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| 1 | Risk factors associated with pancreatic fistula after distal pancreatectomy, which technique of pancreatic stump closure is more beneficial?显示文摘AIM: To identify risk factors related to pancreatic fistula in patients undergoing distal pancreatectomy (DP) and to determine the effectiveness of using a stapled and a sutured closed of pancreatic stump. METHODS: Sixty-four patients underwent DP during a 10-year period. Information regarding diagnosis, operative details, and perioperative morbidity or mortality was collected. Eight risk factors were examined. RESULTS: Indications for DP included primary pancreatic disease (n = 38, 59%) and non-pancreatic malignancy (n = 26, 41%). Postoperative mortality and morbidity rates were 1.5% and 37% respectively; one patient died due to sepsis and two patients required a reoperation due to postoperative bleeding. Pancreatic fistula was developed in 14 patients (22%); 4 of fistulas were classified as Grade A, 9 as Grade B and only 1 as Grade C. Incidence of pancreatic fistula rate was significantly associated with four risk factors: pathology, use of prophylactic octreotide therapy, concomitant splenectomy, and texture of pancreatic parenchyma. The role that technique (either stapler or suture) of pancreatic stump closure plays in the development of pancreatic leak remains unclear. CONCLUSION: The pancreatic fistula rate after DP is 22%. This is reduced for patients with non-pancreatic malignancy, fibrotic pancreatic tissue, postoperative prophylactic octreotide therapy and concomitant splenectomy. | Marco Pericoli Ridolfini Sergio Alfieri Stavros Gourgiotis Dario Di Miceli Fabio Rotondi Giuseppe Quero Roberta Manghi Giovanni Battista Doglietto | 2007 | World Journal of Gastroenterology2007，13，38： | 24 |
| 2 | Surgical management of chronic pancreatitis显示文摘BACKGROUND: Treatment of chronic pancreatitis (CP) is a challenging condition for surgeons. During the last decades, increasing knowledge about pathophysiology of CP, improved results of major pancreatic resections, and integration of sophisticated diagnostic methods in clinical practice have resulted in significant changes in surgery for CP. DATA SOURCES: To detail the indications for CP surgery, the surgical procedures, and outcome, a Pubmed database search was performed. The abstracts of searched articles about surgical management of CP were reviewed. The articles could be identified and further scrutinized. Further references were extracted by cross-referencing. RESULTS: Main indications of CP for surgery are intractable pain, suspicion of malignancy, and involvement of adjacent organs. The goal of surgical treatment is to improve the quality of life of patients. The surgical approach to CP should be individualized according to pancreatic anatomy, pain characteristics, baseline exocrine and endocrine function, and medical co-morbidity. The approach usually involves pancreatic duct drainage and resection including longitudinal pancreatojejunostomy, pancreatoduodenectomy (Whipple's procedure), pylorus-preserving pancreatoduodenectomy, distal pancreatectomy, total pancreatectomy, duodenum- preserving pancreatic head resection (Beger's procedure), and local resection of the pancreatic head with longitudinal pancreatojejunostomy (Frey's procedure). Non-pancreatic and endoscopic management of pain has also been advocated. CONCLUSIONS: Surgical procedures provide long-term pain relief, a good postoperative quality of life withpreservation of endocrine and exocrine pancreatic function, and are associated with low early and late mortality and morbidity. In addition to available results from randomized controlled trials, new studies are needed to determine which procedure is the most effective for the management of patients with CP. | Stavros Gourgiotis Stylianos Germanos Marco Pericoli Ridolfini | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，2： | 8 |
| 3 | Gallbladder cancer显示文摘 | Stavros Gourgiotis Hemant M. Kocher Leonardo Solaini Arvin Yarollahi Evangelos Tsiambas Nikolaos S. Salemis | 2008 | The American Journal of Surgery2008，，2： | 2 |
| 4 | Is there a changing trend in surgical management of gastroesophageal reflux disease in children?显示文摘Gastroesophageal reflux disease (GORD) is a pathological process in infants manifesting as poor weight gain, signs of esophagitis, persistent respiratory symptoms and changes in neurobehaviour. It is currently estimated that approximately one in every 350 children will experience severe symptomatic gastroesophageal reflux necessitating surgical treatment. Surgery for GORD is currently one of the common major operations performed in infants and children. Most of the studies found favour laparoscopic approach which has surpassed open antireflux surgery as the gold standard of surgical management for GORD.However, it must be interpreted with caution due to the limitation of the studies, especially the small number of subject included in these studies. This review reports the changing trends in the surgical treatment of GORD inchildren. | Mahmud Saedon Stavros Gourgiotis Stylianos Germanos | 2007 | World Journal of Gastroenterology2007，13，33： | 2 |
| 5 | The effect of intrauterine growth restriction on circulating surfactant protein d concentrations in the perinatal period显示文摘 | Briana DD Gourgiotis D Baka S | 2010 | Reprod Sci2010，17，7： | 1 |
| 6 | Operative and nonoperative management of blunt hepatic trauma in adults a single center repor显示文摘 | Gourgiotis S Vougas V Germanos S | 2007 | J Hepatobiliary Pancreat Surg2007，14，4： | 1 |
| 7 | Role of visfatin,insulin-like growth factor-1 and insulin in fetal growth显示文摘 | Briana DD Boutsikou M Gourgiotis D | | 0，，： | 1 |
| 8 | Inadvertent parathyroidectomy during thyroid surgery:the incidence of a complication of thyroidectomy显示文摘 | Gourgiotis S Moustafellos P Dimopoulos N | 2006 | Langenbecks Arch Surg2006，391，6： | 1 |
| 9 | Mid-trimester amniotic fluid interleukins(IL-1β, IL-10 and IL-18)as possible predictors of preterm delivery显示文摘 | Puchner K Iavazzo C Gourgiotis D | 2011 | In Vivo2011，25，1： | 1 |
| 10 | Acute limb compartment syndrome : a review 显示文摘 | Gourgiotis S Villias C Germanos S | 2007 | J Surg Educ2007，64，3： | 1 |
| 11 | Clara cell protein in full-term pregnancies: the influence of intrauterine growth restrietion显示文摘 | Briana DD Gourgiotis D Boutsikou M | 2010 | Pediatr Pulmonol2010，45，： | 1 |
| 12 | Immune modulator pidoti-mod decreases the in vitro expression of CD30 in peripheral bloodmononuclear cells of atopic asthmatic and normal children 显示文摘 | Gourgiotis D Papadopoulos NG Bossios A | 2004 | Asth-ma2004，41，3： | 1 |
| 13 | Blood visfatin concentrations in normal full-term pregnancies 显示文摘 | Malamitsi-Puchner A Briana DD Gourgiotis D | 2007 | Acta Paediatr2007，96，4： | 1 |
| 14 | Operative and non- operative blunt hepatic trauma in adults: a single-center report 显示文摘 | Gourgiotis S Vougas V Germanos S | 2007 | J Hepatobiliary Pancreat Surg2007，14，3： | 1 |
| 15 | Gallbladder cancer显示文摘 | Gourgiotis S Kocher H M Solaini L | | 0，，02： | 1 |
| 16 | Laparoscopic cholecystectomy:a safe approach for management of acute cholecystitis显示文摘 | GOURGIOTIS S DIMOPOULOS N GERMANOS S | | 0，，02： | 1 |
| 17 | Rectal prolapse显示文摘 | Gourgiotis S Baratsis S | 2007 | Int J Colorectal Dis2007，22，3： | 1 |
| 18 | Endothelin I levels in relation to clinical presentation and outcome of Henoch Schonlein purpura显示文摘 | Fessatou S Nicolaidou P Gourgiotis D | 2008 | BMC Pediatr2008，8，1： | 1 |
| 19 | Operative and nonoperative management of blunt hepatic trauma in adults: a single-center report 显示文摘 | Gourgiotis S Vougas V Germanos S etal | 2007 | J Hepatohiliary Pancreat Surg2007，14，4： | 1 |
| 20 | Serum fetuin-A/alpha 2-HS-glycoprotein in human pregnancies pregnan-cies with normal and restricted fetal growth显示文摘 | Briana DD Boutsikou M Gourgiotis D | 2008 | J Matern Fe-tal Neonatal Med2008，21，11： | 1 |
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