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| 1 | Reservoir Porosity Measurement Uncertainty and its Influence on Shale Gas Resource Assessment显示文摘Reservoir porosity is a critical parameter for the process of unconventional oil and gas resources assessment. It is difficult to determine the porosity of a gas shale reservoir, and any large deviation will directly reduce the credibility of any shale gas resources evaluation. However, there is no quantitative explanation for the accuracy of porosity measurement. In this paper, measurement uncertainty, an internationally recognized index, was used to evaluate the results of porosity measurement of gas shale plugs, and its impact on the credibility of shale gas resources assessment was determined. The following conclusions are drawn:(1) the measurement uncertainty of porosity of a shale plug is 1.76%–3.12% using current measurement methods, the upper end of which is too large to be acceptable. It is suggested that the measurement uncertainty should be factored into the standard helium gas injection porosity determination experiment, and the uncertainty should be less than 2.00% when using a high-precision pressure gauge;(2) in order to reduce the risk for exploration and decision-making, attention should be paid to the large uncertainty(30% at least) of shale gas resource assessment results, sometimes with corrections being made based on the practical considerations;(3) a pressure gauge with an accuracy of 0.25% of the full scal cannot meet the requirements of porosity measurement, and a high-precision plug cutting method or high-precision bulk volume measurement method such as one using 3 D scanning, is recommended to effectively reduce porosity uncertainty;(4) the method and process for evaluating the measurement uncertainty of gas shale porosity could also be referred for assessment of experimental quality by other laboratories. | TIAN Hua ZOU Caineng LIU Shaobo HONG Feng FAN Junjia GUI Lili HAO Jiaqing | 2020 | Acta Geologica Sinica(English Edition)2020，94，2： | 2 |
| 2 | Characteristics,origin and controlling effects on hydrocarbon accumulation of overpressure in foreland thrust belt of southern margin of Junggar Basin,NW China显示文摘Aiming at the differential distribution of overpressure in vertical and lateral directions in the foreland thrust belt in the southern margin of Junggar Basin,the study on overpressure origin identification and overpressure evolution simulation is carried out.Based on the measured formation pressure,drilling fluid density and well logging data,overpressure origin identification and overpressure evolution simulation techniques are used to analyze the vertical and lateral distribution patterns of overpressure,genetic mechanisms of overpressure in different structural belts and causes of the differential distribution of overpressure,and the controlling effects of overpressure development and evolution on the formation and distribution of oil and gas reservoirs.The research shows that overpressure occurs in multiple formations vertically in the southern Junggar foreland thrust belt,the deeper the formation,the bigger the scale of the overpressure is.Laterally,overpressure is least developed in the mountain front belt,most developed in the fold anticline belt,and relatively developed in the slope belt.The differential distribution of overpressure is mainly controlled by the differences in disequilibrium compaction and tectonic compression strengths of different belts.The vertical overpressure transmission caused by faults connecting the deep overpressured system has an important contribution to the further increase of the overpressure strength in this area.The controlling effect of overpressure development and evolution on hydrocarbon accumulation and distribution shows in the following aspects:When the strong overpressure was formed before reservoir becoming tight overpressure maintains the physical properties of deep reservoirs to some extent,expanding the exploration depth of deep reservoirs;reservoirs below the overpressured mudstone cap rocks of the Paleogene Anjihaihe Formation and Lower Cretaceous Tugulu Group are main sites for oil and gas accumulation;under the background of overall overpressure,both overpressure strength too high or too low are not conducive to hydrocarbon enrichment and preservation,and the pressure coefficient between 1.6 and 2.1 is the best. | LU Xuesong ZHAO Mengjun ZHANG Fengqi GUI Lili LIU Gang ZHUO Qingong CHEN Zhuxin | 2022 | Petroleum Exploration and Development2022，49，5： | 2 |
| 3 | In situ apolipoprotein E-enriched corona guides dihydroartemisinin-decorating nanoparticles towards LDLr-mediated tumor-homing chemotherapy显示文摘The therapeutic efficiency of active targeting nanoparticulate drug delivery systems(nano-DDS)is highly compromised by the plasma proteins adsorption on nanoparticles(NPs)surface,which significantly hinders cell membrane receptors to recognize the designed ligands,and provokes the off-target toxicity and rapid clearance of NPs in vivo.Herein,we report a novel dihydroartemisinin(DHA)-decorating nano-DDS that in situ specifically recruits endogenous apolipoprotein E(apoE)on the NPs surface.The apoE-anchored corona is able to prolong PLGA-PEG2000-DHA(PPD)NPs circulation capability in blood,facilitate NPs accumulating in tumor cells by the passive enhanced permeability and retention(EPR)effect and low-density lipoprotein receptor(LDLr)-mediated target transport,and ultimately improve the in vivo antitumor activity.Our findings demonstrate that the strategy of in situ regulated apoE-enriched corona ensures NPs an efficient LDLr-mediated tumor-homing chemotherapy. | Zhenbao Li Jiaojiao Zhu Yongqi Wang Mei Zhou Dan Li Shunzhe Zheng LiLi Yin Cong Luo Huicong Zhang Lu Zhong Wei Li JianWang Shuangying Gui Biao Cai Yongjun Wang Jin Sun | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，4： | 1 |
| 4 | Improvement of in situ LA-ICP-MS U-Pb dating method for carbonate minerals and its application in petroleum geology显示文摘In situ carbonate U-Pb dating is gaining popularity,and it has great potential for application in petroleum geology.However,the low U content(<10μg/g)and high common Pb content of carbonate minerals,along with the uneven distribution of U and Pb and the lack of matrix-matched reference material make carbonate U-Pb dating inaccurate and less successful,which limits the widespread application in geosciences.This study evaluated the limitations of in situ carbonate U-Pb dating and proposed a method to rationally determine the laser ablation parameters of samples by improving the experimental approach based on the laser ablation sector field inductively coupled plasma mass spectrometry(LA-SF-ICP-MS).By setting a different spot size and laser frequency for the reference material and unknown samples in the same session based on the U content of the sample,the ablation craters of the reference material and unknown samples were given the same depth/width ratio,avoiding systematic offset caused by differences in down-hole element fractionation and reducing the consume of reference material.Depending on the heterogeneous distribution of U and Pb contents in carbonate minerals,the method of grid screening and setting ablation spots during screening were used to quickly select domains with high U and low common Pb,which improves the efficiency of setting laser spots and the success rate of dating,as well as reduces the experimental time and economic cost.The accuracy and success rate of carbonate U-Pb dating were effectively improved by improving the experimental method,and the technique was applied to two carbonate samples with low U and high common Pb contents that were difficult to date by traditional methods.The two samples are the saddle dolomite in the central Sichuan Basin and the calcite cement in the sandstone reservoir of the Cretaceous Qingshuihe Formation in the South Junggar Basin.The robust ages have been obtained,which constrains the timing of the diagenetic and hydrocarbon accumulation process in the studied area. | Xuesong Lu Lili GUI Weiyan CHEN Shaobo LIU Shitou WU Junjia FAN Qiang LIU Jing SUN Liangliang ZHANG Yang XIAO Wenxia YANG Rizhou CAO | 2023 | Science China Earth Sciences2023，66，12： | 1 |
| 5 | Innovative fluorescence spectroscopic techniques for rapidly characterising oil inclusions显示文摘 | Liu Keyu George SC Lu Xuesong Gong Se Tian Hua Gui Lili | 2014 | Organic Geochemistry2014，72，： | 1 |
| 6 | Near‐Equilibrium Chemical Vapor Deposition of High‐Quality Single‐Crystal Graphene Directly on Various Dielectric Substrates显示文摘 | Jianyi Chen Yunlong Guo Lili Jiang Zhiping Xu Liping Huang Yunzhou Xue Dechao Geng Bin Wu Wenping Hu Gui Yu Yunqi Liu | 2014 | Adv. Mater2014，，9： | 1 |
| 7 | Dynamic phosphorylation of CENP-N by CDK1 guides accurate chromosome segregation in mitosis显示文摘In mitosis,accurate chromosome segregation depends on the kinetochore,a supermolecular machinery that couples dynamic spin-dle microtubules to centromeric chromatin.However,the structure–activity relationship of the constitutive centromere-associated network(CCAN)during mitosis remains uncharacterized.Building on our recent cryo-electron microscopic analyses of human CCAN structure,we investigated how dynamic phosphorylation of human CENP-N regulates accurate chromosome segregation.Our mass spectrometric analyses revealed mitotic phosphorylation of CENP-N by CDK1,which modulates the CENP-L–CENP-N interaction for accurate chromosome segregation and CCAN organization.Perturbation of CENP-N phosphorylation is shown to prevent proper chromosome alignment and activate the spindle assembly checkpoint.These analyses provide mechanistic insight into a previously undefined link between the centromere–kinetochore network and accurate chromosome segregation. | Ran Liu Zhen Dou Tian Tian Xinjiao Gao Lili Chen Xiao Yuan Chunyue Wang Jiahe Hao Ping Gui McKay Mullen Felix Aikhionbare Liwen Niu Guoqiang Bi Peng Zou Xuan Zhang Chuanhai Fu Xuebiao Yao Jianye Zang Xing Liu | 2023 | Journal of Molecular Cell Biology2023，15，6： | 0 |
| 8 | Petrological evidence of kaolinite transformation to dawsonite显示文摘Clay minerals,especially authigene kaolinite,are abundant in the dawsonite-bearing sandstone from the Gudian and Qian'an regions in the southern Songliao Basin. The relationship between dawsonite and kaolinite has been investigated based on drilling data from 50 wells in the Jilin Oil Field and petrological characteristics analyses on 23 core samples from the Gudian and Qian'an regions. The study revealed a negative relationship between the content of dawsonite and kaolinite,suggesting that kaolinite was replaced by the dawsonite. Combined with thermodynamics and geochemical analysis published previously,it is concluded that kaolinite is unstable under CO2 -rich environments and can transform into dawsonite. | GUI Lily LIU Li YU Miao LIU Na YANG Huidong ZHANG Yongmei | 2012 | Global Geology2012，15，2： | 0 |
| 9 | Restoration of reservoir diagenesis and hydrocarbon accumulation process by calcite in-situ U-Pb dating and fluid inclusion analysis: A case study on Cretaceous Qingshuihe Formation in Gaoquan Structure, southern Junggar Basin, NW China显示文摘The complexity of diagenesis and hydrocarbon accumulation in the deep reservoirs in southern Junggar Basin restricts hydrocarbon exploration in the lower reservoir assemblage. The lithofacies and diagenesis of reservoirs in the Cretaceous Qingshuihe Formation in the Gaoquan structure of the Sikeshu Sag, southern Junggar Basin were analyzed. On this basis, the thermal history was calibrated using calcite in-situ U-Pb dating and fluid inclusion analysis to depict the hydrocarbon accumulation process in the Gaoquan structure. The results show that the Qingshuihe reservoir experienced two phases of calcite cementation and three phases of hydrocarbon charging. The calcite cements are dated to be (122.1±6.4) Ma, (14.4±1.0) Ma - (14.2±0.3) Ma. The hydrocarbon charging events occurred at around 14.2-30.0 Ma (low-mature oil), 14.2 Ma (mature oil), and 2 Ma (high-mature gas). The latter two phases of hydrocarbon charging contributed dominantly to the formation of reservoir. Due to the S-N compressive thrust activity during the late Himalayan period since 2 Ma, the traps in the Gaoquan structure were reshaped, especially the effective traps which developed in the main reservoir-forming period were decreased significantly in scale, resulting in weak hydrocarbon shows in the middle-lower part of the structure. This indicates that the effective traps in key reservoir-forming period controlled hydrocarbon enrichment and distribution in the lower reservoir assemblage. Calcite U-Pb dating combined with fluid inclusion analysis can help effectively describe the complex diagenesis and hydrocarbon accumulation process in the central-west part of the basin. | GUI Lili ZHUO Qingong LU Xuesong YANG Wenxia CHEN Weiyan WU Hai FAN Junjia HE Yinjun CAO Rizhou YU Xiaoqing | 2023 | Petroleum Exploration and Development2023，50，6： | 0 |
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