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| 1 | 利用声发射法和变形率变化法联合测定地应力显示文摘针对葡萄牙南部Neves-Corvo,SA(Somincor)矿区一垂直钻孔钻取的岩芯,利用声发射法(AE法)和变形率变化法(DRA法)联合测定该区域垂直向地应力。试验表明:矿区垂直向地应力呈现随深度增加而增加的趋势,但由于受褶皱、断裂等多种地质因素的影响,随深度的增加,由AE法和DRA法测得的地应力值差别也越大;通过AE和DRA试验曲线确定地应力在较大程度上依赖于对试验曲线中拐点的判断,而这种判断必须结合曲线本身的特点进行。在同一个试样上同时利用AE法和DRA法测定其地应力不仅是可行的,二者还可相互印证,确保了试验数据的可靠性。 | 谢强 邱鹏 余贤斌 Carlos Dinis da Gama | 2010 | 煤炭学报2010，35，4： | 24 |
| 2 | Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis显示文摘Crohn's disease and ulcerative colitis evolve with a relapsing and remitting course.Determination of inflammatory state is crucial for the assessment of disease activity and for tailoring therapy.However,no simple diagnostic test for monitoring intestinal inflammation is available.Noninvasive markers give only indirect assessments of disease activity.Histopathological or endoscopical examinations accurately assess inflammatory activity,but they are invasive,time consuming and expensive and therefore are unsuitable for routine use.Imaging procedures are not applicable for ulcerative colitis.The usefulness of ultrasound and Doppler imag-ing in assessing disease activity is still a matter of discussion for Crohn's disease,and an increased interest in computed tomography enterograph (CTE) has been seen,mainly because it can delineate the extent and severity of bowel wall inflammation,besides detecting extraluminal findings.Until now,the available data concerning the accuracy of magnetic resonance enterography in detecting disease activity is less than CTE.Due to this,clinical activity indices are still commonly used for both diseases. | Eduardo Garcia Vilela Henrique Osvaldo da Gama Torres Fabiana Paiva Martins Maria de Lourdes de Abreu Ferrari Marcella Menezes Andrade Aloísio Sales da Cunha | 2012 | World Journal of Gastroenterology2012，18，9： | 23 |
| 3 | 细晶花岗岩的声发射特征试验研究显示文摘对葡萄牙细晶花岗岩同一岩样进行多次单轴压缩循环加卸载试验,监测试验过程中岩样的声发射活动,记录岩样的变形特征,分析总结声发射与变形之间的相互关系。试验表明,葡萄牙细晶花岗岩在高应力状态下凯塞效应明显,所受应力越高,凯塞效应越弱;在判断岩石凯塞点时,因时间–累计声发射能量曲线中拐点明显,比利用时间–累计声发射事件数曲线更容易、更合理;另外,了解试样的变形特征对解释声发射试验结果是一个有益的补充。 | 谢强 Carlos Dinis da Gama 余贤斌 | 2008 | 岩土工程学报2008，30，5： | 20 |
| 4 | Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame显示文摘导致的 pluripotent 的产生从体的细胞的茎(iPS ) 细胞被定义 reprogramming 抄写因素(TF ) 的同时的病毒的 transduction 成功地完成了。然而,这个过程为基因交货要求多重病毒的向量。作为结果,产生了 iPS 房间港口在他们的染色体的众多的病毒的集成地点。这能增加基因 mutagenesis 和 genomic 不稳定性的概率,并且介绍重要障碍给研究和 iPS 房间的临床的申请研究。在这篇论文,我们在场定义因素是的一个简单 lentivirus reprogramming 在系统经由自我劈开的 2A 序列熔化了在里面框架进一个单个开的读物框架(ORF ) 。一个 GFP 标记下游地被放 transgene 启用 transgene 表示追踪。我们证明这个 polycistronic 表示系统高效地产生 iPS 房间。产生 iPS 房间有正常 karyotypes 并且类似于鼠标在形态学和基因表示的胚胎的干细胞。而且,他们能在 vitro 并且在 vivo 试金在两个区分进三胚胎的细菌层的房间类型。显著地,大多数这些 iPS 房间仅仅怀有病毒的向量的一个单个拷贝。这个系统提供一个珍贵工具因为 iPS 房间的产生,和我们的数据建议在每个房间的 transduced reprogramming TF 的表示的平衡为 reprogramming 进程是必要的。更重要地,当由非集成的基因交货系统交付了时,这重新设计的单个 ORF 将没有基因修正便于人的 iPS 房间的有效产生。 | Lijian Shao Wei Feng Yan Sun Hao Bai Jun Liu Caroline Currie Jaejung Kim Rafael Gama Zack Wang Zhijian Qian Lucy Liaw Wen-Shu Wu | 2009 | Cell Research2009，19，3： | 12 |
| 5 | 时间延迟对劈裂试验条件下岩石凯塞效应的影响显示文摘验证了粗晶花岗岩在劈裂试验条件下凯塞效应的存在性。进行了循环加卸载时间间隔分别为2、15d和45d时岩石的声发射试验,讨论了时间延迟对花岗岩凯塞效应的影响。研究结果表明,前期荷载越接近极限强度,岩石的凯塞效应越不明显;凯塞效应随再次加载时间延迟的增加而削弱,在对花岗岩的声发射试验中观察到15d以后岩石的凯塞效应仍然很显著,45d后凯塞效应基本消失。文中同时对试件与加载设备之间的接触状态对声发射试验结果的影响作了初步的定性分析。 | 谢强 余贤斌 Carlos Dinis da Gama | 2010 | 岩土力学2010，31，1： | 9 |
| 6 | Comparative stability analyses of traditional and selective room-and-pillar mining techniques for sub-horizontal tungsten veins显示文摘The stability and productivity concerning a modification on the traditional room and pillar for a new selective technique at the Portuguese Panasqueira Mine have been described.The traditional room-and-pillar stoping uses 5.0-m wide rooms with 3.0 m×3.0 m pillars,while the selective room-and-pillar mining technique consists in stoping with rooms of 4.0 m wide and pillars of 4 m×4 m with a subsequent selective cutting of the quartz veins at the mid pillar of approximately 0.5 m high,to obtain a pillar section with an area of 3.0 m×3.0 m.The stability and productivity analyses indicate that the selective technique obtains smaller average pillar safety factor,more rock mass displacement,more extraction and selectivity ratios,and ore grade improvement,compared with the traditional technique.These results show that the selective technique is also more convenient.This proposed selective room-and-pillar mining technique is applicable to any sub-horizontal narrow quartz veins with wolfram,gold,etc.such as the famous La Rinconada gold mine in the Peruvian Andes. | Vidal Felix Navarro Torres Carlos Dinis da Gama Matilde Costa e Silva Paula Falcao Neves Qiang Xie | 2011 | International Journal of Minerals,Metallurgy and Materials2011，18，1： | 7 |
| 7 | 加载方向变化对细晶花岗岩凯塞效应的影响显示文摘进行了单轴压缩试验条件下重复加载时加载方向变化对细晶花岗岩凯塞效应的影响试验研究。试验发现,加载方向不变或加载角度变为7°时,岩石的凯塞效应明显;加载角度为10°和15°时,部分试件由于受试验环境、试件加工等因素的影响观测不到凯塞效应。试验统计数据表明,重复加载时加载方向变化越大,其凯塞效应越弱。研究同时发现:加载方向变化对凯塞效应的影响还取决于岩石的受力状态,单轴压缩状态下,岩石受力状态单一,重复加载时加载方向的轻微变化不会影响岩石对历史应力的记忆能力;劈裂状态下,圆盘试样应力状态复杂,加载方向的轻微变化足以引起试样内应力的重分布,进而影响岩石的凯塞效应。 | 谢强 江小城 余贤斌 Carlos inis da Gama | 2010 | 煤炭学报2010，35，10： | 6 |
| 8 | 神经网络-交互验证方法及其矿业应用显示文摘针对现有矿业神经网络预测方法存在的不足,提出了神经网络交互验证建模方法。 | 李英龙 C.Dinis Da Gama | 1999 | 金属矿山1999，28，5： | 6 |
| 9 | Toxicity studies for indigenous Bacillus thuringiensis isolates from Malang city,East Java on Aedes aegypti larvae显示文摘Objective:To investigate the toxicity of indigenous Bacillus thuringiensis(B.thuringiensis)isolates from Malang City for controlling Aedes aegypti(Ae.aegypti)larvae.Methods:Soil samples were taken from Purwantoro and Sawojajar sub-districts.Bacterial isolation was performed using B.thuringiensis selective media.Phenotypic characteristics of the isolates were obtained with the simple matching method.The growth and prevalence of spores were determined by the Total Plate Count method,and toxicity tests were also performed on the third instar larval stage of Ae.aegypti.The percentage of larval mortality was analysed using probit regression.The LC50was analysed by ANOVA,and the Tukey HSD interval was 95%.Results:Among the 33 selected bacterial isolates,six were obtained(PWR4-31,PWR4-32,SWJ4-2b,SWJ4-4b,SWJ-4k and SWJ5-1)that had a similar phenotype to reference B.thuringiensis.Based on the dendrogram,all of the bacterial isolates were 71%similar.Three isolates that had a higher prevalence of reference B.thuringiensis were PWR4-32,SWJ4-4b and SW5-1,of which the spore prevalence was 52.44%,23.59%,34.46%,respectively.These three indigenous isolates from Malang City successfully killed Ae.aegypti larvae.The PWR4-32 isolates were the most effective at killing the larvae.Conclusions:Six indigenous B.thuringiensis isolates among the 33 bacterial isolates found in the Sawojajar and Purwantoro sub-districts were toxic to the third instar larvae of Ae.aegypti.The PWR4-32 isolates were identical to tbe reference B.thuringiensis and had 88%phenotype similarity.The PWR4-32 isolates had the highest spore prevalence(52.44%),and the early stationary phase occurred at 36 h.The PWR4-32 isolates were the most effective at killing Ae.aegypti larvae(LC50-72 h=2.3×108 cells/mL). | Zulfaidah Penata Gama Nobukazu Nakagoshi Suharjono Faridah Setyowati | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，2： | 2 |
| 10 | Acute hepatitis after amiodarone infusion显示文摘Acute hepatitis is a very rare, but potentially fatal, adverse effect of intravenous amiodarone. We present a case of an 88-year-old man with history of ischemic dilated cardiomyopathy and severely depressed left ventricular function that was admitted to our coronary care unit with diagnosis of decompensated heart failure and non-sustained ventricular tachycardia. A few hours after the beginning of intravenous amiodarone he developed an acute hepatitis. There was a completely recovery within the next days after amiodarone withdrawn and other causes of acute hepatitis have been ruled out. This case highlights the need for close monitoring of hepatic function during amiodarone infusion in order to identify any potential hepatotoxicity and prevent a fatal outcome. Oral amiodarone is, apparently, a safe option in these patients. | Paulo Fonseca Adelaide Dias Helena Gonçalves Aníbal Albuquerque Vasco Gama | 2015 | World Journal of Clinical Cases2015，3，10： | 2 |
| 11 | 头颈癌患者的体质指数和预后显示文摘体质指数(BMI)与头颈癌结局相关性差异显著。该文旨在评估BMI与诊断或早期成人头颈癌结果之间的相关性。纳入研究的样本为加拿大多伦多玛格丽特王子肿瘤中心头颈鳞癌患者,检测指标包括烟草和酒精的使用、病情状态、并发症及BMI指数。 | Gama RR Song Y Zhang Q 张凌 | 2017 | 中国口腔颌面外科杂志2017，15，3： | 2 |
| 12 | De novo intraocular amyloid deposition after hepatic transplantation in familial amyloidotic polyneuropathy显示文摘The familiar amyloid polyneuropathy(FAP) is a rare autosomal-dominant systemic amyloidosis. Amyloid deposition occurs more frequently and extensively in the vitq. The increase in intraocular pressure(IOP) is a result of deposition of transthyretin(TTR) in trabecular meshwork. Rarely, the amyloid deposition in anterior segment can be more exuberant than in posterior segment. A 42 years old man, with FAP(Val30Met mutation), liver transplantation in 1997. He was asymptomatic, without any significant ocular abnormality until 2011. In 2011 he had an episode of pain in right eye(RE). Scalloped pupils, pupillary amyloid deposits and subtle vitreous opacities were detected. The IOP was 40 mmHg in RE and 28 mmHg in left eye(LE) with open angle. Optical coherence tomography detected a temporal superior retinal nerve fiber layer defect in LE and perimetry was normal. Topical timolol was initiated, and brimonidine was subsequently added to improve IOP control, which was achieved with topical medication until last evaluation. No progression occurred since 2011. Actually, with longer life expectancies, there is an increased risk of ocular involvement in FAP, even after liver transplantation. Although rare, a more exuberant amyloid deposition in anterior segment vs posterior segment can occur, and supports an important role of amyloid production in ciliary pigment epithelium in these patients. Medical control of IOP and a stable course are unusual in this secondary glaucoma. Ophthalmologists have an important task in the follow-up of patients and early diagnosis of risk factors for secondary glaucoma, such as scalloped pupils with amyloid deposits. | Ivo Filipe Gama Leonor Duarte Almeida | 2017 | World Journal of Transplantation2017，7，4： | 2 |
| 13 | Identification of molecular phenotypes in canine mammary carcinomas with clinical irnplications: application of the human classification 显示文摘 | Gama A Alves A Schmitt F | 2008 | Virchows Arch2008，453，： | 1 |
| 14 | Anesthesia in pa-tients with chronic obstructive pulmonary diseases显示文摘 | Spieth PM Güldner A Gama de Abreu M | 2010 | Anaesthesist2010，59，1： | 1 |
| 15 | Hippocampal abnormalities in an MR imaging series of patients with tuberous sclerosis显示文摘 | Gama HP da Rocha AJ Valerio RM | 2010 | AJNR Am J Neuroradiol2010，31，6： | 1 |
| 16 | A Comparison of Oven-cured and Induction-cured Adhesively Bonded Composite Joints显示文摘 | Mahdi S Kim H J Gama B A | 2003 | Journal of Composite Materials2003，37，6： | 1 |
| 17 | Magnetic properties of nanocrystalline Ni-Zn ferrites doped with samarium显示文摘 | Gama L Diniz A P Costa A C F M | 2006 | Physica B2006，384，12： | 1 |
| 18 | Effects of trans- 10, cis-12 conjugated linoleic acid on gene expression and lipid metabolism of adipose tissue of growing pigs显示文摘 | Jose A A Gama M A Lanna D D | 2008 | Genet Mol Res2008，7，2： | 1 |
| 19 | Learning with drift detection显示文摘 | Gama J Medas P Castillo G | 2004 | SBIA Brazilian Symposium on Artificial Intelligence2004，3171，17： | 1 |
| 20 | Naturalistic pharmacogenetic study of treatment resistance to typical neuroleptics in European–Brazilian schizophrenics显示文摘 | Fabiana B. Kohlrausch Clarissa S. Gama Maria Inês Lobato Paulo Belmonte-de-Abreu Sidia M. Callegari-Jacques Alejandro Gesteira Francisco Barros ángel Carracedo Mara H. Hutz | 2008 | Pharmacogenetics and Genomics2008，，7： | 1 |
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