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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Association of Helicobacter pylori infection and giardiasis: Results from a study of surrogate markers for fecal exposure among children显示文摘AIM: To investigate whether Helicobacter pylori (H pykori)infection is associated with hepatitis A virus (HAV) infection, presence of enteroparasites, and other surrogates of fecal exposure.METHODS: We conducted a cross-sectional study in 121 children consecutively admitted at a pediatric hospital inSalvador, Brazil.H pylori and HAV infection were identified by the presence of serum antibodies. Stool specimens were examined for the presence of ova and parasites. A structured questionnaire inquiring about sanitary conditions and life style was applied to each subject. RESULTS: Fifty-one of the 121 children (42.1%) werefound to be seropositive for H pylori, and 45 (37.2%) for HAV. The seroprevalence ofHpyloriand HAV both increased significantly with age. Cross-tabulation of data showed that 26 (21.5%) were seropositive and 51 (42.1%) were negative for bothHpyloriand HAV antibodies (χ2 = 7.18,OR = 2.8, CI 1.30-5.97). The age adjusted OR for an HAV-infected child being H pylori positive was 2.3 (CI1.02-5.03). The agreement between H pylori and HAVseropositivity was fair (κ = 0.24). After controlling for possible confounding, the variables remaining independently associated with seropositivity to H pyloriwere age,presence of Giardia lamblia in feces (OR = 3.2, 95%CI, 1.1-9.5) and poor garbage disposal quality (OR = 2.4,95%CI, 1.1-5.1).CONCLUSION: Our data suggest that H pylori infection is associated with surrogate markers of fecal exposure. Thus, we conclude that the fecal-oral route is relevant in the transmission of HP among children in an urban setting of a developing country. The association observed between G. lamblia and H pylori infection may have several explanations. Further studies to investigate this relationship are warranted. | Edson Duarte Moreira Jr Victor Bastos Nassri Rafaela Sousa Santos Junísia Ferraz Matos Wilson Andrade de Carvalho Célia Stolve Silvani Círia Santana e Sant'Ana | 2005 | World Journal of Gastroenterology2005，11，18： | 3 |
| 3 | Microorganisms from canals of root-filled teeth with periapical lesions显示文摘 | PINHEIRO E T GOMES B P FERRAZ C C | 2003 | Int Endod J2003，36，1： | 1 |
| 4 | Surgical anatomy of the external branch of the superior laryngeal nerve 显示文摘 | Cernea C R Ferraz A R Nishio S | 1992 | Head Neck1992，14，5： | 1 |
| 5 | Name Reactions for Carbocyclic Ring Formations 显示文摘 | FERRAZ H M C BIANCO G G TEIXEIRA C | 2007 | Tetrahedron Asymmetry2007，18，12： | 1 |
| 6 | Amin- ophylline affects glycemia control and increases anaerobic gly- colysis in horses during incremental exercise显示文摘 | Ferraz G C Teixeira-Neto A R Lacerda-Neto J C etal | 2008 | Journal of E- quine Veterinary Science2008，28，7： | 1 |
| 7 | Hospital-acquired me- ningitis in patients undergoing craniotomy: incidence, evolution, and risk factors显示文摘 | Reichert M C Medeiros E A Ferraz F A | 2002 | Am J Infect Control2002，30，3： | 1 |
| 8 | Apical ntrusion of debris and irrigants using two hand and three engine-driven instrumentation techniques 显示文摘 | Ferraz C C Gomes N V Gomes B P | 2001 | Int Endod J2001，34，5： | 1 |
| 9 | Current state and future perspective of molecular diagnosis of fine-needle aspira- tion biopsy of thyroid nodules 显示文摘 | Ferraz C Eszlinger M Paschke R | 2011 | J Clin Endocrinol Metab2011，96，7： | 1 |
| 10 | Guidelines for the process of cross-cultural adaptation of self-report measures显示文摘 | Beaton DE Bombardier C Guillemin F Ferraz MB | 2000 | Spine (Phila Pa 1976)2000，25，24： | 1 |
| 11 | Landscape dynamics of Amazonian deforestation between 1984 and 2002 in central Rondonia, Brazil: assessment and future scenarios显示文摘 | Ferraz S F B Vettorazzi C A Theobald D M | 2005 | Forest Ecology and Management2005，204，： | 1 |
| 12 | Quercetin in- duces structural chromosomal aberrations and uncom- mon rearrangements in bovine cells transformed by the E7 protein of bovine papillomavirus type 4显示文摘 | Leal A M Ferraz O P Carvalho C | 2003 | Vet Comp Onco12003，1，1： | 1 |
| 13 | Microbiological analysis of infected root canals from symptomatic and asymptomatic teeth with periapical periodontitis and the antimicrobial susceptibility of some isolated anaerobic bacteria 显示文摘 | JACINTO R C GOMES B P FERRAZ C C | 2003 | Oral Microbial Immunol2003，18，5： | 1 |
| 14 | The Kauffman model on smallworld topology显示文摘 | Ferraz C H A Herrmann H J | 2006 | Physica A:Statistical Mechanics and its Applications In Press Corrected Proof2006，17，： | 1 |
| 15 | Acute respiratory distress syndrome in a child with human parvovirus B19 infection显示文摘 | Ferraz C Cunha F Mota TC | 2005 | Pediatr Infect Dis J2005，24，11： | 1 |
| 16 | Evaluation of root canal microorganisms isolated from teeth with endodontic failure and their antimicrobial susceptibility显示文摘 | PINHEIRO E T GOMES B P FERRAZ C C | 2003 | Oral Microbiol Immunol2003，18，2： | 1 |
| 17 | Hospital-acquired meningi- tis in patients undergoing craniotomy: incidence, evolution, and risk factors显示文摘 | Reichert M C Medeiros E A Ferraz F A | 2002 | Am J Infect Control2002，30，3： | 1 |
| 18 | Inverse correlation of miR and cell ey- rie-associated genes suggests influence of miR on benign thyroid nodule tumorigenesis显示文摘 | Ferraz C Lorenz S Wojtas B | 2013 | J Clin Endocrinol Metab2013，98，1： | 1 |
| 19 | Static and dynamic analysis of theanterior segment with optical coherence tomography 显示文摘 | Baikoff G Lutun E Ferraz C | 2004 | J Cata-ract Refract Surg2004，30，： | 1 |
| 20 | Static and dynamic analysis of the anterior segment with optical coherence tomography显示文摘 | Baikoff G Lutun E Ferraz C | 2004 | J Cata- ract Refract Surg2004，30，： | 1 |
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