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168篇 您的检索式：作者名="GRAZIANO M"

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	题名	作者	年代	出处	被引量
1	一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.	Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P	2014	中华神经外科疾病研究杂志2014，13，5：	6
2	A role for proteins S3 and S14 in the 30S ribosomal subunit 显示文摘	RAMAKRISHNAN V GRAZIANO V CAPEL M S	1986	J Biol Chem1986，261，15：	1
3	A comparative study of fixation techniches for type Ⅱ fractures of the odontoid process 显示文摘	GRAZIANO G JAGGERS C LEE M	1993	Spine1993，18，：	1
4	Nitric oxide accumulation is required for molecular and physiological responses to iron deficiency in tomato roots显示文摘	Graziano M Lamattina L	2007	Plant J2007，52，5：	1
5	Calcium physiology and metabolism in fruit trees显示文摘	GRAZIANO Z ILARIA M	1995	Acta Horticulturae1995，383，：	1
6	Local invasion of gastric cancer:CT findings and pathologic correlation using 5-mm incremental scanning,hypotonia,and water-filling显示文摘	Rossi M Broglia L Graziano P	1999	AJR1999，172，2：	1
7	Nitric oxide plays a central role in determining lateral root development in tomato 显示文摘	Correa-Aragunde N Graziano M Lamattina L	2004	Planta2004，218，：	1
8	Per- formance Measures and MHT for Tracking Move- Stop-Move Targets with MTI Sensors 显示文摘	Hernandez M Benavoli A Graziano A	2011	IEEE Trans on Aerospace and Electronic Systems2011，47，2：	1
9	An automotive CD-player electro-mechanics fault simulation using VHDL-AMS显示文摘	GRAZIANO M ROCH M R R	2008	Journal of Electronic Testing2008，，6：	1
10	ESD indirect coupling modeling显示文摘	Graziano C Roberto D L Valter M P	1996	IEEE Trans on EMC1996，38，3：	1
11	Expression of matrixmetalloproteinases and their specific inhibitors in normal anddifferent human thyroid tumor cell lines 显示文摘	Baldini E Toiler M Graziano FM	2004	Thyroid2004，14，11：	1
12	Responses of the photosynthetic apparatus of Dunaliella tertiolecta (Chlorophyeeae) to nitrogen and phosphorus limitation显示文摘	Geider R J Macintyre L Graziano L M	1998	European Journal of Phycoiogy1998，33，：	1
13	Metabonomic anal- ysis of saliva reveals generalized chronic periodontitis signature 显示文摘	Aimetti M Cacciatore S Graziano A	2012	Metabolomics2012，8，3：	1
14	A comparative study of fixation techniques for type Ⅱ fractures of the odontoid process 显示文摘	Graziano G Jaggers C Lee M	1993	Spine1993，18，16：	1
15	An algo- rithm for finding signals of unknown lengthinDNAse- quences 显示文摘	GIULIO P GIANCARLO M GRAZIANO P	2001	Bioinformatics2001，4，3：	1
16	Calcium physiology and metabolism in fruit trees显示文摘	Graziano Z Ilaria M	1995	Acta Horticulturae1995，383，：	1
17	Nitric oxide : the versatility of an extensive signal molecule 显示文摘	Lamattina L Garcia - Mata C Graziano M	2003	Annu Rev Plant Biol2003，54，1：	1
18	Human postnatal dental pulp cells co-differentiate into osteoblasts and endotheliocytes: a pivotal synergy leading to aduh bone tissue formation 显示文摘	d'Aquino R Graziano A Sampaolesi M	2007	Cell Death Differ2007，14，6：	1
19	Nitric oxide plays a central role in determining lateral root development in tomato 显示文摘	Correa-Aragunde N Graziano M Lamattina L	2004	Planta2004，218，：	1
20	A new polymorphism in goat beta-laetoglobulin promoter region显示文摘	Graziano M D'Andrea M Angiolillo A	2003	Ital J Anim Sci2003，2，：	1

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