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| 1 | The Stripe Rust Resistance Gene Yr10 Encodes an Evolutionary-Conserved and Unique CC-NBS-LRR Sequence in Wheat显示文摘对用一条基于地图的克隆途径从摩洛人小麦(Triticum aestivum L.) 孤立的条纹锈的第一棵幼苗或所有阶段抵抗(R) R 基因作为 Yr10 被识别。这基因的克隆 4B 编码一高度,进化保存和唯一的 CCNBSLRR 定序。克隆 4E, Yr10 的一个相当或相同的事物,而是缺乏的抄写开始地点(TSS ) 和通常认为的 TATA 盒子和 CAAT 盒子,是可能的非表示的 pseudogene。克隆 4B 和 4E 是 84% 在 intron 和 LRR 领域相同、分叉。基因 silencing 和 transgenesis 与无毒害、剧毒的条纹锈尽力表明 Yr10 功能的差别与接种一起被使用。Yr10 CCNBSLRR 顺序在在小麦的已知的 CCNBSLRR R 基因之中是唯一的,但是高度保存相当或相同的事物(E = 0.0 ) 包括 Hordeum vulgare 和 Brachypodium distachyon 在 Aegilops tauschii 和另外的 monocots 被识别。相关序列也在玉米的 genomic 数据库被识别,米饭,并且在里面蜀黍。这是在有在它的本国的主人的有限相同,但是与在为条纹锈是主人或非主人的相关 monocots 的众多的相应 R 基因的植物的 CCNBSLRR 抵抗基因的第一份报告。这些结果越过种类代表基因进化和分散的一个唯一的例子。 | Wei Liu Michele Frick Rene Huel Cory L. Nykiforuk Xiaomin Wang Denis A. Gaudet Francois Eudes Robert L. Conner Alan Kuzyk Zhensheng Kang Andre Laroche | 2014 | Molecular Plant2014,7,12: | 21 |
| 2 | Adaptive Pinpoint and Fuel Efficient Mars Landing Using Reinforcement Learning显示文摘Future unconstrained and science-driven missions to Mars will require advanced guidance algorithms that are able to adapt to more demanding mission requirements, e.g. landing on selected locales with pinpoint accuracy while autonomously flying fuel-efficient trajectories. In this paper, a novel guidance algorithm designed by applying the principles of reinforcement learning(RL) theory is presented. The goal is to devise an adaptive guidance algorithm that enables robust, fuel efficient,and accurate landing without the need for off line trajectory generation and real-time tracking. Results from a Monte Carlo simulation campaign show that the algorithm is capable of autonomously following trajectories that are close to the optimal minimum-fuel solutions with an accuracy that surpasses that of past and future Mars missions. The proposed RL-based guidance algorithm exhibits a high degree of flexibility and can easily accommodate autonomous retargeting while maintaining accuracy and fuel efficiency. Although reinforcement learning and other similar machine learning techniques have been previously applied to aerospace guidance and control problems(e.g., autonomous helicopter control), this appears, to the best of the authors knowledge, to be the first application of reinforcement learning to the problem of autonomous planetary landing. | Brian Gaudet Roberto Furfaro | 2014 | IEEE/CAA Journal of Automatica Sinica2014,1,4: | 4 |
| 3 | 青少年甘油磷酸胆碱代谢和心血管病的危险因素:一项队列研究显示文摘甘油磷酸胆碱(glycerophosphocholine,GPC)代谢物可调节动脉粥样硬化,从而导致心血管病风险。临床前期心血管病可能从青春期就开始。研究人员应用靶向血清脂质组学鉴定一组新的GPC,并测试在青春期时这些GPC中的任何一种是否与心血管病传统危险因子,如过量内脏脂肪、升高的血压、胰岛素抵抗和致动脉粥样硬化血脂异常相关。 | Syme C Czajkowski S Shin J Abrahamowicz M Leonard G Perron M Richer L Veillette S Gaudet D Strug L Wang Y Xu H Taylor G Paus T Bennett S Pausova Z 刘莉 叶鹏 | 2016 | 中华高血压杂志2016,24,10: | 3 |
| 4 | Starch Synthesis and Programmed Cell Death during Endosperm Development in Triticale(× Triticosecale Wittmack)显示文摘Triticale(× Triticosecale Wittmack) grains synthesize and accumulate starch as their main energy source.Starch accumulation rate and synthesis activities of ADP-glucose pyrophosphorylase,soluble starch synthases,granule-bound starch synthase and starch-branching enzyme showed similar pattern of unimodal curves during endosperm development.There was no significant difference in activity of the starch granule-bound protein isolated from total and separated starch granules at different developmental stages after anthesis in triticale.Evans Blue staining and analysis of DNA fragmentation indicated that cells of triticale endosperm undergo programmed cell death during its development.Dead cells within the endosperm were detected at 6 d post anthesis(DPA),and evidence of DNA fragmentation was first observed at 21 DPA.The period between initial detection of PCD to its rapid increase overlapped with the key stages of rapid starch accumulation during endosperm development.Cell death occurred stochastically throughout the whole endosperm,meanwhile,the activities of starch biosynthetic enzymes and the starch accumulation rate decreased in the late stages of grain filling.These results suggested that the timing and progression of PCD in triticale endosperm may interfere with starch synthesis and accumulation. | Chun-Yan Li Wei-Hua Li Cheng Li Denis A. Gaudet Andrd Laroche Lian-Pu Cao Zhen-Xiang Lu | 2010 | Journal of Integrative Plant Biology2010,52,7: | 3 |
| 5 | Neurocognitive Performance in Hypertensive Patients after Spine Surgery显示文摘 | Gene T. Yocum John G. Gaudet Lauren A. Teverbaugh Donald O. Quest Paul C. McCormick E Sander Connolly Eric J. Heyer | 2009 | Anesthesiology2009,,2: | 2 |
| 6 | Evaluating landscape health: integrating societal goals and biophysical process显示文摘 | D.J. Rapport C. Gaudet J.R. Karr J.S. Baron C. Bohlen W. Jackson B. Jones R.J. Naiman B. Norton M.M. Pollock | 1998 | Journal of Environmental Management1998,,1: | 2 |
| 7 | Research issues in developing compact pulsed power for high peak power applications on mobile platforms显示文摘 | Gaudet J A Barker R J Buchenauer C J | 2004 | Proceedings of the IEEE2004,92,7: | 1 |
| 8 | Role of tumor necrosis factor alpha gene locus in obesity and obesity associated hypertension in French Canadians显示文摘 | Pausova Z Deslauriers B Gaudet D | 2000 | Hypertension2000,,: | 1 |
| 9 | Role of tumor necrosis factor-alpha gene locus in obesity and obesity-associated hypertension in French Canadians显示文摘 | Deslauriers B Gaudet D | 2000 | Hypertension2000,36,: | 1 |
| 10 | Migration of Cu species in Cu/SAPO-34 during hydrothermal aging显示文摘 | WANG L GAUDET J R WEI L WENG D | 2013 | J Catal2013,306,: | 1 |
| 11 | Pseudohyperaldosteron-ism,liquorice,and hypertension显示文摘 | SontiaB Mooney J Gaudet L | 2008 | J Clin Hypertens(Greenwich)2008,10,2: | 1 |
| 12 | Uniqueness of cournot equilibrium: New results from old methods显示文摘 | Gaudet G Salant S | 1991 | Review of Economic Studies1991,58,: | 1 |
| 13 | Genetic variation in SIPA1 in relation to breast cancer risk and survival after breast cancer diagnosis显示文摘 | Gaudet MM Hunter K Pharoah P | 2009 | Int J Cancer2009,124,7: | 1 |
| 14 | Environmentally induced foregut remodeling by PHA-4 / FoxA and DAF-12 / NHR显示文摘 | AO W GAUDET J KENT W J | 2004 | Science2004,305,: | 1 |
| 15 | Neurocognitive performance in hypertensive patients after spine surgery显示文摘 | Yocum G T Gaudet J G Teverbaugh L A | 2009 | Anes- thesiology2009,110,2: | 1 |
| 16 | Protocols for growth and development of Dictyostelium discoideum 显示文摘 | Petra Fey Anthony S Kowal Pascale Gaudet | 2007 | Nature Protocols2007,2,6: | 1 |
| 17 | Research issues in develop- ing compact pulsed power for high peak power applications on mobile platforms显示文摘 | Gaudet J Barker R Buchenauer C | 2004 | Proceedings of the IEEE2004,92,7: | 1 |
| 18 | Galectin-1 in injured rat spinal cord: implications for macrophage phagocytosis and neural repair显示文摘 | Gaudet AD Sweet DR Polinski NK | 2015 | Mol Cell Neurosci2015,64,: | 1 |
| 19 | Efficacy and safety of ezetimibe coadministered with atorvastatin or simvastatin in patients with homozygous familial hypercholesterolemia显示文摘 | GAGNE C GAUDET D BRUCKERT E | 2002 | Circulation2002,105,21: | 1 |
| 20 | Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury显示文摘 | Gaudet AD Popovich PG Ramer MS | 2011 | J Neureinflammation2011,8,: | 1 |