|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 小型轿车用福特DIATA柴油机的设计和开发显示文摘福特汽车公司研究实验室和德国FEV发动机技术公司合作,正在开发一种崭新的高速直喷式柴油机。它是美国能源部混合动力驱动系统开发计划的一部分。这种柴油机利用多种先进技术和创新的设计思想,将配有这种柴油机的福特P2000型混合动力电动概念车能满足非常严格的排放、燃料经济性和使用性能指标。这种柴油机的设计也适应了用传统的制造和装配设施,以可接受的成本进行批量生产的要求,采用常用的材料和生产工艺。本文将讨论该柴油机设计的一些特殊细节,如机体结构、气缸盖设计、NVH(噪声、振动和行驶不平顺性)的对策、以及支承设计方案的一些分析研究和硬件试验。此外,还将报告一些初期开发试验结果。 | Gomes E D Ecker H J Schellhase T 刘巽俊 | 1999 | 国外内燃机1999，31，5： | 3 |
| 2 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 3 | A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘 | Juurlink DN Gomes T Ko DT | 2009 | CM AJ2009，180，7： | 1 |
| 4 | Erros in ground distortions due to settlement trough adjustment显示文摘 | CELESTINO T B GOMES R A M P and BORTOLUCCI A A | 2000 | Tunneling and underground Space Technology2000，15，1： | 1 |
| 5 | Microorganisms from canals of root-filled teeth with periapical lesions显示文摘 | PINHEIRO E T GOMES B P FERRAZ C C | 2003 | Int Endod J2003，36，1： | 1 |
| 6 | Fate of oxi- dized triglycerides during refining of seed oils 显示文摘 | GOMES T CAPONIO F DELCURATOLO D | 2003 | J Agric Food Chem2003，51，16： | 1 |
| 7 | The risk of hypotension following co-prescription of macrolide antibiotics and cacium-channel blockers显示文摘 | Wright A J Gomes T Mamdani MM | | 0，，： | 1 |
| 8 | In vitro antibacterial screening of Cryptolepis sanguinolenta alkaloids 显示文摘 | Paulo A Duarte A Gomes E T | 1994 | J Ethnopharmacol1994，44，2： | 1 |
| 9 | Rates of hemorrhage during warfarin therapy for atrial fibrillation显示文摘 | Gomes T Mamdani MM Holbrook AM | 2013 | CMAJ2013，185，2： | 1 |
| 10 | A population-based study of the drug interaction between proton pump inhibitors and clopidogrel显示文摘 | Juurlink DN Gomes T Ko DT | 2009 | CMAJ2009，180，7： | 1 |
| 11 | Physical Distribution Service:A Fundamental Marketing Concept 显示文摘 | Mentzer J T Gomes R Krapfel R E | 1989 | Journal of the Academy of MarketingScience1989，17，4： | 1 |
| 12 | Oligopolymer, diglyceride and oxidized triglyc- eride contents as measures of olive oil quality 显示文摘 | GOMES T | 1992 | J Am Oil Chem Soc1992，69，12： | 1 |
| 13 | Hydrogen peroxide pre - treatment induces salt - stress acclimation in maize plants 显示文摘 | Neto A D de A Prisco J T Eneas - Filho J Medeiros J V R Gomes -Filho E | 2005 | Journal of Plant Physiology2005，162，10： | 1 |
| 14 | Activated carbons treated with sulphuric acid : Catalystsfor catalytic wet peroxide oxidation显示文摘 | Gomes Helder T Miranda Sandra M Sampaio Maria J etal | 2010 | Catal Today2010，151，12： | 1 |
| 15 | A population- based study of the drug interaction between proton pump in- hibitors and clopidogrel显示文摘 | Juurlink D N Gomes T Ko D T | 2009 | CMA J2009，180，7： | 1 |
| 16 | Separation of biodiesel and glycerol using ceramic membranes显示文摘 | SERGI GOMES M C PEREIRA N C DAVANTEL DE BARROS S T | 2010 | JournalofMembraneScience2010，352，2： | 1 |
| 17 | Optimal inspection planning for onshore pipelines subject to external corrosion显示文摘 | Gomes W J S Beck A T Haukaas T | 2013 | Reliability Engineering & System Safety2013，118，： | 1 |
| 18 | Errors in ground distortions due to settlement trough adjustment显示文摘 | Celestino T B Gomes R A M P Bortolucci A A | 2000 | Tunnelling and Underground Space Technology2000，15，1： | 1 |
| 19 | Synthesis and characterization of tetrahedral and square planar bis (iminopyrrolyl) complexes of cobalt ( Ⅱ ) 显示文摘 | Carabineiro S A Silva L C Gomes P T | 2007 | Inorg Chem2007，46，： | 1 |
| 20 | Photovoltaic potential in a Lisbon suburb using LiDAR data显示文摘 | Brito M C Gomes N Santos T | 2012 | Solar Energy2012，86，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员