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| 1 | Big data storage technologies: a survey显示文摘对于容量快速增长、日趋多元化的大数据,业界亟需开发可行性更好的存储工具。为满足大数据存储需求,存储机制已经形成从传统数据管理系统到No SQL技术的结构化转移。然而,目前可用的大数据存储技术无法为持续增长的异构数据提供一致、可扩展和可用的解决方案。在科学实验、医疗保健、社交网络和电子商务等实际应用中,存储是大数据分析的第一步。截至目前,亚马逊、谷歌和阿帕奇等公司形成了大数据存储方案的行业标准,但尚未有关于大数据存储技术性能和容量提升的深入调查和文献报告。本文旨在对目前可用于大数据的最先进的存储技术进行全面调查,提供了一个明确的大数据存储技术分类方法,以帮助数据分析师和研究人员了解和选择更适合其需求的存储机制。我们使用布鲁尔的CAP定理比较和分析了现有存储方法,评估了不同存储架构的性能,讨论了存储技术的意义、应用及其对其他类别数据的支持。为了加快部署可靠和可扩展的存储系统,文中还突出了未来研究面临的几个挑战。 | Aisha SIDDIQA Ahmad KARIM Abdullah GANI | 2017 | Frontiers of Information Technology & Electronic Engineering2017，18，8： | 15 |
| 2 | Role of frailty and sarcopenia in predicting outcomes among patients undergoing gastrointestinal surgery显示文摘According to the United States census bureau 20% of Americans will be older than 65 years in 2030 and half of them will need an operation- equating to about 36 million older surgical patients. Older adults are prone to complications during gastrointestinal cancer treatment and therefore may need to undergo special pretreatment assessments that incorporate frailty and sarcopenia assessments. A focused, structured literature review on Pub Med and Google Scholar was performed to identify primary research articles, review articles, as well as practice guidelines on frailty and sarcopenia among patients undergoing gastrointestinal surgery. The initial search identified 450 articles; after eliminating duplicates, reports that did not include surgical patients, case series, as well as case reports, 42 publications on the impact of frailty and/or sarcopenia on outcome of patients undergoing gastrointestinal surgery were included. Frailty is defined as a clinically recognizable state of increased vulnerability to physiologic stressors resulting from aging. Frailty is associated with a decline in physiologic reserve and function across multiple physiologic systems. Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength. Unlike cachexia, which is typically associated with weight loss due to chemotherapy or a general malignancy-related cachexia syndrome, sarcopenia relates to muscle mass rather than simply weight. As such, while weight reflects nutritional status, sarcopenia- the loss of muscle mass- is a more accurate and quantitative global marker of frailty. While chronologic age is an important element in assessing a patient's peri-operative risk, physiologic age is a more important determinant of outcomes. Geriatric assessment tools are important components of the preoperative work-up and can help identify patients who suffer from frailty. Such data are important, as frailty and sarcopenia have repeatedly been demonstrated among the strongest predictors of both short- and longterm outcome following complicated surgical procedures such as esophageal, gastric, colorectal, and hepatopancreatico-biliary resections. | doris wagner mara mcadams demarco neda amini stefan buttner dorry segev faiz gani timothy m pawlik | 2016 | World Journal of Gastrointestinal Surgery2016，8，1： | 8 |
| 3 | Antithrombotic treatment tailoring and risk score evaluation in elderly patients diagnosed with an acute coronary syndrome显示文摘 | Alexandru Nicolae Mischie Catalina Liliana Andrei Crina Sinescu Gani Bajraktari Eugen Ivan Georgios Nikolaos Chatziathanasiou Michele Schiariti | 2017 | Journal of Geriatric Cardiology2017，14，7： | 5 |
| 4 | Research progress on solid-fueled Scramjet显示文摘The solid-fueled Scramjet is an interesting option for supersonic combustion ramjet.It shows significant advantages such as simple fuel supply and compactness,avoiding the complex system of tanks and pipelines that encountered in liquid-fueled Scramjets.The solid-fueled Scramjet could be the simplest air-breathing engine for the hypersonic flight regime.This paper presents a comprehensive and systematic review of the research progress on solid-fueled Scramjet in various institutes and universities.It summarizes a progress overview of three types of the solid-fueled Scramjet,which covers a wealth of landmark numerical and experimental results.Based on this,several relevant key technologies are proposed.Several inherent scientific issues are refined,such as the mixing mechanism of multi-phase flow and supersonic airflow,ignition and combustion mechanism of the condensed phase in a supersonic airflow,and coupling mechanism of gas and solid phase in a supersonic flow.Finally,the historical development trend is clarified,and some recommendations are provided for future solid-fueled Scramjet. | Xiang ZHAO Zhixun XIA Likun MA Chaolong LI Chuanbo FANG Benveniste NATAN Alon GANY | 2022 | Chinese Journal of Aeronautics2022，35，1： | 4 |
| 5 | Hepatitis B virus subgenotypes and basal core promoter mutations in Indonesia显示文摘AIM:To identify the distribution of hepatitis B virus (HBV) subgenotype and basal core promoter (BCP) mutations among patients with HBV-associated liver disease in Indonesia.METHODS: Patients with chronic hepatitis (CH, n=61), liver cirrhosis (LC, n=62), and hepatocellular carcinoma (HCC,n=48) were included in this study. HBV subgenotype was identified based on S or preS gene sequence, and mutations in the HBx gene including the overlapping BCP region were examined by direct sequencing.RESULTS: HBV genotype B (subgenotypes B2, B3, B4, B5 and B7) the major genotype in the samples, accounted for 75.4%, 71.0% and 75.0% of CH, LC and HCC patients, respectively, while the genotype C (subgenotypes C1, C2 and C3) was detected in 24.6%, 29.0%, and 25.0% of CH, LC, and HCC patients, respectively. Subgenotypes B3 (84.9%) and C1 (82.2%) were the main subgenotype in HBV genotype B and C, respectively. Serotype adw2 (84.9%) and adrq+ (89.4%) were the most prevalent in HBV genotype B and C, respectively. Double mutation (A1762T/G1764A) in the BCP was significantly higher in LC (59.7%) and HCC (54.2%) than in CH (19.7%), suggesting that this mutation was associated with severity of liver disease. The T1753V was also higher in LC (46.8%), but lower in HCC (22.9%) and CH (18.0%), suggesting that this mutation may be an indicator of cirrhosis.CONCLUSION: HBV genotype B/B3 and C/C1 are the major genotypes in Indonesia. Mutations in BCP, such as A1762T/G1764A and T1753V, might have an association with manifestations of liver disease. | Andi Utama Sigit Purwantomo Marlinang Diarta Siburian Rama Dhenni Rino Alvani Gani Irsan Hasan Andri Sanityoso Upik Anderiani Miskad Fardah Akil Irawan Yusuf Wenny Astuti Achwan Soewignjo Soemohardjo Syafruddin AR Lelosutan Ruswhandi Martamala Benyamin Lukito Unggul Budihusodo Laurentius Adrianus Lesmana Ali Sulaiman Susan Tai | 2009 | World Journal of Gastroenterology2009，15，32： | 4 |
| 6 | Association of core promoter mutations of hepatitis B virus and viral load is different in HBeAg(+) and HBeAg(-) patients显示文摘AIM:To identify the prevalence of hepatitis B e antigen (HBeAg) and to assess the association of hepatitis B virus (HBV) core promoter mutations and viral load in Indonesian patients.METHODS:Sixty-four patients with chronic hepatitis,65 with liver cirrhosis and 50 with hepatocellular carcinoma were included in this study.HBeAg and hepatitis B e antibody (HBeAb) tests were performed using enzyme-linked immunosorbent assay and the mutations were analyzed by sequencing.Viral load was measured by real-time polymerase chain reaction.RESULTS:Of 179 patients,108 (60.3%) were HBeAg(-) and 86 (79.6%) of these HBeAg(-) patients had been seroconverted.The A1896 mutation was not found in HBeAg(+) patients,however,this mutation was detected in 70.7% of HBeAg(-) patients.This mutation was frequently found when HBeAg was not expressed (87.7%),compared to that found in HBeAg seroconverted patients (65.1%).The A1899 mutation was also more prevalent in HBeAg(-) than in HBeAg(+) patients (P=0.004).The T1762/A1764 mutation was frequently found in both HBeAg(+) and HBeAg(-) patients,however,the prevalence of this mutation did not significantly differ among the two groups (P=0.054).In HBeAg(+) patients,the T1762/A1764 mutation was correlated with lower HBV DNA (P < 0.001).The A1899 mutation did not correlate with HBV DNA (P=0.609).In HBeAg(-) patients,the T1762/A1764 mutation alone was not correlated with HBV DNA (P=0.095),however,the presence of either the T1762/A1764 or A1896 mutations was associated with increased HBV DNA (P < 0.001).CONCLUSION:The percentage of HBeAg(-) patients is high in Indonesia,and most of the HBeAg(-) patients had been seroconverted.The A1896 mutation was most likely the major cause of HBeAg loss.The T1762/A1764 mutation alone was associated with lower viral loads in HBeAg(+) patients,but not in HBeAg(-) patients. | Andi Utama Marlinang Diarta Siburian Sigit Purwantomo Mariana Destila Bayu Intan Tri Shinta Kurniasih Susan Tai Rino Alvani Gani Laurentius Adrianus Lesmana All Sulaiman Wenny Astuti Achwan Soewignjo Soemohardjo Arnelis Nasrul Zubir Julius Syafruddin AR Lelosutan Benyamin Lukito Tantoro Harmono | 2011 | World Journal of Gastroenterology2011，17，6： | 3 |
| 7 | Hepatoprotective and Antioxidant Activity of Rhizome of Podophyllum hexandrum against Carbon Tetra Chloride Induced Hepatotoxicity in Rats显示文摘Objective To test possible antioxidant activity of n-hexane extract of Podophyllum hexandrum under in vitro and in vivo conditions. Methods The in vitro antioxidant activity was evaluated by the ability of the extract to interact with the stable free radical DPPH, Superoxide (O2-), Hydroxyl (OH-), Hydrogen peroxide (H2O2) radicals, and reducing power ability of the extract was also evaluated. Under in vivo conditions the extract was evaluated for its hepatoprotective activity by measuring different biochemical parameters, such as serum alanine aminotransaminase, serum aspartate aminotransaminase and serum lactate dehydrogenase and antioxidant enzymes. Antioxidant status was estimated by determining the activities of antioxidative enzymes, glutathione reductase (GR), glutathione peroxidase (GPx), glutathione-S-transferase (GST) and superoxide dismutase (SOD), and by determining the levels of reduced glutathione (GSH) and thiobarbituric acid reactive substances (TBARS). Results Hexane extract of P. hexandrum exhibited good radical scavenging capacity in neutralization of DPPH, O2-, OH -, and H2O2 radicals in a dose dependent manner. n-hexane extract of Podophyllum hexandrum at the doses of 20, 30, and 50 mg/kg-day produced hepatoprotective effect by decreasing the activity of serum marker enzymes, while it significantly increased the levels of glutathione (GSH), glutathione peroxidase (GPx), glutathione reductase (GR), super oxide dismutase (SOD), and glutathione-S-transferase (GST) in a dose dependant manner. The effect of n-hexane extract was comparable to that of standard antioxidant vitamin E. Conclusion The extract of Podophyllum hexandrum possess free radical scavenging activity under in vitro conditions and could protect the liver tissue against CCl 4 induced oxidative stress probably by increasing antioxidant defense activities. | Showkat Ahmad GANIE Bilal Ahmad ZARGAR Akbar MASOOD Mohammad Afzal ZARGAR | 2013 | Biomedical and Environmental Sciences2013，26，3： | 3 |
| 8 | A comparison of root characteristics in relation to nutrient and water stress in two maize hybrids显示文摘 | T. Vamerali M. Saccomani S. Bona G. Mosca M. Guarise A. Ganis | 2003 | Plant and Soil2003，，1： | 2 |
| 9 | Association of subclinical hypothyroidism and phenotype, insulin resistance, and lipid parameters in young women with polycystic ovary syndrome显示文摘 | Mohd Ashraf Ganie Bashir Ahmad Laway Tariq Ahmed Wani Mohd Afzal Zargar Sobia Nisar Feroze Ahamed M.L. Khurana Sanjeed Ahmed | 2011 | Fertility and Sterility2011，，6： | 2 |
| 10 | Hybrid Data-Driven and Mechanistic Modeling Approaches for Multiscale Material and Process Design显示文摘The world’s increasing population requires the process industry to produce food,fuels,chemicals,and consumer products in a more efficient and sustainable way.Functional process materials lie at the heart of this challenge.Traditionally,new advanced materials are found empirically or through trial-and-error approaches.As theoretical methods and associated tools are being continuously improved and computer power has reached a high level,it is now efficient and popular to use computational methods to guide material selection and design.Due to the strong interaction between material selection and the operation of the process in which the material is used,it is essential to perform material and process design simultaneously.Despite this significant connection,the solution of the integrated material and process design problem is not easy because multiple models at different scales are usually required.Hybrid modeling provides a promising option to tackle such complex design problems.In hybrid modeling,the material properties,which are computationally expensive to obtain,are described by data-driven models,while the well-known process-related principles are represented by mechanistic models.This article highlights the significance of hybrid modeling in multiscale material and process design.The generic design methodology is first introduced.Six important application areas are then selected:four from the chemical engineering field and two from the energy systems engineering domain.For each selected area,state-ofthe-art work using hybrid modeling for multiscale material and process design is discussed.Concluding remarks are provided at the end,and current limitations and future opportunities are pointed out. | Teng Zhou Rafiqul Gani Kai Sundmacher | 2021 | Engineering2021，7，9： | 2 |
| 11 | Governance and foreign direct investment links: evidence from panel data estimations显示文摘 | Azmat Gani | 2007 | Applied Economics Letters2007，，10： | 2 |
| 12 | Expression of LAG-3 by tumor infiltrating lymphocytes is coincident with the suppression of latent membrane antigen-specific CD8 + T-cell function in Hodgkin lymphoma patients 显示文摘 | GANI)HI MK LAMBLEY E DURAISWAMY J | 2006 | Blood2006，108，7： | 1 |
| 13 | Economic analyses comparing tiotropium with ipralropium or salmeterol in UK patients with COPD显示文摘 | Ray Gani Jane Griffin Steve Kelly Maureen Rutten-van M6lken | 2010 | Primary Care Respiratory Journal2010，19，8： | 1 |
| 14 | Correlations between polyamine analogue-induced increase in spermidine/spermine N1-aeetyltransferase activity,polyamine pool depletion,and growth inhibition in human melanoma cell lines显示文摘 | GANIS B LIBBY P R | 1991 | Cancer Res1991，51，： | 1 |
| 15 | Characteristics of cocombustion of lowrank coal with biomass 显示文摘 | Gani A Morishita K Nishikawa K | 2005 | Energy and Fuels2005，19，4： | 1 |
| 16 | New group contribution method for estimating properties of pure compounds 显示文摘 | Constantinou L Gani R | 1994 | AIChE J1994，40，10： | 1 |
| 17 | Molecular design of solvents for liquid extraction based on UNIFAC显示文摘 | Gani R Brignole E A | 1983 | Fluid Phase Equil1983，13，1： | 1 |
| 18 | Molecular design of solvents for liquid extraction based on UNIFAC 显示文摘 | Gani R Brignole E A | 1983 | Fluid Phase Equilibrium1983，13，： | 1 |
| 19 | An electrophysiological study of scene effects on object identification显示文摘 | Ganis G Kutas M | 2003 | Cognitive Brain Research2003，16，2： | 1 |
| 20 | Investigation of a solid fuel scramjet cumbustor显示文摘 | Ben-Yakar Natan B Gany A | 1998 | Journal of Propulsion and Power1998，14，4： | 1 |
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