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| 1 | Rectal cancer: An evidence-based update for primary care providers显示文摘Rectal adenocarcinoma is an important cause of cancer-related deaths worldwide, and key anatomic differences between the rectum and the colon have significant implications for management of rectal cancer. Many advances have been made in the diagnosis and management of rectal cancer. These include clinical staging with imaging studies such as endorectal ultrasound and pelvic magnetic resonance imaging, operative approaches such as transanal endoscopic microsurgery and laparoscopic and robotic assisted proctectomy, as well as refined neoadjuvant and adjuvant therapies. For stage Ⅱ and Ⅲ rectal cancers, combined chemoradiotherapy offers the lowest rates of local and distant relapse, and is delivered neoadjuvantly to improve tolerability and optimize surgical outcomes, particularly when sphincter-sparing surgery is an endpoint. The goal in rectal cancer treatment is to optimize diseasefree and overall survival while minimizing the risk of local recurrence and toxicity from both radiation and systemic therapy. Optimal patient outcomes depend on multidisciplinary involvement for tailored therapy. The successful management of rectal cancer requires a multidisciplinary approach, with the involvement of enterostomal nurses, gastroenterologists, medical and radiation oncologists, radiologists, pathologists and surgeons. The identification of patients who are candidates for combined modality treatment is particularly useful to optimize outcomes. This article provides an overview of the diagnosis, staging and multimodal therapy of patients with rectal cancer for primary care providers. | Wolfgang B Gaertner Mary R Kwaan Robert D Madoff Genevieve B Melton | 2015 | World Journal of Gastroenterology2015，21，25： | 13 |
| 2 | A meta - analysis ofantecedents and correlates of employee turnover: Update, moderatortests,and research implications for the millennium 显示文摘 | GRIFFETH R W HOM P W GAERTNER S | 2000 | Journal ofManagement2000，26，3： | 1 |
| 3 | A meta-analysis of antecedents and correlates of emplotee turnover: update, moderator test, and research implications for the next millennium显示文摘 | Griffeth R W Hom P W Gaertner S | 2000 | Journal of Management2000，26，： | 1 |
| 4 | A Meta-analysis of Antecedents and Correlates of Employee Turnover : Update, Modera- tor Tests, and Research Implications for the Next Millennium显示文摘 | Griffeth R W Hom P W Gaertner S | 2000 | Journal of management2000，26，3： | 1 |
| 5 | Pulmonary endothelium as a site of synthesis and storage of interleukin-6 in experimental congestive heart failure显示文摘 | GAERTNER R LEPAILLEUR-ENOUF D GONZALEZ W | 2003 | Eur J Heart Fail2003，5，4： | 1 |
| 6 | Cyclic plasm IL- 6 levels during normal menstrual cycle显示文摘 | Angstwurm MW Gaertner R Ziegler- Heitbrock HW | 1997 | Cytokine1997，9，5： | 1 |
| 7 | Outcome in elderly patients with severe infection is influenced by sex hormones but not gender显示文摘 | Angstwurm MW Gaertner R Schopohl J | 2005 | Crit Care Med2005，33，12： | 1 |
| 8 | A meta-analysis of antecedents and correlates of employee turnover: Update, moderator tests, and research implications for the next millennium 显示文摘 | Griffeth R W Horn P W Gaertner S | 2000 | Journal of Management2000，26，3： | 1 |
| 9 | Photographic Study of Nucleate Pool Boiling on a Horizontal Surface显示文摘 | Gaertner R F | 1965 | Trans ASME J Heat Transfer1965，87，： | 1 |
| 10 | Photographic study of nucleate pool boiling on a horizontal surface显示文摘 | Gaertner R F | 1965 | Journal of Heat Transfer1965，，87： | 1 |
| 11 | Integration of the Kohonen's Self-organising Map and K-means Algorithm for the Segmenta- tion of the AE Data Collected during Tensile Tests on Cross-ply Composites显示文摘 | Godin N Huguet S Gaertner R | 2005 | NDT&International2005，38，： | 1 |
| 12 | Use of acoustic emission to identify damage modes in glass fibre reinforced polyester显示文摘 | Huguet S Godin N Gaertner R | 2002 | Composites Science and Technology2002，62，1011： | 1 |
| 13 | Finite element modeling of the actual structure of cellular materials determined by X-ray tomography显示文摘 | Youssef S Maire E Gaertner R | 2005 | Acta Materialia2005，53，： | 1 |
| 14 | A Meta-Analysis of Ante- cedents and Correlates of Employee Turnover: Update,Moder- ator Tests, and Research Implications for the Next Millennium 显示文摘 | Griffeth R W Horn P W Gaertner S | 2000 | Journal of Management2000，26，3： | 1 |
| 15 | Pulmonary endothelium as a site of synthesis and storage of interleukin-6 in experimental congestive heart failure显示文摘 | Gaertner R Lepailleur-Enouf D Gonzalez W | 2003 | Eur Heart Fail2003，5，4： | 1 |
| 16 | A meta-analysis of antecedents and correlates of employee turnover:update,moderator tests,and research implications for the next millennium显示文摘 | GRIFFETH R W HOM P W GAERTNER S | | 0，，03： | 1 |
| 17 | Pulmonary endothelium as a site of synthesis and storage of interleukin-6 in experimental congestive heart failure显示文摘 | Gaertner R Lepailleur-Enouf D Gonzalez W | 2003 | Eur J Heart Fail2003，5，4： | 1 |
| 18 | A meta - analysis of anteced- ents and correlates of employee turnover: Update, moderator tests, and research implications for the next millennium 显示文摘 | Griffeth R W Hom P W Gaertner S | 2000 | Journal of Manage- ment2000，26，3： | 1 |
| 19 | Site-specific attachment of functionalized poly (ethylene glycol) to the amino terminus of proteins显示文摘 | Gaertner H F Offord R E | 1996 | Bioconjug Chem1996，7，1： | 1 |
| 20 | A meta-analysis of antecedents and correlates of employee turnover : Update, moderator tests, and research implications for the next millennium 显示文摘 | Griffeth R W Hom P W Gaertner S | 2000 | Journal of Management2000，26，3： | 1 |
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