.Due to various reasons like faults, communication errors etc.,sensors may occasionally miss or report erroneous values of some system parameters to FDD engine, resulting in measurement inconsistency of these parameters. Schemes like AR, PCA etc.,have mechanisms to handle measurement inconsistency, however,they are computationally heavy. DES based FDD techniques are widely used because of computational simplicity, but they cannot handle measurement inconsistency efficiently. Existing DES based schemes do not use Measurement inconsistent(MI)parameters for FDD. These parameters are not permanently unmeasurable or erroneous, so ignoring them may lead to weak diagnosis. To address this issue, we propose a Measurement inconsistent discrete event system(MIDES) framework, which uses MI parameters for FDD at the instances they are measured by the sensors. Otherwise, when they are unmeasurable or erroneously reported, the MIDES invokes an estimator diagnoser that predicts the state(s) the system is expected to be in, using the subsequent parameters measured by the other sensors. The efficacy of the proposed method is illustrated using a pumpvalve system. In addition, an MIDES based intrusion detection system has been developed for detection of rogue dynamic host configuration protocol(DHCP) server attack by mapping the attack to a fault in the DES framework. | Mayank Agarwal Santosh Biswas Sukumar Nandi | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，3： | 4 |
| 9 | Identification of Differentially Expressed Genes Associated with Cotton Fiber Development in a Chromosomal Substitution Line(CS-B22sh)显示文摘One of the impediments in the genetic improvement of cotton fiber is the paucity of information about genes associated with fiber development.Availability of chromosome arm substitution line CS- | SOLIMAN Khairy M BOLTON James J SAHA Sukumar JENKINS Johnie N | 2008 | 棉花学报2008，20，S1： | 4 |
| 10 | A comprehensive review of the effect of different kinetic promoters on methane hydrate formation显示文摘Gas hydrates have recently emerged as a better alternative for the production,storage,and transportation of natural gases.However,factors like slow formation rate and limited storage capacity obstruct the possible industrial application of this technique.Different types of promoters and synergists have been developed that can improve the kinetics and storage capacity of gas hydrates.This review focuses on different kinetic promoters and synergists that can be utilized to enhance the storage capacity of hydrates.The main characteristics,structure and the possible limitations of the use of these promoters are likewise portrayed in detail.The relationship between structure and storage capacity of hydrates have also been discussed in the review.Current status of production of gas from hydrates,their restrictions,and future difficulties have additionally been addressed in the ensuing areas of the review. | Ekta Chaturvedi Sukumar Laik Ajay Mandal | 2021 | Chinese Journal of Chemical Engineering2021，34，4： | 3 |
| 11 | Electrospinning of curcumin loaded chitosan/poly (lactic acid) nanofilm and evaluation of its medicinal characteristics显示文摘curcumin 装载了 chitosan/poly (乳的酸)(PLA ) nanofibers 用 electrospinning 被生产。BoxBehnken 试验性的设计被用于变量的优化(1, 0, + 1 编码水平) 相似 chitosan/PLA 力量(% w/v ) , curcumin 力量(% w/v ) 和应用电压(kV ) 到获得一致纤维直径。nanofibers 的形态学被 SEM 显示出。分子的相互作用和 curcumin 的各化学的化合物的存在装载了 chitosan/PLA 纤维被 FTIR 和 EDX 分析描绘。抗氧化剂,药版本并且在 vitro cytotoxicity,测试被执行评估将被用于创伤愈合的 nanofibers 的适用性。在愈合弯屈在切除和切口上学习的 vivo,创伤在给创伤区域的重要减小看是否的老鼠模型上创造了与相比未经治疗。更好愈合的效率能被归因于 curcumin 和 chitosan 的存在。 | Bhaarathi DHURAI Nachimuthu SARASWATHY Ramasamy MAHESWARAN Ponnusamy SETHUPATHI Palanisamy VANITHA Sukumar VIGNESHWARAN~, and Venugopal RAMESHBABU | 2013 | Frontiers of Materials Science2013，7，4： | 2 |
| 12 | 乳腺癌导管内干预的研究进展显示文摘随着对乳腺癌生物学行为的深入认识,乳腺癌的根治术正向微创术式转变。对于早期乳腺癌特别是乳腺导管原位癌(ductal carcinoma in situ,DCIS)或癌前病变的患者,构建创伤性小、全身毒性低的干预措施是目前亟待解决的问题之一。乳腺癌导管内干预是通过乳腺天然的哺乳导管开口,借助合适的载体对乳腺导管系统病变进行诊疗干预,从而实现乳腺癌的微创治疗。将乳腺癌导管内干预与靶向治疗、内分泌治疗及免疫治疗等相结合,有望进一步提高精准治疗效果。结合我国乳腺癌患者临床病理特点,将纳米技术、分子影像技术及基因测序技术有机结合,进行乳腺癌导管内干预的机制研究,是临床应用、基础研究的重点内容之一。本文主要对乳腺癌导管内干预的研究进展进行综述。 | 陈创 王冠楠 Saraswati Sukumar 汪媛 孙圣荣 | 2017 | 中国肿瘤临床2017，44，4： | 2 |
| 13 | AFM-compatible microfluidic platform for affinity- based capture and nanomechanical characterization of circulating tumor cells显示文摘Circulating tumor cells(CTCs)carried by the patient’s bloodstream are known to lead to the metastatic spread of cancer.It is becoming increasingly clear that an understanding of the nanomechanical characteristics of CTCs,such as elasticity and adhesiveness,represents advancements in tracking and monitoring cancer progression and metastasis.In the present work,we describe a combined microfluidic–atomic force microscopy(AFM)platform that uses antibody–antigen capture to routinely isolate and nanomechanically characterize CTCs present in blood samples from prostate cancer patients.We introduce the reversible assembly of a microfluidic device and apply refined and robust chemistry to covalently bond antibodies onto its glass substrate with high density and the desired orientation.As a result,we show that the device can efficiently capture CTCs from patients with localized and metastatic prostate cancer through anti-EpCAM,anti-PSA,and anti-PSMA antibodies,and it is suitable for AFM measurements of captured intact CTCs.When nanomechanically characterized,CTCs originating from metastatic cancer demonstrate decreased elasticity and increased deformability compared to those originating from localized cancer.While the average adhesion of CTCs to the AFM tip surface remained the same in both the groups,there were fewer multiple adhesion events in metastatic CTCs than there were in their counterparts.The developed platform is simple,robust,and reliable and can be useful in the diagnosis and prognosis of prostate cancer as well as other forms of cancer. | Muhammedin Deliorman Farhad K.Janahi Pavithra Sukumar Ayoub Glia Roaa Alnemari Samar Fadl Weiqiang Chen Mohammad A.Qasaimeh | 2020 | Microsystems & Nanoengineering2020，6，1： | 2 |
| 14 | Lineage relationship of CD8^+ T cell subsets is revealed by progressive changes in the epigenetic landscape显示文摘 | Joseph G. Crompton Manikandan Narayanan Suresh Cuddapah Rahul Roychoudhuri Yun Ji Wenjing Yang Shashank J. Patel Madhusudhanan Sukumar Douglas C. Palmer Weiqun Peng Ena Wang Francesco M. Marincola Christopher A. Klebanoff Keji Zhao John S. Tsang Luca Gatt-inoni Nicholas P. Restifo | 2016 | Cellular & Molecular Immunology2016，13，4： | 2 |
| 15 | Robotic partial nephrectomy: the real benefit显示文摘 | Craig Rogers Shyam Sukumar Inderbir S Gill | 2011 | Current Opinion in Urology2011，，1： | 2 |
| 16 | Storm surge simulation along the Meghna estuarine area:an alternative approach显示文摘In this study, numerical prediction of surges associated with a storm was made through the method of lines(MOL) in coordination with the newly proposed RKARMS(4, 4) method for the meghna estuarine region, along the coast of Bangladesh. For this purpose, the vertically integrated shallow water equations(SWEs) in Cartesian coordinates were firstly transformed into ordinary differential equations(ODEs) of initial valued, which were then soloved using the new RKARMS(4, 4) method. Nested grid technique was employed for resolving the complexities of the region of interest with minimum cost. Fresh water discharge through the lower Meghna River was taken into account along the north east corner of the innermost child scheme. Numerical experiments were performed with the severe cyclone on April 1991 that crossed the coast over the study area. Simulated results by the study were found to be in good agreement with some reported data and were found to compare well with the results obtained by the MOL in addition with the classical 4th order Runge-Kutta(RK(4, 4)) method and the standard finite difference method(FDM). | PAUL Gour Chandra SENTHILKUMAR Sukumar PRIA Rana | 2018 | Acta Oceanologica Sinica2018，37，1： | 2 |
| 17 | Experimental and modeling study of kinetics for methane hydrate formation in a crude oil-in-water emulsion显示文摘A low-viscosity emulsion of crude oil in water can be believed to be the bulk of a flow regime in a pipeline.To differentiate which crude oil would and which would not counter the blockage of flow due to gas hydrate formation in flow channels,varying amount of crude oil in water emulsion without any other extraneous additives has undergone methane gas hydrate formation in an autoclave cell.Crude oil was able to thermodynamically inhibit the gas hydrate formation as observed from its hydrate stability zone.The normalized rate of hydrate formation in the emulsion has been calculated from an illustrative chemical affinity model,which showed a decrease in the methane consumption(decreased normalized rate constant) with an increase in the oil content in the emulsion.Fourier transform infrared spectroscopy(FTIR) of the emulsion and characteristic properties of the crude oil have been used to find the chemical component that could be pivotal in selfinhibitory characteristic of the crude oil collected from Ankleshwar,India,against a situation of clogged flow due to formation of gas hydrate and establish flow assurance. | Shranish Kar Himangshu Kakati Ajay Mandal Sukumar Laik | 2016 | Petroleum Science2016，13，3： | 2 |
| 18 | Synthesis of YAG by a citrate-nitrate combustion technique显示文摘 | Roy Sukumar Wang Liwu Sigmund Wolfgang | 1999 | Mater lett1999，39，： | 2 |
| 19 | HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8显示文摘 | Chen H Chung S Sukumar S | 2004 | Mol Cell Biol2004，24，2： | 1 |
| 20 | Robotic partial nephrectomy : the real benefit显示文摘 | Rogers C Sukumar S Gill I | 2011 | Curt Opin Urol2011，21，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员