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| 1 | Rectal cancer: An evidence-based update for primary care providers显示文摘Rectal adenocarcinoma is an important cause of cancer-related deaths worldwide, and key anatomic differences between the rectum and the colon have significant implications for management of rectal cancer. Many advances have been made in the diagnosis and management of rectal cancer. These include clinical staging with imaging studies such as endorectal ultrasound and pelvic magnetic resonance imaging, operative approaches such as transanal endoscopic microsurgery and laparoscopic and robotic assisted proctectomy, as well as refined neoadjuvant and adjuvant therapies. For stage Ⅱ and Ⅲ rectal cancers, combined chemoradiotherapy offers the lowest rates of local and distant relapse, and is delivered neoadjuvantly to improve tolerability and optimize surgical outcomes, particularly when sphincter-sparing surgery is an endpoint. The goal in rectal cancer treatment is to optimize diseasefree and overall survival while minimizing the risk of local recurrence and toxicity from both radiation and systemic therapy. Optimal patient outcomes depend on multidisciplinary involvement for tailored therapy. The successful management of rectal cancer requires a multidisciplinary approach, with the involvement of enterostomal nurses, gastroenterologists, medical and radiation oncologists, radiologists, pathologists and surgeons. The identification of patients who are candidates for combined modality treatment is particularly useful to optimize outcomes. This article provides an overview of the diagnosis, staging and multimodal therapy of patients with rectal cancer for primary care providers. | Wolfgang B Gaertner Mary R Kwaan Robert D Madoff Genevieve B Melton | 2015 | World Journal of Gastroenterology2015，21，25： | 13 |
| 2 | Load-related bonemodelling at the interface of orthodontic micro-implants显示文摘 | Büchter A Wiechmann D Gaertner C | 2006 | ClinOral Implants Res2006，17，6： | 1 |
| 3 | Drifting fish aggregation devices could act as an ecological trap for tropical tuna species显示文摘 | Hallier J P Gaertner D | | 0，，： | 1 |
| 4 | Pulmonary endothelium as a site of synthesis and storage of interleukin-6 in experimental congestive heart failure显示文摘 | GAERTNER R LEPAILLEUR-ENOUF D GONZALEZ W | 2003 | Eur J Heart Fail2003，5，4： | 1 |
| 5 | Effects of the gear deployment strategy and current shear on pelagic longline shoaling 显示文摘 | BACH P GAERTNER D MENKES C | 2009 | Fisheries Research2009，95，1： | 1 |
| 6 | Life-limiting mechanisms in Ba- oxide, Ba-dispenser and Ba-Scandate cathode 显示文摘 | Gaertner G Barratt D | 2005 | Ap- plied Surface Science2005，251，1： | 1 |
| 7 | Pulmonary endothelium as a site of synthesis and storage of interleukin-6 in experimental congestive heart failure显示文摘 | Gaertner R Lepailleur-Enouf D Gonzalez W | 2003 | Eur Heart Fail2003，5，4： | 1 |
| 8 | Environment, Strategy, and the Implementa- tion of Administrative Change: The Case of Civil Service Reform显示文摘 | GAERTNER G H GAERTNER K N AKINNUSI D M | 1984 | Academy of Management Jour na11984，27，3： | 1 |
| 9 | Pulmonary endothelium as a site of synthesis and storage of interleukin-6 in experimental congestive heart failure显示文摘 | Gaertner R Lepailleur-Enouf D Gonzalez W | 2003 | Eur J Heart Fail2003，5，4： | 1 |
| 10 | Pulmonary and mediastinal glomus tumors report of five cases including a pulmonary glomangiosarcoma:aclinico pathologic study with literature review显示文摘 | Gaertner E M Steinberg D M Huber M | 2000 | Am J Surg Pathol2000，24，8： | 1 |
| 11 | Drifting fish aggregation devices could act as an ecological trap for tropical tuna species显示文摘 | HALLIER J GAERTNER D | 2008 | Marine Ecology Progress Series2008，353，： | 1 |
| 12 | Catalytic coupling of carboxylic acids by ketonization as a processing step in biomass conversion显示文摘 | Gaertner C A Serrano-Ruiz J C Braden D J | 2009 | J Catal2009，266，1： | 1 |
| 13 | Hundred years:anniversary of the oxide cathode-A historical review显示文摘 | Gaertner G den Engelsen D | 2005 | Applied Surface Science2005，251，14： | 1 |
| 14 | Observed changes in the species composition of tuna schools in the Gulf of Guinea between 1981 and 1999, in relation with the Fish Aggregating Devices fishery显示文摘 | Fontenean A Ariz J Gaertner D | 2000 | Aquat Living Resour2000，13，4： | 1 |
| 15 | 6SGa-Labeled anti-prostate-specific membrane antigen peptide as marker for aildrogen deprivation therapy response in prostate cancer 显示文摘 | SCHLENKHOFF C D GAERTNER F ESSLER M et al | 2016 | Clin Nucl Med2016，41，5： | 1 |
| 16 | Fishing activity of tuna purse seiners estimated from vessel monitoring system (VMS) data 显示文摘 | Bez N Walker E Gaertner D | 2011 | Canadian Journal of Fisheries and Aquatic Sciences2011，68，11： | 1 |
| 17 | Transglutaminase-catalyzed incorporation of lysine oligomers into casein显示文摘 | Bercovici D Gaertner H F Puigserver A J | 2002 | Journal of Agricultural and Food Chemistry2002，35，3： | 1 |
| 18 | Drifting fish aggregation devices could act as an ecological trap for tropical tuna species显示文摘 | Hallier J P Gaertner D | 2008 | Mar Ecol Prog Ser2008，353，： | 1 |
| 19 | Pulmonary and mediastinal glomus tumors--report of five cases including a pulmonary glomangiosarcoma: a clinicopathologic study with literature review显示文摘 | Gaertner E M Steinberg D M Huber M | 2000 | Am J Surg Pathol2000，24，8： | 1 |
| 20 | Real-time DNA sequencing from single polymerase molecules显示文摘 | Eid J Fehr A Gray J Luong K Lyle J Otto G Peluso P Rank D Baybayan P Bettman B Bibillo A Bjornson K Chaudhuri B Christians F Cicero R Clark S Dalal R Dewinter A Dixon J Foquet M Gaertner A Hardenbol P Heiner C Hester K Holden D Kearns G Kong X Kuse R Lacr | | 0，，5910： | 1 |
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